Antinuclear antibody-negative systemic lupus erythematosus. I. Anti-Ro(SSA) and anti-La(SSB) antibodies.

abstract：BACKGROUND:Dermatomyositis affects visible skin and causes disease symptoms that can affect patients' quality of life (QOL). METHODS:In all, 71 patients with dermatomyositis or dermatomyositis sine myositis completed two QOL measures (the Skindex-16 and the Dermatology Life Quality Index) and a visual analog scale for...

journal_title：Journal of the American Academy of Dermatology

authors： Hundley JL,Carroll CL,Lang W,Snively B,Yosipovitch G,Feldman SR,Jorizzo JL

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:There is large variability in the risk of sentinel lymph node (SLN) positivity among patients with intermediate thickness melanoma (ITM), with a subgroup of patients exhibiting a low risk of nodal disease. OBJECTIVE:To identify a group of patients with ITM for whom the risk of nodal disease is low. METHODS...

journal_title：Journal of the American Academy of Dermatology

authors： Hanna AN,Sinnamon AJ,Roses RE,Kelz RR,Elder DE,Xu X,Pockaj BA,Zager JS,Fraker DL,Karakousis GC

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Cholinergic urticaria is primarily seen in young adults, but little is known about its prevalence. OBJECTIVE:A prospective study was designed to investigate the frequency and severity of cholinergic urticaria in this age group. METHODS:Four hundred ninety-three high school and university students (15 to 35...

journal_title：Journal of the American Academy of Dermatology

authors： Zuberbier T,Althaus C,Chantraine-Hess S,Czarnetzki BM

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Little is known about the utilization of medical services for psoriasis. OBJECTIVE:Our purpose was to quantify the medical resources utilized in the United States for the treatment of psoriasis. METHODS:By utilizing data tapes from the National Center of Health Statistics we estimated the number of outpati...

journal_title：Journal of the American Academy of Dermatology

authors： Stem RS

更新日期：1996-10-01 00:00:00

abstract：:Metastatic Crohn's disease (CD) is a rare cutaneous manifestation of CD that was first described nearly 50 years ago. Many subsequent reports have defined its most common clinical and histopathologic features. The pathogenesis underlying metastatic CD is unknown but various hypotheses exist. An established standard th...

journal_title：Journal of the American Academy of Dermatology

authors： Kurtzman DJ,Jones T,Lian F,Peng LS

更新日期：2014-10-01 00:00:00

abstract：:A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz BC,Roenigk HH Jr

更新日期：1982-10-01 00:00:00

abstract：:Seborrheic dermatitis is generally treated with topical steroids, antifungals, or both. This pilot study was undertaken to examine the possibility of tacrolimus as a useful therapy for seborrheic dermatitis. In a single-center, open-label study, 18 consecutive patients with seborrheic dermatitis were treated with 0.1%...

journal_title：Journal of the American Academy of Dermatology

authors： Meshkinpour A,Sun J,Weinstein G

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Silverberg AI,Malka E,Silverberg NB

更新日期：2010-06-01 00:00:00

abstract：:Cytokines are glycoproteins produced by many different cells. Via binding to specific receptors on target cells they regulate the activation, differentiation, and proliferation of immune and nonimmune cells. After injury keratinocytes synthesize and release cytokines such as interleukins, colony stimulating factors, a...

journal_title：Journal of the American Academy of Dermatology

authors： Luger TA,Schwarz T

更新日期：1991-06-01 00:00:00

abstract：:Chemotherapy-induced alopecia is a distressing side effect common to certain treatment regimens in oncology. Unfortunately, chemotherapy-induced alopecia is an often overlooked or minor factor among our current research priorities and thus advances in amelioration have been minimal. This review offers a comprehensive ...

journal_title：Journal of the American Academy of Dermatology

authors： Chon SY,Champion RW,Geddes ER,Rashid RM

更新日期：2012-07-01 00:00:00

abstract：:Topical nitrogen mustard is an alkylating agent. Its efficacy in treating alopecia areata was reported in an uncontrolled study. We present a preliminary, half-head, controlled 16-week study showing that topical nitrogen mustard was of benefit in 1 of 6 patients treated with 50% to 100% scalp involvement. Another 4 pa...

journal_title：Journal of the American Academy of Dermatology

authors： Bernardo O,Tang L,Lui H,Shapiro J

更新日期：2003-08-01 00:00:00

abstract：:Kawasaki disease, or mucocutaneous lymph node syndrome, is the leading cause of acquired heart disease in children in the United States and other developed countries. Coronary artery lesions are the most significant cause of morbidity and mortality. Treatment should ideally be provided within 10 days of symptom onset ...

journal_title：Journal of the American Academy of Dermatology

authors： Bayers S,Shulman ST,Paller AS

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Deep nasal defects of the dorsum, sidewall, and ala can be challenging to repair. OBJECTIVE:The article describes our experience with a muscle hinge transposition flap with overlying local full-thickness skin grafting for repair of deep nasal defects in a single-stage procedure. METHODS:A muscle hinge tran...

journal_title：Journal of the American Academy of Dermatology

authors： Fader DJ,Wang TS,Johnson TM

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:A radiofrequency-controlled electrosurgical device (ESD) has been adapted for skin peeling. A high-voltage, low-amperage current converts an irrigant into an ionized vapor, causing molecular dissociation and superficial damage in adjacent tissue. OBJECTIVE:We compared the clinical and histologic effects of ...

journal_title：Journal of the American Academy of Dermatology

authors： Acland KM,Calonje E,Seed PT,Stat C,Barlow RJ

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Physician visits provide invaluable opportunities to screen patients for skin cancer, yielding earlier detection and improved survival. OBJECTIVE:We sought to assess frequency of skin cancer screening by full body skin examinations (FBSE) by primary care physicians, patient attitudes toward FBSE, and risk f...

journal_title：Journal of the American Academy of Dermatology

authors： Rodriguez GL,Ma F,Federman DG,Rouhani P,Chimento S,Multach M,Kirsner RS

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Onychomatricoma (OM) is a rare benign tumor of the nail matrix in which genome-wide analyses have never been performed. It is clinically characterized by an increased transversal curvature of the nail plate, a longitudinal yellowish discoloration, and splinter hemorrhages. Once the nail plate has been remove...

journal_title：Journal of the American Academy of Dermatology

authors： Cañueto J,Santos-Briz Á,García JL,Robledo C,Unamuno P

更新日期：2011-03-01 00:00:00

abstract：:Squamous cell carcinoma of the penis is almost exclusively a lesion of uncircumcised older men. It represents about 1% of cancers in men in the United States and 11% to 12% of all cancers in men in countries where circumcision is not routinely practiced. Verrucous carcinoma is an uncommon variant that accounts for onl...

journal_title：Journal of the American Academy of Dermatology

authors： Kanik AB,Lee J,Wax F,Bhawan J

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00

abstract：:Familial multiple lipomatosis is a hereditary syndrome of multiple lipomas occurring in a particular distribution. It is clinically distinct from multiple symmetric lipomatosis with which it is frequently confused in the dermatologic literature. A case of familial multiple lipomatosis is reported and a review of this ...

journal_title：Journal of the American Academy of Dermatology

authors： Leffell DJ,Braverman IM

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD), a chronic, highly pruritic skin disorder, impairs quality of life (QoL). Janus kinase inhibitors suppress inflammatory and pruritus-associated cytokine signaling in AD. OBJECTIVE:To report the effects of ruxolitinib (RUX) cream on itch and QoL in AD. METHODS:A total of 307 adult pat...

journal_title：Journal of the American Academy of Dermatology

authors： Kim BS,Sun K,Papp K,Venturanza M,Nasir A,Kuligowski ME

更新日期：2020-06-01 00:00:00

abstract：:The effect of drug concentrations of 2.5%, 5%, and 10% upon the transepidermal penetration of 14C-benzoyl peroxide in a lotion vehicle was assessed in excised human skin and in vivo in the rhesus monkey. In vitro, penetration of benzoyl peroxide was concentration-dependent, both as to rate and to amount, as measured b...

journal_title：Journal of the American Academy of Dermatology

authors： Yeung D,Nacht S,Bucks D,Maibach HI

更新日期：1983-12-01 00:00:00

abstract：:New and relatively old types of vascular (capillary) proliferations in the skin have been described or better categorized in the last few years. They include reactive angioendotheliomatosis, acroangiodermatitis (pseudo-Kaposi sarcoma), diffuse dermal angiomatosis, intravascular histocytosis, glomeruloid angioendotheli...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：2003-11-01 00:00:00

abstract：:The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of t...

journal_title：Journal of the American Academy of Dermatology

authors： Duvic M,Asano AT,Hager C,Mays S

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:There is growing evidence that Mohs micrographic surgery (MMS) is the treatment of choice for dermatofibrosarcoma protuberans (DFSP). OBJECTIVE:This study retrospectively compared the recurrence rates of DFSP after MMS with those after wide surgical excision; results at the Mayo Clinic and in the world lite...

journal_title：Journal of the American Academy of Dermatology

authors： Gloster HM Jr,Harris KR,Roenigk RK

更新日期：1996-07-01 00:00:00

abstract：:The clinical and histologic spectrum of melanotic macule of the nail unit is examined and the differences in the clinical appearance of longitudinal melanochychia caused by melanotic macule and by other kinds of proliferations of melanocytes are assessed. We observed that the clinical appearance of the pigmented band ...

journal_title：Journal of the American Academy of Dermatology

authors： Husain S,Scher RK,Silvers DN,Ackerman AB

更新日期：2006-04-01 00:00:00

abstract：:We describe a case of generalized, asymptomatic, chronic annular lichen planus. The centers of the large annular lesions were atrophic and had lost their elasticity. Histologic examination revealed an absence of elastic fiber in the center. Electron microscopy revealed fragmented elastic fibers. Examination of early l...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman DB,Hashimoto K

更新日期：1991-08-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a treatment based on the accumulation of a photosensitizer in the target cells and their selective destruction by irradiation with visible light. In the past 10 years, several patients with cutaneous T cell lymphoma have been successfully treated. The use of PDT in cutaneous B cell lympho...

journal_title：Journal of the American Academy of Dermatology

authors： Mori M,Campolmi P,Mavilia L,Rossi R,Cappugi P,Pimpinelli N

更新日期：2006-03-01 00:00:00

abstract：:Patients with dark skin can present with morphologic variants, subtle disease presentations, and disease manifestations requiring unique management and therapies. With African Americans, Asians, and Hispanic Americans becoming a significant portion of the population, dermatologists must be able to diagnose and manage ...

journal_title：Journal of the American Academy of Dermatology

authors： Ebede T,Papier A

更新日期：2006-10-01 00:00:00

abstract：:A randomized double-blind trial of topical minoxidil was carried out during a 12-month period in 56 patients with male pattern baldness. Subjects were randomly assigned to treatment with either 2% minoxidil solution, 3% minoxidil solution, or placebo. The placebo group was switched to 3% minoxidil after the first 4 mo...

journal_title：Journal of the American Academy of Dermatology

authors： De Villez RL

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Intraoperative pain during Mohs micrographic surgery (MMS) has not been characterized. However, many patients report postoperative pain on the day of MMS. OBJECTIVE:We sought to determine if patients experience pain during their MMS visit. METHODS:In phase I of this study, patients were asked to report int...

journal_title：Journal of the American Academy of Dermatology

authors： Connolly KL,Nehal KS,Dusza SW,Rossi AM,Lee EH

更新日期：2016-09-01 00:00:00