Familial multiple lipomatosis. Report of a case and a review of the literature.

abstract：:We observed the course of development of porokeratosis stimulated by benzylhydrochlorothiazide (BHCTh) in normal-appearing skin of a patient with long-standing stable porokeratosis of Mibelli. A 72-year-old Japanese man had had porokeratosis of Mibelli for more than 50 years. During administration of BHCTh for 1 year ...

journal_title：Journal of the American Academy of Dermatology

authors： Inamoto N,Watanabe T,Nakamura K

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Skin ulcers are common vascular complications of systemic sclerosis (SSc). OBJECTIVE:The aim of the study was to identify clinical, biologic, and imaging parameters that constitute risk factors for the occurrence and persistence of skin ulcers. METHODS:One hundred thirty Italian SSc patients were examined ...

journal_title：Journal of the American Academy of Dermatology

authors： Alivernini S,De Santis M,Tolusso B,Mannocci A,Bosello SL,Peluso G,Pinnelli M,D'Antona G,La Torre G,Ferraccioli G

更新日期：2009-03-01 00:00:00

abstract：:We report the case of a 29-year-old transsexual who developed Mycobacterium abscessus infection after receiving intramammary liquid silicone injections in the nonphysician office setting. Our patient represents 1 of 14 confirmed and 11 suspected cases in New York City of M abscessus infection after illicit cosmetic pr...

journal_title：Journal of the American Academy of Dermatology

authors： Fox LP,Geyer AS,Husain S,Della-Latta P,Grossman ME

更新日期：2004-03-01 00:00:00

abstract：:Palliative care has been shown to improve quality of life, symptom, and caregiver burden for a range of life-limiting diseases. Palliative care use among patients with severe dermatologic disease remain relatively unexplored, but the limited available data suggest significant unmet care needs and low rates of palliati...

journal_title：Journal of the American Academy of Dermatology

authors： Thompson LL,Chen ST,Lawton A,Charrow A

更新日期：2020-08-12 00:00:00

abstract：:Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type 1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide a practical approach to using T-VEC in the dermatologic surgery and oncolo...

journal_title：Journal of the American Academy of Dermatology

authors： Haitz K,Khosravi H,Lin JY,Menge T,Nambudiri VE

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Germain M,Yeager J,Skelton H

更新日期：2002-10-01 00:00:00

abstract：:Sixty-six confirmed cases of Bowen's disease (intraepidermal squamous cell carcinoma) were seen from 1965 through 1976: twenty-four cases were treated surgically-four by excision (two recurrences) and twenty by desiccation and curettage (four recurrences); one was treated with x-ray radiation; and forty-one were treat...

journal_title：Journal of the American Academy of Dermatology

authors： Sturm HM

更新日期：1979-12-01 00:00:00

abstract：:The clinical and histologic spectrum of melanotic macule of the nail unit is examined and the differences in the clinical appearance of longitudinal melanochychia caused by melanotic macule and by other kinds of proliferations of melanocytes are assessed. We observed that the clinical appearance of the pigmented band ...

journal_title：Journal of the American Academy of Dermatology

authors： Husain S,Scher RK,Silvers DN,Ackerman AB

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE:We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze fact...

journal_title：Journal of the American Academy of Dermatology

authors： Mora AN,Karia PS,Nguyen BM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Reducing people's exposure to ultraviolet radiation is the primary strategy for skin cancer prevention. OBJECTIVE:We sought to provide comprehensive national data on preventive behaviors and risk assessment for Australia. METHODS:A national survey was conducted in summer 2003-2004. In 8 weekly cross-sectio...

journal_title：Journal of the American Academy of Dermatology

authors： Dobbinson S,Wakefield M,Hill D,Girgis A,Aitken JF,Beckmann K,Reeder AI,Herd N,Fairthorne A,Bowles KA

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:HLA-DR1 is associated with the development of multiple basal cell carcinomas (BCC). However, the association is weak. OBJECTIVE:The purpose of our study was to determine whether HLA-DR1 is a marker for susceptibility to the development of many BCCs during a lifetime. METHODS:Persons with multiple BCCs were...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B,Nash C

更新日期：1992-05-01 00:00:00

abstract：:A 45-year-old woman developed chronic urticaria clinically and cutaneous necrotizing vasculitis histologically, with arthralgias, abdominal pain, angioedema, hemoptysis, and pleuritic chest pain. An open lung biopsy revealed a leukocytoclastic vasculitis of the pulmonary venules, which may be etiologically associated ...

journal_title：Journal of the American Academy of Dermatology

authors： Falk DK

更新日期：1984-08-01 00:00:00

abstract：OBJECTIVE:We sought to develop a validated, reliable pruritus-specific quality-of-life (QOL) instrument, ItchyQoL. METHODS:From 21 in-depth interviews with patients with pruritus, we developed 22 pruritus-specific items, and hypothesized 3 major constructs that explain the way pruritus affects patients' QOL: symptoms,...

journal_title：Journal of the American Academy of Dermatology

authors： Desai NS,Poindexter GB,Monthrope YM,Bendeck SE,Swerlick RA,Chen SC

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. OBJECTIVE:We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for pa...

journal_title：Journal of the American Academy of Dermatology

authors： Zug KA,Rietschel RL,Warshaw EM,Belsito DV,Taylor JS,Maibach HI,Mathias CG,Fowler JF Jr,Marks JG Jr,DeLeo VA,Pratt MD,Sasseville D,Storrs FJ

更新日期：2008-09-01 00:00:00

abstract：:To develop guidelines for the follow-up of patients with primary cutaneous melanoma (clinical Stage I), we studied 295 patients who had presented with a primary melanoma and who subsequently developed evidence of metastatic disease in the course of follow-up. Cox multivariate analysis was used to assess the influence ...

journal_title：Journal of the American Academy of Dermatology

authors： Kelly JW,Blois MS,Sagebiel RW

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:In primary melanomas, data on the degree of intratumoral heterogeneity to date have been lacking. OBJECTIVE:Our purpose was to investigate intratumoral DNA stem-line heterogeneity in superficial spreading melanoma (SSM). METHODS:Multiple measuring fields of 54 SSMs (tumor thickness median 1.60 mm) were stu...

journal_title：Journal of the American Academy of Dermatology

authors： Helmbold P,Altrichter D,Klapperstück T,Marsch WCh

更新日期：2005-05-01 00:00:00

abstract：:A 40-year-old man with severe psoriasis developed painless muscle stiffness coinciding with four successive courses of etretinate therapy. Peripheral nerve block extinguished the increased muscle tone. Our patient's symptoms resembled those of the stiff-man syndrome. Increased muscle tone is a potential side effect of...

journal_title：Journal of the American Academy of Dermatology

authors： Ellis CN,Gilbert M,Cohen KA,Albers JW,Ball RD,Albin RL,Silverman A,Voorhees JJ

更新日期：1986-05-01 00:00:00

abstract：:Lipedema is characterized by symmetric lower extremity enlargement secondary to the deposition of fat. Lipedema is not rare, but it is commonly misdiagnosed as lymphedema. We describe a 20-year-old woman with massive lower extremity enlargement that did not respond to compression therapy. Magnetic resonance imaging of...

journal_title：Journal of the American Academy of Dermatology

authors： Fonder MA,Loveless JW,Lazarus GS

更新日期：2007-08-01 00:00:00

abstract：:An unusual American epidemic consisting of twenty cases of granuloma inguinale is chronicled. Evidence from this series supports the venereal transmission of the disorder. Trimethoprim/sulfamethoxazole proved to be a safe and effective therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Tschen JA,Ramsdell W,Moore J,Markham B

更新日期：1984-09-01 00:00:00

abstract：:Malignant melanoma is considered the most lethal skin cancer if it is not detected and treated during its early stages. About 10% of melanoma patients report a family history of melanoma; however, individuals with features of true hereditary melanoma (ie, unilateral lineage, multigenerational, multiple primary lesions...

journal_title：Journal of the American Academy of Dermatology

authors： Soura E,Eliades PJ,Shannon K,Stratigos AJ,Tsao H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The Food and Drug Administration (FDA) has received reports of depression and suicide in patients treated with isotretinoin. OBJECTIVE:Our purpose was to provide the number and describe the cases of depression and suicide reported to the FDA in US patients treated with isotretinoin and to consider the natur...

journal_title：Journal of the American Academy of Dermatology

authors： Wysowski DK,Pitts M,Beitz J

更新日期：2001-10-01 00:00:00

abstract：:We report a case of epidermodysplasia verruciformis (EV)-like lesions in a patient with graft-versus-host disease after peripheral blood stem cell transplantation from his HLA-matched brother. The patient presented with a diffuse papular eruption that was clinically consistent with graft-versus-host disease; however, ...

journal_title：Journal of the American Academy of Dermatology

authors： Kunishige JH,Hymes SR,Madkan V,Wyatt AJ,Uptmore D,Lazar AJ,Giralt S,Rady P,Tyring S

更新日期：2007-11-01 00:00:00

abstract：:We present the identification and characterization of two patients with xeroderma pigmentosum (XP) and squamous cell carcinoma of the tongue. Dermal fibroblasts from two black siblings with XP were shown to be hypersensitive to ultraviolet (UV) light measured by colony-forming ability. UV-induced unscheduled deoxyribo...

journal_title：Journal of the American Academy of Dermatology

authors： Wade MH,Plotnick H

更新日期：1985-03-01 00:00:00

abstract：UNLABELLED:Skin cancer is the most common cancer in human beings. The increased incidence of skin cancer has brought much attention to the process by which these tumors develop and how they can be prevented. Efforts have been made to educate the public about the importance of protecting skin from excessive ultraviolet ...

journal_title：Journal of the American Academy of Dermatology

authors： Wright TI,Spencer JM,Flowers FP

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Current knowledge of angiolymphoid hyperplasia with eosinophilia (ALHE) derives from retrospective reports and case series, leading to a nonevidence-based treatment approach. OBJECTIVE:We sought to systematically review the literature relating to cutaneous ALHE to estimate its epidemiology and treatment out...

journal_title：Journal of the American Academy of Dermatology

authors： Adler BL,Krausz AE,Minuti A,Silverberg JI,Lev-Tov H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Despite increasing therapies for moderate to severe psoriasis, dermatologists' treatment preferences are unknown. OBJECTIVE:We sought to assess dermatologists' preferences for first-line treatments and their selection determinants. METHODS:We surveyed 1000 US dermatologists (500 National Psoriasis Foundati...

journal_title：Journal of the American Academy of Dermatology

authors： Wan J,Abuabara K,Troxel AB,Shin DB,Van Voorhees AS,Bebo BF Jr,Krueger GG,Callis Duffin K,Gelfand JM

更新日期：2012-03-01 00:00:00

abstract：:Patients with dark skin can present with morphologic variants, subtle disease presentations, and disease manifestations requiring unique management and therapies. With African Americans, Asians, and Hispanic Americans becoming a significant portion of the population, dermatologists must be able to diagnose and manage ...

journal_title：Journal of the American Academy of Dermatology

authors： Ebede T,Papier A

更新日期：2006-10-01 00:00:00

abstract：:A 46-year-old white man had classic findings of scleredema; subsequently, a monoclonal immunoglobulin G lambda light chain was detected in his serum. Findings of a bone marrow biopsy specimen revealed that he had an increased percentage of plasma cells, some of which were atypical. A diagnosis of scleredema and smolde...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt KT,Gattuso P,Messmore H,Shrit MA,Massa M,Welykyj S

更新日期：1992-02-01 00:00:00

abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...

journal_title：Journal of the American Academy of Dermatology

authors： de Groot AC,Weyland JW

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Malignant melanomas occur with increased frequency and at an early age in patients with xeroderma pigmentosum (XP). OBJECTIVE:The purpose of this study was to describe the histologic features of malignant melanomas in patients with XP and to search for a possible precursor lesion. METHODS:Clinical records ...

journal_title：Journal of the American Academy of Dermatology

authors： Stern JB,Peck GL,Haupt HM,Hollingsworth HC,Beckerman T

更新日期：1993-04-01 00:00:00