Effect of environmental alcohol on in vivo properties of Drosophila alcohol dehydrogenase.

Abstract:

:The effects of environmental 2-propanol on the in vivo properties of Drosophila alcohol dehydrogenase (E.C. 1..1.1.1.) are presented. Exposed flies were found to exhibit a significant decrease in ADH specific activity with a concomitant increase in the enzyme's relative in vivo stability and concentration. The possible adaptive significance of the observed responses is discussed.

journal_name

Biochem Genet

journal_title

Biochemical genetics

authors

Anderson SM,McDonald JF

doi

10.1007/BF00504285

subject

Has Abstract

pub_date

1981-04-01 00:00:00

pages

421-30

issue

3-4

eissn

0006-2928

issn

1573-4927

journal_volume

19

pub_type

杂志文章
  • Regulation of hemocytes in Drosophila requires dappled cytochrome b5.

    abstract::A major category of mutant hematopoietic phenotypes in Drosophila is melanotic tumors or nodules, which consist of abnormal and overproliferated blood cells, similar to granulomas. Our analyses of the melanotic mutant dappled have revealed a novel type of gene involved in blood cell regulation. The dappled gene is an ...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-010-9411-7

    authors: Kleinhesselink K,Conway C,Sholer D,Huang I,Kimbrell DA

    更新日期:2011-06-01 00:00:00

  • Association of Genetic Polymorphism in the Interleukin-8 Gene with Risk of Oral Cancer and Its Correlation with Pain.

    abstract::Oral cancer is a multifactorial disease process and involves complex interactions between gene to gene and gene to environmental factors. Interleukin 8 (IL-8), a pro-inflammatory cytokine, having angiogenic activity with elevated expression in tumor cells, is reported to play an essential role in oral cancer developme...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-015-9704-y

    authors: Singh PK,Chandra G,Bogra J,Gupta R,Kumar V,Hussain SR,Jain A,Mahdi AA,Ahmad MK

    更新日期:2016-02-01 00:00:00

  • Peptidase B polymorphism in cattle erythrocytes.

    abstract::Starch gel electrophoresis and histochemical staining with L-leucylglycyl-glycine revealed genetic polymorphism in peptidase B in cattle erythrocytes. Genetic analysis of 164 full families indicated that the three phenotypes observed are the product of an autosomal locus with two codominant alleles, PepB1 and PepB2. A...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:

    authors: Del Lama SN,Del Lama MA,Mestriner MA,Mortari N

    更新日期:1992-06-01 00:00:00

  • Molecular characterization and functional commonality of nucleophosmin/nucleoplasmin in two cyprinid fish.

    abstract::Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-009-9274-y

    authors: Wu N,Li CJ,Gui JF

    更新日期:2009-12-01 00:00:00

  • Allozyme variation and phylogenetic relationships in Picea jezoensis (Pinaceae) populations of the Russian Far East.

    abstract::Genetic variation and differentiation of 12 populations of Picea jezoensis from the Russian Far East were studied using 20 allozyme loci. The mean number of alleles per locus was 2.63, the percent of polymorphic loci was 88.1%, the observed heterozygosity was 0.181, and the mean value of expected heterozygosity amount...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-006-9075-5

    authors: Potenko VV

    更新日期:2007-04-01 00:00:00

  • Genetic control of chalcone isomerase activity in flowers of Dianthus caryophyllus.

    abstract::In flowers of Dianthus caryophyllus (carnation), the gene I is concerned with a discrete step in flavonoid biosynthesis, Genotypes with recessive (ii) alleles produce yellow flowers, which contain the chalcone isosalipurposide (naringenin-chalcone-2'-glucoside) as the major petal pigment, but in genotypes with wild-ty...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484399

    authors: Forkmann G,Dangelmayr B

    更新日期:1980-06-01 00:00:00

  • Interpopulation crosses, inheritance study, and genetic variability in the brown planthopper complex, Nilaparvata lugens (Homoptera: Delphacidae).

    abstract::Studies on hybridization, inheritance, and population genetics of brown planthoppers that infest rice and weeds were undertaken using starch gel electrophoresis to determine whether the weed-infesting population represents a biological race or a species. F(1) and F(2) generations were produced by crosses between paren...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-009-9316-5

    authors: Latif MA,Omar MY,Tan SG,Siraj SS,Ismail AR

    更新日期:2010-04-01 00:00:00

  • Parallel evolution of the glycogen synthase 1 (muscle) gene Gys1 between Old World and New World fruit bats (Order: Chiroptera).

    abstract::Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine wheth...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-014-9659-4

    authors: Fang L,Shen B,Irwin DM,Zhang S

    更新日期:2014-10-01 00:00:00

  • Qualitative changes in carboxylesterase-2 phenotypes of tetraploid loaches (Misgurnus fossilis L.).

    abstract::We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484449

    authors: Ivanenkov VV

    更新日期:1983-06-01 00:00:00

  • Immunological characterization of human acid phosphatase gene products.

    abstract::The immunological cross-reactivity of heterogeneous acid phosphatase isozymes from different human tissues has been studied using monospecific antisera prepared against four homogeneous acid phosphatases. The enzyme characterized as tartrate-inhibitable, prostatic acid phosphatase is also found to be present in leukoc...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00504327

    authors: Waheed A,Van Etten RL,Gieselmann V,von Figura K

    更新日期:1985-04-01 00:00:00

  • Gene duplication in salmonid fishes: evidence for duplicated but catalytically equivalent A4 lactate dehydrogenases.

    abstract::Skeletal muscle tissues from many species of salmonid fish are known to exhibit a set of three of five isozymes for A4-type lactate dehydrogenase (L-lactate: NAD oxidoreductase, E.C. 1.1.1.27), but the genetic basis for this isozyme system has not previously been assessed. This isozyme system was purified to homogenei...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484099

    authors: Lim ST,Bailey GS

    更新日期:1977-08-01 00:00:00

  • Gene topography and function. I. Gene expression in germinating conidia of Neurospora crassa.

    abstract::In an attempt to find clues for the significance of the gene ordering along the eukaryotic chromosome, a system consisting of germinating conida of Neurospora crassa was studied. Thirteen enzyme activities corresponding to genes widely distributed on five chromosomes were determined in dormant and in germinating conid...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484413

    authors: Jobbágy AJ,Aversa NO,Denoya CD

    更新日期:1975-12-01 00:00:00

  • Electrophoretic analysis of proteins from night-blind mutants of Phycomyces.

    abstract::Using two-dimensional gel electrophoresis, we have analyzed proteins from a plasma membrane-enriched fraction from Phycomyces sporangiophores. Specifically, we have compared gels for night-blind mutants and a wild-type strain to find proteins involved in the early steps of the sensory transduction chain for phototropi...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00499081

    authors: Pollock JA,Lipson ED,Sullivan DT

    更新日期:1985-06-01 00:00:00

  • Genetic mapping of the polycystic kidney gene, pcy, on mouse chromosome 9.

    abstract::The murine polycystic kidney disease gene, pcy, is an autosomal recessive trait located on chromosome 9. To determine the genetic locus of pcy, 222 intraspecific backcross mice were obtained by mating C57BL/6FG-pcy and Mus molossinus. Restriction fragment length polymorphism analysis of 70 of the 222 backcross progeny...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00554598

    authors: Nagao S,Watanabe T,Ogiso N,Marunouchi T,Takahashi H

    更新日期:1995-12-01 00:00:00

  • Heterogeneity in the molecular basis of three types of hereditary persistence of fetal hemoglobin and the relative synthesis of the G gamma and A gamma types of gamma chain.

    abstract::Restriction endonuclease analyses of DNA from one Black G gamma A gamma-HPFH homozygote and four Black and one Indian G gamma A gamma-HPFH heterozygotes have identified three different HPFH types which are the result of large deletions including the delta and beta genes. Two of the types are comparable to those charac...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00499284

    authors: Kutlar A,Gardiner MB,Headlee MG,Reese AL,Cleek MP,Nagle S,Sukumaran PK,Huisman TH

    更新日期:1984-02-01 00:00:00

  • Genetics of esterases in Drosophila. VI. Gene system regulating the phenotypic expression of the organ-specific esterase in Drosophila virilis.

    abstract::It is shown that the gene controlling the synthesis of the organ-specific S-esterase of Drosophila virilis ejaculatory bulbs is located on the second chromosome (at approximate position 192.1 +/- map units). The cells of the genital imaginal disks are determined for the synthesis of S-esterase 10-12 hr after the secon...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484728

    authors: Korochkin LI,Matveeva NM,Kuzin BA,Karasik GI,Maximovsky LF

    更新日期:1978-08-01 00:00:00

  • Genetic structure and variation of Van cats.

    abstract::To determine the genetic structure and variation of Van cats and some other cats, seven enzyme loci were examined using horizontal starch gel electrophoresis. ME bands were observed for the first time in cats. For the enzyme loci CA ( 1 ), SOD, GPI, and GOT, neither the individual Van cats nor the specimens of other c...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-011-9426-8

    authors: Altunok V,Yüksek N,Berkman CC,Ağaoğlu ZT,Togan I

    更新日期:2011-08-01 00:00:00

  • Genetic and endocrine control of renin activity in the submaxillary gland of the mouse.

    abstract::Basal activity of submaxillary gland (SMG) renin is high in female mice that carry the Rnrs allele and is induced to higher levels by treatment with dihydrotestosterone (DHT). To determine whether the difference in basal activity between high (Rnrs/Rnrs) and low (Rnrb/Rnrb) strains is due to enhanced sensitivity of Rn...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484623

    authors: Wilson CM,Cherry M,Taylor BA,Wilson JD

    更新日期:1981-06-01 00:00:00

  • Variation between electrophoretically identical alleles at the alcohol dehydrogenase locus in Drosophila melanogaster.

    abstract::A new variant of alcohol dehydrogenase (ADH 7lk) was found in a laboratory stock of Drosophila melanogaster. ADH in this stock had the same electrophoretic mobility as the F variant both on acrylamide and on agar. Activity levels were similar to the levels in F flies at temperature between 15 and 25 C. But while ADH F...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484929

    authors: Thörig EW,Schoone AA,Scharloo W

    更新日期:1975-10-01 00:00:00

  • Apolipoprotein E polymorphism in sheep.

    abstract::Using polyacrylamide gel isoelectric focusing followed by immunoblotting with anti-human apolipoprotein E (APO E) antibody, the genetic polymorphism of APO E was determined from desialylated plasma of 554 unrelated adults of four European sheep (Suffolk, Corriedale, Cheviot, and Finnish Landrace) and five Asian local ...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1023/a:1018753714783

    authors: Tsunoda K,Yamamoto Y,Akiya Y,Sato K,Rajbhandary HB,van Son H,Loc CB

    更新日期:1998-12-01 00:00:00

  • Arylsulfatase A activity and electrophoretic banding patterns from isolated human blood fractions.

    abstract::Arylsulfatase A (ASA) activity was studied from five blood fractions, leukocytes plus platelets (LKPL), leukocytes (LK), neutrophils (N), lymphocytes (LYM), and platelets (PL). No significant difference was found among the mean ASA specific activity values for the fractions. Electrophoretic examination revealed four d...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484068

    authors: Georgopoulos DE,Manowitz P

    更新日期:1982-10-01 00:00:00

  • A null mutation at the mouse Phosphoglucomutase-1 locus and a new locus Pgm-3.

    abstract::A null mutation at the phosphoglucomutase locus (Pgm-1) was discovered by electrophoretic analysis of the inbred mouse strain C57BL/6J. The null allele (Pgm-1n) was shown to segregate as a Mendelian unit alternative to the Pgm-1a and Pgm-1b alleles. Mice expressing the Pgm-1n allele, either in the heterozygous or homo...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484629

    authors: Johnson FM,Hendren RW,Chasalow F,Barnett LB,Lewis SE

    更新日期:1981-06-01 00:00:00

  • Identification of a locus modifying the electrophoretic mobility of malate dehydrogenase isozymes in incense-cedar (Calocedrus decurrens), and its implications for population studies.

    abstract::Using megagametophyte (maternal haploid) and embryo (diploid) tissues of incense-cedar seeds, the expression of one of three malate dehydrogenase (MDH) loci was found to be influenced by a second, unlinked, modifier locus. Whereas alleles of the affected structural locus are codominant, the modifier alleles show domin...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484435

    authors: Harry DE

    更新日期:1983-06-01 00:00:00

  • Genetic Diversity and Population Structure in Upland Rice (Oryza sativa L.) of Mizoram, North East India as Revealed by Morphological, Biochemical and Molecular Markers.

    abstract::Upland rice landraces from different villages of Mizoram, Northeast India were analyzed for seed morphology, amylose content, aromatic characteristic, seed storage protein profiling and genetic diversity. Results revealed variation in grain length, width, weight and shape. Protein profiling showed polypeptide bands ra...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-018-09901-1

    authors: Vanlalsanga,Singh YT

    更新日期:2019-06-01 00:00:00

  • The Effect of Pleistocene Climate Fluctuations on Distribution of European Abalone (Haliotis tuberculata), Revealed by Combined Mitochondrial and Nuclear Marker Analyses.

    abstract::The genetic differentiation among the populations of the European abalone Haliotis tuberculata was investigated using different markers to better understand the evolutionary history and exchanges between populations. Three markers were used: mitochondrial cytochrome oxidase I (COI), the sperm lysin nuclear gene, and e...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-016-9778-1

    authors: Roussel V,Van Wormhoudt A

    更新日期:2017-04-01 00:00:00

  • Association of Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor gamma 2 (PPARγ2) Gene with Type 2 Diabetes Mellitus in Ethnic Kashmiri Population.

    abstract::Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia associated with insulin resistance and relative insulin deficiency. T2DM is believed to be attributable to the combined effect of genetic and environmental factors. Peroxisome proliferator-activated receptor gamma 2 (PPARγ2) is one of the main c...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-016-9765-6

    authors: Majid M,Masood A,Kadla SA,Hameed I,Ganai BA

    更新日期:2017-02-01 00:00:00

  • Purine nucleoside phosphorylase polymorphism in the genus Littorina (Prosobranchia: Mollusca).

    abstract::Examination of eight Atlantic species of the genus Littorina by starch gel electrophoresis of purine nucleoside phosphorylase revealed extensive polymorphism within the L. saxatilis complex. In this group, four alleles have been identified. Heterozygotes are four banded, and thus, as in vertebrates, the enzyme is like...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00499096

    authors: Knight AJ,Ward RD

    更新日期:1986-06-01 00:00:00

  • Deleterious pleiotropic effects of the atypical aldehyde dehydrogenase 2 (ALDH2) allele: comment on Luo et al., 2005.

    abstract::Luo [Biochem. Genet. 43:223-227] concluded, "The mutation ALDH2(() 487Lys allele is not deleterious but is of great benefit to human health." This statement is easily subject to misinterpretation and needs to be clarified. Their results actually show there is a pleiotropic effect associated with the mutation ALDH2(() ...

    journal_title:Biochemical genetics

    pub_type: 评论,杂志文章

    doi:10.1007/s10528-006-9041-2

    authors: Sinclair D

    更新日期:2006-10-01 00:00:00

  • Assignment of a gene for tryptophanyl-transfer ribonucleic acid synthetase (E.C. 6.1.1.2) to human chromosome 14.

    abstract::We describe a simple method for locating tryptophanyl-tRNA synthetase (E.C. 6.1.1.2) on cellulose acetate gels (Cellogel) following electrophoresis. Employing electrophoretic conditions which result in the separation of mouse and human tryptophanyl-tRNA synthetase, we have analyzed extracts of a number of independentl...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/BF00484877

    authors: Denney RM,Craig IW

    更新日期:1976-02-01 00:00:00

  • Glacial effects on sequence divergence of mitochondrial COII of Polyura eudamippus (Lepidoptera: Nymphalidae) in China.

    abstract::Sequence divergence of mitochondrial COII was analyzed in 50 specimens belonging to five subspecies of Polyura eudamippus (Lepidoptera: Nymphalidae) collected from southern China. There were nine haplotypes in the 405 bp of partial COII sequence. Distribution of the five subspecies was primarily consistent with the sp...

    journal_title:Biochemical genetics

    pub_type: 杂志文章

    doi:10.1007/s10528-006-9035-0

    authors: Long Y,Wan H,Yan F,Xu C,Lei G,Li S,Wang R

    更新日期:2006-10-01 00:00:00