Myelin sheath thickness in the CNS is regulated near the axon.

Abstract:

:Two myelin sheaths sharing a common outer tongue process are illustrated in a thin section electron micrograph from mouse optic nerve. Although they derive from the same outer tongue process, and therefore from the same oligodendrocyte, the two sheaths are of different thicknesses (6 and 9 turns). The example demonstrates that myelin sheath thickness is regulated independently for each axon, at a site very near the axon.

journal_name

Brain Res

journal_title

Brain research

authors

Friedrich VL Jr,Mugnaini E

doi

10.1016/0006-8993(83)90712-6

subject

Has Abstract

pub_date

1983-09-12 00:00:00

pages

329-31

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(83)90712-6

journal_volume

274

pub_type

杂志文章
  • Effects of estrogen on potassium-stimulated acetylcholine release in the hippocampus and overlying cortex of adult rats.

    abstract::In vivo microdialysis techniques were used to examine the effects of estrogen on potassium-stimulated acetylcholine release in the hippocampus and overlying cortex of adult, ovariectomized rats. Estrogen treatment resulted in a significant increase in the percent change in acetylcholine release induced by potassium re...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(96)01375-3

    authors: Gibbs RB,Hashash A,Johnson DA

    更新日期:1997-02-21 00:00:00

  • The effect of the volatile anesthetic isoflurane on Ca(2+)-dependent glutamate release from rat cerebral cortex.

    abstract::A major effect of volatile anesthetics is to reduce excitatory synaptic transmission. In the present study the stimulated release of glutamate under the influence of increasing concentrations of isoflurane was studied in vitro by utilizing hippocampal slices from Wistar rats. Ca(2+)-dependent release was calculated by...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91282-3

    authors: Larsen M,Grøndahl TO,Haugstad TS,Langmoen IA

    更新日期:1994-11-14 00:00:00

  • GABA- and glycine-induced Cl- channels in cultured mouse spinal neurons require the same energy to close.

    abstract::Fluctuation analysis has been used to study the influence of temperature on the conductance and mean open time of Cl- permeable ion channels induced by gamma-aminobutyric acid (GABA) and glycine in the membrane of tissue cultured mouse spinal neurons. The conductance of GABA- and glycine-activated channels increased s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90875-1

    authors: Mathers DA,Barker JL

    更新日期:1981-11-16 00:00:00

  • Descending serotonergic, peptidergic and cholinergic pathways from the raphe nuclei: a multiple transmitter complex.

    abstract::The localization of serotonergic, various peptidergic and possibly cholinergic neurons in the medullary raphe nuclei that project to the lumbosacral spinal cord have been studied using a retrograde transport method combined with immunocytochemical and histochemical techniques. Spinally projecting neurons stained for s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90079-3

    authors: Bowker RM,Westlund KN,Sullivan MC,Wilber JF,Coulter JD

    更新日期:1983-12-12 00:00:00

  • Involvement of peripheral opioid receptors in electroacupuncture analgesia for carrageenan-induced hyperalgesia.

    abstract::Acupuncture is widely used to relieve pain; however, the mechanism underlying electroacupuncture analgesia (EAA) during inflammatory pain is unclear. We investigated whether endogenous peripheral opioid receptors participated in EAA during hyperalgesia elicited by carrageenan-induced inflammation. Moreover, we investi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.08.014

    authors: Taguchi R,Taguchi T,Kitakoji H

    更新日期:2010-10-08 00:00:00

  • Differential distribution of cellular forms of beta-amyloid precursor protein in murine glial cell cultures.

    abstract::The production and localization of cell-associated forms of beta-amyloid precursor protein (APP) of Alzheimer's disease was investigated in primary cultures of mouse glial cells. In both oligodendrocytes and astrocytes, immunofluorescence staining with an antibody against the carboxy terminus of APP revealed an intens...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90898-j

    authors: Mizuguchi M,Ikeda K,Kim SU

    更新日期:1992-07-03 00:00:00

  • Inhibition of the soleus H-reflex in standing man.

    abstract::There exists evidence to support the notion that the segmental reflex system is not fixed and inflexible, but rather is highly modifiable under a variety of circumstances. In this study the H-wave and M-wave recruitment curves were obtained from 19 subjects, utilizing the procedures outlined by Hugon. Each subject was...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90495-9

    authors: Koceja DM,Trimble MH,Earles DR

    更新日期:1993-11-26 00:00:00

  • Cortical field potentials preceding vocalization and influences of cerebellar hemispherectomy upon them in monkeys.

    abstract::Field potentials preceding vocalization were recorded with electrodes chronically implanted on the surface and at 2.0-3.0 mm depth in various cortical areas in three monkeys. Surface-negative, depth-positive (s-N, d-P) slow potentials prior to vocalization were recorded in the premotor (including the Broca's homology)...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00797-t

    authors: Gemba H,Miki N,Sasaki K

    更新日期:1995-10-30 00:00:00

  • Late-phase recovery in the cochlear lateral wall following severe degeneration by acute energy failure.

    abstract::We previously reported a model of acute cochlear energy failure using a mitochondrial toxin, 3-nitropropionic acid (3-NP), to study mechanisms of inner ear disorders such as inner ear ischemia. In this model, the main cause of hearing loss is apoptosis of fibrocytes in the cochlear lateral wall. Here, we analyzed the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.08.062

    authors: Mizutari K,Nakagawa S,Mutai H,Fujii M,Ogawa K,Matsunaga T

    更新日期:2011-10-24 00:00:00

  • Altered expression levels of G protein subclass mRNAs in various seizure stages of the kindling model.

    abstract::The expressions of mRNAs encoding G protein alpha subunits were analyzed in the cerebral cortex of amygdaloid kindled rats. A remarkable increase in Gsalpha mRNA were observed on the bilateral cerebral cortex at 24 h after the last generalized seizure and persisted 3 weeks on the unstimulated side. Gi2alpha mRNA level...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)01309-2

    authors: Iwasa H,Kikuchi S,Miyagishima H,Mine S,Koseki K,Hasegawa S

    更新日期:1999-02-13 00:00:00

  • Effects of combined or separate 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei on responding maintained by a DRL 20s schedule of food reinforcement.

    abstract::Previous studies have shown that long-term 5-hydroxytryptamine (5-HT) depletion induced by combined dorsal and median raphe injections of 5,7-dihydroxytryptamine (5,7-DHT) leads to impairments in the acquisition and performance of behaviour maintained under a differential-reinforcement-of-low-rate (DRL) schedule of re...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00037-q

    authors: Fletcher PJ

    更新日期:1995-03-27 00:00:00

  • Protein kinase C isozyme expression in sciatic nerves and spinal cords of experimentally diabetic rats.

    abstract::Changes in the expression and activation of protein kinase C (PKC) have been implicated in the pathogenesis of diabetic neuropathy. Recent studies in liver, retina, and cardiovascular tissues from experimentally diabetic rats have demonstrated that diabetes has a selective effect on the expression and subcellular dist...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00062-0

    authors: Roberts RE,McLean WG

    更新日期:1997-04-18 00:00:00

  • Whither motoneurons?

    abstract::In the preceding series of articles, the history of vertebrate motoneuron and motor unit neurobiological studies has been discussed. In this article, we select a few examples of recent advances in neuroscience and discuss their application or potential application to the study of motoneurons and the control of movemen...

    journal_title:Brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.brainres.2011.06.008

    authors: Brownstone RM,Stuart DG

    更新日期:2011-08-29 00:00:00

  • Adenosine depresses induction of LTP at the mossy fiber-CA3 synapse in vitro.

    abstract::Using the hippocampal slice preparation, extracellular recordings of CA3 field excitatory postsynaptic potentials (fEPSPs) were performed to assess the effects of adenosine on the induction of mossy fiber long-term potentiation (LTP). When present during tetanization, adenosine (50 microM) significantly suppressed mos...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91061-5

    authors: Alzheimer C,Röhrenbeck J,ten Bruggencate G

    更新日期:1991-03-08 00:00:00

  • The role of norepinephrine in mediating luteinizing hormone release in response to blockade of kappa-opioid receptors in the medial preoptic area.

    abstract::Our previous study [32] indicated that blockade of kappa-opioid receptors with nor-binaltorphimine (nor-BNI) in the medial preoptic area (MPOA) produced two different LH responses during midpregnancy in the rat: an increase in basal pulsatile LH secretion, followed in many cases by a larger and/or sustained increase i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00874-p

    authors: Zhen S,Gallo RV

    更新日期:1995-11-06 00:00:00

  • Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice.

    abstract::The pathological process in Alzheimer's disease (AD) involves amyloid beta (Abeta) deposition and neuronal cell degeneration. The neurotoxic Abeta peptide is derived from the amyloid precursor protein (APP), a member of a larger gene family including the amyloid precursor-like proteins, APLP1 and APLP2. The APP and AP...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01861-2

    authors: White AR,Reyes R,Mercer JF,Camakaris J,Zheng H,Bush AI,Multhaup G,Beyreuther K,Masters CL,Cappai R

    更新日期:1999-09-25 00:00:00

  • Alpha motoneuron responses to natural stimuli in decerebellate cats.

    abstract::The responses of single alpha motoneurons to various "natural' stimuli were recorded from dissected ventral root filaments in lightly anesthetized control and recently decerebellate cats. The identity of the motoneurons was established by recording the unitary responses to orthodromic stimulation of nerves innervating...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(75)90208-5

    authors: Copack PB,Lieberman JS,Gilman S

    更新日期:1975-09-12 00:00:00

  • Increased GABA binding in mouse brain following acute swim stress.

    abstract::Acute swim stress of mice produces increases in the density of high and low affinity binding sites in the brain for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), together with analgesia as measured by an increase in tail flick latency. Apparent tolerance develops in repeated swimming with analgesia a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90524-2

    authors: Skerritt JH,Trisdikoon P,Johnston GA

    更新日期:1981-06-29 00:00:00

  • Comparison of the immunocytochemical distribution of the phosphoprotein B-50 in the cerebellum and hippocampus of immature and adult rat brain.

    abstract::In this study we compare the distribution of the phosphoprotein B-50 in two regions of immature and adult rat brain using affinity-purified antibodies to B-50. In the cerebellum of the 8-day-old rat we observed distinct patterns of distribution of B-50 immunoreactivity (BIR) in the premigratory zone and the developing...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90747-x

    authors: Oestreicher AB,Gispen WH

    更新日期:1986-06-11 00:00:00

  • Stress enhances electrical synapse formation between regenerating neurons.

    abstract::A pair of adult molluscan neurons (L5 and R5) are known to sprout and form a new electrical synapse following axotomy. Additionally, certain forms of stress can elicit restricted sprouting of neurons L5 and R5 within the intact nervous system. This study found that the strength of 5-5 electrical coupling was increased...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90759-0

    authors: Bulloch AG

    更新日期:1985-09-23 00:00:00

  • The effect of activated microglia on astrogliosis parameters in astrocyte cultures.

    abstract::In the diseased central nervous system, astrogliosis is accompanied by microglial activation. Depending on the context of their activation, reactive astrocytes are involved in neuronal survival and regeneration in an either protective or impedimental way. Major reactive changes of astrocytes in vivo are the upregulati...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.10.057

    authors: Röhl C,Lucius R,Sievers J

    更新日期:2007-01-19 00:00:00

  • Effects of NMDA receptor blockade and nitric oxide synthase inhibition on the acute and chronic actions of delta 9-tetrahydrocannabinol in mice.

    abstract::The present studies examined the hypothesis that the N-methyl-D-aspartate (NMDA) receptor-nitric oxide (NO) pathway might be involved in the acute and chronic actions of delta 9-tetrahydrocannabinol (THC). The ability of dizocilpine (MK-801), a competitive NMDA receptor antagonist and NG-monomethyl-L-arginine (L-NMMA)...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91715-9

    authors: Thorat SN,Bhargava HN

    更新日期:1994-12-19 00:00:00

  • Decreased rat brain cytochrome oxidase activity after prolonged hypoxia.

    abstract::Three weeks of hypoxic exposure results in a spectrum of systemic physiological and local brain tissue adaptations. Cytochrome oxidase histochemistry was used as an indicator of changes in energy demand in response to hypoxia. We found overall cytochrome oxidase activity decreased in hypoxic adapted rats as compared t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01495-0

    authors: LaManna JC,Kutina-Nelson KL,Hritz MA,Huang Z,Wong-Riley MT

    更新日期:1996-05-13 00:00:00

  • Muramyl dipeptide potentiates cytokine-induced activation of inducible nitric oxide synthase in rat astrocytes.

    abstract::We investigated the influence of muramyl dipeptide (MDP), a cell wall component of Gram-positive bacteria, on cytokine-induced nitric oxide (NO) production in rat primary astrocytes. MDP alone did not induce NO release in astrocyte cultures. However, MDP increased astrocyte NO production and subsequent nitrite accumul...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02920-6

    authors: Trajkovic V,Samardzic T,Stosic-Grujicic S,Ramic Z,Mostarica Stojkovic M

    更新日期:2000-11-10 00:00:00

  • Neural correlates of pair-bonding in a monogamous primate.

    abstract::The neurobiology of social bonding, despite its relevance to human mental health, has been studied primarily in rodents. In this study we used position emission tomography (PET), registered with structural magnetic resonance imaging (MRI) to investigate central glucose uptake in 17 males of a monogamous primate specie...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.09.087

    authors: Bales KL,Mason WA,Catana C,Cherry SR,Mendoza SP

    更新日期:2007-12-12 00:00:00

  • Loss and displacement of ganglion cells after optic nerve regeneration in adult Rana pipiens.

    abstract::After studying pathway selection in the brain of Rana pipiens during unilateral optic nerve regeneration, several frogs were allowed to survive for lengthy periods for use in the present investigation. Retina flat-mounts were prepared from both eyes at 42-50 weeks postoperation. In some cases, HRP was infiltrated into...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90804-2

    authors: Scalia F,Arango V,Singman EL

    更新日期:1985-10-07 00:00:00

  • The effect of nerve stump length upon mammalian taste responses.

    abstract::A decline in the magnitude of the summated responses evoked by taste solutions began about 1 h following IXth nerve transection. In 41 IXth nerves transected at different lengths we found a linear relationship between the length of the IXth nerve stump remaining attached to the tongue and the time for the taste respon...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)91331-1

    authors: Oakley B,Jones LB,Hosley MA

    更新日期:1980-07-21 00:00:00

  • Taurine transport at the blood-brain barrier: an in vivo brain perfusion study.

    abstract::Taurine transport into six brain regions of equithesin-anesthetized rats was studied by the in situ brain perfusion technique. This technique gives both accurate measurements of cerebrovascular amino acid transport and allows complete control of the perfusate amino acid composition. Final wash procedure showed that ta...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00648-a

    authors: Benrabh H,Bourre JM,Lefauconnier JM

    更新日期:1995-09-18 00:00:00

  • Regional localization of agmatine in the rat brain: an immunocytochemical study.

    abstract::The distribution of agmatine (decarboxylated arginine) was mapped in the central nervous system (CNS) in the rat. Agmatine-like immunoreactivity was identified by light microscopy, exclusively in the cytoplasm of neuronal perikarya. Immunoreactive neurons were present in the cerebral cortex, predominantly within lamin...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01200-6

    authors: Otake K,Ruggiero DA,Regunathan S,Wang H,Milner TA,Reis DJ

    更新日期:1998-03-16 00:00:00

  • Retrograde axonal transport of horseradish peroxidase for determining motor projection patterns to the developing limb in Xenopus.

    abstract::Horseradish peroxidase (HRP) injected into developing limb buds of Xenopus laevis tadpoles is carried by retrograde axonal transport to the somata of motoneurones in the ventral horn. Small injection of 10% HRP were found to remain well localised to specified sites in the limb bud. Two types of labelled cells were fou...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(77)91067-8

    authors: Lamb AH

    更新日期:1977-10-07 00:00:00