Accumulation of furanic labdane diterpenes in Marrubium vulgare and Leonurus cardiaca.

abstract：:Micellar electrokinetic capillary chromatography (MECC), using a phosphate buffer pH 7.0 and sodium dodecyl sulfate as the surfactant, was found suitable for the separation of structurally similar flavan-3-ols and related dimeric proanthocyanidins. A total of 20 substances has been tested, 17 of which were successfull...

journal_title：Planta medica

authors： Kreimeyer J,Petereit F,Nahrstedt A

更新日期：1998-02-01 00:00:00

abstract：:The antimycobacterial quinolones 1-methyl-2-undecyl-4-quinolone, dihydroevocarpine and evocarpine as well as the indoloquinazoline alkaloids rutaecarpine and evodiamine - all from the Chinese medicinal herb Evodia rutaecarpa - were tested in two in vitro assays, for cytotoxicity and interaction with p-glycoprotein (p-...

journal_title：Planta medica

authors： Adams M,Mahringer A,Kunert O,Fricker G,Efferth T,Bauer R

更新日期：2007-12-01 00:00:00

abstract：:A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the ef...

journal_title：Planta medica

authors： El-Dakhakhny M,Mady N,Lembert N,Ammon HP

更新日期：2002-05-01 00:00:00

abstract：:The therapeutic goal in liver fibrosis is the reversal of fibrosis and the selective clearance of activated hepatic stellate cells (HSCs) by inducing apoptosis. Over the past several years, we have screened for natural products that mediate apoptosis in activated HSCs. Among the candidate compounds, honokiol, isolated...

journal_title：Planta medica

authors： Park EJ,Zhao YZ,Kim YH,Lee BH,Sohn DH

更新日期：2005-01-01 00:00:00

abstract：:Tryptanthrin and (E,Z)-3-(4-hydroxy-3,5-dimethoxybenzylidene)indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-inflammatory and antiallergic alkaloids, and shown to inhibit COX-2, 5-LOX catalyzed leukotriene synthesis, and mast cell degranulation at low µM to nM concentrations. To ass...

journal_title：Planta medica

authors： Jähne EA,Eigenmann DE,Moradi-Afrapoli F,Verjee S,Butterweck V,Hebeisen S,Hettich T,Schlotterbeck G,Smieško M,Hamburger M,Oufir M

更新日期：2016-08-01 00:00:00

abstract：:The 80% and 70% acetone extracts from fruits and leaves of Crataegus sinaica Boiss (Rosaceae) and the ethyl acetate-, butanol-, and water-fractions obtained from these initial extracts as well as the isolated compounds, quercetin (1) (1), hyperoside (quercetin 3-O-galactoside) (2) (2), rutin (quercetin 3-O-rutinoside)...

journal_title：Planta medica

authors： Shahat AA,Hammouda F,Ismail SI,Azzam SA,De Bruyne T,Lasure A,Van Poel B,Pieters L,Vlietinck AJ

更新日期：1996-02-01 00:00:00

abstract：:The species Ageratina pichinchensis (Asteraceae) has been used for a long time in Mexican traditional medicine for the treatment of different skin conditions and injuries. In this study, the healing capacity of the plant extracts obtained was evaluated and, in order to understand the mechanism of healing, we also anal...

journal_title：Planta medica

authors： Romero-Cerecero O,Zamilpa-Álvarez A,Ramos-Mora A,Alonso-Cortés D,Jiménez-Ferrer JE,Huerta-Reyes ME,Tortoriello J

更新日期：2011-07-01 00:00:00

abstract：:We previously reported that total coumarins, the major active components of Urtica dentata Hand, exhibited substantial protection against the development of autoimmune diabetes. Diabetic nephropathy is one of the most serious complications of diabetes and is closely correlated with end-stage renal disease. We used the...

journal_title：Planta medica

authors： Cao H,Ji Y,Li W,Liu Y,Fu R,Xiang M

更新日期：2015-10-01 00:00:00

abstract：:Three new dammar-type triterpenoid caffeates (1-3) were isolated from the stalks of Celastrus rosthornianus Loes. Their structures were established through various spectral studies as 3beta,20(S),24(S)-trihydroxyldammar-25-ene 3-caffeate (1), 3beta,20(S),24(R)-trihydroxyldammar-25-ene 3-caffeate (2) and 3beta,20(S),25...

journal_title：Planta medica

authors： Wang KW,Sun CR,Wu XD,Pan YJ

更新日期：2006-03-01 00:00:00

abstract：:Five new xanthone glycosides, comastomasides A-E (1-5), were isolated from aqueous ethanol extracts of the aerial portions of Comastoma pedunculatum. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-5 were evaluated for their hepatoprotective activity and cytotoxicity ag...

journal_title：Planta medica

authors： Qiao Y,Yuan Y,Cui B,Zhang Y,Chen H,Li S,Li Y

更新日期：2012-09-01 00:00:00

abstract：:Valeriana officinalis L. is a popular herbal treatment for mild sleep disorders. Clinical and non-clinical studies found contradictory results for valerian extracts and single constituents regarding the influence on sleep parameters. It was the aim of this study to investigate the sedative effects of a valerian root e...

journal_title：Planta medica

authors： Chow NK,Fretz M,Hamburger M,Butterweck V

更新日期：2011-05-01 00:00:00

abstract：:From stem barks of Isolona guesquiereina three known bisbenzylisoquinolines were isolated and identified as (-)-curine, chondrofoline and isochondodendrine. Structures were established mainly on the basis of comparison of their physical and spectral data with published data for them and their methylated derivatives. C...

journal_title：Planta medica

authors： Mambu L,Martin MT,Razafimahefa D,Ramanitrahasimbola D,Rasoanaivo P,Frappier F

更新日期：2000-08-01 00:00:00

abstract：:Tissue callus cultures originating from CHELIDONIUM MAJUS L. seeds were established on Gamborg B5, Murashige-Skoog (MS), and Schenk-Hildebrandt (SH) media. In all experimental conditions, calli accumulated a complex pattern of isoquinoline derivatives. The highest values, both in growth and in sanguinarine production,...

journal_title：Planta medica

authors： Colombo ML,Tomé F

更新日期：1991-10-01 00:00:00

abstract：:The major alkaloids of PAPAVER TRINIIFOLIUM collected in two different parts of Anatolia have proved to be of the aporphine, morphinane and rhoeadine types. The two collections possessed different major alkaloids and the existence of chemical strains is indicated. In addition to the aporphine-(floripavidine), the morp...

journal_title：Planta medica

authors： Sariyar G

更新日期：1983-09-01 00:00:00

abstract：:Effects of puerarin, an active principle contained in the roots of Pueraria lobata (Leguminosae), on the regulation of glucose metabolism in an insulin deficient state were investigated in cultured myoblast C 2 C 12 cells using glucose uptake as indicator. Puerarin enhanced the uptake of radioactive glucose into C 2 C...

journal_title：Planta medica

authors： Hsu HH,Chang CK,Su HC,Liu IM,Cheng JT

更新日期：2002-11-01 00:00:00

abstract：:25 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell lines (Molt4 and HepG2) according to established protocols. Significant differences of activity related with the type of skeleton of t...

journal_title：Planta medica

authors： Weniger B,Italiano L,Beck JP,Bastida J,Bergoñon S,Codina C,Lobstein A,Anton R

更新日期：1995-02-01 00:00:00

abstract：:Pure compounds were isolated from plant extracts with antimalarial activity. The extracts were obtained from the tubers of Cyperus rotundus L. (Cyperaceae), the rootbark of Zanthoxylum gilletii (De Wild) Waterm. (Rutaceae), and the rootbark of Margaritaria discoidea (Baill.) Webster (Euphorbiaceae). The most active co...

journal_title：Planta medica

authors： Weenen H,Nkunya MH,Bray DH,Mwasumbi LB,Kinabo LS,Kilimali VA,Wijnberg JB

更新日期：1990-08-01 00:00:00

abstract：:Based on the inhibition of Cu(2+)-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol. Sesamin and fargesin...

journal_title：Planta medica

authors： Chen CC,Chen HY,Shiao MS,Lin YL,Kuo YH,Ou JC

更新日期：1999-12-01 00:00:00

abstract：:Croton caudatus is an important species in Dai folk medicine. Some other Croton species, in particular, C. kongensis, C. cascarilloides, C. crassifolius, C. lachnocarpus and C. olivaceus are often marketed as C. caudatus, and thus, the therapeutic effects of C. caudatus are not achieved. The respective morphological f...

journal_title：Planta medica

authors： Xue HG,Zhou SD,He XJ,Yu Y

更新日期：2007-06-01 00:00:00

abstract：:Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of Enicostemma axillare, was evaluated for antiedematogenic activity using carrageenan-, formalin-, and histamine-induced paw edema methods in rats. In the carrageenan-induced method, the percentages of edema inhibition obtained after 5 h induction we...

journal_title：Planta medica

authors： Vaijanathappa J,Badami S

更新日期：2009-01-01 00:00:00

abstract：:Cordatolide A and B were re-isolated from Calophyllum cordato-oblongum, an endemic species of Sri Lanka, and found to inhibit HIV-1 reverse transcriptase with IC50 values of 12.3 and 19.0 microM, respectively. ...

journal_title：Planta medica

authors： Dharmaratne HR,Wanigasekera WM,Mata-Greenwood E,Pezzuto JM

更新日期：1998-06-01 00:00:00

abstract：:The inhibition of aflatoxin B1 (AFB1) metabolism by a water extract of the root of Scutellaria baicalensis and its flavonoids was examined in liver microsomes. AFB1 is known to be metabolized to aflatoxin M1 (AFM1), aflatoxin Q1 (AFQ1), and AFB1-8,9-epoxide (AFBO). The water extract potently inhibited the production o...

journal_title：Planta medica

authors： Kim BR,Kim DH,Park R,Kwon KB,Ryu DG,Kim YC,Kim NY,Jeong S,Kang BK,Kim KS

更新日期：2001-07-01 00:00:00

abstract：:Because Rhodiola plants are known to have a protective effect on diabetic nephropathy, this study aimed to investigate the inhibitory effect of salidroside, the main active component of Rhodiola plants, on high glucose-induced mesangial cell proliferation and its possible mechanism. Salidroside (1 approximately 100 mi...

journal_title：Planta medica

authors： Yin D,Yao W,Chen S,Hu R,Gao X

更新日期：2009-09-01 00:00:00

abstract：:Thirty-five flavonoids of seven different types, namely isoflavonoids, chalcones, dihydroflavonols, flavanols, flavanones, flavones, and flavonols were investigated for their ability to inhibit ascorbate-induced microsomal lipid peroxidation and their cytotoxicity. For each activity a structure-activity relationship w...

journal_title：Planta medica

authors： Cos P,Calomme M,Sindambiwe JB,De Bruyne T,Cimanga K,Pieters L,Vlietinck AJ,Vanden Berghe D

更新日期：2001-08-01 00:00:00

abstract：:The traditional analgesic and antipyretic Ethiopian drug "Dingetegna" is made of dried root material of Taverniera abyssinica A. Rich (Leguminosae). In a screening for nematicidal natural products, "Dingetegna" extracts showed strong nematicidal activities towards C. elegans. In the following, medicarpin and 4-hydroxy...

journal_title：Planta medica

authors： Stadler M,Dagne E,Anke H

更新日期：1994-12-01 00:00:00

abstract：:In our investigation of in vitro antimalarial screening of medicinal herbal extracts, the n-BuOH extract from the root of Wikstroemia indica showed a potent inhibitory effect. Fractionation of the active extract led to the isolation of two biflavonoids, sikokianin B ( 1) and sikokianin C ( 2) with IC (50) values 0.54 ...

journal_title：Planta medica

authors： Nunome S,Ishiyama A,Kobayashi M,Otoguro K,Kiyohara H,Yamada H,Omura S

更新日期：2004-01-01 00:00:00

abstract：:An efficient in vitro propagation protocol for rapidly producing Cannabis sativa plantlets from young leaf tissue was developed. Using gas chromatography-flame ionization detection (GC-FID), high THC yielding elite female clone of a drug-type CANNABIS variety (MX) was screened and its vegetatively propagated clones we...

journal_title：Planta medica

authors： Lata H,Chandra S,Khan IA,Elsohly MA

更新日期：2010-10-01 00:00:00

abstract：:Two new heliangolides, incomptines C (3) and D (4), were isolated from the leaves of Decachaeta incompta. The structures were established by spectroscopic methods and confirmed by X-ray crystallography. The antiprotozoal activity of incomptines C and D was evaluated. Additionally, the chromatographic profile of the le...

journal_title：Planta medica

authors： Bautista E,Calzada F,Yepez-Mulia L,Chavez-Soto M,Ortega A

更新日期：2012-10-01 00:00:00

abstract：:Menopause is characterized by deep metabolic disturbances, including decreased insulin sensitivity, adiposity, and changes in lipid profiles. Estrogen replacement therapy can partially reverse these changes, and while it is safe in most healthy postmenopausal women, there are still existing concerns regarding an incre...

journal_title：Planta medica

authors： Jeremic I,Petricevic S,Tadic V,Petrovic D,Tosic J,Stanojevic Z,Petronijevic M,Vidicevic S,Trajkovic V,Isakovic A

更新日期：2019-04-01 00:00:00

abstract：:Treatment of 28-hydroxyolean-12-enes with N-bromosuccinimide (NBS) in acetonitrile at room temperature afforded 12 alpha-bromooleanan-13beta, 28-epoxides in high yield. This reaction resulted in the formation of olean-9 (11), 12-diene-18alpha, 29-epoxides from 29-hydroxy isomers but recovered only starting materials f...

journal_title：Planta medica

authors： Woo WS,Kang SS,Jew SS

更新日期：1985-12-01 00:00:00