Separations of flavan-3-ols and dimeric proanthocyanidins by capillary electrophoresis.


:Micellar electrokinetic capillary chromatography (MECC), using a phosphate buffer pH 7.0 and sodium dodecyl sulfate as the surfactant, was found suitable for the separation of structurally similar flavan-3-ols and related dimeric proanthocyanidins. A total of 20 substances has been tested, 17 of which were successfully separated simultaneously in less than 7 minutes. Retention of the investigated compounds by the SDS micelles is affected by (i) the stereochemistry of the heterocycle of the flavan-3-ol skeleton, (ii) the molecular size, the number and position of free phenolic hydroxy groups, and (iii) the type of acyl residues attached at the C-3 hydroxy function. The method was successfully applied to the phytochemical analysis of tannin enriched extracts of Cistus incanus L. ssp. incanus and C. salvifolius L. (Cistaceae), two traditionally used medicinal plants.


Planta Med


Planta medica


Kreimeyer J,Petereit F,Nahrstedt A




Has Abstract


1998-02-01 00:00:00












  • Protective effect of Labisia pumila on stress-induced behavioral, biochemical, and immunological alterations.

    abstract::The aim of the present study was to investigate the antistress potential of LABISIA PUMILA aqueous extract (LPPM/A003) using a battery of tests widely employed in different stressful situations. Pretreatment of experimental animals with LPPM/A003 caused an increase in the swimming endurance and hypoxia time and also s...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Kour K,Sharma N,Chandan BK,Koul S,Sangwan PL,Bani S

    更新日期:2010-10-01 00:00:00

  • An in vitro Study on the Effect of Momordica charantia on Glucose Uptake and Glucose Metabolism in Rats.

    abstract::The effect of extracts of MOMORDICA CHARANTIA L. fruits on glucose metabolism and glucose uptake was investigated. The fruit of momordica, at all ripening stages, was found to contain two inhibitory compounds: one against hexokinase activity and the other against glucose uptake by rat intestinal fragments. Both inhibi...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Meir P,Yaniv Z

    更新日期:1985-02-01 00:00:00

  • Extraction Method and Analysis of Cannabinoids in Cannabis Olive Oil Preparations.

    abstract::Recently, an increasing number of pharmacists had to supply medicinal products based on Cannabis sativa L. (Cannabaceae), prescribed by physicians to individual patients. Cannabis olive oil preparation is the first choice as a concentrated extract of cannabinoids, even though standardized operative conditions for obta...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Casiraghi A,Roda G,Casagni E,Cristina C,Musazzi UM,Franzè S,Rocco P,Giuliani C,Fico G,Minghetti P,Gambaro V

    更新日期:2018-03-01 00:00:00

  • A beta-Hydroxychalcone from Leptospermum scoparium.

    abstract::A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Mayer R

    更新日期:1993-06-01 00:00:00

  • Arbuscular mycorrhizal inoculation enhances survival rates and growth of Micropropagated plantlets of Echinacea pallida.

    abstract::In an attempt to induce positive effects on the acclimatization of in vitro propagated Echinacea pallida, four arbuscular mycorrhizal (AM) fungi, Glomus mosseae, Gigaspora ramisporophora, Scutellospora fulgida and Entrophospora colombiana were selected to aid the soil adaptation process. Fungal inocula affected the su...

    journal_title:Planta medica

    pub_type: 信件


    authors: Lata H,De Andrade Z,Schaneberg B,Bedir E,Khan I,Moraes R

    更新日期:2003-07-01 00:00:00

  • Metabolic Profiling of Saponin-Rich Ophiopogon japonicus Roots Based on 1H NMR and HPTLC Platforms.

    abstract::Ideally, metabolomics should deal with all the metabolites that are found within cells and biological systems. The most common technologies for metabolomics include mass spectrometry, and in most cases, hyphenated to chromatographic separations (liquid chromatography- or gas chromatography-mass spectrometry) and nucle...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Ge Y,Chen X,Gođevac D,Bueno PCP,Salomé Abarca LF,Jang YP,Wang M,Choi YH

    更新日期:2019-08-01 00:00:00

  • Inhibitory activity of stilbenes from medicinal plants on the expression of cell adhesion molecules on THP1 cells.

    abstract::The inhibitory activity of stilbenes isolated from medicinal plants on cell adhesion molecules on the surface of THP-1 human monocytic cell lines was investigated. Among ten stilbenes tested, four stilbenes displayed a significant inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1)...

    journal_title:Planta medica

    pub_type: 信件


    authors: Ahn KS,Kim JH,Oh SR,Ryu SY,Lee HK

    更新日期:2000-10-01 00:00:00

  • Effects of Sideritis scardica Extract on Glucose Tolerance, Triglyceride Levels and Markers of Oxidative Stress in Ovariectomized Rats.

    abstract::Menopause is characterized by deep metabolic disturbances, including decreased insulin sensitivity, adiposity, and changes in lipid profiles. Estrogen replacement therapy can partially reverse these changes, and while it is safe in most healthy postmenopausal women, there are still existing concerns regarding an incre...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Jeremic I,Petricevic S,Tadic V,Petrovic D,Tosic J,Stanojevic Z,Petronijevic M,Vidicevic S,Trajkovic V,Isakovic A

    更新日期:2019-04-01 00:00:00

  • Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa.

    abstract::The antimycobacterial quinolones 1-methyl-2-undecyl-4-quinolone, dihydroevocarpine and evocarpine as well as the indoloquinazoline alkaloids rutaecarpine and evodiamine - all from the Chinese medicinal herb Evodia rutaecarpa - were tested in two in vitro assays, for cytotoxicity and interaction with p-glycoprotein (p-...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Adams M,Mahringer A,Kunert O,Fricker G,Efferth T,Bauer R

    更新日期:2007-12-01 00:00:00

  • Minor Iridoid and Phenol Glycosides of Picrorhiza kurrooa.

    abstract::From the roots of PICRORHIZA KURROOA a new iridoid glycoside, 6-feruloylcatalpol has been isolated, along with veronicoside and minecoside and two phenol glucosides, picein and androsin. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Stuppner H,Wagner H

    更新日期:1989-10-01 00:00:00

  • Inhibition of thrombin activity by selected natural products in comparison to neutrophil elastase.

    abstract::Enzymatic thrombin activity is significantly inhibited only by a few selected natural phenolic compounds (myricetin, rosmarinic acid, caffeic acid phenethyl ester) but more strongly by unsaturated fatty acids like erucic acid and oleic acids. Compared to the inhibitory potential against neutrophil elastase, thrombin a...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Melzig MF,Henke K

    更新日期:2005-08-01 00:00:00

  • Inhibition of human dendritic cell activation by hydroethanolic but not lipophilic extracts of turmeric (Curcuma longa).

    abstract::Turmeric has been extensively utilized in Indian and Chinese medicine for its immune-modulatory properties. Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and regulate immunity. The ability of DCs to initiate immunity is linked to their activation status. The effects of turmeric on human DC...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Krasovsky J,Chang DH,Deng G,Yeung S,Lee M,Leung PC,Cunningham-Rundles S,Cassileth B,Dhodapkar MV

    更新日期:2009-03-01 00:00:00

  • Neuroprotective effects in gerbils of spiramine T from Spiraea japonica var. acuta.

    abstract::The neuroprotective effects of spiramine T, an atisine-type diterpenoid alkaloid isolated from the Chinese herbal medicine Spiraea japonica var. acuta (Rosaceaee), on cerebral ischemia-reperfusion injury produced by 10-min bilateral occlusion of the common carotid arteries followed by 5-day reperfusion in gerbils were...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Li L,Nie J,Shen Z,Wu W,Chen Z,Hao X

    更新日期:2001-03-01 00:00:00

  • Plasma pharmacokinetics and tissue distribution of arctiin and its main metabolite in rats by HPLC-UV and LC-MS.

    abstract::The pharmacokinetic profile of arctiin, the major active lignan in fruits of Arctium lappa L., was investigated. Its main meta"bolite arctigenin was identified by an LC-MS method, and an HPLC-UV technique was developed for the simultaneous quantification of the metabolite and arctiin in plasma and organs. Chromatograp...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: He F,Dou DQ,Sun Y,Zhu L,Xiao HB,Kang TG

    更新日期:2012-05-01 00:00:00

  • Light-mediated antifungal activity of Echinacea extracts.

    abstract::This study demonstrated that plant extracts containing acetylenic isobutylamides and polyacetylenes, previously reported as occurring in Echinacea, have phototoxic antimicrobial activity against fungi, including clinically relevant pathogenic fungi. Results show that hexane extracts of Echinacea variably inhibit growt...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Binns SE,Purgina B,Bergeron C,Smith ML,Ball L,Baum BR,Arnason JT

    更新日期:2000-04-01 00:00:00

  • [Plants from new caledonia: alkaloids of stem-bark of Hernandia cordigera].

    abstract::The alkaloidal content of of the stem barks of Hernandia cordigera has been studied and compared to that of other Hernandia species. Main alkaloids are phenolic aporphines. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Lavault M,Debray MM,Bruneton J

    更新日期:1981-05-01 00:00:00

  • Inhibition of chemiluminescence in human PMNs by monocyclic phenolic acids and flavonoids.

    abstract::Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Limasset B,Ojasoo T,le Doucen C,Doré JC

    更新日期:1999-02-01 00:00:00

  • Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity.

    abstract::Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...

    journal_title:Planta medica

    pub_type: 杂志文章,评审


    authors: Potterat O

    更新日期:2010-01-01 00:00:00

  • Antitumor activity of PEGylated nanoliposomes containing crocin in mice bearing C26 colon carcinoma.

    abstract::Crocin is a pharmacologically active component of Crocus sativus. It is an unusual water-soluble carotenoid responsible for the red color of saffron. In various studies, the anticancer effect of saffron and its constituents has been established. Polyethylene glycolated nanoliposomes with a size range up to 200 nm are ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Rastgoo M,Hosseinzadeh H,Alavizadeh H,Abbasi A,Ayati Z,Jaafari MR

    更新日期:2013-04-01 00:00:00

  • Changes in the histomorphometric and biomechanical properties of the proximal femur of ovariectomized rat after treatment with the phytoestrogens genistein and equol.

    abstract::The isoflavonoids found in soy have attracted great interest as dietary phytoestrogens that might be effective for postmenopausal hormone replacement therapy. Special attention has been devoted to the hormonal effects of various isoflavonoids, like genistein (GEN) and daidzein's (DAID) potent metabolite, equol (EQ). H...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Tezval M,Sehmisch S,Seidlová-Wuttke D,Rack T,Kolios L,Wuttke W,Stuermer KM,Stuermer EK

    更新日期:2010-02-01 00:00:00

  • Effects of Evodia rutaecarpa and rutaecarpine on the pharmacokinetics of caffeine in rats.

    abstract::To assess possible herb-drug interactions, rutaecarpine (an herbal ingredient of Evodia rutaecarpa; 25 mg/kg/day, p. o.), the ethanol extract of Evodia rutaecarpa (1 g/kg/day, p. o.), and an herbal preparation of Evodia rutaecarpa (Wu-Chu-Yu-Tang; 1 g/kg/day) were individually pretreated daily for three consecutive da...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Tsai TH,Chang CH,Lin LC

    更新日期:2005-07-01 00:00:00

  • Cycloartane triterpenoids from Cassia occidentalis.

    abstract::A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds we...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Li SF,Di YT,Luo RH,Zheng YT,Wang YH,Fang X,Zhang Y,Li L,He HP,Li SL,Hao XJ

    更新日期:2012-05-01 00:00:00

  • Induction of cytochrome P450s by rutaecarpine and metabolism of rutaecarpine by cytochrome P450s.

    abstract::Rutaecarpine is an alkaloid originally isolated from the unripe fruit of Evodia rutaecarpa. Recently, rutaecarpine has been characterized to have an anti-inflammatory activity through cyclooxygenase-2 inhibition. In the present studies, the effects of rutaecarpine on liver cytochrome P450 s (P450s) and P450 s involved...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Lee SK,Kim NH,Lee J,Kim DH,Lee ES,Choi HG,Chang HW,Jahng Y,Jeong TC

    更新日期:2004-08-01 00:00:00

  • Labdane diterpenoids and shikimic acid derivatives from Araucaria cunninghamii.

    abstract::Four new (1-4) and two known compounds (5, 6) were isolated from the aerial parts of Araucaria cunninghamii. By analysis of UV, IR, MS, and NMR, the new compounds were identified as ENT-19-(Z)-coumaroyloxylabda-8(17),13(16),14-triene (1), ENT-19-( E)-coumaroyloxylabda-8(17),13(16),14-triene (2), shikimic acid N-butyl ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Chen J,Chen JJ,Yang LQ,Hua L,Gao K

    更新日期:2011-03-01 00:00:00

  • [New cardioactive drugs II, detection and isolation of cardiotonic amines with ionpair-HPLC].

    abstract::An ionpair-HPLC-technic using a reversed-phase column was developed to screen plant extracts for cardiotonic amines and to isolate them in a preparative scale for direct MS and pharmacological investigations. By this method the positive inotropic tyramine could be isolated from Selenicereus grandiflorus (L.) Britt et ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Wagner H,Grevel J

    更新日期:1982-01-01 00:00:00

  • Hepatoprotective flavonol glycosides from the aerial parts of Rodgersia podophylla.

    abstract::A new acylated flavonoid, quercetin 3- O-alpha- L-(5"- O-acetyl)-arabinofuranoside ( 1), along with six known flavonoids ( 2 - 7) were isolated from the aerial parts of Rodgersia podophylla. The new flavonoid 1 exhibited 50.1 % hepatoprotective activity at a concentration of 100 microM, and the three known compounds 3...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Chin YW,Lim SW,Kim YC,Choi SZ,Lee KR,Kim J

    更新日期:2004-06-01 00:00:00

  • Taspine is the cicatrizant principle in Sangre de Grado extracted from Croton lechleri.

    abstract::Sangre de Grado extract used by Peruvian natives as a cicatrizant agent, was collected from trees of the species Croton lechleri growing in the Peruvian jungle. The Sangre de Grado was found to contain one alkaloid identified as taspine and which was shown to be the active cicatrizant principle by an in vivo test in m...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Vaisberg AJ,Milla M,Planas MC,Cordova JL,de Agusti ER,Ferreyra R,Mustiga MC,Carlin L,Hammond GB

    更新日期:1989-04-01 00:00:00

  • Alkaloids from Hippeastrum equestre. Part I. Phamine, a new phenanthridone alkaloid.

    abstract::From the bulbs of Vietnamese Hippeastrum equestre Herb. (Amaryllidaceae), besides the well known alkaloids lycorine, tazettine, and hippeastrine, a new alkaloid, phamine, has been isolated. Its structure was established by spectroscopic methods. ...

    journal_title:Planta medica

    pub_type: 信件


    authors: Döpke W,Pham LH,Gründemann E,Bartoszek M,Flatau S

    更新日期:1995-12-01 00:00:00

  • Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina.

    abstract::O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(α-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(α-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts of Moringa peregrina. The compounds were tested for in vitro activity against Trypanosoma brucei rhodesiense and cytotoxicity in...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Ayyari M,Salehi P,Ebrahimi SN,Zimmermann S,Portmann L,Krauth-Siegel RL,Kaiser M,Brun R,Rezadoost H,Rezazadeh S,Hamburger M

    更新日期:2014-01-01 00:00:00

  • Distinguishing Vaccinium species by chemical fingerprinting based on NMR spectra, validated with spectra collected in different laboratories.

    abstract::A method was developed to distinguish Vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. Reference spectra were measured on leaf extracts from several species, including lowbush blueberry (Vaccinium angustifolium), oval leaf huckleberry (Vaccinium ovalifolium), and cranberry (Vacci...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Markus MA,Ferrier J,Luchsinger SM,Yuk J,Cuerrier A,Balick MJ,Hicks JM,Killday KB,Kirby CW,Berrue F,Kerr RG,Knagge K,Gödecke T,Ramirez BE,Lankin DC,Pauli GF,Burton I,Karakach TK,Arnason JT,Colson KL

    更新日期:2014-06-01 00:00:00