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Quantitative study of aluminum binding to human serum albumin and transferrin by a chelex competitive binding assay.

Abstract：

:Binding of aluminum to human serum albumin and transferrin was investigated using a competitive binding assay incorporating a cation exchange resin, chelex. Both albumin and transferrin were found to produce linear Scatchard plots of aluminum binding data over the aluminum and protein concentration ranges found in humans. Binding constants measured for albumin and transferrin were 1.96 and 0.515 microM, respectively.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Bertholf RL,Wills MR,Savory J

doi

10.1016/0006-291x(84)91385-8

subject

Has Abstract

pub_date

1984-12-28 00:00:00

pages

1020-4

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(84)91385-8

journal_volume

125

pub_type

杂志文章

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