Amino acids control ammonia pulses in yeast colonies.

abstract：:Our earlier studies on cell adhesion to immobilized carbohydrates are extended here to a marine bacterium, Vibrio furnissii. Apparently one lectin mediates the binding of these cells to glycosides of N-acetylglucosamine, mannose, and glucose covalently linked to Agarose beads. Kinetic studies show that protein synthes...

journal_title：Biochemical and biophysical research communications

authors： Yu C,Lee AM,Roseman S

更新日期：1987-11-30 00:00:00

abstract：:p70 S6 kinase (p70 S6k) is important in regulating a variety of cellular functions including mRNA translation and cell cycle progression and is activated by mitogens and hormones. Unexpectedly, we have found that, in adult rat cardiomyocytes, arsenite, which generally induces stress responses, markedly and rapidly act...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Proud CG

更新日期：1997-09-08 00:00:00

abstract：:beta-Amyloid peptide (beta A) is a major fibrillar component of neuritic plaques in Alzheimer's disease (AD) brains and is related to the pathogenesis of the disease. In this study, using electron microscopy, we describe herein the results concerning the efficacy of compounds that can dissolve preformed beta A fibrils...

journal_title：Biochemical and biophysical research communications

authors： Nguyen KV,Gendrault JL,Wolff CM

更新日期：2002-03-08 00:00:00

abstract：:Autophagy is the bulk degradation of cytosolic materials in lysosomes/vacuoles of eukaryotic cells. In the yeast Saccharomyces cerevisiae, 17 Atg proteins are known to be involved in autophagosome formation. Genome wide analyses have shown that Atg17 interacts with numerous proteins. Further studies on these interacti...

journal_title：Biochemical and biophysical research communications

authors： Kabeya Y,Kawamata T,Suzuki K,Ohsumi Y

更新日期：2007-05-04 00:00:00

abstract：:Rbfox3, a neuron-specific RNA-binding protein, plays an important role in neuronal differentiation during development. An isoform Rbfox3-d31, which excludes the 93-nucleotide cassette exon within the RNA recognition motif of chicken Rbfox3, has been previously identified. However, the cellular functions of Rbfox3-d31 ...

journal_title：Biochemical and biophysical research communications

authors： Kim KK,Adelstein RS,Kawamoto S

更新日期：2014-08-08 00:00:00

abstract：:We developed a modified method enabling stable MALDI-MS analysis and fluorescent detection of sialyl-compounds. The modification involved the amidation of sialic acid (Neu5Ac) at the position of the carboxyl group using the fluorescent reagent, 2-(2-pyridilamino)ethylamine (PAEA). In this study the following sialyl-co...

journal_title：Biochemical and biophysical research communications

authors： Endo S,Morita M,Ueno M,Maeda T,Terabayashi T

更新日期：2009-01-23 00:00:00

abstract：:The effect of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] on the growth of normal human keratinocytes cultured in serum-free medium was investigated. 1,25(OH)2D3 inhibited the cell growth at 10(-7) M by 75.3% and at 10(-6) M almost completely. The growth inhibition was accompanied by changes related to proliferation: (1) r...

journal_title：Biochemical and biophysical research communications

authors： Matsumoto K,Hashimoto K,Nishida Y,Hashiro M,Yoshikawa K

更新日期：1990-01-30 00:00:00

abstract：:There are tremendous drug candidates that suffer from insolubility in water. In the present study, it is shown that Coenzyme Q10 (CoQ10), a model water-insoluble compound, can be nanoparticulated into a water-soluble form using apolipoprotein A-I (apoA-I). Similar to the way that apoA-I forms nascent discoidal high de...

journal_title：Biochemical and biophysical research communications

authors： Shin JY,Shin JI,Kim JS,Yang YS,Hwang Y,Yang JS,Shin D,Seo JH,Jin YS,Park YC,Hwang JS,Kweon DH

更新日期：2009-10-16 00:00:00

abstract：:Tissue transglutaminase (tTgase) contributes to the organisation of the basement membrane and is therefore thought to be important for the integrity and stability of the vessel wall. In the present study, we hypothesised that the HMG-CoA reductase inhibitor atorvastatin may up-regulate the tTgase expression in endothe...

journal_title：Biochemical and biophysical research communications

authors： Soehnlein O,Eskafi S,Schmeisser A,Kloos H,Daniel WG,Garlichs CD

更新日期：2004-09-10 00:00:00

abstract：:The ΔpH-dependent/Tat pathway is unique for using only the proton motive force for driving proteins transport across the thylakoid membrane in chloroplasts. 9-aminoacridine fluorescence quenching is widely used to monitor the ΔpH developed across the thylakoid membrane in the light. However, this method suffers from l...

journal_title：Biochemical and biophysical research communications

authors： Yang H,Pu X,Wang L,Liu L,Theg SM

更新日期：2017-04-22 00:00:00

abstract：:Sequence-specific hybridization of antisense and antigene agent to the target nucleic acid is an important therapeutic strategy to modulate gene expression. However, efficiency of such agents falls due to inherent intramolecular-secondary-structures present in the target that pose competition to intermolecular hybridi...

journal_title：Biochemical and biophysical research communications

authors： Kaur H,Wengel J,Maiti S

更新日期：2007-01-05 00:00:00

abstract：:Parkinson's disease (PD) is neurodegenerative diseases caused by the loss of dopaminergic neurons in the substantia nigra pars compacta. Stem cell therapy is one of the promising strategies in helping to cure PD. In the present study, human mesenchymal stem cells (MSCs) from eye conjunctiva stromal cells were differen...

journal_title：Biochemical and biophysical research communications

authors： Nadri S,Soleimani M,Mobarra Z,Amini S

更新日期：2008-12-12 00:00:00

abstract：:In the current study, we have examined the role of serotonin in regulating the levels of methyl farnesoate and ecdysteroids in the giant mud crab Scylla serrata and validated that serotonin indeed is a reproductive hormone. Administration of serotonin elevated circulatory levels of methyl farnesoate and ecdysteroids i...

journal_title：Biochemical and biophysical research communications

authors： Girish BP,Swetha CH,Reddy PS

更新日期：2017-09-02 00:00:00

abstract：:Chromatin-associated high mobility group (HMG) proteins of the HMGB family are versatile architectural factors assisting various DNA-dependent processes such as transcription and recombination. Here, transgenic tobacco lines were generated that ectopically express the maize HMGB1 protein, as detected by immunoblot ana...

journal_title：Biochemical and biophysical research communications

authors： Lichota J,Ritt C,Grasser KD

更新日期：2004-05-21 00:00:00

abstract：:Tetrodotoxin-binding sites were covalently labelled with a highly tritiated derivative of tetrodotoxin. Cross-linking experiments, using dissucinimidyl suberate, on partially purified tetrodotoxin-binding component from electroplax of Electrophorus electricus, revealed covalent labelling of a single polypeptide chain ...

journal_title：Biochemical and biophysical research communications

authors： Lombet A,Norman RI,Lazdunski M

更新日期：1983-07-18 00:00:00

abstract：:Two cis-acting elements GM-kappa B/GC-box and CLE0, of the granulocyte-macrophage colony-stimulating factor (GM-CSF) gene are required for maximal induction in Jurkat T cells by costimulation with phorbol-12-myristate acetate (PMA) and Ca2+ ionophore (A23187). The GM-kappa B sequence is recognized by NF-kappa B, which...

journal_title：Biochemical and biophysical research communications

authors： Tsuboi A,Muramatsu M,Tsutsumi A,Arai K,Arai N

更新日期：1994-03-15 00:00:00

abstract：:Major histocompatibility complex class II (MHC II) molecules are mainly expressed on antigen presentation cells and play an important role in immune response. It has been reported that MHC II molecules are also detected in serum as a soluble form (sMHC II molecules), and they are considered to be involved in the maint...

journal_title：Biochemical and biophysical research communications

authors： Shishido T,Kohyama M,Nakai W,Matsumoto M,Miyata H,Suenaga T,Arase H

更新日期：2019-01-29 00:00:00

abstract：:The major form of cytochrome P-450, P-450K-5, was purified from kidney microsomes of untreated male rats with high-performance liquid chromatography with anion-exchange and hydroxylapatite columns. The monomeric molecular weight of P-450K-5 was 52000 on SDS-polyacrylamide gel electrophoresis and the CO-reduced absorpt...

journal_title：Biochemical and biophysical research communications

authors： Imaoka S,Funae Y

更新日期：1986-12-15 00:00:00

abstract：PURPOSE:Cancer stem cells (CSCs), also known as tumor-initiating cells, are involved in tumor progression, metastasis, and drug resistance. Hybrid liposomes (HLs) are nano-sized liposomal particles that can be easily prepared by ultrasonicating a mixture of vesicular and micellar molecules in buffer solutions. In this ...

journal_title：Biochemical and biophysical research communications

authors： Inamura K,Komizu Y,Yamakuchi M,Ishida S,Matsumoto Y,Matsushita T

更新日期：2019-01-29 00:00:00

abstract：:Diallyl trisulfide (DATS), one of the volatile constituents of garlic oil, has been reported to possess antioxidant, anti-inflammatory, and anti-carcinogenic properties. In this study, DATS (10μmol) given orally for 7days before and for another 7days after starting administration of 2.5% dextran sulfate sodium (DSS) i...

journal_title：Biochemical and biophysical research communications

authors： Lee HJ,Lee HG,Choi KS,Surh YJ,Na HK

更新日期：2013-07-26 00:00:00

abstract：:Flo8 is a transcriptional activator essential for the inducible expression of a set of target genes such as STA1, FLO11, and FLO1 encoding an extracellular glucoamylase and two cell surface proteins, respectively. However, the molecular mechanism of Flo8-mediated transcriptional activation remains largely elusive. By ...

journal_title：Biochemical and biophysical research communications

authors： Kim HY,Lee SB,Kang HS,Oh GT,Kim T

更新日期：2014-06-27 00:00:00

abstract：:Adipose tissue plays a key role in the development of obesity and diabetes. Natural products are one of the main sources for discovering new lead compounds. In the present study, (2S)-7,4'-dihydroxy-8-prenylflavan (DHPF), a natural prenylated flavan isolated from Morus yunnanensis, was found to significantly promote a...

journal_title：Biochemical and biophysical research communications

authors： Ji J,Zhu J,Hu X,Wang T,Zhang X,Hou AJ,Wang H

更新日期：2015-05-08 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) is a small neuropeptide, which exerts pleiotropic functions. Based on its immunomodulatory, secretory, and possibly trophic effects, VIP is a valuable candidate molecule for the management of autoimmune disease. The purpose of this study was to develop a recombinant viral vector cap...

journal_title：Biochemical and biophysical research communications

authors： Lodde BM,Delporte C,Goldsmith CM,Tak PP,Baum BJ

更新日期：2004-06-18 00:00:00

abstract：:The characteristics of carcinoembryonic antigen (CEA) molecules expressed by different cell types have been examined using cDNA transfection into cells of epithelial, neuroectodermal and hematopoietic origin. Variability in the CEA molecules was observed in terms of monoclonal antibody binding, apparent molecular weig...

journal_title：Biochemical and biophysical research communications

authors： Grimm T,Riethmüller G,Johnson JP

更新日期：1994-11-15 00:00:00

abstract：:The ZntR protein from Escherichia coli is a member of the MerR-family of transcriptional regulatory proteins and acts as a hyper-sensitive transcriptional switch primarily in response to Zn(II) and Cd(II). The binding of metal-ions to ZntR initiates a mechanism that remodels the cognate promoter, increasing its affini...

journal_title：Biochemical and biophysical research communications

authors： Khan S,Brocklehurst KR,Jones GW,Morby AP

更新日期：2002-12-06 00:00:00

abstract：:Several fusion proteins of mouse Interleukins (mILs) and the enhanced green fluorescent protein (EGFP) were expressed in fibroblast and epithelial cells. Among these proteins, the mIL-31 derivative was the most efficiently secreted into the medium in a N-glycosylation-dependent manner. From the analysis of deletion mu...

journal_title：Biochemical and biophysical research communications

authors： Akiyama N,Ohno Y,Fukuda T,Manome Y,Saito S

更新日期：2009-04-17 00:00:00

abstract：:We have previously reported that the two components of R2TP complex, RNA polymerase II-associated protein 3 (RPAP3), and Reptin, regulate apoptosis. Here we characterize another component of the complex, PIH1 domain containing protein 1 (PIH1D1). PIH1D1 interacts with both RPAP3 and Monad in HEK293 or U2OS cells. PIH1...

journal_title：Biochemical and biophysical research communications

authors： Inoue M,Saeki M,Egusa H,Niwa H,Kamisaki Y

更新日期：2010-12-17 00:00:00

abstract：:Three different domains of human sperm membrane, viz., the hydrophobic domains, the aqueous compartments and the surface proteins were probed to evaluate the molecular dynamics in these microenvironments in normal as well as oligospermic cases. Decreased rotational motion of the stearic spin-labels, designated rigid l...

journal_title：Biochemical and biophysical research communications

authors： Sinha S,Kumar GP,Laloraya M

更新日期：1994-01-14 00:00:00

abstract：:We previously reported synergistic induction of apoptosis by IFN-gamma plus either cyclosporin A (CsA) or tacrolimus (FK506) in gastric carcinoma cells. In this study, we aimed to elucidate the mechanism for this synergistic induction of apoptosis. IFN-gamma plus CsA synergistically induced caspase-3 mediated apoptosi...

journal_title：Biochemical and biophysical research communications

authors： Beppu K,Morisaki T,Matsunaga H,Uchiyama A,Ihara E,Hirano K,Kanaide H,Tanaka M,Katano M

更新日期：2003-06-13 00:00:00

abstract：:Fracture healing is a complicated regeneration process which to some extent recapitulates bone development. Fibroblast growth factor receptor 3 (FGFR3) has a negative regulatory effect on endochondral ossification, and FGFR3 is also expressed in prehypertrophic and hypertrophic chondrocytes during fracture healing. Ho...

journal_title：Biochemical and biophysical research communications

authors： Su N,Yang J,Xie Y,Du X,Lu X,Yin Z,Yin L,Qi H,Zhao L,Feng J,Chen L

更新日期：2008-11-21 00:00:00