GPR35 is a functional receptor in rat dorsal root ganglion neurons.

abstract：:A combination of the RT-PCR method and subsequent screening of the cDNA library of mouse skeletal muscle with the cDNA isolated by RT-PCR used as a probe led to isolation of cDNAs encoding a polypeptide (mSim) with bHLH and PAS domains which show high similarity to the corresponding regions of Drosophila Sim, a master...

journal_title：Biochemical and biophysical research communications

authors： Ema M,Suzuki M,Morita M,Hirose K,Sogawa K,Matsuda Y,Gotoh O,Saijoh Y,Fujii H,Hamada H,Fujii-Kuriyama Y

更新日期：1996-01-17 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is a potent and specific mitogen for vascular endothelial cells. A 3.9 kb VEGF transcript is expressed by all cardiac tissues from rat, mouse and guinea pig examined. VEGF expression was not developmentally regulated. The major form of VEGF mRNAs expressed by cardiac tissues c...

journal_title：Biochemical and biophysical research communications

authors： Ladoux A,Frelin C

更新日期：1993-09-15 00:00:00

abstract：:During the course of investigations on the catabolism of acetylpolyamines by microorganisms, we found that acetylpolyamine amidohydrolase was produced by Mycoplana bullata FERM BP-1845 and isolated the enzyme from the cell-free extract in crystalline form. The enzyme had an apparent molecular weight of 67 kDa and was ...

journal_title：Biochemical and biophysical research communications

authors： Fujishiro K,Ando M,Uwajima T

更新日期：1988-12-30 00:00:00

abstract：:A monoclonal antibody (MaB) against mouse sarcoma DNA polymerase alpha was isolated from the culture medium of an IgG-secreting hybridoma. The MaB demonstrated reactivity against two murine DNA polymerase alpha preparations and a calf thymus DNA polymerase alpha. Murine sarcoma polymerase was activated in vitro by pho...

journal_title：Biochemical and biophysical research communications

authors： Sylvia VL,Norman JO,Curtin GM,Busbee DL

更新日期：1986-11-26 00:00:00

abstract：:How rod-shaped bacteria form and maintain their shape is an important question in bacterial cell biology. Results from fluorescent light microscopy have led many to believe that the actin homolog MreB and a number of other proteins form long helical filaments along the inner membrane of the cell. Here we show using el...

journal_title：Biochemical and biophysical research communications

authors： Swulius MT,Chen S,Jane Ding H,Li Z,Briegel A,Pilhofer M,Tocheva EI,Lybarger SR,Johnson TL,Sandkvist M,Jensen GJ

更新日期：2011-04-22 00:00:00

abstract：:5-Bromodeoxyuridine (BrdU) modulates expression of particular genes associated with cellular differentiation and senescence. Our previous studies have suggested an involvement of chromatin structure in this phenomenon. Here, we examined the effect of 5-bromouracil on nucleosome positioning in vivo using TALS plasmid i...

journal_title：Biochemical and biophysical research communications

authors： Miki K,Shimizu M,Fujii M,Hossain MN,Ayusawa D

更新日期：2008-04-11 00:00:00

abstract：:The 100,000 x g supernatant of bovine heart has been chromatographed on DEAE-cellulose and the resultant fractions have been analyzed for both calcium binding activity and calmodulin activity. Of the four peaks of calcium binding activity detected by this procedure only a single peak (peak IV) was identified as calmod...

journal_title：Biochemical and biophysical research communications

authors： Waisman DM,Khanna NC,Tokuda M

更新日期：1986-09-14 00:00:00

abstract：:In addition to its interaction at hypothalamic sites to affect feeding and energy expenditure, leptin has been shown to exhibit a proliferative response in erythropoietic cells. The functional leptin receptor is also present in pancreatic islets and we now demonstrate that a commonly used clonal insulin secreting beta...

journal_title：Biochemical and biophysical research communications

authors： Islam MS,Morton NM,Hansson A,Emilsson V

更新日期：1997-09-29 00:00:00

abstract：:Polymerization of actin induced by activation of platelets was investigated using deoxyribonuclease I inhibition assay. When platelets were activated with ADP or 5-hydroxytryptamine, actin was polymerized quickly followed by rapid depolymerization to the initial level. Reactivation with the same agonist, however, did ...

journal_title：Biochemical and biophysical research communications

authors： Imada T,Kikuchi T,Shimada H,Inada Y,Saito Y

更新日期：1984-05-16 00:00:00

abstract：:A glycerol kinase (Gyk) knock-out (KO) mouse model permits improved understanding of glycerol kinase (GK) deficiency (GKD) pathogenesis, however, early death of affected mice limits its utility. The purpose of this work was to delay death of affected males to investigate thoroughly their phenotypes. An adenoviral vect...

journal_title：Biochemical and biophysical research communications

authors： Kuwada N,Nagano K,MacLennan N,Havens J,Kumar M,Dipple KM,McCabe ER

更新日期：2005-09-16 00:00:00

abstract：:CD36 expressed on adipocytes is thought to function as a fatty acid transporter (FAT). Here we report that adipocytes can endocytose and lysosomally degrade OxLDL, mainly mediated by CD36. Mouse 3T3-L1 preadipocytes showed marked increase in uptake and degradation of (125)I-OxLDL during their differentiation to adipoc...

journal_title：Biochemical and biophysical research communications

authors： Kuniyasu A,Hayashi S,Nakayama H

更新日期：2002-07-12 00:00:00

abstract：:Endothelin (ET)-related peptides including ET-1 (1-39) were synthesized, and their constricting activity in rat pulmonary artery rings and pressor activity in unanesthetized rat were measured to elucidate their structure-activity relationship. The vasoconstrictor activities of ET-2, ET-3 and sarafotoxin S6b were one-h...

journal_title：Biochemical and biophysical research communications

authors： Nakajima K,Kubo S,Kumagaye S,Nishio H,Tsunemi M,Inui T,Kuroda H,Chino N,Watanabe TX,Kimura T

更新日期：1989-08-30 00:00:00

abstract：:Endocannabinoids including anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are important lipid mediators for immunosuppressive effects and for appropriate homeostasis via their G-protein-coupled cannabinoid (CB) receptors in mammalian organs and tissues, and may be involved in wound healing in some organs. The phys...

journal_title：Biochemical and biophysical research communications

authors： Kozono S,Matsuyama T,Biwasa KK,Kawahara K,Nakajima Y,Yoshimoto T,Yonamine Y,Kadomatsu H,Tancharoen S,Hashiguchi T,Noguchi K,Maruyama I

更新日期：2010-04-16 00:00:00

abstract：:A type II DNA topoisomerase has been partially purified from calf thymus mitochondria by a combination of differential centrifugation and column chromatography. The mitochondrial enzyme was inhibited by amsacrine (m-AMSA) slightly at 0.5 microM, significantly at 5.0 microM, and completely at 50 microM. A similar profi...

journal_title：Biochemical and biophysical research communications

authors： Lin JH,Castora FJ

更新日期：1991-04-30 00:00:00

abstract：:A novel membrane-soluble prodrug of the 5'-monophosphate derivative of 3TC containing a phenyl group and the methyl ester of L-alanine linked to the phosphorus through a phosphoramidate bond with the primary amino moiety (designated Cf 1109) was prepared. The 3TC prodrug proved less potent an inhibitor of HIV-1 and HI...

journal_title：Biochemical and biophysical research communications

authors： Balzarini J,Wedgwood O,Kruining J,Pelemans H,Heijtink R,De Clercq E,McGuigan C

更新日期：1996-08-14 00:00:00

abstract：:We have recently demonstrated that exposure of MCF7 cells to antiestrogens in vitro results in both accumulation of IGF-BP3 in media and reduced mitogenic responsivity to IGFs (Cancer Res. 53:5193-5198). We show here that MCF7 cell proliferation in steroid-stripped, serum containing media is significantly attenuated b...

journal_title：Biochemical and biophysical research communications

authors： Pratt SE,Pollak MN

更新日期：1994-01-14 00:00:00

abstract：BACKGROUND:Quercetin is a plant polyphenol from the flavonoid group that plays a fundamental role in controlling homeostasis due to its potent antioxidant properties. However, quercetin has extremely low water solubility, which is a major challenge in drug absorption. METHOD:In this study, we described a simple method...

journal_title：Biochemical and biophysical research communications

authors： Aghapour F,Moghadamnia AA,Nicolini A,Kani SNM,Barari L,Morakabati P,Rezazadeh L,Kazemi S

更新日期：2018-06-12 00:00:00

abstract：:Mutations in collagen II are associated with spondyloepiphyseal dysplasia, a group of heritable diseases whose common features include aberrations of skeletal growth. The mechanisms through which mutations in collagen II affect the cartilaginous tissues are complex and include both intracellular and extracellular proc...

journal_title：Biochemical and biophysical research communications

authors： Gawron K,Jensen DA,Steplewski A,Fertala A

更新日期：2010-05-28 00:00:00

abstract：:The I domains of CD11 are responsible for the binding of ligands and have a unique structure with 6-7 alpha helices and 6 beta sheets with interconnecting loops. To determine loops recognizing fibrinogen in CD11c I domain, five oligopeptides corresponding to CD11c loops were used to prevent fibrinogen binding to isola...

journal_title：Biochemical and biophysical research communications

authors： Choi J,Nham SU

更新日期：2002-04-05 00:00:00

abstract：:Insulin-stimulated GLUT4 recruitment to the plasma membrane is impaired in insulin resistance. We recently reported that a cell permeable phosphoinositide-binding peptide induces GLUT4 recruitment as potently as insulin, but does not activate GLUT4 to initiate glucose uptake. Here we investigated whether the peptide-i...

journal_title：Biochemical and biophysical research communications

authors： Funaki M,Benincasa K,Randhawa PK

更新日期：2007-09-07 00:00:00

abstract：:ATP-binding cassette sub-family G member 2 (ABCG2) confers to the major phenotypes of side population (SP) cells, the cancer stem-like cells. In this study, the SP cells displayed a distinctly higher ABCG2 expression level, sphere formation efficiency (SFE) and growth rate even under hypoxia condition. CXCR4 overexpre...

journal_title：Biochemical and biophysical research communications

authors： He C,Zhang H,Wang B,He J,Ge G

更新日期：2018-10-28 00:00:00

abstract：:Dynamic properties of spin-labelled heterosaccharides in the Fc-region of murine monoclonal antihapten immunoglobulin G were studied in model immune complexes (IC) as a function of the IC size. Model IC dimers, trimers and oligomers were formed using bivalent photoaffinity antigens. The ESR spectrum exhibits two compo...

journal_title：Biochemical and biophysical research communications

authors： Kusumi A,Winkelhake JL

更新日期：1986-05-29 00:00:00

abstract：:Separation of proteins by two-dimensional electrophoresis and following mass spectrometry (MS) is now a conventional technique for proteomic analysis. For proteomic analysis of a certain tissue with a limited information of primary structures of proteins, we have developed an analytical system for peptide mass fingerp...

journal_title：Biochemical and biophysical research communications

authors： Hozumi A,Satouh Y,Ishibe D,Kaizu M,Konno A,Ushimaru Y,Toda T,Inaba K

更新日期：2004-07-09 00:00:00

abstract：:The oral mucosa is susceptible to tissue injury from many causes, including infection, autoimmune disorders, surgical and accidental trauma, and gingival and periodontal inflammation; however, little is known about the events that influence wound healing in the mouth. Recent studies in non-oral tissues have implicated...

journal_title：Biochemical and biophysical research communications

authors： McGrory K,Flaitz CM,Klein JR

更新日期：2004-11-05 00:00:00

abstract：:We have previously shown that sphingosine 1-phosphate (S1P) stimulates motility of human umbilical vein endothelial cells (HUVECs) (O.-H. Lee et al., Biochem. Biophys. Res. Commun. 264, 743-750, 1999). To investigate the molecular mechanisms by which S1P stimulates HUVEC motility, we examined tyrosine phosphorylation ...

journal_title：Biochemical and biophysical research communications

authors： Lee OH,Lee DJ,Kim YM,Kim YS,Kwon HJ,Kim KW,Kwon YG

更新日期：2000-02-05 00:00:00

abstract：:Cellobiose triggers the production of two endoglucanases, EglA and EglB, in Aspergillus nidulans. The cellulose responsive element (CeRE) cis-element that is essential for induction has been identified on the eglA promoter, but transcription factors that bind to CeRE have not yet been identified. CeRE contained a cons...

journal_title：Biochemical and biophysical research communications

authors： Yamakawa Y,Endo Y,Li N,Yoshizawa M,Aoyama M,Watanabe A,Kanamaru K,Kato M,Kobayashi T

更新日期：2013-02-22 00:00:00

abstract：BACKGROUND/AIMS:Pancreatic islet transplantation is an effective treatment for Type 1 diabetic patients to eliminate insulin injections; however, a shortage of donor organs hinders the widespread use. Although long-term islet storage, such as cryopreservation, is considered one of the key solutions, transplantation of ...

journal_title：Biochemical and biophysical research communications

authors： Komatsu H,Barriga A,Medrano L,Omori K,Kandeel F,Mullen Y

更新日期：2017-05-06 00:00:00

abstract：:Transcription factors play a crucial role in the development of various tissues. In particular, the transcription factors of the basic helix-loop-helix (bHLH) family are crucial regulators of neurodifferentiation. Previous studies suggested that the bHLH transcription factor Hand2 is essential for sympathetic nervous ...

journal_title：Biochemical and biophysical research communications

authors： Hashimoto Y,Tsutsumi M,Myojin R,Maruta K,Onoda F,Tashiro F,Ohtsu M,Murakami Y

更新日期：2011-04-29 00:00:00

abstract：:Soluble guanylyl cyclase (sGC) is activated by nitric oxide (NO) and generates the second messenger cyclic GMP (cGMP). Recently, purified sGC α1β1 has been shown to additionally generate the cyclic pyrimidine nucleotides cCMP and cUMP. However, since cyclic pyrimidine nucleotide formation occurred only the presence of...

journal_title：Biochemical and biophysical research communications

authors： Bähre H,Danker KY,Stasch JP,Kaever V,Seifert R

更新日期：2014-01-24 00:00:00

abstract：:Fusing recombinant proteins to highly soluble partners is frequently used to prevent aggregation of recombinant proteins in Escherichia coli. Moreover, co-overexpression of prokaryotic chaperones can increase the amount of properly folded recombinant proteins. To understand the solubility enhancement of fusion protein...

journal_title：Biochemical and biophysical research communications

authors： Douette P,Navet R,Gerkens P,Galleni M,Lévy D,Sluse FE

更新日期：2005-08-05 00:00:00