Cloning, characterization, and mapping of the gene encoding the human G protein gamma 2 subunit.

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a well-known immunotoxic compound affecting the expression of inflammatory genes. We found that TCDD induces the expression of the B-cell activating factor of the tumor necrosis factor family (BAFF), B-lymphocyte chemoattractant (BLC), CC-chemokine ligand 1 (CCL1), and the...

journal_title：Biochemical and biophysical research communications

authors： Vogel CF,Sciullo E,Matsumura F

更新日期：2007-11-23 00:00:00

abstract：:The gene encoding a red-shifted green fluorescent protein variant (EGFP) was introduced into a human immunodeficiency virus type 1 (HIV-1) molecular clone by replacing the nef gene. The EGFP-expressing HIV-1 replicated efficiently in established human T cells. The expression of EGFP in the virus-infected cells was con...

journal_title：Biochemical and biophysical research communications

authors： Lee AH,Han JM,Sung YC

更新日期：1997-04-07 00:00:00

abstract：:Adeno-associated virus (AAV) capsids are composed of three proteins, VP1, VP2, and VP3. These capsid proteins have a common amino acid sequence, being expressed from different initiation codons on the same open reading frame. Although VP1 is necessary for viral infection, it is not essential for capsid formation. The ...

journal_title：Biochemical and biophysical research communications

authors： Hoque M,Shimizu N,Ishizu Ki,Yajima H,Arisaka F,Suzuki K,Watanabe H,Handa H

更新日期：1999-12-20 00:00:00

abstract：:Nerve growth factor (NGF) immobilization on a culture substrate may dramatically reduce the amount of NGF required for pheochromocytoma (PC12) cell culture. Coverslips on which NGF had been immobilized, or with NGF added to the culture medium daily, were used to culture PC12 cells. We examined the effects of adding 5,...

journal_title：Biochemical and biophysical research communications

authors： Bhang SH,Lee TJ,Yang HS,La WG,Han AM,Kwon YH,Kim BS

更新日期：2009-05-01 00:00:00

abstract：:The effects of high (28mM) D-glucose (HG) on the cell cycle progression were investigated in rat aorta vascular smooth muscle cells (VSMCs) in primary culture, using an immunocytochemical analysis of cell-cycle-specific nuclear antigens. HG had no effect on the cell cycle of the serum-deprived G0 cells, whereas platel...

journal_title：Biochemical and biophysical research communications

authors： Hiroishi G,Kobayashi S,Nishimura J,Inomata H,Kanaide H

更新日期：1995-06-15 00:00:00

abstract：:Actin bundling protein 34 (ABP34) is the one of 11 actin-crosslinking proteins identified in Dictyostelium discoideum, a novel model organism for the study of actin-associated neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. ABP34 localizes at the leading and trailing edges of locomoto...

journal_title：Biochemical and biophysical research communications

authors： Chung JM,Kim HU,Kim GJ,Jeoung D,Jung HS

更新日期：2018-09-10 00:00:00

abstract：:Phospholipase D has been implicated as an important enzyme in a range of cellular responses, including regulated secretion and the formation of secretory vesicles, cell proliferation and control of cell morphology. As insulin treatment of adipocytes has been shown to stimulate a phosphatidylcholine-specific phospholip...

journal_title：Biochemical and biophysical research communications

authors： Millar CA,Jess TJ,Saqib KM,Wakelam MJ,Gould GW

更新日期：1999-01-27 00:00:00

abstract：:Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (Dm-dNK) can additionally sensitize human cancer cell lines towards the anti-cancer drug gemcitabine. We show that this property is based on the Dm-dNK ability to efficiently phosphorylate gemcitabine. The 2.2A resolution structure of Dm-dNK in complex ...

journal_title：Biochemical and biophysical research communications

authors： Knecht W,Mikkelsen NE,Clausen AR,Willer M,Eklund H,Gojković Z,Piskur J

更新日期：2009-05-01 00:00:00

abstract：:KK mice are genetically diabetic animals, showing glucose intolerance and insulin resistance. We examined the effects of 3,3',5-triiodo-L-thyronine (T3) on the blood glucose level and on mRNA levels of muscle cell differentiation markers in hyperglycemic KK mice. T3 treatment (T1, 1 mg; T3, 3 mg; T10, 10 mg/kg/day) of...

journal_title：Biochemical and biophysical research communications

authors： Shimokawa T,Kato M,Shioduka K,Irie J,Ezaki O

更新日期：1997-06-27 00:00:00

abstract：:Zinc is an essential element for the biological system. However, excessive exogenous Zn2+ would disrupt cellular Zn2+ homeostasis and cause toxicity. In particular, Zinc salts or ZnO nanoparticles exposure could induce respiratory injury. Although previous studies have indicated that organelle damage (including mitoch...

journal_title：Biochemical and biophysical research communications

authors： Qin X,Zhang J,Wang B,Xu G,Zou Z

更新日期：2017-06-17 00:00:00

abstract：:ERK5, a member of the mitogen activated protein kinase, expressed in the kidneys was smaller (∼80kDa) in apparent molecular mass compared to other organs (∼120kDa). A blocking peptide experiment confirmed that the ∼80kDa detected on Western blots was a specific band detected by the anti-ERK5 antibody. Expression of th...

journal_title：Biochemical and biophysical research communications

authors： Kawakami T,Park SW,Kaku R,Yang J

更新日期：2012-02-24 00:00:00

abstract：:The influence of retinoic acid on the incorporation of [1-14C]palmitic acid and [1-14C]arachidonic acid into phospholipids was examined in guinea pig peritoneal granulocytes. All-trans-retinoic acid inhibited the incorporation of both fatty acids into phosphatidic acid and phosphatidylinositol. However, it stimulated ...

journal_title：Biochemical and biophysical research communications

authors： Tou J

更新日期：1983-07-18 00:00:00

abstract：:Altering the carbohydrate binding properties of surfactant protein D (SP-D) [e.g., by replacing its carbohydrate recognition domain (CRD) with that of either mannose binding lectin (MBL) or conglutinin] can increase its activity against influenza A virus (IAV). The current study demonstrates that the degree of multime...

journal_title：Biochemical and biophysical research communications

authors： White MR,Crouch E,Chang D,Hartshorn KL

更新日期：2001-08-10 00:00:00

abstract：:Recently, Bmi1 was shown to control the proliferation and self-renewal of neural stem cells (NSCs). In this study, we demonstrated the induction of NSC-like cells (NSCLCs) from mouse astrocytes by Bmi1 under NSC culture conditions. These NSCLCs exhibited the morphology and growth properties of NSCs, and expressed NSC ...

journal_title：Biochemical and biophysical research communications

authors： Moon JH,Yoon BS,Kim B,Park G,Jung HY,Maeng I,Jun EK,Yoo SJ,Kim A,Oh S,Whang KY,Kim H,Kim DW,Kim KD,You S

更新日期：2008-06-27 00:00:00

abstract：:Cellular prion protein (PrP(C)) is expressed not only in neuronal cells but also in non-neuronal cells such as astroglial cells. In the present study, the prion protein (PrP) gene (Prnp)-deficient astroglial cell line GpL1 from hippocampal cells of ZrchI Prnp(-/-) mice were established. Transfection of Prnp suppressed...

journal_title：Biochemical and biophysical research communications

authors： Nishimura T,Sakudo A,Xue G,Ikuta K,Yukawa M,Sugiura K,Onodera T

更新日期：2008-12-26 00:00:00

abstract：:The high affinity laminin receptor is differentially expressed in metastasis. We now report that there are multiple copies (6 +/- 1) of the laminin receptor gene in the murine genome of normal diploid cells as well as in cell lines derived from cancer cells. We have analyzed three distinct cDNA clones isolated from an...

journal_title：Biochemical and biophysical research communications

authors： Fernández MT,Castronovo V,Rao CN,Sobel ME

更新日期：1991-02-28 00:00:00

abstract：:Multiple types of connexin (Cxs) products, including Cx26, Cx30, Cx31, and Cx43, are found by immunolabeling in the mature cochlea. The transcript of Cx29, a newly discovered member of Cx gene family, was also discovered in the cochlea by cDNA macroarray hybridization. However, the functional roles of Cx29 in the coch...

journal_title：Biochemical and biophysical research communications

authors： Yang JJ,Liao PJ,Su CC,Li SY

更新日期：2005-12-16 00:00:00

abstract：:The iron molybdenum cofactor of Azotobacter vinelandii nitrogenase has been solubilized for the first time in dimethylformamide and acetonitrile. These solutions have the ability to reconstitute the inactive nitrogenase of the UW 45 mutant of A. vinelandii and exhibit an S = 3/2 EPR signal similar to that for the cofa...

journal_title：Biochemical and biophysical research communications

authors： Lough SM,Jacobs DL,Lyons DM,Watt GD,McDonald JW

更新日期：1986-09-14 00:00:00

abstract：:SAP90/PSD95-associated proteins (SAPAPs) are one type of scaffold protein in the postsynaptic density (PSD). Scaffold proteins play an important role in synaptic function. Recently, many studies have shown that mutations associated with scaffold proteins cause dysfunction in neuronal circuitry and in behavior. SAPAP4,...

journal_title：Biochemical and biophysical research communications

authors： Wu B,Li C,Lei H

更新日期：2018-11-10 00:00:00

abstract：:Aldose reductase has been purified to homogeneity from bovine retina. It has an apparent molecular weight of 32,000 daltons and shares immunological and kinetic properties with the much studied aldose reductases purified from various sources. Retinal aldose reductase displays a K(m) of approximately 40 microM with 4-h...

journal_title：Biochemical and biophysical research communications

authors： He Q,Khanna P,Srivastava S,van Kuijk FJ,Ansari NH

更新日期：1998-06-29 00:00:00

abstract：:Diacylglycerols inhibit binding of [20-3H]phorbol 12,13-dibutyrate ([3H]PDBu) to protein kinase C (the phorbol ester receptor). This inhibition could reflect competitive binding by the diglyceride. Alternatively, it might simply represent perturbation of the lipid environment required for binding activity. As predicte...

journal_title：Biochemical and biophysical research communications

authors： Sharkey NA,Blumberg PM

更新日期：1985-12-31 00:00:00

abstract：:The loss of paramagnetism of the stable free radical 4,4'-di-tert.-butyl- diphenyl-1-nitroxy during illumination of the photosensitizer meso-tetrahydroxyphenyl chlorine by light above 620 nm in the absence of oxygen has been followed by kinetic ESR spectroscopy. Addition of the spin trap alpha-(4-pyridyl-1-oxide)- N-t...

journal_title：Biochemical and biophysical research communications

authors： Kriska T,Korecz L,Nemes I,Gál D

更新日期：1995-10-04 00:00:00

abstract：:Mutual interactions between adipocytes and immune cells in white adipose tissue (WAT) are involved in modulation of lipid metabolism in the tissue and also in response to omega-3 polyunsaturated fatty acids (PUFA), which counteract adverse effects of obesity. This complex interplay depends in part on in situ formed an...

journal_title：Biochemical and biophysical research communications

authors： Kuda O,Rombaldova M,Janovska P,Flachs P,Kopecky J

更新日期：2016-01-15 00:00:00

abstract：:Sphingosine-1-phosphate is synthesized by two sphingosine kinases, cytosolic SK1 and nuclear SK2 but SK2 expression was much higher than SK1in mouse skin fibroblasts. However, in SK2-/- cells, SK1 expression was markedly increased to SK2 levels whereas in SK1-/- cells, SK2 expression was unaffected. Ceramide, glucosyl...

journal_title：Biochemical and biophysical research communications

authors： Qin J,Kilkus JP,Dawson G

更新日期：2018-06-07 00:00:00

abstract：:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) holds promising value for cancer therapy due to its capacity to induce apoptosis in cancer cells. Nevertheless, TRAIL therapy is greatly hampered by its resistance. Irigenin (Iri), isoflavonoids, can be isolated from the rhizome of Belamcanda chinensis, a...

journal_title：Biochemical and biophysical research communications

authors： Xu Y,Gao CC,Pan ZG,Zhou CW

更新日期：2018-02-12 00:00:00

abstract：:Antibodies subjected to SDS-polyacrylamide gel electrophoresis and transferred to nitrocellulose paper, have been found to retain the ability to bind specific antigen. This has been demonstrated for two groups of antibodies, directed to a) a large molecular weight glycoprotein of the human milk fat globule and b) huma...

journal_title：Biochemical and biophysical research communications

authors： Mather S,Taylor-Papadimitriou J

更新日期：1985-12-31 00:00:00

abstract：:Pseudohypoaldosteronism type II (PHAII), an autosomal dominant disorder characterized by hypertension, hyperkalemia, and hyperchloremic acidosis, is reportedly due to mutations in WNK1 and WNK4 kinase genes. However, the pathogenesis of the disease remains unknown. Mutations in the WNK1 gene are the deletions in the f...

journal_title：Biochemical and biophysical research communications

authors： Ohta A,Yang SS,Rai T,Chiga M,Sasaki S,Uchida S

更新日期：2006-10-20 00:00:00

abstract：:Endoplasmic reticulum (ER) stress is involved in a wide range of pathological conditions including neurodegenerative disorders, diabetes mellitus, atherosclerosis, inflammation, and infection. The ability of ER stress to induce an inflammatory response is considered to play a role in the pathogenesis of these diseases...

journal_title：Biochemical and biophysical research communications

authors： Shimasaki S,Koga T,Shuto T,Suico MA,Sato T,Watanabe K,Morino-Koga S,Taura M,Okada S,Mori K,Kai H

更新日期：2010-11-12 00:00:00

abstract：:In hair follicle cells APCDD1 inhibits the canonical WNT/β-Catenin pathway and its inactivation is associated with an autosomal dominant form of hair loss. We analyzed the role of APCDD1 for the osteogenic differentiation in dental follicle cells (DFCs) and identified a new and surprising function. Contrarily to hair ...

journal_title：Biochemical and biophysical research communications

authors： Viale-Bouroncle S,Klingelhöffer C,Ettl T,Morsczeck C

更新日期：2015-02-13 00:00:00

abstract：:Cancer cells show characteristic telomere dynamics. Their chromosomes usually have short telomeres and a high telomerase activity. The "telomere crisis model" proposed here suggests that these unique telomeric features are responsible for the progression of cancer. ...

journal_title：Biochemical and biophysical research communications

authors： Ishikawa F

更新日期：1997-01-03 00:00:00