Effect of triiodothyronine on muscle cell differentiation and blood glucose level in hyperglycemic KK mice.

abstract：:A comparison was made of cytosynalin- and MAPs-induced microtubule formation. Cytosynalin (a 35 kDa cytoskeleton-interacting and calmodulin-binding protein) facilitated more rapid and extensive microtubule formation than MAPs. Electron microscopic examination revealed that the cytosynalin-induced microtubules were 24 ...

journal_title：Biochemical and biophysical research communications

authors： Itoh K,Sobue K

更新日期：1987-07-31 00:00:00

abstract：:Signaling pathways for the antiviral and antiproliferative biological effects of type I interferons (IFN) are well established. In this report we demonstrate a novel signaling pathway for IFN-alpha, as it induced rapid phosphorylation of both PKB/Akt and its substrate forkhead. The PI3-kinase inhibitor LY294002 abolis...

journal_title：Biochemical and biophysical research communications

authors： Ruuth K,Carlsson L,Hallberg B,Lundgren E

更新日期：2001-06-15 00:00:00

abstract：:Follicle-stimulating hormone (FSH) levels increase estrogen biosynthesis in obese menopausal women. Ovariectomized mice and 3T3-L1 cells were used to explore estrogen biosynthesis in the decline of ovarian function. After ovariectomy, lipid deposition, and FSH and estrogen levels changed, and feed intake increased sig...

journal_title：Biochemical and biophysical research communications

authors： Cui H,Zhao G,Wen J,Tong W

更新日期：2018-01-15 00:00:00

abstract：:Ceramide, the backbone of sphingolipids, has been reported to be involved in various cellular responses including apoptosis. We recently established and characterized a C2-ceramide-resistant HL-60 subline designated HL-CR. HL-CR cells were resistant to not only ceramide but also anti-cancer drugs including daunorubici...

journal_title：Biochemical and biophysical research communications

authors： Sawai H,Kawai S,Domae N

更新日期：2004-06-18 00:00:00

abstract：:The intracellular parasitic protist Trypanosoma cruzi is the causative agent of Chagas disease in Latin America. In general, pyrimidine nucleotides are supplied by both de novo biosynthesis and salvage pathways. While epimastigotes-an insect form-possess both activities, amastigotes-an intracellular replicating form o...

journal_title：Biochemical and biophysical research communications

authors： Hashimoto M,Morales J,Fukai Y,Suzuki S,Takamiya S,Tsubouchi A,Inoue S,Inoue M,Kita K,Harada S,Tanaka A,Aoki T,Nara T

更新日期：2012-01-20 00:00:00

abstract：:The signal transduction of human 12(S)-lipoxygenase and the regulation of gene activation, induced by epidermal growth factor (EGF), are discussed in this review article. Treatment of human epidermoid carcinoma A431 cells with EGF induces the gene expression of human 12(S)-lipoxygenase, and two Sp1 binding sites resid...

journal_title：Biochemical and biophysical research communications

authors： Chang WC,Chen BK

更新日期：2005-12-09 00:00:00

abstract：:As the development of sequencing technology, more and more circular RNAs (circRNAs) are identified in human cancer tissues. Increasing evidences imply circRNAs are important regulators in tumor progression. Nevertheless, how circRNAs participate in breast cancer development and progression is not well understood. In t...

journal_title：Biochemical and biophysical research communications

authors： Liu Y,Lu C,Zhou Y,Zhang Z,Sun L

更新日期：2018-07-20 00:00:00

abstract：:Macrophages in tumor are mostly M2-polarized and have been reported to promote tumorigenesis, which are also defined as tumor-associated macrophages (TAMs). β-elemene has therapeutic effects against several cancers, however, it remains unknown whether β-elemene could inhibit cancer by targeting TAMs. Herein, we examin...

journal_title：Biochemical and biophysical research communications

authors： Yu X,Xu M,Li N,Li Z,Li H,Shao S,Zou K,Zou L

更新日期：2017-08-19 00:00:00

abstract：:Prostaglandin E(2) (PGE(2)) enhances the mitogenic response to epidermal growth factor (EGF) in hepatocytes, but the underlying mechanisms are not clear. We previously observed that PGE(2) upregulates EGF-induced signalling in the MEK/ERK and PI3K/Akt pathways in hepatocytes. Other investigations have indicated that E...

journal_title：Biochemical and biophysical research communications

authors： Ødegård J,Aasrum M,Tveteraas IH,Bharath SP,Sandnes D,Christoffersen T

更新日期：2012-05-04 00:00:00

abstract：:Almost all bacteria require iron for growth and virulence expression. However, Listeria spp. do not produce any siderophore for iron acquisition. Representative strains of each of the six species of Listeria were examined for their ability to use various compounds as iron suppliers in iron-restricted medium. Here we s...

journal_title：Biochemical and biophysical research communications

authors： Coulanges V,Andre P,Vidon DJ

更新日期：1998-08-19 00:00:00

abstract：:Four peptides possessing both natriuretic activity and smooth muscle relaxant activity were isolated from rat atrium and their amino acid sequences determined. The four peptides designated ANF-I, ANF-II, ANF-III and ANF-IV containing 35, 31, 30 and 25 amino acid residues, respectively, were obtained in a molar ratio o...

journal_title：Biochemical and biophysical research communications

authors： Misono KS,Grammer RT,Fukumi H,Inagami T

更新日期：1984-09-17 00:00:00

abstract：:Genome-wide association studies identified ADAMTS7 as a risk locus for coronary artery disease. In carotid arteries of rats, neointima formation after balloon-mediated injury goes along with enhanced Adamts7 expression. Vice versa, Adamts7-deficient mice display reduced neointima formation following vascular injury. A...

journal_title：Biochemical and biophysical research communications

authors： Müller M,Kessler T,Schunkert H,Erdmann J,Tennstedt S

更新日期：2016-03-11 00:00:00

abstract：:A ferric low-spin species with an anomalously small g3-g1 separation generated by the reaction of Fe(III)tetraphenylporphyrin with t-butylhydroperoxide in the presence of tatramethylammonium hydroxide was characterized by ESR spectroscopy. The reaction kinetics, investigated by monitoring ESR intensity, indicated that...

journal_title：Biochemical and biophysical research communications

authors： Tajima K,Ishizu K,Sakurai H,Ohya-Nishiguchi H

更新日期：1986-03-28 00:00:00

abstract：:A murine genomic clone of about 16 kilobases encompassing putatively entire bone morphogenetic protein (BMP)-4 gene has been isolated. Comparison with the cDNA clones revealed the existence of at least five exons on the 3' side of the clone. There are two alternative transcriptional start sites, one is for the first e...

journal_title：Biochemical and biophysical research communications

authors： Kurihara T,Kitamura K,Takaoka K,Nakazato H

更新日期：1993-05-14 00:00:00

abstract：BACKGROUND:DMSO is routinely infused together with hematopoietic cells in patients undergoing myeloablative therapy and was recently found to inhibit smooth muscle cells proliferation and arterial thrombus formation in the mouse by preventing tissue factor (TF), a key activator of the coagulation cascade. This study wa...

journal_title：Biochemical and biophysical research communications

authors： Asmis L,Tanner FC,Sudano I,Lüscher TF,Camici GG

更新日期：2010-01-22 00:00:00

abstract：:The receptor for calcitonin gene-related peptide (CGRP) has been the target for the development of novel small molecule antagonists for the treatment of migraine. Two such antagonists, BIBN4096BS and MK-0974, have shown great promise in clinical trials and hence a deeper understanding of the mechanism of their interac...

journal_title：Biochemical and biophysical research communications

authors： Miller PS,Barwell J,Poyner DR,Wigglesworth MJ,Garland SL,Donnelly D

更新日期：2010-01-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are shown to potentiate NGF-induced neuronal differentiation in PC12 phaeochromocytoma cells grown on collagen under low-serum conditions. Whereas, cell bodies remained rounded in control medium or with only BMPs present, addition of BMP4 or BMP6 robustly increased the neuritogenic e...

journal_title：Biochemical and biophysical research communications

authors： Althini S,Usoskin D,Kylberg A,ten Dijke P,Ebendal T

更新日期：2003-08-01 00:00:00

abstract：:The anthrax lethal factor (LF) is a Zn(2+)-endopeptidase specific for mitogen-activated protein kinase kinases (MAPKKs), which are cleaved within their N-terminal region. Much line of effort was carried out to elucidate the catalytic activity of LF for designing the inhibitor and to understand the cellular mechanism o...

journal_title：Biochemical and biophysical research communications

authors： Kim J,Chai YG,Yoon MY

更新日期：2004-01-02 00:00:00

abstract：:Topoisomerase 1 (TOP1) poisons like camptothecin (CPT) are currently used in cancer chemotherapy but these compounds can have damaging, off-target effects on neurons leading to cognitive, sensory and motor deficits. To understand the molecular basis for the enhanced sensitivity of neurons to CPT, we examined the effec...

journal_title：Biochemical and biophysical research communications

authors： Rossi SL,Lumpkin CJ,Harris AW,Holbrook J,Gentillon C,McCahan SM,Wang W,Butchbach MER

更新日期：2016-10-14 00:00:00

abstract：:An expression library established in lambda gt11 with cDNA from squamous epithelium of the human upper digestive tract was screened with an antibody raised against keratin 13. A 1.2 kb fragment from the most strongly reacting plaque was sequenced and compared to known type I keratin sequences. The highest degree of ho...

journal_title：Biochemical and biophysical research communications

authors： Schulz P,Wachter E,Hochstrasser K,Wild AG,Mischke D

更新日期：1989-08-15 00:00:00

abstract：:Hepatitis A virus (HAV) protein 3AB is a membrane-interacting protein containing a stretch of 21 hydrophobic amino acid residues. The nature of its membrane association was studied in detail by analysing various deletion mutants. In vivo and in vitro expression of the wild-type protein and its mutants allowed to demon...

journal_title：Biochemical and biophysical research communications

authors： Ciervo A,Beneduce F,Morace G

更新日期：1998-08-10 00:00:00

abstract：:Diverse inner arm dyneins cooperate with outer arm dyneins to produce ciliary beating. This study demonstrates an expression system for inner arm dyneins in Tetrahymena. The motor domain of inner arm dynein (Dyh8p or Dyh12p) was fused with the tail of outer arm dynein (Dyh3p) and expressed in viable DYH3-knockout (vKO...

journal_title：Biochemical and biophysical research communications

authors： Edamatsu M

更新日期：2020-02-26 00:00:00

abstract：:Previous studies have shown that some inflammatory cytokines promote the expression of corticotropin-releasing hormone (CRH) in trophoblasts during pregnancy and that placental CRH could induce the production of adrenocorticotropic hormone (ACTH) in humans. However, whether the same is true in rodent placenta remains ...

journal_title：Biochemical and biophysical research communications

authors： Wang H,Tsukada T,Shimada H,Sakata-Haga H,Iida Y,Zhang S,Shoji H,Hatta T

更新日期：2020-01-29 00:00:00

abstract：:The quiescent and proliferating status of the cell appears characterized by two different tRNA populations. The tRNA species changed both as relative percentage of total tRNA and in absolute concentration. The changes seem causally related to the proliferation status of the cell as tRNAs from proliferating hepatocytes...

journal_title：Biochemical and biophysical research communications

authors： Kanduc D

更新日期：1996-04-25 00:00:00

abstract：:Nitric oxide (NO) production is increased in the intestine and may contribute to intestinal injury in sepsis. However, the tissue expression of inducible NO synthase (iNOS) mRNA throughout the digestive tract and its relation with the mucosal damage after endotoxin challenge remain unknown. We therefore measured tissu...

journal_title：Biochemical and biophysical research communications

authors： Chen K,Inoue M,Okada A

更新日期：1996-07-25 00:00:00

abstract：:The cytoplasmic domain of the neural cell adhesion molecule (NCAM) contains multiple phosphorylation sites. We report here that in addition to serine and threonine residues a tyrosine of the NCAM180 isoform is phosphorylated as shown by phosphoamino acid analysis. Exchange of the only cytoplasmic tyrosine at position ...

journal_title：Biochemical and biophysical research communications

authors： Diestel S,Laurini C,Traub O,Schmitz B

更新日期：2004-09-10 00:00:00

abstract：:Autophosphorylation of phosphorylase kinase from rabbit skeletal muscle was stimulated by acidic phospholipids such as phosphatidic acid (PA), phosphatidylinositol, and phosphatidyl-serine. PA stimulated an initial velocity of autophosphorylation 3.8-fold. When fully autophosphorylated, about 11 mol of phosphate per t...

journal_title：Biochemical and biophysical research communications

authors： Negami AI,Sasaki H,Yamamura H

更新日期：1985-09-16 00:00:00

abstract：:In order to study the relationship between insulin like growth factor-II (IGF-II) and interleukin-8 (IL-8) that are upregulated in psoriasis, we monitored IL-8 expression in IGF-II-treated human keratinocytes and explored the signaling pathways of IL-8 expression by IGF-II. IGF-II increased the IL-8 mRNA and protein l...

journal_title：Biochemical and biophysical research communications

authors： Kim HJ,Byun SJ,Kim TY

更新日期：2004-04-23 00:00:00

abstract：:In this study we have continuously measured real-time production of nitric oxide (NO) in the isolated, perfused rat lung by using an NO monitor (model NO-501, Inter Medical Co., Nagoya, Japan) with an NO-selective resin microsensor. A stable NO response was obtained when the sensor was placed in the pulmonary artery o...

journal_title：Biochemical and biophysical research communications

authors： Wang D,Hsu K,Hwang CP,Chen HI

更新日期：1995-03-28 00:00:00

abstract：:Antigen-specific regulatory CD4(+) T cells have been described but there are few reports on regulatory CD8(+) T cells. We generated islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)-specific regulatory CD8(+) T cells from 8.3-NOD transgenic mice. CD8(+) T cells from 8.3-NOD splenocytes were...

journal_title：Biochemical and biophysical research communications

authors： Kishi M,Yasuda H,Abe Y,Sasaki H,Shimizu M,Arai T,Okumachi Y,Moriyama H,Hara K,Yokono K,Nagata M

更新日期：2010-03-26 00:00:00