Modulation of in vitro kidney cell growth by hepatic transfer RNAs.

abstract：:Adipose tissue is an active endocrine organ producing a variety of cytokines and chemokines, which may be involved in the deregulation of glucose and lipid homeostasis as well as in the inflammatory state observed in obesity. We have shown previously that differentiated human adipocytes secrete a variety of cytokines ...

journal_title：Biochemical and biophysical research communications

authors： Sell H,Dietze-Schroeder D,Eckardt K,Eckel J

更新日期：2006-05-12 00:00:00

abstract：:Ovarian progesterone secretion during the diestrus stage of the estrous cycle is produced by luteal cells derived from granulosa and thecal cells after the differentiation process that follows ovulation. Our results show that blockade of the preovulatory rise of ovarian ornithine decarboxylase (ODC), a key enzyme in p...

journal_title：Biochemical and biophysical research communications

authors： Bastida CM,Tejada F,Cremades A,Peñafiel R

更新日期：2002-04-26 00:00:00

abstract：:Heat stable enterotoxins (STs) are low molecular-weight peptides secreted by enterotoxigenic bacteria. One type of these enterotoxins (STa) induces intestinal secretion leading to acute diarrhea by binding to a membrane form of guanylate cyclase. We have isolated a cDNA from a human colonic cell line, T84, encoding fo...

journal_title：Biochemical and biophysical research communications

authors： Singh S,Singh G,Heim JM,Gerzer R

更新日期：1991-09-30 00:00:00

abstract：:The aim of the present study was to identify a high affinity InsP4 receptor in membranes from cerebellum or brain from several species. In samples obtained from sheep, beef, human and rat, a 42 kDa protein represents an Ins(1,3,4,5)P4 receptor, similar to the InsP4 receptor from pig cerebellum, which we have described...

journal_title：Biochemical and biophysical research communications

authors： Reiser G,Kunzelmann U,Hülser E,Stricker R,Hoppe J,Lottspeich F,Kalbacher H

更新日期：1995-09-05 00:00:00

abstract：:Astrocytic glycogen metabolism sustains neuronal activity but its impact on basal glutamatergic synaptic transmission is not clear. To address this issue, we have compared the effect of glycogen breakdown inhibition on miniature excitatory postsynaptic currents (mEPSCs) in rat hippocampal pure neuronal culture (PNC) a...

journal_title：Biochemical and biophysical research communications

authors： Mozrzymas J,Szczęsny T,Rakus D

更新日期：2011-01-14 00:00:00

abstract：:Membrane lipid peroxidation is known to produce various aldehydic compounds which cause a wide range of biological effects including heart disease, aging, and cancer. To investigate the effect of lipid peroxidation products on the expression of glutathione S-transferases (GSTs), which catalyze the conjugation of react...

journal_title：Biochemical and biophysical research communications

authors： Fukuda A,Nakamura Y,Ohigashi H,Osawa T,Uchida K

更新日期：1997-07-18 00:00:00

abstract：:The purpose of the present study is to characterize the ENaC-mediated Na+ absorption in human upper airway epithelia, nasal cavity, and paranasal sinus. To perform the purpose, we obtained epithelial cells from human nasal polyp (NP) and paranasal sinus mucosa (PSM) by endoscopic surgery. We measured the short-circuit...

journal_title：Biochemical and biophysical research communications

authors： Yasuda M,Niisato N,Miyazaki H,Iwasaki Y,Hama T,Dejima K,Hisa Y,Marunaka Y

更新日期：2007-10-26 00:00:00

abstract：:Effect of recombinant human interleukin-11 (rhIL-11) on the expression of transcripts encoding microsomal heme oxygenase (HO), the rate-limiting enzyme in heme catabolism, and haptoglobin (Hpt), a major acute-phase protein, were examined in human HepG2 hepatoma cells. Treatment of HepG2 cells with rhIL-11 elicited an ...

journal_title：Biochemical and biophysical research communications

authors： Fukuda Y,Sassa S

更新日期：1993-05-28 00:00:00

abstract：:Plants use specialized root outgrowths, termed root hairs, to enhance acquisition of nutrients and water, help secure anchorage, and facilitate interactions with soil microbiome. One of the major regulators of this process is GLABRA2 (GL2), a transcriptional repressor of root hair differentiation. However, regulation ...

journal_title：Biochemical and biophysical research communications

authors： Wu R,Citovsky V

更新日期：2017-07-01 00:00:00

abstract：:Expression of macrophage paraoxonase 2 (PON2), a cellular lactonase with anti-oxidant and anti-atherogenic properties, was shown to be upregulated under high oxidative stress. The aim of the present study was to analyze the relationship between the extent of cellular oxidative stress in J774A.1 macrophage and PON2 lac...

journal_title：Biochemical and biophysical research communications

authors： Shiner M,Fuhrman B,Aviram M

更新日期：2006-10-27 00:00:00

abstract：:N-Acetylglucosaminyltransferase I (GlcNAcT-I, EC 2.4.1.101) is the enzyme which initiates the formation of complex N-linked glycans in eukaryotes by transforming GlcNAc to the oligo-mannosyl acceptor Man(5)GlcNAc(2)-Asn. The enzymatic activity and the structure that is synthesised by this enzyme are found in animals a...

journal_title：Biochemical and biophysical research communications

authors： Bakker H,Lommen A,Jordi W,Stiekema W,Bosch D

更新日期：1999-08-11 00:00:00

abstract：:The calcium-sensing receptor (CaR) is a G protein-coupled receptor that plays key roles in extracellular calcium ion (Ca(2+)(o)) homeostasis by enabling parathyroid, kidney, and other cells to directly "sense" changes in Ca(2+)(o). In multiple myeloma-associated bone disease, myeloma cells could raise the level of Ca(...

journal_title：Biochemical and biophysical research communications

authors： Yamaguchi T,Yamauchi M,Sugimoto T,Chauhan D,Anderson KC,Brown EM,Chihara K

更新日期：2002-12-13 00:00:00

abstract：:We isolated and sequenced a cDNA clone corresponding to the entire coding sequence of rat liver lysosomal cathepsin D. The deduced amino acid sequence revealed that cathepsin D consists of 407 amino acid residues (Mr 44,608) and the 20 NH2-terminal residues seem to constitute a cleavable signal peptide after which 44 ...

journal_title：Biochemical and biophysical research communications

authors： Fujita H,Tanaka Y,Noguchi Y,Kono A,Himeno M,Kato K

更新日期：1991-08-30 00:00:00

abstract：:We generated a set of GFP-tagged chimeras between protein kinase D2 (PKD2) and protein kinase D3 (PKD3) to examine in live cells the contribution of their C-terminal region to their intracellular localization. We found that the catalytic domain of PKD2 and PKD3 can localize to the nucleus when expressed without other ...

journal_title：Biochemical and biophysical research communications

authors： Papazyan R,Rozengurt E,Rey O

更新日期：2006-04-14 00:00:00

abstract：:Two forms of human placental alkaline phosphatase have been purified to homogeneity utilizing high performance liquid chromatography. Both have the same amino acid composition but they differ in their carbohydrate substituents. Sequence data indicate that the two forms are identical for the first forty two residues fr...

journal_title：Biochemical and biophysical research communications

authors： Ezra E,Blacher R,Udenfriend S

更新日期：1983-11-15 00:00:00

abstract：:Osteoclasts which derive from hemopoietic cells are multinucleated cells responsible for bone resorption. We found that cyclopiazonic acid (CPA), thapsigargin (TG), and 2,5-di-(t-butyl)-1,4-hydroquinone (BHQ) induced osteoclast-like cell (OCL) formation in cocultures of mouse calvaria-derived stromal cells and hemopoi...

journal_title：Biochemical and biophysical research communications

authors： Takami M,Woo JT,Takahashi N,Suda T,Nagai K

更新日期：1997-08-08 00:00:00

abstract：:Mannoproteins (MPs) are a major component of yeast cell walls and consist of high levels of mannose in covalent complexes with proteins. MPs complexly enhance the immune system. We previously isolated a mutant yeast, K48L3, with a higher yield of MP from its cell wall than wild-type Saccharomyces cerevisiae, YPH499. W...

journal_title：Biochemical and biophysical research communications

authors： Yoon BH,Lee SM,Chang HI,Ha CH

更新日期：2019-11-19 00:00:00

abstract：:The characterization of a 20 kilodalton (20 kD) variant of rat growth hormone is reported. The 20 kD variant from rat pituitary gland extracts was identified on Western immunoblots of polyacrylamide gels. It was also shown that pituitary tissue maintained in culture secretes the 20 kD form. A rat growth hormone cDNA f...

journal_title：Biochemical and biophysical research communications

authors： Howland DS,Farrington MA,Taylor WD,Hymer WC

更新日期：1987-09-15 00:00:00

abstract：:A family of short interspersed repetitive elements (SINEs), designated mermaid, is present in the genomes of fish, amphibian and primates, but absent in the mouse genome. We have demonstrated that the sequences of the mermaid family are highly polymorphic in the zebrafish genome as in the human genome. We have also sh...

journal_title：Biochemical and biophysical research communications

authors： Shimoda N,Chevrette M,Ekker M,Kikuchi Y,Hotta Y,Okamoto H

更新日期：1996-03-07 00:00:00

abstract：:Cells of the monocyte series respond to follicle stimulating hormone (FSH) by poorly characterized mechanisms. We studied FSH-receptors (FSH-R) and FSH response in nontransformed human monocytes and in osteoclasts differentiated from these cells. Western blot and PCR confirmed FSH-R expression on monocytes or osteocla...

journal_title：Biochemical and biophysical research communications

authors： Robinson LJ,Tourkova I,Wang Y,Sharrow AC,Landau MS,Yaroslavskiy BB,Sun L,Zaidi M,Blair HC

更新日期：2010-03-26 00:00:00

abstract：:The exon/intron organization and the structure of the 5' flanking region of the human thyrotropin receptor gene (hTSH-R) were determined. The hTSH-R gene spans more than 60 kb and is split into ten exons. The extracellular domain is encoded by the first nine exons and part of the last exon, whereas the transmembrane a...

journal_title：Biochemical and biophysical research communications

authors： Gross B,Misrahi M,Sar S,Milgrom E

更新日期：1991-06-14 00:00:00

abstract：:In this study, we describe the identification and cloning of a novel member of the nuclear receptor superfamily. This orphan receptor, referred to as ROR gamma, belongs to the ROR/RZR subfamily. The open reading frame of ROR gamma encodes a protein of 560 amino acid residues with a predicted molecular mass of 63 kD. T...

journal_title：Biochemical and biophysical research communications

authors： Hirose T,Smith RJ,Jetten AM

更新日期：1994-12-30 00:00:00

abstract：:The cardioprotective effect of SUN 1165, a novel sodium channel blocker, was investigated on ischemic myocardium. Nineteen anesthetized dogs were subjected to 2 hours coronary occlusion, and divided into 2 groups. In the control group, physiological saline was infused. In the SUN 1165 group, 2 mg/kg of SUN 1165 was in...

journal_title：Biochemical and biophysical research communications

authors： Sugiyama S,Hanaki Y,Ogawa T,Hieda N,Taki K,Ozawa T

更新日期：1988-12-15 00:00:00

abstract：:Bcl-2 plays a pivotal role in the control of cell death and is down-regulated in trichosanthin (TCS)-induced cell apoptosis. Because Bcl-2 expression is regulated by the transcription factor cyclic AMP response element-binding protein (CREB), we investigated the role of CREB activation in TCS-induced Hela cells apopto...

journal_title：Biochemical and biophysical research communications

authors： Wang P,Yan H,Li JC

更新日期：2007-11-09 00:00:00

abstract：:4alpha-Carbinolamine dehydratase is a bifunctional protein involved in the regeneration of tetrahydrobiopterin during the hydroxylation of the aromatic amino acids. It is also a dimerization cofactor of HNF1 and therefore is believed to function as part of the hepatic gene transcription system. In view of the recent d...

journal_title：Biochemical and biophysical research communications

authors： Lei XD,Woodworth CD,Johnen G,Kaufman S

更新日期：1997-09-18 00:00:00

abstract：:Reactive oxygen species are known to induce strand breaks and/or base modifications in DNA. DNA strand breaks are associated with many pathologies and programmed cell death. We have examined the ability of the polyamines and their analogues to protect phi X-174 plasmid DNA from strand breakage induced by a oxygen-radi...

journal_title：Biochemical and biophysical research communications

authors： Ha HC,Yager JD,Woster PA,Casero RA Jr

更新日期：1998-03-06 00:00:00

abstract：:Activation of protein kinase C has been shown to be involved in the activation pathway of many cell types. Recently, a number of investigations have suggested that protein kinase C plays an essential role in T lymphocyte activation. The recent synthesis of the protein kinase inhibitors, H-7 and HA1004, have now made p...

journal_title：Biochemical and biophysical research communications

authors： Clark RB,Love JT Jr,Sgroi D,Lingenheld EG,Sha'afi RI

更新日期：1987-06-15 00:00:00

abstract：:Since conventional chemotherapy (gemcitabine and cisplatin) has marginal survival benefit in patients with advanced cholangiocarcinoma (CCA), an effective targeted therapeutic agent is urgently required. Activation of the PI3K/Akt/mTOR signaling pathway is frequently observed in CCA, and thus, PI3K and mTOR are promis...

journal_title：Biochemical and biophysical research communications

authors： Jang DK,Lee YG,Chan Chae Y,Lee JK,Paik WH,Lee SH,Kim YT,Ryu JK

更新日期：2020-09-03 00:00:00

abstract：:Chk2/hCds1, the human homolog of Saccharomyces cerevisiae Rad53p and Schizosaccharomyces pombe Cds1p, plays a critical role in the DNA damage checkpoint pathway. While several in vivo targets of Chk2 have been identified, the other target proteins of Chk2 responsible for multiple functions, such as cell cycle arrest, ...

journal_title：Biochemical and biophysical research communications

authors： Seo GJ,Kim SE,Lee YM,Lee JW,Lee JR,Hahn MJ,Kim ST

更新日期：2003-05-02 00:00:00

abstract：:Human leukemic HL60 cells are known to express NAD glycohydrolase (NADase) activity following differentiation into macrophage-like cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) or granulocyte-like cells by retinoic acid (RA) treatment. Recently, it was reported that 46 kDa human leukocyte antigen, CD38, expresse...

journal_title：Biochemical and biophysical research communications

authors： Han MK,An NH,Kim UH

更新日期：1995-08-15 00:00:00