Effect of retinoic acid on the acylation of phospholipids in granulocytes in vitro.

abstract：:Two P-450s from adult pig testis were purified to specific contents of 11.2 and 12.0 nmol P-450/mg protein and shown to have minimum molecular weights of 45,000 and 46,000, respectively. The absorption spectra were typical of P-450s. The P-450s were separated from the two fractions by CM-C50 Sephadex column chromatogr...

journal_title：Biochemical and biophysical research communications

authors： Kuwada M,Takizawa N,Sone Y

更新日期：1996-01-17 00:00:00

abstract：:Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1alpha subunit of the pyruvate dehydrogenase complex (PDC). Sequence analysis of cloned PDKs led to the proposal that they are mechanistically related to prokaryotic 2-component His-kinases. The reaction mechanism of protein His-kinases involves auto...

journal_title：Biochemical and biophysical research communications

authors： Mooney BP,David NR,Thelen JJ,Miernyk JA,Randall DD

更新日期：2000-01-19 00:00:00

abstract：:The human MEP1A gene encodes the meprin alpha subunit that consists of a protease domain conserved in the astacin family of metalloendopeptidases and several C-terminal interaction domains present in other proteins. Using the alpha subunit cDNA, we identified two clones from a human P1-derived artificial chromosome (P...

journal_title：Biochemical and biophysical research communications

authors： Jiang W,Beatty BG

更新日期：1999-07-22 00:00:00

abstract：:The nuclear lamina defines both structural and functional properties of the eukaryotic cell nucleus. Mutations in the LMNA gene, encoding A-type lamins, lead to a broad spectrum of diseases termed laminopathies. While different hypotheses have been postulated to explain disease development, there is still no unified v...

journal_title：Biochemical and biophysical research communications

authors： Sieprath T,Darwiche R,De Vos WH

更新日期：2012-05-18 00:00:00

abstract：:ZinT (B1973), previously known as YodA, was originally characterised as a cadmium-induced periplasmic protein under the regulation of Fur and SoxS. Here we describe a decrease in zinT transcript in response to elevated copper concentrations and the zinc and copper dependent phenotype of a DeltazinT strain. Cadmium sen...

journal_title：Biochemical and biophysical research communications

authors： Kershaw CJ,Brown NL,Hobman JL

更新日期：2007-12-07 00:00:00

abstract：:Intercellular adhesion between adjacent airway epithelial cells plays a critical role in maintaining the barrier function of the respiratory mucosa. In the current study, we examined the expression and interaction of cell surface adhesion molecules (E-cadherin, ICAM-1, and MUC1) and their intracellular binding partner...

journal_title：Biochemical and biophysical research communications

authors： Molock KE,Lillehoj EP

更新日期：2006-05-05 00:00:00

abstract：:Stimulation of prostaglandin production in C-9 rat liver cells by transforming growth factor (TGF)-alpha was synergistic with that of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). TGF-alpha and TPA synergized the release of radiolabelled compounds from [3H]arachidonic acid prelabelled C-9 cells. 1-Ol...

journal_title：Biochemical and biophysical research communications

authors： Levine L,Xiao DM,Worth N,Lilley WE

更新日期：1985-07-16 00:00:00

abstract：:Smooth muscle of guinea-pig taenia caecum was desensitized by treatment with 10(-4)M carbachol or 10(-4)M histamine for 30 min in Ca-free solution containing 2mM EGTA. Phosphatidylinositol turnover stimulated by carbachol was not reduced by desensitization with either carbachol or histamine, while the turnover stimula...

journal_title：Biochemical and biophysical research communications

authors： Hishinuma S,Uchida MK

更新日期：1989-07-31 00:00:00

abstract：:Ubiquitin C-terminal hydrolase-L3 (UCH-L3) is among the deubiquitinating enzymes (DUBs) that cleave ubiquitin (Ub) from Ub precursors or protein substrates. Many DUBs have been shown to participate in cancer progression in various tissues. However, the mechanism and role of UCH-L3 in carcinogenesis has largely been un...

journal_title：Biochemical and biophysical research communications

authors： Song HM,Lee JE,Kim JH

更新日期：2014-09-26 00:00:00

abstract：:In this study, we examined the endothelin (ET) receptor subtype involved in mitogenic signaling in human primary and metastatic melanoma cell lines. In a reverse transcriptase-polymerase chain reaction (RT-PCR) study, ET(B) mRNA expression in metastatic melanoma cells was decreased from that of primary melanoma. Only ...

journal_title：Biochemical and biophysical research communications

authors： Kikuchi K,Nakagawa H,Kadono T,Etoh T,Byers HR,Mihm MC,Tamaki K

更新日期：1996-02-27 00:00:00

abstract：:The PAX3 transcription factor is the key regulator of melanocyte development during embryogenesis and is also frequently found in melanoma cells. While PAX3 is known to regulate melanocyte differentiation, survival, proliferation and migration during development, it is not clear if its function is maintained in adult ...

journal_title：Biochemical and biophysical research communications

authors： Medic S,Rizos H,Ziman M

更新日期：2011-08-12 00:00:00

abstract：:To assess the relationship between cell proliferation and cell death, the mRNA accumulation of ornithine decarboxylase (ODC) and sulfated glycoprotein 2 (SGP-2) were measured in human peripheral blood lymphocytes (HPBL) 2-6 hours after stimulation with phytohemagglutinin (PHA). ODC is the rate limiting enzyme of polya...

journal_title：Biochemical and biophysical research communications

authors： Grassilli E,Bettuzzi S,Monti D,Ingletti MC,Franceschi C,Corti A

更新日期：1991-10-15 00:00:00

abstract：:Drosophila DLG (Discs Large Tumor Suppresser Protein) is a component of septate junctions, and disruption of its gene leads to over growth of imaginal discs. Homologs of Drosophila DLG recently isolated from mammalian tissue have been classified as members of the MAGUK (Membrane Associated GUanylate Kinase) superfamil...

journal_title：Biochemical and biophysical research communications

authors： Inagaki H,Maeda S,Lin KH,Shimizu N,Saito T

更新日期：1999-11-19 00:00:00

abstract：:[3H] Nitrendipine binding was partially blocked by the presence of tetrodotoxin in developing spinal cord neurons. In young cultures, 1 micron tetrodotoxin displaced 29% and 26% of [3H] nitrendipine binding from the high and low affinity binding sites, respectively. In one month old cultures, tetrodotoxin had no effec...

journal_title：Biochemical and biophysical research communications

authors： Litzinger MJ,Brenneman DE

更新日期：1984-11-14 00:00:00

abstract：:Retroviral growth requires as an obligatory step the integration of a DNA copy of the viral RNA into the genomic DNA of the host. Recombinant human immunodeficiency virus type I (HIV-1) integrase (IN) expressed in Escherichia coli efficiently catalyzes the overall in vitro integration reaction, namely, the processing ...

journal_title：Biochemical and biophysical research communications

authors： Carteau S,Mouscadet JF,Goulaouic H,Subra F,Auclair C

更新日期：1993-05-14 00:00:00

abstract：:Inhibitors of phenoloxidase were identified in pupae of the housefly, Musca domestica L. The phenoloxidase inhibitors were purified from final instar pupae of the housefly by a combination of ammonium sulfate fractionation, ion-exchange chromatography, gel filtration and reverse-phase high performance liquid chromatog...

journal_title：Biochemical and biophysical research communications

authors： Tsukamoto T,Ichimaru Y,Kanegae N,Watanabe K,Yamaura I,Katsura Y,Funatsu M

更新日期：1992-04-15 00:00:00

abstract：:The retinoblastoma gene product (pRB) has been known to contain a sequence-nonspecific DNA binding activity. It is unknown whether pRB can recognize and bind to specific DNA sequences. We have recently identified a rat genomic DNA fragment, termed REC11, which can interact with rat Cdc37-related protein (RCdc37). In t...

journal_title：Biochemical and biophysical research communications

authors： Ozaki T,Sakiyama S

更新日期：1996-09-04 00:00:00

abstract：:The optical spectrum of Sperm Whale myoglobin, which has been freshly reconstituted with iron protoporphyrin-IX, is shown to be different from that obtained from the native myoglobin, and from the reconstituted, incubated myoglobin (These last two have equivalent absorption spectra). The effect is immediately evident ...

journal_title：Biochemical and biophysical research communications

authors： Gebe JA,Peyton DH,Peyton JA

更新日期：1989-05-30 00:00:00

abstract：:In this paper we report the first comparative study of cold-adapted imidase (EC 3.5.2.2) from the fish (Oreochromis niloticus) liver and its thermophilic counterparts taken from pig liver and Escherichia coli (overexpressed recombinant hydantoinase from Agrobacterium radiobacter NRRL B1). Approximately 6000-fold purif...

journal_title：Biochemical and biophysical research communications

authors： Huang CY,Yang YS

更新日期：2003-12-12 00:00:00

abstract：:Clinical attention to gluten-related disorders, such as celiac disease and nonceliac gluten sensitivity, is on the rise. However, identifying the pathophysiological mechanisms of gluten-related disorders remains elusive. Gliadin, a component of gluten, is known to play a major role in gluten toxicity. Caenorhabditis e...

journal_title：Biochemical and biophysical research communications

authors： Lim SD,Min H,Youn E,Kawasaki I,Shim YH

更新日期：2018-09-10 00:00:00

abstract：:Antitrypsin was resolved into two pools by ion-exchange chromatography. Pool 2 contained three anodal isoinhibitors and an N-terminal sequence identical with the one found by others. Pool 1 contained, in addition to the anodal ones two cathodal isoinhibitors as well. The sequencing data of Pool 1 indicate that the cat...

journal_title：Biochemical and biophysical research communications

authors： Hercz A

更新日期：1985-04-16 00:00:00

abstract：:Intracellular cholesterol transfer to mitochondria, a bottleneck of adrenal and gonadal steroidogenesis, relies on the functioning of the steroidogenic acute regulatory protein (StAR, STARD1), for which many disease-associated mutations have been described. Despite significant progress in the field, the exact mechanis...

journal_title：Biochemical and biophysical research communications

authors： Sluchanko NN,Tugaeva KV,Maksimov EG

更新日期：2017-08-05 00:00:00

abstract：:The influence of experimental conditions during long-time (72 h) incubations of neonatal mouse calvaria on the measurement of prostaglandins was investigated. Incubations of the cultured calvaria were carried out in the presence and absence of stimulating agents of bone resorption, such as thrombin and parathyroid hor...

journal_title：Biochemical and biophysical research communications

authors： Leis HJ,Malle E,Hoffmann O,Klaushofer K,Fratzl-Zelman N,Koller K,Peterlik M

更新日期：1990-06-15 00:00:00

abstract：:The mouse gene locus Lsh/Ity/Bcg regulates macrophage activation for antimicrobial activity against intracellular pathogens. A candidate gene, designated natural resistance-associated macrophage protein gene (Nramp), recently isolated from a mouse pre-B cell cDNA library, encodes an integral membrane protein that has ...

journal_title：Biochemical and biophysical research communications

authors： Kishi F

更新日期：1994-11-15 00:00:00

abstract：:Vasectomy induces an immediate biophysical incompetence in epididymal spermatozoa in terms of the erroneous execution of membrane configuration processes, premature membrane melting and untimely protein gyration. Disturbances in the planned expression 'foreign proteins' and the possible 'swinging off' of these molecul...

journal_title：Biochemical and biophysical research communications

authors： Chatterjee S,Laloraya M,Kumar GP

更新日期：1993-12-15 00:00:00

abstract：:A mitosis inhibiting peptide pyroGlu-Glu-Asp-Ser-GlyOH has been isolated from mouse skin extracts. Both the biological and a synthetic peptide with the same structure reversibly inhibit epidermal mitoses in a curvilinear fashion after intraperitoneal injection. The two compounds are chromatographically identical. ...

journal_title：Biochemical and biophysical research communications

authors： Reichelt KL,Elgjo K,Edminson PD

更新日期：1987-08-14 00:00:00

abstract：:Leigh syndrome (LS) is an incurable, nearly always fatal, neurodegenerative, pediatric disorder that results from respiratory chain failure. The most common mitochondrial DNA (mtDNA) mutations that result in LS are m.8993T→C/G and m.9176T→C/G, which were previously found in several patients with early-onset Leigh synd...

journal_title：Biochemical and biophysical research communications

authors： Ronchi D,Bordoni A,Cosi A,Rizzuti M,Fassone E,Di Fonzo A,Servida M,Sciacco M,Collotta M,Ronzoni M,Lucchini V,Mattioli M,Moggio M,Bresolin N,Corti S,Comi GP

更新日期：2011-08-26 00:00:00

abstract：:Src homology 2 (SH2) domains mediate phosphotyrosine (pY)-dependent protein:protein interactions involved in signal transduction pathways. We have found that the SH2 domains of the 85-kDa alpha subunit (p85) of phosphatidylinositol 3-kinase (PI3 kinase) bind directly to the serine/threonine kinase A-Raf. In this repor...

journal_title：Biochemical and biophysical research communications

authors： Fang Y,Johnson LM,Mahon ES,Anderson DH

更新日期：2002-02-01 00:00:00

abstract：:Gastric epithelial cells (GES-1) stimulated by Helicobacter pylori (H. pylori) would affect the expression of related genes and induce the immune response of the cells. Abnormal methylation of DNA was one of the main causes. The aim of this study was to investigate phosphoinositol-3-kinase adaptor protein 1(PIK3AP1), ...

journal_title：Biochemical and biophysical research communications

authors： Zhang A,Yan S,Cao M,Wu D,Zhou J,Yu Z,Wu M,Liu Y,Lu S,Hu G,Zhao J

更新日期：2020-03-26 00:00:00

abstract：:Huntington's disease (HD) has been recently shown to have a horizontally transmitted, prion-like pathology. Thus, the migration of polyglutamine-containing aggregates to acceptor cells is important for the progression of HD. These aggregates contain glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which increases the...

journal_title：Biochemical and biophysical research communications

authors： Lazarev VF,Mikhaylova ER,Dutysheva EA,Suezov RV,Guzhova IV,Margulis BA

更新日期：2017-06-03 00:00:00