A 4 x 500 mm2 cloverleaf detector system for in vivo bone lead measurement.

Abstract:

:A 4 x 500 mm2 "cloverleaf" low energy germanium detector array has been assembled for the purpose of in vivo bone lead measurement through x-ray fluorescence. Using 109Cd as an exciting source, results are reported from a leg phantom simulating measurement of lead in a human tibia. For high activity (4.0-4.4 GBq) and low activity (0.18-0.19 GBq) sources, measurement results are reported for both the cloverleaf system and a conventional single detector system of equivalent surface area (2000 mm2). The mean uncertainty and reproducibility of measurement were both significantly improved for the cloverleaf system with a high activity 109Cd source. When using a source activity of 4.4 GBq, measurement of the phantom resulted in an average bone lead uncertainty of 0.79 microg/g and a reproducibility of 0.84 microg/g. These results represent the highest precision yet reported from a bone lead x-ray fluorescence system.

journal_name

Med Phys

journal_title

Medical physics

authors

Fleming DE,Mills CE

doi

10.1118/1.2436973

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

945-51

issue

3

eissn

0094-2405

issn

2473-4209

journal_volume

34

pub_type

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