Intensity-modulation radiotherapy using independent collimators: an algorithm study.

Abstract:

:The purpose of this work is to investigate algorithms for the delivery of intensity-modulated fields using independent collimators (IC). Two heuristic algorithms are proposed to calculate jaw-setting sequences for arbitrary 2D intensity distributions. The first algorithm is based on searching the whole intensity matrix to find the largest nonzero rectangular area as a segment while the second algorithm is to find a nonzero rectangular area as a segment which makes the complexity of the remaining intensity matrix minimum. After a sequence is obtained, the delivery order of all its segments is optimized with the technique of simulated annealing to minimize the total jaw-moving time. To evaluate these two algorithms, randomly generated intensity matrices and three clinical cases of different complexity have been tested, and the results have been compared with one algorithm proposed for MLC technique. It is shown that the efficiency of IC technique becomes increasingly lower than that of MLC technique, and the relative efficiency of two algorithms proposed here is related to machine dose rate and jaw speed. Assuming the prescribed dose is 200 cGY per fraction, machine dose rate is 250 MU/min, and jaw speed is 1.5 cm/s, the treatment can be delivered within about 20 min for all three cases with the first algorithm. The second algorithm requires longer delivery time under such assumptions. The delivery time can be further reduced through increasing machine dose rate and jaw speed, and developing more efficient algorithms. The use of IC for intensity-modulation radiotherapy has some potential advantages over other techniques.

journal_name

Med Phys

journal_title

Medical physics

authors

Dai JR,Hu YM

doi

10.1118/1.598794

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

2562-70

issue

12

eissn

0094-2405

issn

2473-4209

journal_volume

26

pub_type

杂志文章
  • Effect of patient support pads on image quality and dose in fluoroscopy.

    abstract::An investigation was performed of the changes in image quality and patient dose as a result of increasing filtration for fluoroscopy performed under automatic brightness control. Filtration was added either at the x-ray tube housing (i.e., scatter-free geometry) or adjacent to a tissue equivalent phantom simulating th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597906

    authors: Geiser WR,Huda W,Gkanatsios NA

    更新日期:1997-03-01 00:00:00

  • Mapping structural changes in breast tissue disease using x-ray scattering.

    abstract::Spread of invasive carcinoma throughout breast tissue is believed to occur at supramolecular levels, beyond the range of standard histopathology identification. Small angle x-ray scattering (SAXS) is capable of characterizing the structural properties of collagen and tissue found in the breast at the scale of tens to ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3147144

    authors: Sidhu S,Siu KK,Falzon G,Hart SA,Foxe JG,Lewis RA

    更新日期:2009-07-01 00:00:00

  • Dose homogeneity specification for reference dosimetry of nonstandard fields.

    abstract:PURPOSE:To investigate the sensitivity of the plan-class specific correction factor to dose distributions in composite nonstandard field dosimetry. METHODS:A cylindrical water-filled PMMA phantom was constructed at the center of which reference absorbed dose could be measured. Ten different TomoTherapy(®)-based IMRT f...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3669487

    authors: Chung E,Soisson E,Seuntjens J

    更新日期:2012-01-01 00:00:00

  • Experimental investigation on the accuracy of plastic scintillators and of the spectrum discrimination method in small photon fields.

    abstract:PURPOSE:To investigate the accuracy of output factor measurements using a commercial (Exradin W1, SI) and a prototype, "in-house" developed, plastic scintillation dosimeter (PSD) in small photon fields. METHODS:Repetitive detector-specific output factor OFdet measurements were performed in water (parallel to the CAX) ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12064

    authors: Papaconstadopoulos P,Archambault L,Seuntjens J

    更新日期:2017-02-01 00:00:00

  • 3D image-guided robotic needle positioning system for small animal interventions.

    abstract:PURPOSE:This paper presents the design of a micro-CT guided small animal robotic needle positioning system. In order to simplify the robotic design and maintain a small targeting error, a novel implementation of the remote center of motion is used in the system. The system has been developed with the objective of achie...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4771958

    authors: Bax JS,Waring CS,Sherebrin S,Stapleton S,Hudson TJ,Jaffray DA,Lacefield JC,Fenster A

    更新日期:2013-01-01 00:00:00

  • A new approach to CT pixel-based photon dose calculations in heterogeneous media.

    abstract::The effects of small cavities on dose in water and the dose in a homogeneous nonunit density medium illustrate that inhomogeneities do not act independently in photon dose perturbation, and serve as two constraints which should be satisfied by approximate methods of computed tomography (CT) pixel-based dose calculatio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595294

    authors: Wong JW,Henkelman RM

    更新日期:1983-03-01 00:00:00

  • Resin 90Y microsphere activity measurements for liver brachytherapy.

    abstract::The measurement of the radioactivity administered to the patient is one of the major components of 90Y microsphere liver brachytherapy. The activity of 90Y microspheres in a glass delivery vial was measured in a dose calibrator. The calibration value to use for 90Y in the dose calibrator was verified using an activity...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2731034

    authors: Dezarn WA,Kennedy AS

    更新日期:2007-06-01 00:00:00

  • X-ray-transmission computed tomography.

    abstract::The immediate goal of clinically based x-ray-transmission computed tomography (CT) is to provide a measurement of the x-ray linear attenuation coefficient in cross section with the ultimate goal of impacting on patient management and care. To do this with the accuracy needed for clinical goals requires the careful int...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.594381

    authors: McCullough EC,Payne JT

    更新日期:1977-03-01 00:00:00

  • Mixed model phase evolution for correction of magnetic field inhomogeneity effects in 3D quantitative gradient echo-based MRI.

    abstract:PURPOSE:In 3D gradient echo magnetic resonance imaging (MRI), strong field gradients B0macro are visually observed at air/tissue interfaces. At low spatial resolution in particular, the respective field gradients lead to an apparent increase in intravoxel dephasing, and subsequently, to signal loss or inaccurate R2* es...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12318

    authors: Fatnassi C,Boucenna R,Zaidi H

    更新日期:2017-07-01 00:00:00

  • A moving slanted-edge method to measure the temporal modulation transfer function of fluoroscopic systems.

    abstract::Lag in fluoroscopic systems introduces a frame-averaging effect that reduces measurements of image noise and incorrectly inflates measurements of the detective quantum efficiency (DQE). A correction can be implemented based on measurements of the temporal modulation transfer function (MTF). We introduce a method of me...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2919724

    authors: Friedman SN,Cunningham IA

    更新日期:2008-06-01 00:00:00

  • The water-equivalence of phantom materials for 90Sr-90Y beta particles.

    abstract::Intravascular brachytherapy requires that the dose be specified within millimeters of the source. High dose gradients near brachytherapy sources require that the source-detector distance be accurately known for dosimetry purposes. Solid phantoms can be designed to accommodate these stringent requirements. This study r...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1376176

    authors: Buckley LA,Thomadsen BR,DeWerd LA

    更新日期:2001-06-01 00:00:00

  • Technical Note: Compact three-tesla magnetic resonance imager with high-performance gradients passes ACR image quality and acoustic noise tests.

    abstract:PURPOSE:A compact, three-tesla magnetic resonance imaging (MRI) system has been developed. It features a 37 cm patient aperture, allowing the use of commercial receiver coils. Its design allows simultaneously for gradient amplitudes of 85 millitesla per meter (mT/m) sustained and 700 tesla per meter per second (T/m/s) ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4941362

    authors: Weavers PT,Shu Y,Tao S,Huston J 3rd,Lee SK,Graziani D,Mathieu JB,Trzasko JD,Foo TK,Bernstein MA

    更新日期:2016-03-01 00:00:00

  • Penetration quality measurement for standardization of radiographic image quality.

    abstract::Interchange or transfer of radiographic techniques through measurement of penetration quality is discussed. The usefulness of this achievement is verified using an aluminum step wedge. Also, the procedure described provides a method for performance evaluation of kVp compensation on diagnostic x-ray installations. ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594156

    authors: Lin PJ

    更新日期:1975-01-01 00:00:00

  • Estimation of organ doses from kilovoltage cone-beam CT imaging used during radiotherapy patient position verification.

    abstract:PURPOSE:The purpose of this study was to develop a practical method for estimating organ doses from kilovoltage cone-beam CT (CBCT) that can be performed with readily available phantoms and dosimeters. The accuracy of organ dose estimates made using the ImPACT patient dose calculator was also evaluated. METHODS:A 100 ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3476459

    authors: Hyer DE,Hintenlang DE

    更新日期:2010-09-01 00:00:00

  • Feasibility of a simple method of hybrid collimation for megavoltage grid therapy.

    abstract:PURPOSE:Megavoltage grid therapy is currently delivered with step-and-shoot multisegment techniques or using a high attenuation block with divergent holes. However, the commercial availability of grid blocks is limited, their construction is difficult, and step-and-shoot techniques require longer treatment times and ar...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4801902

    authors: Almendral P,Mancha PJ,Roberto D

    更新日期:2013-05-01 00:00:00

  • The dosimetric properties of an intraoperative radiation therapy applicator system for a Mevatron-80.

    abstract::An applicator system for intraoperative radiation therapy has been fabricated which does not require physical docking with the accelerator. A dosimetric study has been completed which documents the properties of this system for a variety of electron beam energies, applicator sizes, collimator settings, both primary an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596338

    authors: Nelson CE,Cook R,Rakfal S

    更新日期:1989-09-01 00:00:00

  • Minimizing image noise in on-board CT reconstruction using both kilovoltage and megavoltage beam projections.

    abstract::We studied a recently proposed aggregated CT reconstruction technique which combines the complementary advantages of kilovoltage (kV) and megavoltage (MV) x-ray imaging. Various phantoms were imaged to study the effects of beam orientations and geometry of the imaging object on image quality of reconstructed CT. It wa...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2768862

    authors: Zhang J,Yin FF

    更新日期:2007-09-01 00:00:00

  • Technical Note: Noninvasive mid-IR fiber-optic evanescent wave spectroscopy (FEWS) for early detection of skin cancers.

    abstract:PURPOSE:Melanoma is the most lethal of the three primary skin cancers, including also basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), which are less lethal. The accepted diagnosis process involves manually observing a suspicious lesion through a Dermascope (i.e., a magnifying glass), followed by a biopsy....

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14471

    authors: Basov S,Dankner Y,Weinstein M,Katzir A,Platkov M

    更新日期:2020-11-01 00:00:00

  • Measurement of LINAC 90 degrees head leakage radiation TVL values.

    abstract::One of the key components in modern LINAC room shielding design is the amount of 90 degrees head leakage radiation levels. With the general clinical acceptance of intensity-modulated radiation therapy (IMRT) technique, accurate knowledge of this quantity has become even more important. Measurement of 90 degrees head l...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2335489

    authors: Li Z,Mutic S,Low D

    更新日期:2006-09-01 00:00:00

  • Astigmatic single photon emission computed tomography imaging with a displaced center of rotation.

    abstract::A filtered backprojection algorithm is developed for single photon emission computed tomography (SPECT) imaging with an astigmatic collimator having a displaced center of rotation. The astigmatic collimator has two perpendicular focal lines, one that is parallel to the axis of rotation of the gamma camera and one that...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598325

    authors: Wang H,Smith MF,Stone CD,Jaszczak RJ

    更新日期:1998-08-01 00:00:00

  • X-ray imaging technique for in vitro tissue composition measurements using saline/iodine displacement: technique optimization.

    abstract::An in vitro radiographic technique which uses saline/iodine displacement has been developed to study the thickness of bone-equivalent and soft-tissue-equivalent materials within atherosclerotic plaques in arterial specimens which have been cut open longitudinally and laid flat. Results concerning the optimization of t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597916

    authors: Moreau M,Holdsworth DW,Fenster A

    更新日期:1997-01-01 00:00:00

  • Application of radiomics for the prediction of HPV status for patients with head and neck cancers.

    abstract:PURPOSE:To perform radiomic analysis of primary tumors extracted from pretreatment contrast-enhanced computed tomography (CE-CT) images for patients with oropharyngeal cancers to identify discriminant features and construct an optimal classifier for the characterization and prediction of human papilloma virus (HPV) sta...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13977

    authors: Bagher-Ebadian H,Lu M,Siddiqui F,Ghanem AI,Wen N,Wu Q,Liu C,Movsas B,Chetty IJ

    更新日期:2020-02-01 00:00:00

  • Soft-tissue detectability in cone-beam CT: evaluation by 2AFC tests in relation to physical performance metrics.

    abstract::Soft-tissue detectability in cone-beam computed tomography (CBCT) was evaluated via two-alternative forced-choice (2AFC) tests. Investigations included the dependence of detectability on radiation dose, the influence of the asymmetric three-dimensional (3D) noise-power spectrum (NPS) in axial and sagittal or coronal p...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2790586

    authors: Tward DJ,Siewerdsen JH,Daly MJ,Richard S,Moseley DJ,Jaffray DA,Paul NS

    更新日期:2007-11-01 00:00:00

  • SU-E-J-43: Autotuning Imaging Parameters in X-Ray Fluoroscopic Tracking for Dose Savings.

    abstract:PURPOSE:In fluoroscopy-guided clinical procedures that involve tracking objects over long treatment times, there is a need for reducing the amount of imaging dose delivered to the patient and the operating staff. In this study, we introduce a feedback metric to minimize tube current while maintaining a targeting precis...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734878

    authors: Siddique S,Fiume E,Jaffray D

    更新日期:2012-06-01 00:00:00

  • Combined kV and MV imaging for real-time tracking of implanted fiducial markers.

    abstract::In the presence of intrafraction organ motion, target localization uncertainty can greatly hamper the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT). To minimize the adverse dosimetric effect caused by tumor motion, a real-time knowledge of the tumor position is requ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2842072

    authors: Wiersma RD,Mao W,Xing L

    更新日期:2008-04-01 00:00:00

  • Dose sculpting with generalized equivalent uniform dose.

    abstract::With intensity-modulated radiotherapy (IMRT), a variety of user-defined dose distribution can be produced using inverse planning. The generalized equivalent uniform dose (gEUD) has been used in IMRT optimization as an alternative objective function to the conventional dose-volume-based criteria. The purpose of this st...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1897464

    authors: Wu Q,Djajaputra D,Liu HH,Dong L,Mohan R,Wu Y

    更新日期:2005-05-01 00:00:00

  • Analytical representation of head scatter factors for shaped photon beams using a two-component x-ray source model.

    abstract::An analytic representation proposed for the relative intensity distribution of the extra-focal source in a two-component x-ray source model serves as the basis for calculation. From this representation, a closed-form expression for head scatter factors defined on the central beam axis is derived by integrating over th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597494

    authors: Yu MK,Sloboda R

    更新日期:1995-12-01 00:00:00

  • Estimated spectrum of a 4-MV therapeutic beam.

    abstract::We have made a comparative investigation of the estimated spectra obtained by the Laplace transform analysis of the transmitted exposure data measured in an absorption study of a 4-MV x-ray beam. Four transform pair models currently used with this method have been evaluated. It has been determined that the Archer-Wagn...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595878

    authors: Ahuja SD,Steward PG,Roy TS,Slessinger ED

    更新日期:1986-05-01 00:00:00

  • An improved electron energy-loss straggling algorithm for Monte Carlo transport codes.

    abstract::The commonly used Blunck and Leisegang electron energy-loss distribution falls off too rapidly with increasing energy loss. Also, for large thicknesses and/or low-Z media, where their distribution should approach Landau's, it normalizes to 0.92 rather than 1.0, it overestimates the number of very small energy-loss eve...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595500

    authors: Weinhous MS,Nath R

    更新日期:1984-05-01 00:00:00

  • The effect of dose calculation uncertainty on the evaluation of radiotherapy plans.

    abstract::Monte Carlo dose calculations will potentially reduce systematic errors that may be present in currently used dose calculation algorithms. However, Monte Carlo calculations inherently contain random errors, or statistical uncertainty, the level of which decreases inversely with the square root of computation time. Our...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598916

    authors: Keall PJ,Siebers JV,Jeraj R,Mohan R

    更新日期:2000-03-01 00:00:00