Partial melting of the segment around pseudouridine in yeast 5S RNA.

abstract：:NDC1 is a transmembrane nucleoporin that is required for NPC assembly and nucleocytoplasmic transport. We show here that NDC1 directly interacts with the nucleoporin ALADIN, mutations of which are responsible for triple-A syndrome, and that this interaction is required for targeting of ALADIN to nuclear pore complexes...

journal_title：Biochemical and biophysical research communications

authors： Yamazumi Y,Kamiya A,Nishida A,Nishihara A,Iemura S,Natsume T,Akiyama T

更新日期：2009-11-06 00:00:00

abstract：:Advanced glycation end products (AGE) are involved in tissue damage and remodeling. This study investigated whether AGE could elicit inflammatory and fibrogenic reactions in fibroblast cell line MRC-5 cells via autocrine production of aldosterone and if nifedipine could block the AGE actions through mineralocorticoid ...

journal_title：Biochemical and biophysical research communications

authors： Matsui T,Takeuchi M,Yamagishi S

更新日期：2010-05-28 00:00:00

abstract：:Neuromedin B and neuromedin C are the novel mammalian bombesin-like peptides isolated from porcine spinal cord. We have developed highly specific and sensitive radioimmunoassays for neuromedin B and neuromedin C, and determined their regional distribution in rat central nervous system. Prior to measurements of the tis...

journal_title：Biochemical and biophysical research communications

authors： Minamino N,Kangawa K,Matsuo H

更新日期：1984-11-14 00:00:00

abstract：:Ligands of the glial cell line-derived neurotrophic factors (GDNF)-family are trophic factors for the development and survival of multiple cell types, however their effects on non-neuronal stem cells are unknown. We examined the action of neurturin on a candidate stem cell population isolated from adult skeletal muscl...

journal_title：Biochemical and biophysical research communications

authors： Vourc'h P,Lacar B,Mignon L,Lucas PA,Young HE,Chesselet MF

更新日期：2005-06-24 00:00:00

abstract：:Imipenem is often used to treat intensive care unit patients infected by Enterobacter aerogenes, but it is leading to an increasing number of antibiotic resistant strains. Clinical isolates and imipenem resistant variants presented a high level of resistance to beta-lactam antibiotic group and to chemically unrelated ...

journal_title：Biochemical and biophysical research communications

authors： Bornet C,Chollet R,Malléa M,Chevalier J,Davin-Regli A,Pagès JM,Bollet C

更新日期：2003-02-21 00:00:00

abstract：:Polycomb Group (PcG) genes encode proteins that form large multimeric and chromatin-associated complexes implicated in the stable repression of developmentally essential genes. HPH2, the Homo sapiens polyhomeotic homologue 2, functions as one of the subunits of PcG complex 1. In our study, SIAH-1, an E3 ligase, could ...

journal_title：Biochemical and biophysical research communications

authors： Wu H,Lin Y,Shi Y,Qian W,Tian Z,Yu Y,Huo K

更新日期：2010-07-02 00:00:00

abstract：:[2-14C]-trans-2-hexadecenoyl CoA (16:1) and [2-14C]-trans-2-cis-8,11,14-eicosatetraenoyl CoA (20:4) were chemically synthesized and employed as competitive substrates for the liver microsomal trans-2-enoyl CoA reductase component of the fatty acid chain elongation system. Both 7.5 microM and 15 microM 20:4 competitive...

journal_title：Biochemical and biophysical research communications

authors： Nagi MN,Cook L,Prasad MR,Cinti DL

更新日期：1986-10-15 00:00:00

abstract：:NO production in platelets has been followed by electrochemical detection. It was undetectable in unstimulated platelets and in thrombin or ADP-stimulated platelets, but dose-dependently stimulated by collagen. A production of 5 10(-19) mol/platelet was reached with 9 micrograms collagen. In collagen-stimulated platel...

journal_title：Biochemical and biophysical research communications

authors： Lantoine F,Brunet A,Bedioui F,Devynck J,Devynck MA

更新日期：1995-10-24 00:00:00

abstract：:The amino acid sequence of the rat 40S ribosomal subunit protein S18 was deduced from the sequence of nucleotides in a recombinant cDNA. S18 has 152 amino acids and has a molecular weight of 17,707. Hybridization of the cDNA to digests of nuclear DNA suggests that there are 10-13 copies of the S18 gene. The mRNA for t...

journal_title：Biochemical and biophysical research communications

authors： Chan YL,Paz V,Wool IG

更新日期：1991-08-15 00:00:00

abstract：:Angiotensin II (Ang II) and oxidized LDL (Ox-LDL) are risk factors for atherosclerosis, and both of them contribute to macrophage cholesterol accumulation, the hallmark of early atherosclerosis. As Ang II was shown to increase macrophage uptake of Ox-LDL, we investigated the effect of losartan, an Ang II receptor anta...

journal_title：Biochemical and biophysical research communications

authors： Hayek T,Aviram M,Heinrich R,Sakhnini E,Keidar S

更新日期：2000-07-05 00:00:00

abstract：:A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a cont...

journal_title：Biochemical and biophysical research communications

authors： Wakabayashi Y,Kikkawa Y,Matsumoto Y,Shinbo T,Kosugi S,Chou D,Furuya M,Jishage K,Noda T,Yonekawa H,Kominami R

更新日期：1997-05-08 00:00:00

abstract：:Chondromodulin-I (ChM-I) is a cartilage-specific glycoprotein that stimulates the growth of chondrocytes and inhibits the tube formation of endothelial cells. In the present study, we identified a novel ChM-I like molecule, designated ChM1L. Cloning of full length cDNAs of human, mouse, and rat ChM1L revealed that ChM...

journal_title：Biochemical and biophysical research communications

authors： Yamana K,Wada H,Takahashi Y,Sato H,Kasahara Y,Kiyoki M

更新日期：2001-02-02 00:00:00

abstract：:Preadipocytes constitutively express GATA-2 and GATA-3 that are required to halt the cells at the undifferentiated stage. However, we unexpectedly found that K-7174, a GATA-specific inhibitor, did not induce but rather inhibited differentiation of 3T3-L1 preadipocytes. It was associated with lack of lipid accumulation...

journal_title：Biochemical and biophysical research communications

authors： Shimada T,Hiramatsu N,Okamura M,Hayakawa K,Kasai A,Yao J,Kitamura M

更新日期：2007-11-16 00:00:00

abstract：:Since otoacoustic emissions were discovered, the old idea of a second (active) filter in the cochlea has been pursued with considerable dedication. In this contribution a concept explaining the action of the second filter is presented, which is derived from high-frequency resonance: The outer hair cells are excited wh...

journal_title：Biochemical and biophysical research communications

authors： Fritze W

更新日期：1996-06-14 00:00:00

abstract：:The thromboxane receptor has two alternatively spliced isoforms, alpha and beta, which differ only in sequences within the cytoplasmic C-terminal domain. Oxidative stress induced by H(2)O(2) in a COS-7 cell model results in stabilization of the thromboxane receptor beta isoform by translocation from the endoplasmic re...

journal_title：Biochemical and biophysical research communications

authors： Valentin F,Tippins JR,Field MC

更新日期：2005-04-15 00:00:00

abstract：:Dysregulation of long non-coding RNAs (lncRNA) have long been linked to the onset and development of colorectal cancer (CRC), yet the underlying mechanisms remain elusive. Small nucleolar RNA host gene 11 (SNHG11) is a novel lncRNA with few information about its role in development and progression of CRC. Here, we fou...

journal_title：Biochemical and biophysical research communications

authors： Huang W,Dong S,Cha Y,Yuan X

更新日期：2020-07-05 00:00:00

abstract：:Extracellular acidic pH-activated chloride channel I(Cl, acid), has been characterized in HEK 293 cells and mammalian cardiac myocytes. This study was designed to characterize I(Cl,acid) in human umbilical vein endothelial cells(HUVECs). The activation and deactivation of the current rapidly and repeatedly follows the...

journal_title：Biochemical and biophysical research communications

authors： Ma ZY,Zhang W,Chen L,Wang R,Kan XH,Sun GZ,Liu CX,Li L,Zhang Y

更新日期：2008-07-04 00:00:00

abstract：:Saccharomyces cerevisiae RecQ helicase (Sgs1) combines with DNA topoisomerase III (Top3) and RecQ-mediated genome instability 1 (Rmi1) to form an evolutionarily conserved complex that is required for processing homologous recombination intermediates and restarting collapsed replication forks. It was previously reporte...

journal_title：Biochemical and biophysical research communications

authors： Lai MS,Seki M,Tada S,Enomoto T

更新日期：2012-10-26 00:00:00

abstract：:The reactivity of human thioredoxin (HTR) was tested in several reactions. HTR was as efficient as E. coli or plant and algal thioredoxins when assayed with E. coli ribonucleotide reductase or for the reduction of insulin. On the other hand, HTR was poorly reduced by NADPH and the E. coli flavoenzyme NADPH thioredoxin...

journal_title：Biochemical and biophysical research communications

authors： Jacquot JP,de Lamotte F,Fontecave M,Schürmann P,Decottignies P,Miginiac-Maslow M,Wollman E

更新日期：1990-12-31 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) had been proved to be pivotal regulators in carcinogenesis. On the basis of competitive endogenous RNAs (ceRNAs) system, lncRNAs significantly expanded their regulating networks. In our research, we aimed to figure out the exact role of lncRNA HNF1A-AS1 in the pathogenesis of hepatocellu...

journal_title：Biochemical and biophysical research communications

authors： Liu Z,Wei X,Zhang A,Li C,Bai J,Dong J

更新日期：2016-05-13 00:00:00

abstract：:We have purified from beef liver an enzyme which decarbamoylates carbamoyl-hemoglobin and to a much lesser extent carbamoyl histones. Carbamoyl casein was a poor substrate while carbamoyl trypsin, fibrinogen and ovoalbumin were not affected. The optimal pH is 7.4. Addition of Mg++, Mn++ or Ca++ was without effect. On ...

journal_title：Biochemical and biophysical research communications

authors： Costell M,Grisolía S

更新日期：1985-04-16 00:00:00

abstract：:Advanced glomerulosclerosis, a common hallmark of chronic renal diseases (CRD) is believed to be irreversible, and it is thought that glomerular hyperfiltration and hypertrophy may participate in its pathogenesis. We demonstrate here that glomerulosclerosis is "reversible" in an animal model. We used nephrotic ICGN (n...

journal_title：Biochemical and biophysical research communications

authors： Mizuno-Horikawa Y,Mizuno S,Tamura S,Kurosawa T

更新日期：2001-06-15 00:00:00

abstract：:We generated two transgenic mice carrying the adenovirus type 12 E1 region genes under control of the human renin promoter, in which the E1A and E1B genes were expressed predominantly in the kidney. Interestingly, renal transcription of the gene for mouse renin was shown to be elevated at 28 and 40 folds as compared i...

journal_title：Biochemical and biophysical research communications

authors： Fukamizu A,Sagara M,Sugiyama F,Yagami K,Murakami K

更新日期：1994-02-28 00:00:00

abstract：:An 18-kDa lectin, with an N-terminal sequence displaying slight similarity to some lectins and fungal immunomodulatory proteins, was isolated from the mushroom Ganoderma capense (Lloyd) Teng. It exhibited more potent mitogenic activity than that of concanavalin A toward mouse splenocytes, and antiproliferative activit...

journal_title：Biochemical and biophysical research communications

authors： Ngai PH,Ng TB

更新日期：2004-02-20 00:00:00

abstract：:CRACR2A protein is described in T cells as an EF-hand-containing modulator of calcium-release-activated calcium (CRAC) channels. Here we sought relevance to calcium entry of endothelial cells. Unexpectedly, short interfering RNA designed to deplete CRACR2A had no effect on CRAC channels in endothelial cells but reduce...

journal_title：Biochemical and biophysical research communications

authors： Wilson LA,McKeown L,Tumova S,Li J,Beech DJ

更新日期：2015-01-02 00:00:00

abstract：:Platelet-derived growth factor (PDGF)-BB elicits a migratory response including reorganization of the actin cytoskeleton in different cell types. Here we have investigated the effects of PDGF-BB stimulation on beta(1) integrin containing focal adhesions in human diploid fibroblasts adhered to collagen type I. Stimulat...

journal_title：Biochemical and biophysical research communications

authors： Ahlén K,Ring P,Tomasini-Johansson B,Holmqvist K,Magnusson KE,Rubin K

更新日期：2004-01-30 00:00:00

abstract：:The main transport mechanism of reabsorption of sodium bicarbonate and fluid in the renal proximal tubules involves Na(+)/H(+) exchanger 3 (NHE3), which is acutely and chronically downregulated by parathyroid hormone (PTH). Although PTH is known to exert an inhibitory effect on NHE3 expression and transcription, the m...

journal_title：Biochemical and biophysical research communications

authors： Neri EA,Bezerra CN,Queiroz-Leite GD,Polidoro JZ,Rebouças NA

更新日期：2015-06-12 00:00:00

abstract：:Activated botulinum D toxin ADP-ribosylates a 22 kDa molecular weight protein in homogenates obtained by sonication of a suspension of rabbit peritoneal neutrophils. The ADP-ribosylation catalyzed by activated botulinum D toxin is inhibited in homogenates obtained from cells pretreated with the toxin, suggesting that ...

journal_title：Biochemical and biophysical research communications

authors： Mege JL,Volpi M,Becker EL,Sha'afi RI

更新日期：1988-04-29 00:00:00

abstract：:A better understanding of cell biology and cell-cell interactions requires three-dimensional (3-D) culture systems that more closely represent the natural structure and function of tissues in vivo. Here, we present a novel device that provides an environment for routine 3-D cell growth in vitro. We have developed a th...

journal_title：Biochemical and biophysical research communications

authors： Bokhari M,Carnachan RJ,Cameron NR,Przyborski SA

更新日期：2007-03-23 00:00:00

abstract：:BALB/c mice were immunized with rIGF-II receptors purified from 18-54, SF cells by chromatography of solubilized receptors over agarose-immobilized rIGF-II. Two fusions of splenic lymphocytes with FO mouse myeloma cells yielded 27 stable hybrids which were positive by ELISA. Cloning of seven of these hybrids yielded 3...

journal_title：Biochemical and biophysical research communications

authors： Rosenfeld RG,Pham H

更新日期：1987-07-31 00:00:00