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Genetic and physical delineation of the region of the mouse deafness mutation shaker-2.

Abstract：

:A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a contig consisting of 21 BAC clones across an approximately 700-kb region of sh-2. This covers the entire nonrecombinant region of sh-2 and is therefore useful to facilitate the identification of genes in the sh-2 region.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Wakabayashi Y,Kikkawa Y,Matsumoto Y,Shinbo T,Kosugi S,Chou D,Furuya M,Jishage K,Noda T,Yonekawa H,Kominami R

doi

10.1006/bbrc.1997.6595

subject

Has Abstract

pub_date

1997-05-08 00:00:00

pages

107-10

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(97)96595-5

journal_volume

234

pub_type

杂志文章

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