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Intracellular location of polyamines associated to red blood cells.

Abstract：

:The polyamines associated to human erythrocytes from healthy donors are mainly localized intracellularly. In fact chromatography of the erythrocytes on a resin which has a high affinity and capacity for polyamines does not affect the amount of polyamines associated to the erythrocytes. The low ability of spermine to adsorb to the external surface of erythrocytes at physiological ionic strength is suggested also by studies conducted with sealed ghosts. Also erythrocytes from patients with hematological and dermatological diseases which contain increased levels of polyamines show an intracellular location of these amines.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Tadolini B,Hakim G,Orlandini G,Casti A

doi

10.1016/0006-291x(86)90400-6

subject

Has Abstract

pub_date

1986-02-13 00:00:00

pages

1365-71

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(86)90400-6

journal_volume

134

pub_type

杂志文章

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