当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Identification and gene structure of a novel human PLZF-related transcription factor gene, TZFP.

Identification and gene structure of a novel human PLZF-related transcription factor gene, TZFP.

Abstract：

:A novel cDNA clone was identified through yeast two-hybrid experiments. Following cross-examination between the cDNA clones, EST clones, and the cosmid clone, we could digitally assemble a new zinc finger transcription factor gene. This predicted gene has a cDNA size of about 1960 bp and is translated into a 487-amino-acid protein. According to database analysis, this gene contains three C2H2 zinc finger motifs and is highly related to human PLZF (promyelocytic leukemia zinc finger protein). The full-length coding region of the gene was isolated, and its sequences were confirmed by DNA sequencing. Interestingly, one splicing variant lacking exon III was also identified. Northern blot analysis revealed that this gene is mainly expressed in human testis. In conclusion, we have identified a new member of the PLZF zinc finger protein family, the testis zinc finger protein (TZFP), which is mainly expressed in testis tissue.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Lin W,Lai CH,Tang CJ,Huang CJ,Tang TK

doi

10.1006/bbrc.1999.1594

subject

Has Abstract

pub_date

1999-11-02 00:00:00

pages

789-95

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006291X99915942

journal_volume

264

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Clonorchis sinensis-derived total protein attenuates airway inflammation in murine asthma model by inducing regulatory T cells and modulating dendritic cell functions.

    abstract：:Asthma is characterized by Th2-mediated inflammation, resulting in airway hyperresponsiveness (AHR) through airway remodeling. Recent epidemiological and experimental reports have suggested an inverse relationship between the development of allergy and helminth infections. Infection by Clonorchis sinensis, a liver flu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.03.102

    authors： Jeong YI,Kim SH,Ju JW,Cho SH,Lee WJ,Park JW,Park YM,Lee SE

    更新日期：2011-04-22 00:00:00

  • Glucose regulation of CDK7, a putative thiol related gene, in experimental diabetic nephropathy.

    abstract：:We previously described the identification of the 3'end of an unknown gene CDK7 using differential display which appeared to be up-regulated in diabetic kidneys [R.A. Page, C.A. Morris, J.D. Williams, C.J. von Ruhland, A.N. Malik, Isolation of diabetes-associated kidney genes using differential display, Biochem. Bioph...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.03.132

    authors： Malik AN,Rossios C,Al-Kafaji G,Shah A,Page RA

    更新日期：2007-05-25 00:00:00

  • Growth hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I.

    abstract：:Gene-recombinant human growth hormone (rhGH) elicited a dose-dependent stimulation of the proliferation of osteoblast-like cells (OB), when grown in strictly serum-free longterm cultures. A half-maximal effect was observed at concentrations of 15-20 ng/ml and the maximal stimulation was 160% of hormone-free controls. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(88)90570-0

    authors： Ernst M,Froesch ER

    更新日期：1988-02-29 00:00:00

  • Morphine-mimetic anti-paratypic antibodies: cross-reactive properties.

    abstract：:Polyclonal, anti-idiotypic, rabbit antibodies have been raised against four murine monoclonal anti-morphine Fab fragments. The antibody preparations, after affinity purification, have been shown to contain an anti-paratypic fraction which reversibly inhibits morphine binding to the anti-morphine antibodies and to cell...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)90458-4

    authors： Glasel JA,Pelosi LA

    更新日期：1986-05-14 00:00:00

  • Histamine H2 receptor mediated dual signaling: mapping of structural requirements using beta2 adrenergic chimeric receptors.

    abstract：:Previously we demonstrated that the histamine H2 receptor can activate both the adenylate cyclase and phosphoinositide/protein kinase (PKC) signaling pathways. Although dual coupling occurs via separate GTP-dependent mechanisms the structural components of the H2 receptor directing differential signaling have not been...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3507

    authors： Wang LD,Gantz I,Butler K,Hoeltzel M,Del Valle J

    更新日期：2000-09-24 00:00:00

  • Identification of the metal associated with the insulin degrading enzyme.

    abstract：:Insulin degrading enzyme (IDE) is a thiol-dependent metalloendoprotease that is responsible for initiation of cellular insulin degradation. However, its exact mode of action and the factors controlling it are poorly understood. Since IDE is a metal requiring enzyme, we have examined which metal(s) is(are) endogenously...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)92094-z

    authors： Ebrahim A,Hamel FG,Bennett RG,Duckworth WC

    更新日期：1991-12-31 00:00:00

  • Potent inhibition of tau fibrillization with a multivalent ligand.

    abstract：:Small-molecule inhibitors of tau fibrillization are under investigation as tools for interrogating the tau aggregation pathway and as potential therapeutic agents for Alzheimer's disease. Established inhibitors include thiacarbocyanine dyes, which can inhibit recombinant tau fibrillization in the presence of anionic s...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.08.166

    authors： Honson NS,Jensen JR,Darby MV,Kuret J

    更新日期：2007-11-09 00:00:00

  • In vivo delivery of small interfering RNA targeting brain capillary endothelial cells.

    abstract：:Brain capillary endothelial cells (BCECs) play an important role in blood-brain barrier (BBB) functions and pathophysiologic mechanisms in brain ischemia and inflammation. We try to suppress gene expression in BCECs by intravenous application of small interfering RNA (siRNA). After injection of large dose siRNA with h...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.11.173

    authors： Hino T,Yokota T,Ito S,Nishina K,Kang YS,Mori S,Hori S,Kanda T,Terasaki T,Mizusawa H

    更新日期：2006-02-03 00:00:00

  • Anti-apoptotic peptides protect against radiation-induced cell death.

    abstract：:The risk of terrorist attacks utilizing either nuclear or radiological weapons has raised concerns about the current lack of effective radioprotectants. Here it is demonstrated that the BH4 peptide domain of the anti-apoptotic protein Bcl-xL can be delivered to cells by covalent attachment to the TAT peptide transduct...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.01.180

    authors： McConnell KW,Muenzer JT,Chang KC,Davis CG,McDunn JE,Coopersmith CM,Hilliard CA,Hotchkiss RS,Grigsby PW,Hunt CR

    更新日期：2007-04-06 00:00:00

  • Swings in blood glucose levels accelerate atherogenesis in apolipoprotein E-deficient mice.

    abstract：:The aim of this study was to investigate the effect of fluctuations in blood glucose levels on atherogenesis. Apolipoprotein (apo) E-deficient mice fed maltose twice daily were used as a model of repetitive postprandial glucose spikes. We investigated the number of macrophages adherent to the endothelium and the area ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.04.118

    authors： Mita T,Otsuka A,Azuma K,Uchida T,Ogihara T,Fujitani Y,Hirose T,Mitsumata M,Kawamori R,Watada H

    更新日期：2007-07-06 00:00:00

  • Characterization of a cancer cell line that expresses a splicing variant form of 53BP1: separation of checkpoint and repair functions in 53BP1.

    abstract：:53BP1 plays important roles in checkpoint signaling and repair for DNA double-strand breaks. We found that a colon cancer cell line, SW48, expressed a splicing variant form of 53BP1, which lacks the residues corresponding to exons 10 and 11. Activation of ATM and phosphorylation of ATM and ATR targets occurred in SW48...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.09.022

    authors： Iwabuchi K,Matsui T,Hashimoto M,Matsumoto Y,Kurihara T,Date T

    更新日期：2008-11-21 00:00:00

  • Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74.

    abstract：:The receptor for calcitonin gene-related peptide (CGRP) has been the target for the development of novel small molecule antagonists for the treatment of migraine. Two such antagonists, BIBN4096BS and MK-0974, have shown great promise in clinical trials and hence a deeper understanding of the mechanism of their interac...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.11.076

    authors： Miller PS,Barwell J,Poyner DR,Wigglesworth MJ,Garland SL,Donnelly D

    更新日期：2010-01-01 00:00:00

  • Brassinosteroid-induced CO(2) assimilation is associated with increased stability of redox-sensitive photosynthetic enzymes in the chloroplasts in cucumber plants.

    abstract：:Brassinosteroids (BRs) play important roles in plant growth, development, photosynthesis and stress tolerance; however, the mechanism underlying BR-enhanced photosynthesis is currently unclear. Here, we provide evidence that an increase in the BR level increased the quantum yield of PSII, activities of Rubisco activas...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.08.100

    authors： Jiang YP,Cheng F,Zhou YH,Xia XJ,Mao WH,Shi K,Chen ZX,Yu JQ

    更新日期：2012-09-28 00:00:00

  • 2'-Amino-2'-deoxyguanosine is a cofactor for self-splicing in group I catalytic RNA.

    abstract：:In investigations on self-splicing in the group I intron of the pre-mRNA from the nrdB gene of bacteriophage T4 it was found that 2'-amino-2'-deoxyguanosine can replace guanosine as cofactor. This is the first guanosine-analogue with a modification in the 2'-position and substantial activity in a group I self-splicing...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)90560-8

    authors： Strömberg R,Hahne S,Sjögren AS,Sjöberg BM

    更新日期：1992-03-16 00:00:00

  • Desmoglein genes are up-regulated in the pk mutant mouse.

    abstract：:Plucked (pk) is an autosomal recessive mouse mutation with a hair phenotype that arose spontaneously in the DBA/2J strain. Histological studies indicate that adult pk mutant mice lose truncal hair because of the scarring of follicles due to an apparent obstruction of the outward movement of the hair shaft within the f...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.11.136

    authors： Luo J,Zhang L,Stenn K,Prouty S,Parimoo S

    更新日期：2005-02-04 00:00:00

  • An aortic spontaneously active phosphatase dephosphorylates myosin and inhibits actin-myosin interaction.

    abstract：:Actin-myosin interaction in aortic actomyosin reportedly requires phosphorylation of the 20,000 dalton myosin light chains. A spontaneously active phosphatase which dephosphorylates phosphorylase a and isolated phosphorylated cardiac myosin light chains was extracted from bovine aortic smooth muscle. This enzyme, when...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)91385-2

    authors： Di Salvo J,Gifford D,Bialojan C,Rüegg JC

    更新日期：1983-03-29 00:00:00

  • Klenow exo-, as opposed to exo+, traverses through G-G:C triplex by melting G-G base pairs.

    abstract：:G-G base-paired hairpin DNA structures on template strands offer potential "road-blocks" to a traversing polymerase. Klenow polymerase (exo+) pauses while replicating through G-G base-paired hairpin DNA due to the generation of G-G:C triplex. However, exonuclease-deficient Klenow traverses through de novo generated G-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)00749-0

    authors： Ramanathan S,Chary KV,Rao BJ

    更新日期：2002-07-19 00:00:00

  • A mechanism for oxygen exchange between ligated oxometalloporphinates and bulk water.

    abstract：:Oxygen exchange between high-valent metal-oxo complexes and bulk water has been monitored for nonligated model porphyrins (hemin, FeTDCPPS, MnTMPyP) and the axially ligated microperoxidase-8 (MP-8). Exchange extents up to 90% were measured for MP-8 in spite of the presence of an axial histidine ligand and accompanied ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2809

    authors： Primus JL,Teunis K,Mandon D,Veeger C,Rietjens IM

    更新日期：2000-06-07 00:00:00

  • Molecular cloning and developmental expression of plakophilin 2 in zebrafish.

    abstract：:Armadillo proteins are involved in providing strength and support to cells and tissues, nuclear transport, and transcriptional activation. In this report, we describe the identification and characterisation of the cDNA of the desmosomal armadillo protein plakophilin 2 in zebrafish. The 2448bp coding sequence encodes a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.12.106

    authors： Moriarty MA,Martin ED,Byrnes L,Grealy M

    更新日期：2008-02-29 00:00:00

  • Enterococcus faecalis lipoteichoic acid regulates macrophages autophagy via PI3K/Akt/mTOR pathway.

    abstract：:Enterococcus faecalis (E. faecalis) infection is considered an important etiological factor for the development of persistent apical periodontitis (PAP), but the exact mechanisms of autophagy between E. faecalis and immune cells remain unknown. In this study, we elucidated how E. faecalis lipoteichoic acid (LTA) is as...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.03.109

    authors： Lin D,Gao Y,Zhao L,Chen Y,An S,Peng Z

    更新日期：2018-04-15 00:00:00

  • Maillard reaction-like lysine modification by a lipid peroxidation product: immunochemical detection of protein-bound 2-hydroxyheptanal in vivo.

    abstract：:2-Hydroxyheptanal (2-HH) is one of the reactive aldehyde species generated during the peroxidation of n-6 polyunsaturated fatty acids, such as linoleic and arachidonic acids. Analogous to the Maillard reaction of reducing sugars, 2-HH readily reacts with lysine epsilon-amino groups. In the present study, to define the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)01412-8

    authors： Itakura K,Furuhata A,Shibata N,Kobayashi M,Uchida K

    更新日期：2003-08-29 00:00:00

  • MicroRNA-21 accelerates hepatocyte proliferation in vitro via PI3K/Akt signaling by targeting PTEN.

    abstract：:MicroRNAs (miRNAs) are involved in controlling hepatocyte proliferation during liver regeneration. In this study, we established the miRNAs-expression patterns of primary hepatocytes in vitro under stimulation of epidermal growth factor (EGF), and found that microRNA-21 (miR-21) was appreciably up-regulated and peaked...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.12.047

    authors： Yan-nan B,Zhao-yan Y,Li-xi L,jiang Y,Qing-jie X,Yong Z

    更新日期：2014-01-17 00:00:00

  • Neuroprotective effects of memantine via enhancement of autophagy.

    abstract：INTRODUCTION:Chemical intervention of autophagy has been investigated in clinical trials for various age-related conditions such as sarcopenia and neurodegeneration. However, at present, no autophagy inducer has been established as a disease-modifying agent against neurodegenerative diseases. METHODS:We screened a lib...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.08.025

    authors： Hirano K,Fujimaki M,Sasazawa Y,Yamaguchi A,Ishikawa KI,Miyamoto K,Souma S,Furuya N,Imamichi Y,Yamada D,Saya H,Akamatsu W,Saiki S,Hattori N

    更新日期：2019-10-08 00:00:00

  • Identification of anti-TNFalpha peptides with consensus sequence.

    abstract：:Phage displayed peptide library was used to select tumor necrosis factor alpha (TNFalpha) binding peptides. After three sequential rounds of biopanning, some linear TNFalpha-binding peptides were identified from a 12-mer peptide library. A consensus sequence (L/M)HEL(Y/F)(L/M)X(W/Y/F), where X might be variable residu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.09.141

    authors： Zhang J,Zheng L,Zhao A,Gao B,Liu NL,Wang F,Dong J,Xin ZT,Shao NS,Wang HX,Xue YN

    更新日期：2003-10-31 00:00:00

  • Topoisomerase I and ATP activate cDNA synthesis of human immunodeficiency virus type 1.

    abstract：:Replication of human immunodeficiency virus type 1 (HIV-1) is regulated at reverse transcription. Cellular topoisomerase I has been reported to be carried into HIV-1 virions and enhance cDNA synthesis in vitro, suggesting that topoisomerase I expressed in virus producer cells regulates reverse transcription. Here, by ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/S0006-291X(02)00503-X

    authors： Takahashi H,Sawa H,Hasegawa H,Shoya Y,Sata T,Hall WW,Nagashima K,Kurata T

    更新日期：2002-06-07 00:00:00

  • Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells.

    abstract：:Pyrrolidine dithiocarbamate (PDTC) is a metal chelating compound that can exert either pro-oxidant or antioxidant effects in different situations. Several studies demonstrate that it can inhibit cyclooxygenase-2 (COX-2) expression, which may be due to its antioxidant activity. Here, we found that PDTC rather increased...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)02430-0

    authors： Lee JE,Kim KM,Cho JW,Suh SI,Suh MH,Kwon TK,Park JW,Bae JH,Song DK,Cho CH,Bae I,Baek WK

    更新日期：2002-10-25 00:00:00

  • Increased free-cystine content of fibroblasts cultured from patients with cystinosis.

    abstract：:The presence of a significantly increased content of free-cystine in skin fibroblasts from both homozygotes and heterozygotes for cystinosis emphasizes the central role of cystine in this disease, even though the primary defect responsible for cystine accumulation is yet to be determined. The studies described in this...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(67)90516-5

    authors： Schneider JA,Rosenbloom FM,Bradley KH,Seegmiller JE

    更新日期：1967-11-30 00:00:00

  • Paradoxical augmentation of (-)Bay K 8644-induced calcium influx by nitrendipine.

    abstract：:(-)Bay K 8644 produced a concentration-dependent contraction of porcine coronary artery rings with the maximal contraction at 10(-6) M. Pretreatment of the rings with 10(-6) M nitrendipine inhibited (-)Bay K 8644-induced contraction, while pretreatment with 10(-8) M nitrendipine potentiated the contraction elicited by...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91068-0

    authors： Miwa K,Schwartz A

    更新日期：1987-10-14 00:00:00

  • Characterization of fibrillation process of alpha-synuclein at the initial stage.

    abstract：:alpha-Synuclein is the major component of the filamentous Lewy bodies and Lewy-related neurites, neuropathological hallmarks of Parkinson's disease. Although numerous studies on alpha-synuclein fibrillation have been reported, the molecular mechanisms of aggregation and fibrillation at the initial stage are still uncl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.02.127

    authors： Tashiro M,Kojima M,Kihara H,Kasai K,Kamiyoshihara T,Uéda K,Shimotakahara S

    更新日期：2008-05-09 00:00:00

  • Enzymic and nonenzymic mono ADP-ribosylation of proteins in skeletal muscle.

    abstract：:The acceptors of endogenously catalyzed monoADP-ribosylation in the cell free extract from rat skeletal muscle was searched. The main acceptor proteins in particulate were electrophoretically 52, 80, 100, and greater than 200 kDa proteins in the presence of SDS, while that in cytosol were 36 and 39 kDa proteins. Altho...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)92329-2

    authors： Tanaka Y,Yoshihara K,Kamiya T

    更新日期：1989-09-15 00:00:00