A screening primer: basic principles, criteria, and pitfalls of screening with comments on colorectal carcinoma.

abstract：BACKGROUND:The presence of laryngopharyngeal reflux disease is controversial when abnormal sensation of the laryngopharynx is felt without heartburn. GOALS:The aims of this study were to investigate the relationship between abnormal sensation of the laryngopharynx and gastroesophageal reflux, and to elucidate the path...

journal_title：Journal of clinical gastroenterology

authors： Wada T,Sasaki M,Kataoka H,Ogasawara N,Kanematsu T,Tanida S,Nojiri S,Ando T,Okochi M,Joh T

更新日期：2009-03-01 00:00:00

abstract：:Associations between diverticular disease of the colon and the colorectal cancer has been studied for >60 years. Observational, cross-sectional, and case-control studies as well as large population-based studies gave conflicting results and association was not fully proven. Obtaining the proof was difficult because bo...

journal_title：Journal of clinical gastroenterology

authors： Regula J

更新日期：2016-10-01 00:00:00

abstract：GOALS:To describe current hepatitis C virus (HCV) treatment practices in the United States and identify physician characteristics associated with the use of first generation direct-acting antivirals (DAAs). BACKGROUND:HCV treatment practice patterns have not been assessed after the introduction of DAA, which are now c...

journal_title：Journal of clinical gastroenterology

authors： Chen EY,Lee WM,Hynan LS,Singal AG

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Tormentil extracts (TE) have antioxidative properties and are used as a complementary therapy for chronic inflammatory bowel disease. In individual patients with ulcerative colitis (UC) positive effects have been observed. GOALS:To assess the safety, pharmacology, and clinical effects of different doses of ...

journal_title：Journal of clinical gastroenterology

authors： Huber R,Ditfurth AV,Amann F,Güthlin C,Rostock M,Trittler R,Kümmerer K,Merfort I

更新日期：2007-10-01 00:00:00

abstract：:Spontaneous umbilical fistula developed in two young women with Crohn's disease. This peculiar complication of Crohn's disease has been rarely reported. In view of the complete closure of the fistulas with medical treatment, we recommended conservative medical management, at least initially, in such patients. ...

journal_title：Journal of clinical gastroenterology

authors： Veloso FT,Cardoso V,Fraga J,Carvalho J,Dias LM

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:This study was designed to determine whether a transjugular intrahepatic portosystemic shunt (TIPS) combined with embolotherapy was superior to TIPS alone. METHODS:Seventy-nine patients were included in the study (43 in the TIPS and embolotherapy group and 36 in the TIPS alone group). Embolotherapy was perfo...

journal_title：Journal of clinical gastroenterology

authors： Xiao T,Chen L,Chen W,Xu B,Long Q,Li R,Li L,Peng Z,Fang D,Wang R

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND AIM:Accumulating clinical and epidemiologic evidence indicates that nonalcoholic fatty liver disease (NAFLD) is not only associated with liver-related morbidity and mortality, but also with a greater risk of coronary heart disease (CHD). However, there is currently no diagnostic parameter for NAFLD that ...

journal_title：Journal of clinical gastroenterology

authors： Song Y,Dang Y,Wang P,Tian G,Ruan L

更新日期：2020-03-01 00:00:00

abstract：:Chronic atrophic gastritis (CAG) is closely correlated with gastric cancer and is predominant in Japan. Epidemiologically, food habits are the primary factor in both CAG and gastric cancer. Two potential serum markers for CAG have recently been investigated, i.e., the concentration of serum pepsinogen (PG) and the pre...

journal_title：Journal of clinical gastroenterology

authors： Matsukura N,Onda M,Tokunaga A,Fujita I,Okuda T,Mizutani T,Kyono S,Yamashita K

更新日期：1993-01-01 00:00:00

abstract：:Sixty-four black patients with inflammatory bowel disease (IBD) were seen from 1960 to 1987 at the Medical College of Georgia, representing 22% of all patients with IBD: 38 of them had Crohn's disease (CD) and 26 had ulcerative colitis (UC). In those with CD, the small intestine alone was involved in 16% and ileocolit...

journal_title：Journal of clinical gastroenterology

authors： Simsek H,Schuman BM

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Risk factors for osteoporotic fracture as well as inpatient utilization and mortality have not been thoroughly studied in patients with cirrhosis. We analyzed data from a national database to determine fracture risk in patients with cirrhosis, specific risk factors, and the effect of fractures on he...

journal_title：Journal of clinical gastroenterology

authors： Patel A,Silverman S,Baghdadi J,Shah O,Sundaram V

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:JC virus (JCV) is thought to infect approximately 80% of the human population. Antibodies against JCV can be found in the sera of many people with and without colorectal carcinoma (CRC). We hypothesized that JCV antibody titer will be higher in CRC patients than in healthy controls. AIM:To evaluate this hypo...

journal_title：Journal of clinical gastroenterology

authors： Niv Y,Vilkin A,Levi Z

更新日期：2010-08-01 00:00:00

abstract：:Silybum marianum (milk thistle) and its derivatives have been used for centuries for the treatment of liver disease. This review focuses exclusively on published literature pertaining to the potential use of Silybum marianum or its derivatives for the treatment of alcoholic liver disease. Clinical studies have varied ...

journal_title：Journal of clinical gastroenterology

authors： Ball KR,Kowdley KV

更新日期：2005-07-01 00:00:00

abstract：:Helicobacter pylori infection may play a role in the development of gastric cancer; however, a quantitative evaluation of the density of H. pylori infection has not been reported previously in relation to the histologic stage and type of cancer. This study was designed to compare the density of H. pylori infection to ...

journal_title：Journal of clinical gastroenterology

authors： Tokunaga Y,Shirahase H,Hoppou T,Kitaoka A,Tokuka A,Ohsumi K

更新日期：2000-10-01 00:00:00

abstract：:One hundred forty-six consecutive specimens of excised bowel from patients with Crohn's disease were studied to determine the relationships between strictures, sinuses, and "fissures." A significant coincidence of sinuses and strictures was observed and sinuses tended to arise proximal to the point of maximal strictur...

journal_title：Journal of clinical gastroenterology

authors： Kelly JK,Siu TO

更新日期：1986-10-01 00:00:00

abstract：:In view of therapeutic advances, we carried out meta-analysis of results from 18 randomized, controlled clinical studies to update a previous meta-analysis and to provide an overview of clinical trials involving treatment of functional dyspepsia. The studies were included only if they satisfied inclusion and exclusion...

journal_title：Journal of clinical gastroenterology

authors： Finney JS,Kinnersley N,Hughes M,O'Bryan-Tear CG,Lothian J

更新日期：1998-06-01 00:00:00

abstract：GOALS:The goal of this study was to elucidate the most important predictors for elevation of gastrin in patients on long-term PPI therapy through analysis of data from 2 published studies in Icelandic patients with erosive GERD. BACKGROUND:Gastrin elevation is a known but variable consequence of proton pump inhibitor ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Lund SH,Gizurarson S,Metz DC,Björnsson ES

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:MUC1-glycoprotein is expressed at low levels and in fully glycosylated form on epithelial cells. Inflammation causes MUC1 overexpression and hypoglycosylation. We hypothesized that overexpression of hypoglycosylated MUC1 would be found in postoperative Crohn's disease (CD) recurrence and could be considered ...

journal_title：Journal of clinical gastroenterology

authors： Hashash JG,Beatty PL,Critelli K,Hartman DJ,Regueiro M,Tamim H,Regueiro MD,Binion DG,Finn OJ

更新日期：2021-02-01 00:00:00

abstract：AIM/BACKGROUND:Achalasia may be associated with extraesophageal dysmotility. However, this relation is still poorly understood. In the present study, we used noninvasive real-time ultrasonography to examine the motility function of the gallbladder in the patients with achalasia. MATERIALS AND METHODS:Thirty-three acha...

journal_title：Journal of clinical gastroenterology

authors： Alagozlu H,Unal S,Karakan T,Cindoruk M,Ergun M

更新日期：2008-02-01 00:00:00

abstract：:A large number of ascitic fluid tests, e.g., fibronectin and cholesterol, have been proposed as helpful in detecting malignancy as the cause of ascites. Unfortunately, these "humoral tests of malignancy" are nonspecific. Although the ascitic fluid concentrations of these proteins or protein-bound substances tend to be...

journal_title：Journal of clinical gastroenterology

authors： Runyon BA

更新日期：1994-03-01 00:00:00

abstract：:In healthy volunteers, we studied the effect in intragastric administration of 100 ml 40% alcohol or isotonic saline on the ultrastructure of gastric oxyntic mucosa with emphasis on gastric mucosal microvasculature. We found that a single dose of 40% alcohol produces exfoliation of the surface epithelium, damage to th...

journal_title：Journal of clinical gastroenterology

authors： Tarnawski A,Stachura J,Gergely H,Hollander D

更新日期：1988-01-01 00:00:00

abstract：:Cross-sectional imaging is frequently used in the diagnosis of pancreatic cysts, but there can be overlap in radiographic appearance. We present a case of a patient with presumed intraductal papillary mucinous neoplasm (IPMN) who was ultimately found to have a serous cystadenoma in communication with the pancreatic du...

journal_title：Journal of clinical gastroenterology

authors： Berman L,Mitchell KA,Israel G,Salem RR

更新日期：2010-07-01 00:00:00

abstract：:The authors report a rare case of hepatocellular carcinoma (HCC) that developed 6 years after a sustained and complete response to interferon (IFN) therapy for chronic hepatitis C. A 61-year-old Japanese man presented with a mass in the liver that was diagnosed as HCC. Six years earlier he was treated with IFN-alpha a...

journal_title：Journal of clinical gastroenterology

authors： Yamaguchi K,Omagari K,Kinoshita H,Yoshioka S,Furusu H,Takeshima F,Nanashima A,Yamaguchi H,Kohno S

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Leaky gut, or intestinal permeability, is the phenomenon of the gut wall exhibiting increased absorbency. It is pretty well recognised that an altered or damaged bowel lining or gut wall may result from unbalanced diet, parasites, infection, or medications and that this allows substances such as toxins, micr...

journal_title：Journal of clinical gastroenterology

authors： Del Piano M,Balzarini M,Carmagnola S,Pagliarulo M,Tari R,Nicola S,Deidda F,Pane M

更新日期：2014-11-01 00:00:00

abstract：:Chylous ascites remains rare as a complication of surgical intervention. Although therapeutic manoeuvres to control chylous ascites have been developed over the past 20 years, its pathophysiology is poorly understood. Conservative approaches involving dietary restriction of long-chain triglycerides and salt, together ...

journal_title：Journal of clinical gastroenterology

authors： Ohri SK,Patel T,Desa LA,Spencer J

更新日期：1990-12-01 00:00:00

abstract：GOAL:To provide the statistical predictive model for neoplastic potential of gallbladder polyp (GBP). BACKGROUND:Many studies have attempted to define the risk factors for neoplastic potential of GBP. It remains difficult to precisely adapt the reported risk factors for the decision of surgery. Estimating the probabil...

journal_title：Journal of clinical gastroenterology

authors： Yang JI,Lee JK,Ahn DG,Park JK,Lee KH,Lee KT,Chi SA,Jung SH

更新日期：2018-03-01 00:00:00

abstract：:The synthesis of prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in colonic mucosal cells was investigated in 7 patients and 10 controls. Biopsies obtained from the descending colon were isolated biochemically by a special technique and the suspension of isolated colonic cells was incubated during 45 min. Compared w...

journal_title：Journal of clinical gastroenterology

authors： Baumeister B,Schmidt C,Helisch A,Kipnowski J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:There was some ambiguity in the recent guidelines on the use of capsule endoscopy (CE) in cases of iron deficiency anemia (IDA). GOAL:We aimed to examine the yield of CE in diagnosing the cause of IDA and to define clinical parameters that predict higher diagnostic yields. MATERIALS AND METHODS:A total of ...

journal_title：Journal of clinical gastroenterology

authors： Stone J,Grover K,Bernstein CN

更新日期：2020-05-01 00:00:00

abstract：:We report the development of ulcerative colitis (UC) and Crohn's disease (CD) Health Status Scales that improve on existing inflammatory bowel disease (IBD) activity measures by their added association with health status. We surveyed 991 members of the Crohn's and Colitis Foundation of America (CCFA) and analyzed the ...

journal_title：Journal of clinical gastroenterology

authors： Drossman DA,Li Z,Leserman J,Patrick DL

更新日期：1992-09-01 00:00:00

abstract：:We have studied the morphologic aspects of the duodenal bulb in relation to Helicobacter pylori infection in a large group of patients with endoscopically assessed duodenitis to learn more about the pathogenesis of nonspecific duodenitis (bulbitis) and to clarify the specific role of H. pylori. Eight duodenal biopsy s...

journal_title：Journal of clinical gastroenterology

authors： Caselli M,Gaudio M,Chiamenti CM,Trevisani L,Sartori S,Saragoni L,Boldrini P,Dentale A,Ruina M,Alvisi V

更新日期：1998-01-01 00:00:00

abstract：:Crohn's disease is believed to have an immunologic basis. The importance of the CD4 cell in particular has been supported by several reports of patients whose symptoms of Crohn's disease resolved after a decline in CD4 count associated with human immunodeficiency virus (HIV) infection. A patient with known Crohn's dis...

journal_title：Journal of clinical gastroenterology

authors： Lautenbach E,Lichtenstein GR

更新日期：1997-09-01 00:00:00