Small-volume gallbladders and decreased motility in patients with achalasia.

Abstract:

AIM/BACKGROUND:Achalasia may be associated with extraesophageal dysmotility. However, this relation is still poorly understood. In the present study, we used noninvasive real-time ultrasonography to examine the motility function of the gallbladder in the patients with achalasia. MATERIALS AND METHODS:Thirty-three achalasic patients and 33 healthy volunteers were included in the study. All subjects were investigated after 12 hours of fasting and 30 minutes after a standard test meal. Premeal and postmeal gallbladder volumes were used for calculation of the ejection fraction of the gallbladder and fasting gallbladder volume. RESULTS:The mean fasting volume (18.52+/-1.45 vs. 24.63+/-1.84 cm; P<0.05) and ejection fractions of gallbladder (35.84+/-4.12 vs. 54.47+/-2.47; P<0.05) in the patients with achalasia were lower than the control group. CONCLUSIONS:Such a finding may confirm the possible extraesophageal extension of primary achalasia. Achalasic patients have smaller gallbladders than do others. It could be speculated that it is congenital and/or achalasic patients' gallbladder has incomplete relaxation (as in the lower esophageal sphincter of the achalasia).

journal_name

J Clin Gastroenterol

authors

Alagozlu H,Unal S,Karakan T,Cindoruk M,Ergun M

doi

10.1097/01.mcg.0000225682.52712.f7

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

191-3

issue

2

eissn

0192-0790

issn

1539-2031

pii

00004836-200802000-00014

journal_volume

42

pub_type

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