Cardiomyopathy unrecognized as a cause of hepatic failure.

abstract：:Sjogren syndrome (SS) is an autoimmune disease that affects exocrine glands and therefore may affect the gastrointestinal system, from the mouth, esophagus, and bowel to the liver and pancreas. Oral involvement in SS is mainly characterized by dryness, with a wide spectrum of symptoms, from mild-to-severe xerostomia w...

journal_title：Journal of clinical gastroenterology

authors： Ebert EC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Autoimmune hepatitis (AIH) is an immune mediated chronic liver disease with a prevalence of 17 cases/100,000. Resistance to the standard treatment of AIH (prednisone and azathioprine) occurs in 15% to 20%. There is currently no standard treatment of patients with steroid refractory AIH. GOALS:Determine the ...

journal_title：Journal of clinical gastroenterology

authors： Aqel BA,Machicao V,Rosser B,Satyanarayana R,Harnois DM,Dickson RC

更新日期：2004-10-01 00:00:00

abstract：:Zoonotic visceral leishmaniasis is common in western Mediterranean countries. A strong link between visceral leishmaniasis and human immunodeficiency virus (coinfection) has been proved, especially in Spain, which is an endemic area. This suggests that Leishmania may behave opportunistically. We report a case of colon...

journal_title：Journal of clinical gastroenterology

authors： Sebastián JJ,García S,Soria MT,Pac J,Vicente J,Uribarrena R

更新日期：1997-12-01 00:00:00

abstract：:The goal of every routine endoscopy in the gut is the early diagnosis of malignant and premalignant changes of the mucosa. Chromo- and magnifying endoscopes are exciting new tools and offer detailed analysis of the colonic mucosal surface and pit pattern architecture. This review summarizes recent advances in endoscop...

journal_title：Journal of clinical gastroenterology

authors： Kiesslich R,Jung M,DiSario JA,Galle PR,Neurath MF

更新日期：2004-01-01 00:00:00

abstract：:The bewildering array of medications in the therapy of inflammatory bowel disease (IBD) often confounds the clinician in the choice of specific agents regarding the balance between safety and efficacy. This review surveys and evaluates currently available IBD therapies as well as those used in clinical trials of ulcer...

journal_title：Journal of clinical gastroenterology

authors： Katz S

更新日期：2002-04-01 00:00:00

abstract：:Hirschsprung's disease is one of the more common causes of childhood bowel obstruction. The disease can cause enterocolitis which, untreated, may result in considerable mortality. We describe our evaluation of two infants who suffered from intractable diarrhea of infancy secondary to Hirschsprung's disease. We found t...

journal_title：Journal of clinical gastroenterology

authors： Branski D,Lebenthal E

更新日期：1979-09-01 00:00:00

abstract：:The direct effects of exogenous and endogenous prostaglandins (PGs) on damage to isolated gastric cells caused by ethanol were assessed in rats. 16,16-Dimethyl-PGE2 (dmPGE2) significantly inhibited cellular damage caused by 15% ethanol in three fractions rich in surface epithelial cells, rich in parietal cells, and ri...

journal_title：Journal of clinical gastroenterology

authors： Arakawa T,Nakamura A,Fukuda T,Satoh H,Kobayashi K

更新日期：1988-01-01 00:00:00

abstract：:Few alternative treatments are available for those patients with autoimmune chronic active hepatitis who fail to respond to the conventional treatment of corticosteroids. Such patients have a poor prognosis and frequently require liver transplantation. We report a patient with autoimmune hepatitis who failed treatment...

journal_title：Journal of clinical gastroenterology

authors： Person JL,McHutchison JG,Fong TL,Redeker AG

更新日期：1993-12-01 00:00:00

abstract：:Patients who are hepatitis B surface antigen (HBsAg) positive are at risk for hepatitis flare when receiving cytotoxic or immunosuppressive therapy. It has been reported that as high as 50% of HBsAg-positive individuals who undergo chemotherapy develop elevation of liver transaminases. According to current Association...

journal_title：Journal of clinical gastroenterology

authors： Wu JM,Huang YH,Lee PC,Lin HC,Lee SD

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND & AIMS:Cyclic vomiting syndrome (CVS) is characterized by episodes of nausea and vomiting separated by symptom-free intervals. Rome IV guidelines have now distinguished CVS from other disorders such as cannabinoid hyperemesis. The pathogenesis of CVS, however, is poorly understood. Limited data exist on gast...

journal_title：Journal of clinical gastroenterology

authors： Kamal A,Sarvepalli S,Selvakumar P,Lopez R,Radhakrishnan K,Gabbard S

更新日期：2020-10-01 00:00:00

abstract：:Repeated surgical interventions on the biliary ductal system increase morbidity and mortality, particularly in the geriatric patient. In an attempt to prevent these complications, side-to-side choledochoduodenostomy was performed as the primary operative procedure in 54 patients, age 72 +/- 13 years. This was the pati...

journal_title：Journal of clinical gastroenterology

authors： Berlatzky Y,Freund HR

更新日期：1990-08-01 00:00:00

abstract：:Ranitidine and cimetidine are competitive antagonists of histamine at H2-receptor sites in the gastric mucosa. Both drugs reduce output of basal and stimulated gastric acid and pepsin secretion in normal healthy subjects and duodenal ulcer patients. Pharmacodynamic and pharmacokinetic differences exist between the dru...

journal_title：Journal of clinical gastroenterology

authors： Richards DA

更新日期：1983-01-01 00:00:00

abstract：:Aminosalicylates are of proven benefit in maintaining medically induced remissions of both ulcerative colitis and Crohn's disease. Even rectal 5-aminosalicylic acid has been found to be useful in maintaining long-term remissions of distal ulcerative colitis. Particularly noteworthy is the demonstrated efficacy of oral...

journal_title：Journal of clinical gastroenterology

authors： Sachar DB

更新日期：1995-03-01 00:00:00

abstract：:Patients affected by uncomplicated diverticular disease (DD) suffer from colicky, unexplained, recurrent, and short-lived but often debilitating abdominal pain and alteration in bowel habit. Although the goals of therapy, such as to improve symptoms and to prevent both recurrent attacks and complications, are clearly ...

journal_title：Journal of clinical gastroenterology

authors： Rocco A,Compare D,Caruso F,Nardone G

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The clinical effect of probiotics on irritable bowel syndrome (IBS) is still controversial. AIMS:We aimed to evaluate the effects of a probiotic mixture on IBS symptoms and the composition of fecal microbiota in patients with diarrhea-dominant IBS (D-IBS). METHODS:Fifty patients with D-IBS were randomized ...

journal_title：Journal of clinical gastroenterology

authors： Ki Cha B,Mun Jung S,Hwan Choi C,Song ID,Woong Lee H,Joon Kim H,Hyuk J,Kyung Chang S,Kim K,Chung WS,Seo JG

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Although of unproven benefit for nonalcoholic steatohepatitis (NASH), thiazolidinediones (TZDs) have emerged as a promising therapy. Little evidence exists, however, regarding sustained effects of TZDs in NASH after drug discontinuation. A recent clinical study suggests that relapse of NASH pathophysiology i...

journal_title：Journal of clinical gastroenterology

authors： Argo CK,Iezzoni JC,Al-Osaimi AM,Caldwell SH

更新日期：2009-07-01 00:00:00

abstract：:The human large intestine harbors a complex microbiota containing many hundreds of different bacterial species. Although structure/function relationships between different components of the microbiota are unclear, this complex multicellular entity plays an important role in maintaining homeostasis in the body. Many of...

journal_title：Journal of clinical gastroenterology

authors： Macfarlane GT,Macfarlane S

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The prevalence of duodenal ulcer (DU) has been considered high in patients with chronic pancreatitis; however, its pathogenesis is unclear. We hypothesized that Helicobacter pylori infection plays the major pathogenetic role. STUDY:One hundred seven cases (97 men, 10 women) of chronic alcoholic pancreatitis...

journal_title：Journal of clinical gastroenterology

authors： Chebli JM,de Souza AF,Gaburri PD,Bastos KV,Ribeiro TC,Filho RJ,Chebli LA,Castro Ferreira LE

更新日期：2002-07-01 00:00:00

abstract：:Despite the successful FDA approval of sorafenib as the standard of care therapy in patients with advanced hepatocellular carcinoma (HCC), its clinical benefits have been modest. The mortality rate remains high and prognosis poor for patients with advanced-stage HCC. The exact mechanism of sorafenib in the treatment o...

journal_title：Journal of clinical gastroenterology

authors： Lee JK,Abou-Alfa GK

更新日期：2013-07-01 00:00:00

abstract：AIM:To define whether human colonic mucosa exposure to Lactobacillus rhamnosus GG (LGG), American Type Culture Collection (ATCC) 53103, may influence intestinal muscle cell contractility. METHODS:Human colon specimens were obtained from disease-free margins of resected segments for cancer. The mucosa and submucosa, af...

journal_title：Journal of clinical gastroenterology

authors： Guarino MP,Altomare A,Stasi E,Marignani M,Severi C,Alloni R,Dicuonzo G,Morelli L,Coppola R,Cicala M

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Abnormal pancreatic function tests have been reported to precede the imaging findings of chronic pancreatitis. Magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP) is increasingly accepted as the primary imaging modality for the detection of structural changes of early mild...

journal_title：Journal of clinical gastroenterology

authors： Alkaade S,Cem Balci N,Momtahen AJ,Burton F

更新日期：2008-09-01 00:00:00

abstract：:6-mercaptopurine (6-MP) and azathioprine (AZA) are used to treat inflammatory bowel disease (IBD). Side effects include infection, leukopenia, hepatitis, and pancreatitis. The level of thiopurine methyltransferase (TPMT), which metabolizes 6-MP to 6-methylmercaptopurine, may reflect the risk of side effects. We sought...

journal_title：Journal of clinical gastroenterology

authors： Kader HA,Wenner WJ Jr,Telega GW,Maller ES,Baldassano RN

更新日期：2000-06-01 00:00:00

abstract：:We identified spontaneous reactivation of hepatitis B virus (HBV) retrospectively by utilizing serum alanine aminotransferase and HBV DNA in 19 men (79% homosexual), with an estimated annual incidence of 7.3%. In 11 patients, spontaneous reactivation occurred as a single episode and in eight patients, reactivation was...

journal_title：Journal of clinical gastroenterology

authors： Gupta S,Govindarajan S,Fong TL,Redeker AG

更新日期：1990-10-01 00:00:00

abstract：GOALS:To describe the association of untreated celiac disease with hyperhomocysteinemia and variants of the methylenetetrahydrofolicacid reductase (MTHFR) gene found in clinical practice. STUDY:Case studies with description of associated clinical, biochemical, and genetic findings and review of literature. RESULTS:Fi...

journal_title：Journal of clinical gastroenterology

authors： Wilcox GM,Mattia AR

更新日期：2006-08-01 00:00:00

abstract：:At least five hepatitis viruses are known to date. Infection by enterically transmitted viruses (HAV and HEV) is generally benign compared with the disease caused by parenterally transmitted viruses (HBV, HCV, and HDV). Chronic infection by HBV is common and may evolve to cirrhosis and hepatocellular carcinoma (HCC). ...

journal_title：Journal of clinical gastroenterology

authors： Pujol FH,Devesa M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Nocturnal gastroesophageal reflux disease (GERD) has been associated with severe complications including erosive esophagitis, peptic stricture, and even esophageal adenocarcinoma and is known to cause a decreased health-related quality of life. However, there is limited information on independent predictors ...

journal_title：Journal of clinical gastroenterology

authors： Gaddam S,Maddur H,Wani S,Gupta N,Singh M,Singh V,Moloney B,Puli SR,Rastogi A,Bansal A,Sharma P

更新日期：2011-10-01 00:00:00

abstract：GOALS:To evaluate the incidence of extraesophageal malignancies among patients with Barrett esophagus (BE). BACKGROUND:Gastroesophageal reflux disease has been reported to be associated with upper aerodigestive malignancies. BE is considered a consequence of long-standing gastroesophageal reflux disease; however, the ...

journal_title：Journal of clinical gastroenterology

authors： Pines G,Dickman R,Niv Y,Kashtan H,Birkenfeld S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:The role of alcohol consumption in insulin resistance remains unclear. The aim of this study was to examine the association between alcohol consumption and insulin resistance in a large asymptomatic population. METHODS:A total of 2463 asymptomatic Japanese men aged 28 years or above undergoing a com...

journal_title：Journal of clinical gastroenterology

authors： Gunji T,Matsuhashi N,Sato H,Iijima K,Fujibayashi K,Okumura M,Sasabe N,Urabe A

更新日期：2011-10-01 00:00:00

abstract：:Physicians sometimes forget nongastrointestinal causes of abdominal pain. Yet, abdominal pain was the major complaint of three patients with ureteropelvic junction obstruction (UPJ). Definitive diagnosis can be made either by a "hydration" intravenous pyelogram or by an intravenous pyelogram during an attack. ...

journal_title：Journal of clinical gastroenterology

authors： Butler ML

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Twenty-four-hour multichannel intraluminal impedance and pH (MII-pH) esophageal monitoring allows detection of both acid and nonacid gastroesophageal reflux episodes. The MII-pH catheter contains 6 impedance segments placed 3, 5, 7, 9, 15, and 17 cm above the lower esophageal sphincter (LES), plus a pH elect...

journal_title：Journal of clinical gastroenterology

authors： Hila A,Chowdhury N,Hajar N,Castell DO

更新日期：2011-11-01 00:00:00