Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease.

abstract：GOALS:To investigate the association between treatment nonadherence and patients' knowledge of the prescribed medication among individuals with inflammatory bowel disease (IBD), and evaluate the impact of nonadherence on relapse. BACKGROUND:The patient's knowledge of the prescribed medication has been identified as an...

journal_title：Journal of clinical gastroenterology

authors： Tae CH,Jung SA,Moon HS,Seo JA,Song HK,Moon CM,Kim SE,Shim KN,Jung HK

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Endoscopic follow-up (FU) in patients treated for colorectal adenomas or cancer (CRC) is intended to reduce the incidence of CRC. In the Dutch postpolypectomy guidelines, the FU interval is solely determined by the number of previous adenomas, whereas in other countries size and histology are also taken into...

journal_title：Journal of clinical gastroenterology

authors： Mulder SA,Ouwendijk RJ,van Leerdam ME,Nagengast FM,Kuipers EJ

更新日期：2008-05-01 00:00:00

abstract：GOALS:We evaluated the efficacy of initial and follow-up hepatic venous pressure gradient (HVPG), models of end-stage liver disease (MELD), and MELD-Na for predicting the survival of patients with decompensated liver cirrhosis (LC). BACKGROUND:MELD with/without Na score and HVPG have been important predictors of morta...

journal_title：Journal of clinical gastroenterology

authors： Suk KT,Kim CH,Park SH,Sung HT,Choi JY,Han KH,Hong SH,Kim DY,Yoon JH,Kim YS,Baik GH,Kim JB,Kim DJ

更新日期：2012-11-01 00:00:00

abstract：:Forty-five patients with systemic lupus erythematosus (SLE) underwent a cross-sectional study to evaluate intestinal secretory immunity. Peroral jejunal biopsy with histologic and immunohistochemical assessment of the mucosa were carried out in the patients and in 12 healthy volunteers. It was observed that an altered...

journal_title：Journal of clinical gastroenterology

authors： Elia C,Souza H,Carvalho AT,Madi K,Mello CA,Oliveira A,Cuckier R,Papi JA

更新日期：2000-01-01 00:00:00

abstract：:In a double-blind placebo-controlled study, we examined the effect of calcitonin on gastric emptying, and on serum concentrations of gastrin, insulin, glucose, calcium, and phosphorus after a mixed solid-liquid meal in 11 healthy men. Synthetic salmon calcitonin was administered as a 415 pmol i.v. bolus injection foll...

journal_title：Journal of clinical gastroenterology

authors： Jonderko K,Jonderko G,Gołab T

更新日期：1990-02-01 00:00:00

abstract：:Sjogren syndrome (SS) is an autoimmune disease that affects exocrine glands and therefore may affect the gastrointestinal system, from the mouth, esophagus, and bowel to the liver and pancreas. Oral involvement in SS is mainly characterized by dryness, with a wide spectrum of symptoms, from mild-to-severe xerostomia w...

journal_title：Journal of clinical gastroenterology

authors： Ebert EC

更新日期：2012-01-01 00:00:00

abstract：:A 24-year-old man with addisonian pernicious anemia, adult celiac disease and selective IgA deficiency is presented to emphasize the differential diagnosis of vitamin B12 deficient megaloblastic anemia in association with small intestinal mucosal abnormalities and the relationships between immunoglobulin deficiency, p...

journal_title：Journal of clinical gastroenterology

authors： Quigley EM,Carmichael HA,Watkinson G

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Quantitative information is scarce with regard to guidelines for currently prescribed medications for constipation. Furthermore, these guidelines do not reflect the differences in the number of bowel movements caused by each drug. GOALS:In this study, we used a model-based meta-analysis to quantitatively es...

journal_title：Journal of clinical gastroenterology

authors： Zhang Y,Yin F,Xu L,Li YF,Chen JC,Liu HX,Zheng QS,Li LJ

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The efficacy of 6-mercaptopurine (6-MP) in the treatment and long-term maintenance of remission of inflammatory bowel disease and prevention of recurrence after resection in Crohn's disease have been established. Concern about 6-MP toxicity remains, especially the development of neoplasm. The aim of...

journal_title：Journal of clinical gastroenterology

authors： Warman JI,Korelitz BI,Fleisher MR,Janardhanam R

更新日期：2003-09-01 00:00:00

abstract：:Gastrointestinal (GI) disturbances are common during training and competition, especially among endurance athletes. Historically, little attention has been paid to the psychobiological etiology of GI problems in sport. The aim of this review is to: (1) provide a physiological overview of how psychological stress and a...

journal_title：Journal of clinical gastroenterology

authors： Wilson PB

更新日期：2020-04-01 00:00:00

abstract：:Lactobacillus species are part of normal gastrointestinal flora and are an uncommon cause of bacteremia. Lactobacillus casei subsp. rhamnosus was repeatedly isolated in the blood cultures of a 43-year-old woman with ulcerative colitis. Lactobacillus spp. could be considered a potential opportunistic pathogen whenever ...

journal_title：Journal of clinical gastroenterology

authors： Farina C,Arosio M,Mangia M,Moioli F

更新日期：2001-09-01 00:00:00

abstract：:We observed jejunal water and sodium secretion in two patients with chronic idiopathic intestinal pseudo-obstruction by standard perfusion techniques. The ability of glucose to reverse this secretory state was impaired. These observations suggest that a jejunal secretory state may contribute to the diarrhea in chronic...

journal_title：Journal of clinical gastroenterology

authors： Rolston DD,Hunt JB,Fairclough PD,Wilks M,Levison DA,Clark ML,Farthing MJ

更新日期：1990-04-01 00:00:00

abstract：:The prevalence of hepatitis C virus (HCV)-RNA positivity among hemodialysis patients varies between 10 and 70%. Few previous surveys revealed high frequency of seroconversion of HCV-RNA-negative patients over the years of hemodialysis. Only few studies reported HCV genotype variability. We evaluated all 65 patients on...

journal_title：Journal of clinical gastroenterology

authors： Zamir D,Storch S,Zonder HB,Zamir C,Weiner P

更新日期：1999-01-01 00:00:00

abstract：:We recently treated a patient with adult-onset Still's disease who developed macrophage activation syndrome (MAS) secondary to disseminated histoplasmosis while being treated with adalimumab. The gastroenterology service was consulted early, before diagnosis, as the patient presented with elevated liver enzymes and di...

journal_title：Journal of clinical gastroenterology

authors： Jayakar BA,Hashkes PJ

更新日期：2011-03-01 00:00:00

abstract：:A prospective clinical, endoscopic, and histopathologic study of the esophagus was carried out in 24 patients with advanced liver disease who underwent esophageal variceal sclerotherapy (EVS) and who eventually came to autopsy. Patients were arbitrarily divided into three groups: acute (group I), intermediate (group I...

journal_title：Journal of clinical gastroenterology

authors： Kage M,Korula J,Harada A,Mucientes F,Kanel G,Peters RL

更新日期：1987-12-01 00:00:00

abstract：:A 35-year-old man developed leg edema, marked hypoalbuminemia, and proteinuria. Subsequent renal biopsy revealed a diffuse membranoproliferative glomerulonephritis and, on electron microscopy, typical electron-dense deposits characteristic of an immune complex pathogenesis. Although protein wasting might have readily ...

journal_title：Journal of clinical gastroenterology

authors： Scholey J,Freeman HJ

更新日期：1986-04-01 00:00:00

abstract：:Two patients with primary malignant lymphoma underwent spontaneous regression. One was a 40-year-old woman with a large ulcerating tumor on the greater curvature of the gastric antrum. This tumor shrank spontaneously, leaving only a small shallow ulcer. The resected specimen showed a minute focus of malignant lymphoma...

journal_title：Journal of clinical gastroenterology

authors： Shigematsu A,Iida M,Lien GS,Imamura T,Okada M,Fuchigami T,Fujishima M,Itoh H,Iwashita A

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:An association between Helicobacter pylori infection and colorectal neoplasia has been reported in cross-sectional studies. GOALS:We examined the association between H. pylori infection and the development of advanced colorectal neoplasia (AN) in a screening cohort. STUDY:We identified 3753 adults, who und...

journal_title：Journal of clinical gastroenterology

authors： Ryoo SK,Kim TJ,Kim ER,Hong SN,Kim YH,Chang DK

更新日期：2020-09-01 00:00:00

abstract：:A randomized, multicenter, double-blind, placebo-controlled study was conducted to determine whether ranitidine 150 mg b.i.d. for 6 weeks would expedite endoscopic healing or relief of symptoms in patients with benign gastric ulcer. Of 203 patients enrolled, 101 received ranitidine and 102 received placebo. Endoscopic...

journal_title：Journal of clinical gastroenterology

authors： Hirschowitz BI,DeLuca V,Graham D,Lorber S,Bright-Asare P,Katon R

更新日期：1986-06-01 00:00:00

abstract：:A fifty-year-old woman with abdominal pain, diarrhea, and weight loss ultimately required exploratory laparotomy. The entire small intestine was extensively infiltrated by poorly differentiated adenocarcinoma; mesenteric lymph nodes and surrounding omentum were involved, but no extragastrointestinal tumor was found. A...

journal_title：Journal of clinical gastroenterology

authors： Hansen RM,Lewis JD,Janjan NA,Komorowski RA

更新日期：1988-04-01 00:00:00

abstract：:In this paper, I have focused on the issue of the clinical gastroenterologist who refuses to evaluate and endoscope the patient with AIDS. The discussion centers around the legal and ethical properties of such a decision, and the legal doctrine of abandonment. Finally, I have reviewed recent recommendations regarding ...

journal_title：Journal of clinical gastroenterology

authors： Plumeri PA

更新日期：1984-06-01 00:00:00

abstract：GOAL:The goal of this study is to determine factors associated with performance of duodenal biopsy during upper endoscopy. BACKGROUND:Celiac disease (CD) prevalence approaches 1% in the United States and Europe, yet CD remains underdiagnosed, in part because of low rates of duodenal biopsy during upper endoscopy. We a...

journal_title：Journal of clinical gastroenterology

authors： Pitman M,Sanders DS,Green PHR,Lebwohl B

更新日期：2019-02-01 00:00:00

abstract：AIM:To investigate the effects of prolonged tricyclic antidepressants (TCAs) therapy on the frequency and duration of episodes of cyclic vomiting syndrome (CVS) in adults, and the global assessment of clinical improvement and the number of emergency department (ED) visits and/or hospitalizations. METHOD:An open labele...

journal_title：Journal of clinical gastroenterology

authors： Hejazi RA,Reddymasu SC,Namin F,Lavenbarg T,Foran P,McCallum RW

更新日期：2010-01-01 00:00:00

abstract：:Steatocrit is a semiquantitative method for determination of fat content in fecal samples. Previous studies, mostly performed in children, reported controversial results. The aim of our study was to compare the determination of fat content in 148 fecal samples by two methods: the conventional van de Kamer and the stea...

journal_title：Journal of clinical gastroenterology

authors： Sugai E,Srur G,Vazquez H,Benito F,Mauriño E,Boerr LA,Bai JC

更新日期：1994-10-01 00:00:00

abstract：:Dietary intake and plasma lipids were estimated in 200 patients with gallstones and 98 control subjects from a hospital in Northern India and were matched for age, sex, and social class. The intake of total calories and carbohydrates and the plasma triglyceride values were higher in all gallstone patients as compared ...

journal_title：Journal of clinical gastroenterology

authors： Tandon RK,Saraya A,Paul S,Kapur BM

更新日期：1996-01-01 00:00:00

abstract：GOALS:We aimed to quantify pharyngeal exposure to gastric contents in patients diagnosed with reflux-related hoarseness and healthy controls using new diagnostic techniques. BACKGROUND:Hoarseness with typical signs on laryngoscopy is commonly thought to be caused by esophagopharyngeal reflux. New methods are proposed ...

journal_title：Journal of clinical gastroenterology

authors： Hayat JO,Yazaki E,Moore AT,Hicklin L,Dettmar P,Kang JY,Sifrim D

更新日期：2014-04-01 00:00:00

abstract：:An unusual case of malignant pancreatic composite tumor with both components of acinar cell tumor (ACT) and islet cell tumor (ICT) was investigated histologically, immunohistochemically, and ultrastructurally. The pancreatic tumor with central cyst formation was found on computerized tomographic examination of a 72-ye...

journal_title：Journal of clinical gastroenterology

authors： Muramatsu T,Kijima H,Tsuchida T,Konagaya M,Matsubayashi H,Tada N,Nakamura M,Ueyama Y

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND & AIMS:Cyclic vomiting syndrome (CVS) is characterized by episodes of nausea and vomiting separated by symptom-free intervals. Rome IV guidelines have now distinguished CVS from other disorders such as cannabinoid hyperemesis. The pathogenesis of CVS, however, is poorly understood. Limited data exist on gast...

journal_title：Journal of clinical gastroenterology

authors： Kamal A,Sarvepalli S,Selvakumar P,Lopez R,Radhakrishnan K,Gabbard S

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Visual characteristics seen during digital single-operator cholangioscopy (DSOC) have not been validated. The aim of this 2-phase study was to define terminology by consensus for the visual diagnosis of biliary lesions to develop a model for optimization of the diagnostic performance of DSOC. MATERIALS AND ...

journal_title：Journal of clinical gastroenterology

authors： Sethi A,Tyberg A,Slivka A,Adler DG,Desai AP,Sejpal DV,Pleskow DK,Bertani H,Gan SI,Shah R,Arnelo U,Tarnasky PR,Banerjee S,Itoi T,Moon JH,Kim DC,Gaidhane M,Raijman I,Peterson BT,Gress FG,Kahaleh M

更新日期：2020-02-07 00:00:00

abstract：:It is becoming increasingly recognized that purely clinical endpoints may not be sufficient in the treatment of patients with inflammatory bowel disease. As such, mucosal disease assessment has become a prominent component of the majority of recent clinical trials in Crohn's disease and ulcerative colitis. There is mo...

journal_title：Journal of clinical gastroenterology

authors： Osterman MT

更新日期：2013-03-01 00:00:00