Cumulative experience with short- and long-term toxicity to 6-mercaptopurine in the treatment of Crohn's disease and ulcerative colitis.

abstract：:We report a patient in whom cyproheptadine-induced hepatitis was followed by prolonged cholestasis marked by elevation of serum alkaline phosphatase levels, gammaglutamyltransferase and bile acid levels, and disappearance of small bile ducts. Chlorpromazine and imipramine, which can induce a similar acute hepatitis fo...

journal_title：Journal of clinical gastroenterology

authors： Larrey D,Geneve J,Pessayre D,Machayekhi JP,Degott C,Benhamou JP

更新日期：1987-02-01 00:00:00

abstract：:To determine whether the urease-based CLOtest or low-dose 14C urea breath test can predict severity of gastritis or the presence of peptic ulcers, we studied 84 patients presenting for upper endoscopy. Antral biopsies were obtained for histologic analysis and CLOtesting, and urea breath testing was performed. The time...

journal_title：Journal of clinical gastroenterology

authors： Lewis JD,Kroser J,Bevan J,Furth EE,Metz DC

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Spiral enteroscopy (SE) has emerged as a new alternative for deep intubation of the small intestine. SE is most often used to evaluate abnormal findings on capsule endoscopy (CE). OBJECTIVE:Investigate the ability of SE to reproduce abnormal findings detected on preceding CE. DESIGN:Prospective study. SET...

journal_title：Journal of clinical gastroenterology

authors： Buscaglia JM,Richards R,Wilkinson MN,Judah JR,Lam Y,Nagula S,Draganov PV

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Cirrhosis is a major milestone in patients with chronic liver disease because of its impact on patient morbidity and mortality. Chronic hepatitis B (CHB) and hepatitis C (CHC) are important causes of cirrhosis. This systematic review examines the relevant literature and evidence to assess whether cirrhosis...

journal_title：Journal of clinical gastroenterology

authors： Manne V,Akhtar E,Saab S

更新日期：2014-10-01 00:00:00

abstract：:Ornithine transcarbamylase (OTC) is a mitochondrial-matrix enzyme that catalyzes conversion of ornithine and carbamyl phosphate to citrulline, the second step in the urea cycle. The urea cycle is the most important pathway to detoxification of ammonia in human beings. Ornithine transcarbamylase deficiency (OTCD) is th...

journal_title：Journal of clinical gastroenterology

authors： Trivedi M,Zafar S,Spalding MJ,Jonnalagadda S

更新日期：2001-04-01 00:00:00

abstract：:In 23 patients with dermatitis herpetiformis (DH) and five patients with linear-IgA bullous dermatosis (BD), we evaluated the occurrence of histologic jejunal changes and small-bowel function abnormalities. None of the patients showed clinical signs or symptoms of malabsorption. Morphological jejunal changes consisten...

journal_title：Journal of clinical gastroenterology

authors： deFranchis R,Primignani M,Cipolla M,Vecchi M,Agape D,Monti M,Berti E,Zuccato E,Mussini E

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND AND THE STUDY AIM:Crohn's disease (CD) is a chronic inflammatory disorder defined as a transmural inflammation of the bowel wall, affecting the small and large intestine. The Capsule Endoscopy Crohn's Disease Activity Index (CECDAI or Niv score) was devised to measure mucosal disease activity. We extended th...

journal_title：Journal of clinical gastroenterology

authors： Niv Y,Gal E,Gabovitz V,Hershkovitz M,Lichtenstein L,Avni I

更新日期：2018-01-01 00:00:00

abstract：:In the current COVID-19 pandemic, there has been concern regarding the use of ibuprofen and other nonsteroidal anti-inflammatory agents by COVID-19 infected patients. Aminosalicylates (5-ASAs) are structurally similar and have anti-inflammatory functions that resemble those of nonsteroidal anti-inflammatory agents. Si...

journal_title：Journal of clinical gastroenterology

authors： Ehrenpreis ED,Kruchko DH

更新日期：2020-08-01 00:00:00

abstract：:Pyogenic abscesses of the liver occur in association with a variety of diseases. Sometimes they are caused by anaerobic infections of liver metastases. Uncommonly, however, multiple hepatic abscesses caused by anaerobic bacteria are the presenting signs of unsuspected colonic cancer in the absence of liver metastases....

journal_title：Journal of clinical gastroenterology

authors： Lonardo A,Grisendi A,Pulvirenti M,Della Casa G,Melini L,Di Gregorio C,Nasi G,Sarti M,Tamborrino E,Lonardo F

更新日期：1992-06-01 00:00:00

abstract：:In a Chinese family with hereditary pancreatitis, two members are proven to have chronic pancreatitis. The propositus, a 31-year-old man, had epigastric pain since the age of 18. Multiple calcifications in the region of the pancreas were seen on plain film of the abdomen, ultrasonography, computed tomography, and endo...

journal_title：Journal of clinical gastroenterology

authors： Lin JT,Wang TH,Chen DS

更新日期：1990-02-01 00:00:00

abstract：:The fear of cancer has evoked calls for intensive surveillance programs in Barrett's esophagus. Two evolving issues are fueling this fire: (a) the rising risk of adenocarcinoma of the esophagus over the past 20 years and (b) the coincidental increase in the recognized prevalence of Barrett's esophagus in the general p...

journal_title：Journal of clinical gastroenterology

authors： Richter JE,Falk GW

更新日期：1996-09-01 00:00:00

abstract：:Two cases of multiple lymphomatous polyposis (MLP) are presented, involving different segments of the gastrointestinal tract. Both cases display the characteristic clinical and pathologic features of MLP. In addition, we were able to document, for the first time, the endoscopic ultrasonographic findings in this diseas...

journal_title：Journal of clinical gastroenterology

authors： Viana HL,Henrique RM,Ferreira ES,Correia AM,Silva RA,Dias LM,Viana RL

更新日期：2002-02-01 00:00:00

abstract：:Portal hypertension, a consequence of end-stage liver disease and liver cirrhosis can lead to significant morbidity and mortality for patients through abnormal fluid accumulation as well as the formation of portosystemic shunts and varices. Treatment of the sequelae of portal hypertension can be achieved through endov...

journal_title：Journal of clinical gastroenterology

authors： Shreve L,Lee EW

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Women with irritable bowel syndrome (IBS) frequently report chronic pelvic pain, however, it is still unanswered whether these are truly separate entities. IBS negatively impacts on quality of life, but the impact of IBS on sexual function is not clear. GOALS:We aimed to (1) describe the impact of IBS on se...

journal_title：Journal of clinical gastroenterology

authors： Choung RS,Herrick LM,Locke GR 3rd,Zinsmeister AR,Talley NJ

更新日期：2010-11-01 00:00:00

abstract：GOALS:We aimed to quantify pharyngeal exposure to gastric contents in patients diagnosed with reflux-related hoarseness and healthy controls using new diagnostic techniques. BACKGROUND:Hoarseness with typical signs on laryngoscopy is commonly thought to be caused by esophagopharyngeal reflux. New methods are proposed ...

journal_title：Journal of clinical gastroenterology

authors： Hayat JO,Yazaki E,Moore AT,Hicklin L,Dettmar P,Kang JY,Sifrim D

更新日期：2014-04-01 00:00:00

abstract：:Microbial signals stimulate development and maintenance of the neonatal immune system. The process begins in utero, with limited exposure to microbes in the intrauterine environment, as well as maternal immune signals priming the developing immune system. After birth and initial colonization, the immune system must be...

journal_title：Journal of clinical gastroenterology

authors： Houghteling PD,Walker WA

更新日期：2015-11-01 00:00:00

abstract：:Two cases of Cruveilhier-Baumgarten syndrome not clinically evident and without esophageal varices in patients with liver cirrhosis and portal hypertension are presented. The diagnosis was made by real-time ultrasonography, which showed echographic caput medusae with large afferent umbilical veins and efferent inferio...

journal_title：Journal of clinical gastroenterology

authors： Caturelli E,Sperandeo G,Squillante MM,Mangia A,Gabbrielli L

更新日期：1989-06-01 00:00:00

abstract：:We report a 50-year-old woman with alpha 1 antitrypsin deficiency (PiSZ phenotype) who developed clinical features of malabsorption after vagotomy and pyloroplasty. The intestinal biopsy demonstrated total villous atrophy with hypertrophy of the crypts. After gluten withdrawal, digestive function and the appearance of...

journal_title：Journal of clinical gastroenterology

authors： Pons Romero F,Casafont F,Rodriguez de Lope C,San Miguel G,Artiñano E,Cagigas J

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Beneficial findings concerning probiotics are increasing day by day. However, one of the most important parameter which affects the probiotic activity of a microorganism is its survival during the gastroduodenal transit. Some microencapsulation techniques could be applied to bacterial cells to improve this p...

journal_title：Journal of clinical gastroenterology

authors： Del Piano M,Carmagnola S,Andorno S,Pagliarulo M,Tari R,Mogna L,Strozzi GP,Sforza F,Capurso L

更新日期：2010-09-01 00:00:00

abstract：:In a 6 to 12-week double-blind trial, the effect of cisapride (10 mg q.i.d.) was compared with that of placebo in 63 patients with esophagitis confirmed by endoscopy and/or biopsy. In only one patient (3%) in the cisapride group but in 43% of the placebo patients (p = 0.001), symptoms had not improved after 6 weeks. F...

journal_title：Journal of clinical gastroenterology

authors： Baldi F,Bianchi Porro G,Dobrilla G,Iascone C,Lobello R,Marzio L,Sabbatini F,Tittobello A,Verme G

更新日期：1988-12-01 00:00:00

abstract：GOALS:We compare bowel cleanliness in patients taking same-day versus split-dose 4-L polyethylene glycol laxative for afternoon colonoscopy. Secondary objectives included patient satisfaction, adverse effects and patient tolerability. BACKGROUND:Afternoon colonoscopies have been associated with inadequate bowel prepar...

journal_title：Journal of clinical gastroenterology

authors： Castro FJ,Al-Khairi B,Singh H,Mohameden M,Tandon K,Lopez R

更新日期：2019-11-01 00:00:00

abstract：:Practitioners of endoscopy often experience musculoskeletal pain and injury (most often in the back, neck, shoulders, hands, wrists, and thumbs) that are associated with the minute and repetitive strain that is placed on these areas during endoscopic procedures. This review of the current documentation of endoscopy-re...

journal_title：Journal of clinical gastroenterology

authors： Harvin G

更新日期：2014-08-01 00:00:00

abstract：GOALS:To determine the incidence of renal function deterioration in adult patients with Salmonella infection. BACKGROUND:Renal impairment has been described during severe Salmonella infection and is mainly due to shock, dehydration, or rhabdomyolysis. However, it is unclear whether less severe Salmonella infection als...

journal_title：Journal of clinical gastroenterology

authors： Janssen van Doorn K,Pierard D,Spapen H

更新日期：2006-11-01 00:00:00

abstract：:We examined California Medicaid (Medi-Cal) service use and expenditures for peptic ulcer and other acid-related diseases during the 10-year period fiscal year (FY) 1976-1985. Between FY 1976 and FY 1980, hospitalizations rose irregularly, operations declined by 37%, endoscopies tripled, physician visits fluctuated fro...

journal_title：Journal of clinical gastroenterology

authors： Bloom BS,Fox NA,Jacobs J

更新日期：1989-12-01 00:00:00

abstract：:In healthy volunteers, we studied the effect in intragastric administration of 100 ml 40% alcohol or isotonic saline on the ultrastructure of gastric oxyntic mucosa with emphasis on gastric mucosal microvasculature. We found that a single dose of 40% alcohol produces exfoliation of the surface epithelium, damage to th...

journal_title：Journal of clinical gastroenterology

authors： Tarnawski A,Stachura J,Gergely H,Hollander D

更新日期：1988-01-01 00:00:00

abstract：:Gastric cancer is often diagnosed in middle-aged patients undergoing upper gastrointestinal endoscopy for abdominal complaints or constitutional symptoms, such as dyspepsia, vomiting or anorexia, weight loss, anemia, jaundice, and ascites. Sometimes, all of these symptoms may be absent, and gastric cancer is diagnosed...

journal_title：Journal of clinical gastroenterology

authors： Perri F,Bisceglia M,Giannatempo GM,Andriulli A

更新日期：2001-07-01 00:00:00

abstract：:A case of heterotopic liver of the jejunum confirmed by electron microscopy in a 2-year-old girl is described. We review the literature regarding heterotopic liver and discuss its embryogenesis. We suggest that in our case, there was trapping of hepatocyte-destined mesenchyme prior to biliary tree development. ...

journal_title：Journal of clinical gastroenterology

authors： Newland JR,Markin RS,Wilson RB,Jones JW

更新日期：1989-08-01 00:00:00

abstract：GOALS:Assess acceptance and attitudes regarding telemanagement (HAT) in patients with inflammatory bowel disease (IBD). BACKGROUND:Noncompliance is a barrier to successful outcomes in patients with IBD. Novel methods for monitoring and assessing compliance are needed. STUDY:HAT consists of a laptop connected to a wei...

journal_title：Journal of clinical gastroenterology

authors： Cross RK,Arora M,Finkelstein J

更新日期：2006-03-01 00:00:00

abstract：:In view of therapeutic advances, we carried out meta-analysis of results from 18 randomized, controlled clinical studies to update a previous meta-analysis and to provide an overview of clinical trials involving treatment of functional dyspepsia. The studies were included only if they satisfied inclusion and exclusion...

journal_title：Journal of clinical gastroenterology

authors： Finney JS,Kinnersley N,Hughes M,O'Bryan-Tear CG,Lothian J

更新日期：1998-06-01 00:00:00

abstract：:We describe four patients with a benign hepatic malformation most consistent with the rarely described anomaly known as corset liver. Three of these patients were extensively evaluated to rule out a malignancy because of an abdominal mass. These patients illustrate several features which may help in making the diagnos...

journal_title：Journal of clinical gastroenterology

authors： Philips DM,LaBrecque DR,Shirazi SS

更新日期：1985-08-01 00:00:00