A case of cyclosporine-sensitive, steroid-resistant, autoimmune chronic active hepatitis.

Abstract:

:Few alternative treatments are available for those patients with autoimmune chronic active hepatitis who fail to respond to the conventional treatment of corticosteroids. Such patients have a poor prognosis and frequently require liver transplantation. We report a patient with autoimmune hepatitis who failed treatment with corticosteroids and azathioprine. He responded to treatment with cyclosporine but relapsed with its discontinuation; reinstitution of the cyclosporine again induced remission. Cyclosporine appears to be an effective alternative treatment in patients with steroid-resistant, autoimmune chronic active hepatitis; its use may preclude or delay liver transplantation.

journal_name

J Clin Gastroenterol

authors

Person JL,McHutchison JG,Fong TL,Redeker AG

doi

10.1097/00004836-199312000-00012

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

317-20

issue

4

eissn

0192-0790

issn

1539-2031

journal_volume

17

pub_type

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