Fecal microbiota transplantation inducing remission in Crohn's colitis and the associated changes in fecal microbial profile.

Abstract:

:Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the intestine of unclear etiology. Increasing evidence has pointed to intestinal dysbiosis as a potential factor in a genetically susceptible individual. Fecal microbiota transplantation (FMT) has been used to treat inflammatory bowel disease with variable degrees of success. Herein, we report a patient with Crohn's colitis, previously failing an immunosuppressant, who achieved clinical, endoscopic, and histologic remission after a single fecal microbiota transplantation infusion. We have further characterized the changes in the fecal microbiota associated with this observation.

journal_name

J Clin Gastroenterol

authors

Kao D,Hotte N,Gillevet P,Madsen K

doi

10.1097/MCG.0000000000000131

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

625-8

issue

7

eissn

0192-0790

issn

1539-2031

journal_volume

48

pub_type

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