Helicobacter pylori infection and related gastrointestinal diseases.

Abstract:

:Helicobacter pylori has been implicated in the pathogenesis of a number of digestive tract disorders, such as chronic active gastritis, peptic ulceration, gastric cancer, and mucosa-associated lymphoid tissue lymphoma. Disease outcome is dependent on many factors, including bacterial genotype, host physiology and genetics, and environmental factors such as diet. Researchers continue to explore the complexities of H. pylori infection, seeking to explain why some individuals have asymptomatic infection, whereas others experience clinical disease. The importance of treating H. pylori infection in patients with gastrointestinal problems has been confirmed in recent years, with clinical trials showing that cure of infection can prevent duodenal ulcer and, to a lesser extent, gastric ulcer recurrence; cure early stage mucosa-associated lymphoid tissue lymphoma; and reduce the chances of developing gastric cancer in high-risk individuals.

journal_name

J Clin Gastroenterol

authors

Makola D,Peura DA,Crowe SE

doi

10.1097/MCG.0b013e318030e3c3

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

548-58

issue

6

eissn

0192-0790

issn

1539-2031

pii

00004836-200707000-00003

journal_volume

41

pub_type

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