Mechanisms of gastric mucosal injury and protection.

abstract：:Chronic hepatitis B virus (HBV) infection due to mother-to-child transmission during the perinatal period remains an important global health problem. Despite standard passive-active immunoprophylaxis with hepatitis B immunoglobulin and hepatitis B vaccine in neonates, up to 8.5% of newborns still acquire HBV infection...

journal_title：Journal of clinical gastroenterology

authors： Li J,Chang MS,Tran TT,Nguyen MH

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To assess the therapeutic efficacy of 5-aminosalicylic acid (5-ASA) in patients with colonic diverticular disease performing a systematic review of the literature. DATA SOURCES:Cochrane Trial Register (until Issue 4, 2008), Medical Literature Analysis and Retrieval System Online (1966 to October 1, 2008), Ex...

journal_title：Journal of clinical gastroenterology

authors： Gatta L,Vakil N,Vaira D,Pilotto A,Curlo M,Comparato G,Leandro G,Ferro U,Lera M,Milletti S,Di Mario F

更新日期：2010-02-01 00:00:00

abstract：:The fear of cancer has evoked calls for intensive surveillance programs in Barrett's esophagus. Two evolving issues are fueling this fire: (a) the rising risk of adenocarcinoma of the esophagus over the past 20 years and (b) the coincidental increase in the recognized prevalence of Barrett's esophagus in the general p...

journal_title：Journal of clinical gastroenterology

authors： Richter JE,Falk GW

更新日期：1996-09-01 00:00:00

abstract：GOALS:To determine the proportion of patients with gastroesophageal reflux disease who are on proton pump inhibitors (PPIs) who could reduce their prior dosage by half, and identify predictors of successful step-down. BACKGROUND:Appropriate hypergastrinemia results from gastric acid inhibition. A gender difference in ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Metz DC,Lund SH,Gizurarson S,Jacobsen EI,Asgeirsdóttir GA,Yngadóttir Y,Björnsson ES

更新日期：2017-07-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) affects approximately 30% of adults and 20% of children in the United States. Nonalcoholic steatohepatitis (NASH) is its most severe histologic form and progresses to cirrhosis in 20% of these patients. Once developed, 30% to 40% of patients with NASH cirrhosis will experience ...

journal_title：Journal of clinical gastroenterology

authors： McCullough AJ

更新日期：2006-03-01 00:00:00

abstract：:Endoscopic placement of nasoenteric feeding tubes is a common technique used in clinical practice. However, use of the endoscopic "drag and pull" method to pull the tube into position by grasping the feeding tube with a biopsy forceps requires considerable skill. In this paper, we describe a modified suture, which mar...

journal_title：Journal of clinical gastroenterology

authors： Chang WK,McClave SA,Chao YC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Spiral enteroscopy (SE) has emerged as a new alternative for deep intubation of the small intestine. SE is most often used to evaluate abnormal findings on capsule endoscopy (CE). OBJECTIVE:Investigate the ability of SE to reproduce abnormal findings detected on preceding CE. DESIGN:Prospective study. SET...

journal_title：Journal of clinical gastroenterology

authors： Buscaglia JM,Richards R,Wilkinson MN,Judah JR,Lam Y,Nagula S,Draganov PV

更新日期：2011-04-01 00:00:00

abstract：GOALS:To compare the healthcare resource consumption of patients who have irritable bowel syndrome (IBS) with an age-, gender-, and comorbidity-matched cohort of patients without IBS from a managed care perspective. STUDY:Retrospective cohort analysis. Data were obtained electronically through the Henry Ford Health Sy...

journal_title：Journal of clinical gastroenterology

authors： Patel RP,Petitta A,Fogel R,Peterson E,Zarowitz BJ

更新日期：2002-07-01 00:00:00

abstract：:We reviewed the initial lipid and fat-soluble vitamin levels in 56 patients with primary sclerosing cholangitis (PSC) enrolled in a randomized, placebo-controlled trial evaluating ursodeoxycholic acid. We also evaluated lipid and vitamin levels in a group of 87 patients with advanced PSC being evaluated for liver tran...

journal_title：Journal of clinical gastroenterology

authors： Jorgensen RA,Lindor KD,Sartin JS,LaRusso NF,Wiesner RH

更新日期：1995-04-01 00:00:00

abstract：:The advent of new diagnostic and therapeutic modalities for Helicobacter pylori allows any physician to offer curative antibiotic regimens to patients with peptic ulcer disease and gastritis. This article describes new management strategies and discusses the advantages of each. In the old strategy, endoscopy was perfo...

journal_title：Journal of clinical gastroenterology

authors： Marshall BJ

更新日期：1995-01-01 00:00:00

abstract：:Peutz-Jeghers syndrome is a malignancy-associated polyposis syndrome. We describe a histopathologic phenomenon easily encountered when examining the nature of Peutz-Jeghers polyps but that is underreported in the literature. This phenomenon of "pseudo-invasion" may mimic invasive carcinoma due to epithelial displaceme...

journal_title：Journal of clinical gastroenterology

authors： Westerman AM,van Velthuysen ML,Bac DJ,Schouten WR,Wilson JH

更新日期：1997-07-01 00:00:00

abstract：:Repeated surgical interventions on the biliary ductal system increase morbidity and mortality, particularly in the geriatric patient. In an attempt to prevent these complications, side-to-side choledochoduodenostomy was performed as the primary operative procedure in 54 patients, age 72 +/- 13 years. This was the pati...

journal_title：Journal of clinical gastroenterology

authors： Berlatzky Y,Freund HR

更新日期：1990-08-01 00:00:00

abstract：:A 24-year-old man with addisonian pernicious anemia, adult celiac disease and selective IgA deficiency is presented to emphasize the differential diagnosis of vitamin B12 deficient megaloblastic anemia in association with small intestinal mucosal abnormalities and the relationships between immunoglobulin deficiency, p...

journal_title：Journal of clinical gastroenterology

authors： Quigley EM,Carmichael HA,Watkinson G

更新日期：1986-06-01 00:00:00

abstract：:Jejunal varices were a cause of recurrent gastrointestinal hemorrhage in an 18-year-old man with common variable immunodeficiency and nodular lymphoid hyperplasia of the small intestine. Despite numerous procedures, including upper gastrointestinal endoscopy, colonoscopy, arteriography, and exploratory laparotomy no a...

journal_title：Journal of clinical gastroenterology

authors： Freiman JS,Gallagher ND

更新日期：1985-10-01 00:00:00

abstract：:We report a patient with long-standing ulcerative colitis who developed carcinoma of the colon, sclerosing cholangitis, pericholangitis, and bronchiectasis over the course of 10-15 years. Occurrence of these rare conditions in the same patient supports their reported association and reemphasizes that there may be mult...

journal_title：Journal of clinical gastroenterology

authors： Pang JA,Vicary FR

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND/GOALS:The endoscopic treatment of ampullary adenomas is established; however, the false-negative rate of endoscopic biopsy for carcinoma is 20% to 30%, and it remains uncertain whether identifiable features predict malignancy. Our aim in this study was to evaluate the predictable factors of malignancy in amp...

journal_title：Journal of clinical gastroenterology

authors： Kim HN,Kim KM,Shin JU,Lee JK,Lee KT,Lee KH,Kim KM,Lim JH

更新日期：2013-04-01 00:00:00

abstract：:Since the first fiberoptic instruments, gastrointestinal endoscopy has shaped the field of gastroenterology and is now a key diagnostic and therapeutic tool. Compared with the initial fiberoptic endoscopes state-of-the-art optical chips (or charge-coupled device technology) allowed a quantum leap in image quality. Des...

journal_title：Journal of clinical gastroenterology

authors： Holtmann GJ,Huelsen A,Shah A,Hourigan LF,Morrison M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:although azathioprine (AZA) is an effective immunomodulator in treating Crohn's disease, some patients develop leukopenia and risk severe infections. Thiopurine methyltransferase (TPMT) is an enzyme responsible for the metabolism of AZA, and its activity is inversely related to the risk of developing acute l...

journal_title：Journal of clinical gastroenterology

authors： Regueiro M,Mardini H

更新日期：2002-09-01 00:00:00

abstract：GOALS:To evaluate management, outcome, and follow-up of patients with sporadic duodenal adenomas and assess the presence of colorectal neoplasms. BACKGROUND:With the widespread use of esophagogastroduodenoscopy, an increasing number of sporadic duodenal adenomas are diagnosed. An optimal algorithm for management has n...

journal_title：Journal of clinical gastroenterology

authors： van Heumen BW,Mul K,Nagtegaal ID,van Kouwen MC,Nagengast FM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The sensitivity and specificity of current antihuman tissue transglutaminase (tTG) IgA assays used to detect celiac disease reportedly approach 100%. In addition, the sensitivity of new generation deamidated gliadin peptide (alpha-DGP) antibody assays has also been reported to be similar to the tTG IgA assay...

journal_title：Journal of clinical gastroenterology

authors： Naiyer AJ,Hernandez L,Ciaccio EJ,Papadakis K,Manavalan JS,Bhagat G,Green PH

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Nocturnal gastroesophageal reflux disease (GERD) has been associated with severe complications including erosive esophagitis, peptic stricture, and even esophageal adenocarcinoma and is known to cause a decreased health-related quality of life. However, there is limited information on independent predictors ...

journal_title：Journal of clinical gastroenterology

authors： Gaddam S,Maddur H,Wani S,Gupta N,Singh M,Singh V,Moloney B,Puli SR,Rastogi A,Bansal A,Sharma P

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To manage hepatocellular carcinoma (HCC) patients surviving for a long term, the treatment strategy for recurrent cancer is as important as that for the initial treatment. However, no prognostic scoring system has been available for patients with HCC recurrence. The purpose of this study was to develop a new ...

journal_title：Journal of clinical gastroenterology

authors： Toyama T,Hiramatsu N,Yakushijin T,Oze T,Nakanishi F,Yasumaru M,Mochizuki K,Kanto T,Takehara T,Kasahara A,Hayashi N

更新日期：2008-03-01 00:00:00

abstract：:To investigate the influence of the brain-gut interactions on the pathophysiology of irritable bowel syndrome (IBS), we compared such patients (n = 10) with healthy control subjects (n = 11) by measuring the pressure of the colon and small intestine simultaneously with analysis of power spectrum of the electroencephal...

journal_title：Journal of clinical gastroenterology

authors： Fukudo S,Nomura T,Muranaka M,Taguchi F

更新日期：1993-09-01 00:00:00

abstract：:In view of therapeutic advances, we carried out meta-analysis of results from 18 randomized, controlled clinical studies to update a previous meta-analysis and to provide an overview of clinical trials involving treatment of functional dyspepsia. The studies were included only if they satisfied inclusion and exclusion...

journal_title：Journal of clinical gastroenterology

authors： Finney JS,Kinnersley N,Hughes M,O'Bryan-Tear CG,Lothian J

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:The prevalence of duodenal ulcer (DU) has been considered high in patients with chronic pancreatitis; however, its pathogenesis is unclear. We hypothesized that Helicobacter pylori infection plays the major pathogenetic role. STUDY:One hundred seven cases (97 men, 10 women) of chronic alcoholic pancreatitis...

journal_title：Journal of clinical gastroenterology

authors： Chebli JM,de Souza AF,Gaburri PD,Bastos KV,Ribeiro TC,Filho RJ,Chebli LA,Castro Ferreira LE

更新日期：2002-07-01 00:00:00

abstract：:The term indeterminate colitis (IC) is an interim, or preliminary, descriptive term used by pathologists for cases of inflammatory bowel disease (IBD) in which a definite diagnosis of ulcerative colitis (UC) or Crohn's disease (CD) cannot be established based on the information available at the time of surgical sign-o...

journal_title：Journal of clinical gastroenterology

authors： Odze RD

更新日期：2004-05-01 00:00:00

abstract：:The esophagogastric junction (EGJ) is a complex barrier between the thoracic and abdominal luminal gut compartments, comprised primarily of the lower esophageal sphincter (LES) and crural diaphragm. Although closed at rest, the EGJ relaxes to allow antegrade bolus transit and retrograde venting of air. Abnormal relaxa...

journal_title：Journal of clinical gastroenterology

authors： Rogers BD,Gyawali CP

更新日期：2021-02-01 00:00:00

abstract：:Between 1978 and 1989, 13 of 48 patients with anomalous union of the pancreaticobiliary ductal system (AUPBD) were diagnosed as having acute pancreatitis. We have studied the clinical, radiologic, and surgical features of these 13 patients. A transient rise in the intraductal pressure of the pancreatic duct during an ...

journal_title：Journal of clinical gastroenterology

authors： Mori K,Nagakawa T,Ohta T,Nakano T,Kadoya N,Kayahara M,Kanno M,Akiyama T,Ueno K,Konishi I

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND/AIM:We investigated changes in hepatitis B surface antigen (HBsAg) level and its correlation with clinical outcomes in treatment-naive chronic hepatitis B (CHB) patients undergoing entecavir therapy. PATIENTS AND METHODS:Among 51 hepatitis B e antigen (HBeAg)-positive treatment-naive CHB patients receiving ...

journal_title：Journal of clinical gastroenterology

authors： Jung YK,Kim JH,Lee YS,Lee HJ,Yoon E,Jung ES,Hong SK,Joo MK,Yeon JE,Park JJ,Kim JS,Bak YT,Byun KS

更新日期：2010-10-01 00:00:00

abstract：:We evaluated, in a randomized double-blind trial, the efficacy of oral paromomycin sulfate administration in the prevention of endotoxemia in 24 cirrhotic patients with endotoxemia. Renal function was evaluated by glomerular-filtration rate and renal plasma flow at the beginning and at the end of the study period. Aft...

journal_title：Journal of clinical gastroenterology

authors： Tarao K,Moroi T,Hirabayashi Y,Ikeuchi T,Endo O,Takamura Y

更新日期：1982-06-01 00:00:00