Abstract:
:The main issue regarding the approach to the patient with uninvestigated dyspepsia is whether the symptoms are the result of an important clinical illness, which then determines the appropriate management strategy for the treatment of the symptoms. An initial trial of empiric antisecretory drugs is recommended for those without Helicobacter pylori infection and no alarm symptoms, whereas H. pylori eradication is recommended for those with an active H. pylori infection. Treatment expectations for H. pylori infections should theoretically be similar to other common infectious diseases. In most regions, clarithromycin resistance has undermined traditional triple therapy so that it is no longer a suitable choice as an empiric therapy. Four drug therapies, such as sequential, concomitant, and bismuth-quadruple therapy are generally still acceptable choices as empiric therapies. Posteradication testing is highly recommended to provide early identification of otherwise unrecognized increasing antimicrobial resistance. However, despite the ability to successfully cure H. pylori infections, a symptomatic response can be expected in only a minority of those with dyspepsia not associated with ulcers (so called nonulcer dyspepsia). Overall, from the patients stand point, symptomatic relief is often difficult to achieve and physicians must rely on reassurance along with empiric and individualized care.
journal_name
J Clin Gastroenteroljournal_title
Journal of clinical gastroenterologyauthors
Graham DY,Rugge Mdoi
10.1097/MCG.0b013e3181c64c69subject
Has Abstractpub_date
2010-03-01 00:00:00pages
167-72issue
3eissn
0192-0790issn
1539-2031journal_volume
44pub_type
杂志文章,评审abstract:BACKGROUND:Hepatitis C virus (HCV) infection is prevalent in Latinos. There is some evidence that progression to cirrhosis is more rapid. END POINTS:To calculate time of cirrhosis from time of HCV infection in a large Latino population. Other end points were to assess variables that predict cirrhosis and the effect of...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/01.mcg.0000210105.66994.dc
更新日期:2006-04-01 00:00:00
abstract:GOALS:We sought to determine if providers who have higher standards for optimal bowel preparation might be more fastidious in their examination of the colon and, therefore, have higher adenoma detection rates (ADRs). BACKGROUND:ADRs are a reliable and objective marker of colonoscopy performance. Suboptimal bowel prepa...
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更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Although the efficacy of tacrolimus for inducing remission of refractory ulcerative colitis (UC) is established, its efficacy for maintaining remission of UC has not been evaluated. AIM:The aim of this study was to evaluate the efficacy of tacrolimus compared with thiopurines for maintaining remission in pa...
journal_title:Journal of clinical gastroenterology
pub_type: 临床试验,杂志文章
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更新日期:2011-07-01 00:00:00
abstract::A 54-year-old man with chronic hepatitis C virus (HCV) developed quadrihemianopsia caused by lacunar brain infarction. Extensive evaluation revealed high titers of anticardiolipin antibodies (ACA). Following interferon treatment (6 x 10(6), three times a week for 2 months and 3 x 10(6) for another 7 months), liver tra...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199701000-00009
更新日期:1997-01-01 00:00:00
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journal_title:Journal of clinical gastroenterology
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doi:10.1097/MCG.0b013e31828be6f0
更新日期:2013-07-01 00:00:00
abstract::The purpose of our study was to assess the effectiveness of computer-assisted instruction (CAI) in patients having colonoscopies. We conducted a randomized, controlled trial in large, multispecialty clinic. Eighty-six patients were referred for colonoscopies. The interventions were standard education versus standard e...
journal_title:Journal of clinical gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Guidelines recommend upper endoscopic screening of cirrhotic patients for gastroesophageal varices. Cirrhosis is not always distinguishable from chronic hepatitis. GOALS:To identify low-risk patients who can be spared upper endoscopy irrespective of a diagnosis of cirrhosis. STUDY:We evaluated 13 nonendosc...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0b013e318157464b
更新日期:2009-01-01 00:00:00
abstract:GOALS:To determine the incidence of renal function deterioration in adult patients with Salmonella infection. BACKGROUND:Renal impairment has been described during severe Salmonella infection and is mainly due to shock, dehydration, or rhabdomyolysis. However, it is unclear whether less severe Salmonella infection als...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
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更新日期:2006-11-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1994-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
abstract::Thirty-five consecutive patients with acute hematochezia, negative gastric aspirates, and negative sigmoidoscopy underwent urgent colonoscopy after Golytely purgation. Mucosal visualization was excellent. Colonic bleeding lesions were identified in 24 of 35 patients, and hemorrhage originating proximal to the ileoceal...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-198602000-00010
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Ascites due to cirrhosis may be difficult to distinguish from ascites due to heart failure by clinical features alone. More invasive testing is usually necessary, such as measurement of the hepatic venous pressure gradient, or paracentesis with measurement of the ascitic fluid total protein. AIM:The aim of ...
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pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mcg.0000128939.40458.25
更新日期:2004-07-01 00:00:00
abstract:GOALS:Assess neoplasia and polypectomy-related adverse event (AE) rates in gastric hyperplastic polyps (GHPs). BACKGROUND:GHPs carry a risk of neoplastic transformation. The rate of neoplastic transformation and the risk of polypectomy-related bleeding are unclear in the West, as data are derived from Asian or small s...
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pub_type: 杂志文章
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更新日期:2020-10-13 00:00:00
abstract::We report six cases of pseudolipoma of Glisson's capsule. The patients ranged from 53 to 83 years old (mean 67.7 years), and all were men. Pseudolipoma of Glisson's capsule was detected by imaging studies before operation in two cases, and noted incidentally in the remaining four. Computed tomography demonstrated a su...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract:GOALS:To determine whether the presence of dupA Helicobacter pylori (H. pylori) influences the cure rate of primary eradication therapy. BACKGROUND:Several virulence factors of H. pylori have been reported to affect the efficacy of the eradication rate. However, no study has investigated whether the presence of dupA a...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0b013e318243201c
更新日期:2012-04-01 00:00:00
abstract::Autoantibodies are nonpathogenic manifestations of immune reactivity, and they may occur in acute and chronic liver diseases. Autoantibodies may be consequences rather than causes of the liver injury, and they should be regarded as diagnostic clues rather than etiologic markers. Conventional autoantibodies used in the...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/00004836-200310000-00011
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:There was some ambiguity in the recent guidelines on the use of capsule endoscopy (CE) in cases of iron deficiency anemia (IDA). GOAL:We aimed to examine the yield of CE in diagnosing the cause of IDA and to define clinical parameters that predict higher diagnostic yields. MATERIALS AND METHODS:A total of ...
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pub_type: 杂志文章
doi:10.1097/MCG.0000000000001255
更新日期:2020-05-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::In this report, we present a patient with chronic hepatitis C-associated cryoglobulinemia who was kept on maintenance interferon treatment because of flare-ups in cryoglobulinemia-associated signs and hepatitis after withdrawal, dose reduction, and increase in dose intervals of interferon. This type of interferon use ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-200110000-00015
更新日期:2001-10-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2019-03-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-198502000-00002
更新日期:1985-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/00004836-198912000-00003
更新日期:1989-12-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-198804000-00023
更新日期:1988-04-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
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更新日期:2010-11-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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更新日期:2006-04-01 00:00:00
abstract:GOALS:To assess the effect of unilateral versus bilateral lung transplantation (LTx) on esophageal motility and gastroesophageal reflux, and the association with the development of obstructive chronic lung allograft dysfunction (o-CLAD). BACKGROUND:We have shown that esophagogastric junction outflow obstruction, incom...
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pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
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更新日期:2001-03-01 00:00:00
abstract::Gastroesophageal reflux disease, especially when refractory to standard therapy, remains a significant clinical problem. Although symptom pathogenesis in erosive reflux disease is relatively easy to understand, it is less clear how exposure of the macroscopically normal mucosa in nonerosive reflux disease (NERD) is ab...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
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更新日期:2014-01-01 00:00:00