Usefulness of serum N-terminal-ProBNP in distinguishing ascites due to cirrhosis from ascites due to heart failure.

Abstract:

BACKGROUND:Ascites due to cirrhosis may be difficult to distinguish from ascites due to heart failure by clinical features alone. More invasive testing is usually necessary, such as measurement of the hepatic venous pressure gradient, or paracentesis with measurement of the ascitic fluid total protein. AIM:The aim of this study is to determine the diagnostic accuracy of serum NT-proBNP (N-terminal-pro-brain-type natriuretic peptide) in distinguishing patients with ascites from heart failure or cirrhosis. METHODS:Using a bank of previously collected fluid, we measured the serum and ascitic NT-proBNP levels in 58 patients with known cirrhosis, and 18 patients with known heart failure. Patients with both disease processes were excluded. The total protein levels in ascites was also measured and compared with serum NT-proBNP levels. RESULTS:The median serum NT-proBNP level was 165.7 pg/mL (range, 29.9 to 1795) in the cirrhosis group and 6100 pg/mL (range, 1110 to 116,248) in the heart failure group (P<0.001). Similar values were also found when using ascitic fluid NT-proBNP levels. Using a value of 1000 pg/mL, the sensitivity of serum NT-proBNP in ruling out cirrhosis as the cause for ascites was 100%. CONCLUSIONS:Serum NT-proBNP seems to be an extremely powerful marker in distinguishing ascites due to cirrhosis from ascites due to heart failure. Serum NT-proBNP may potentially replace the more invasive testing presently in use.

journal_name

J Clin Gastroenterol

authors

Sheer TA,Joo E,Runyon BA

doi

10.1097/MCG.0b013e318198113b

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

e23-6

issue

1

eissn

0192-0790

issn

1539-2031

journal_volume

44

pub_type

杂志文章
  • Endoscopic ultrasonography in multiple lymphomatous polyposis.

    abstract::Two cases of multiple lymphomatous polyposis (MLP) are presented, involving different segments of the gastrointestinal tract. Both cases display the characteristic clinical and pathologic features of MLP. In addition, we were able to document, for the first time, the endoscopic ultrasonographic findings in this diseas...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200202000-00010

    authors: Viana HL,Henrique RM,Ferreira ES,Correia AM,Silva RA,Dias LM,Viana RL

    更新日期:2002-02-01 00:00:00

  • The effect of octreotide as an adjunct treatment in active nonvariceal upper gastrointestinal bleeding.

    abstract:GOALS:The aim of this study was to determine the effect ofoctreotide on active or recent gastrointestinal bleeding from benign peptic ulcers. STUDY:This is a prospective, randomized study including 110 patients with gastric or duodenal peptic ulcers presenting with active spurting or oozing bleeding or nonbleeding vis...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-200403000-00009

    authors: Nikolopoulou VN,Thomopoulos KC,Katsakoulis EC,Vasilopoulos AG,Margaritis VG,Vagianos CE

    更新日期:2004-03-01 00:00:00

  • Crohn's disease in the elderly.

    abstract::We compared eleven patients in whom symptoms of Crohn's disease appeared at age greater than or equal to 65 with a younger group in whom symptoms had appeared earlier. Only 64% of the older patients were initially recognized as having Crohn's disease, as compared with 96% of the younger patients even though clinical c...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198908000-00013

    authors: Stalnikowicz R,Eliakim R,Diab R,Rachmilewitz D

    更新日期:1989-08-01 00:00:00

  • Cetirizine-induce cholestasis.

    abstract::Cetirizine, a human metabolite of hydroxyzine, is a selective H1-receptor antagonist currently approved for the treatment of seasonal allergic rhinitis, perennial allergic rhinitis, and chronic urticaria. In U.S. clinical trials, transient reversible hepatic transaminase elevations were observed in <2% of patients dur...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200010000-00016

    authors: Fong DG,Angulo P,Burgart LJ,Lindor KD

    更新日期:2000-10-01 00:00:00

  • Cytomegalovirus gastritis associated with pseudolymphoma.

    abstract::A man who previously had several episodes of upper gastrointestinal hemorrhage from erosive gastritis developed recurrent hemorrhage. Endoscopy showed punctate hemorrhages in the fundus and body of the stomach, plus a discrete area of thickened folds in the anterior wall. Biopsies revealed a dense mucosal infiltrate t...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/00004836-199404000-00011

    authors: Zucker GM,Otis C,Korowski K,Navab F

    更新日期:1994-04-01 00:00:00

  • Does duodenal ulcer lead to an early diagnosis of gastric cancer?

    abstract::In four of five patients with gastric cancer who also had a chronic duodenal ulcer, the histologic type was "early gastric cancer," which offers a better prognosis than the more common type. Patients with duodenal ulcer who develop gastric cancer may have a better prognosis than patients with gastric cancer without du...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198702000-00009

    authors: Neeman A,Shoenfeld Y,Kadish U

    更新日期:1987-02-01 00:00:00

  • Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease.

    abstract::6-mercaptopurine (6-MP) and azathioprine (AZA) are used to treat inflammatory bowel disease (IBD). Side effects include infection, leukopenia, hepatitis, and pancreatitis. The level of thiopurine methyltransferase (TPMT), which metabolizes 6-MP to 6-methylmercaptopurine, may reflect the risk of side effects. We sought...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200006000-00011

    authors: Kader HA,Wenner WJ Jr,Telega GW,Maller ES,Baldassano RN

    更新日期:2000-06-01 00:00:00

  • The risk of bleeding after percutaneous liver biopsy: relation to platelet count.

    abstract::We sought to define the risk of bleeding after percutaneous aspiration liver biopsy in patients with low platelet counts but otherwise normal clotting factors. Eighty-seven patients underwent liver biopsy using the Menghini 1-second technique with either a 1.6-mm or a 1.2-mm needle. Bleeding occurred in three out of 1...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198210000-00011

    authors: Sharma P,McDonald GB,Banaji M

    更新日期:1982-10-01 00:00:00

  • Gastrointestinal and hepatic manifestations of Sjogren syndrome.

    abstract::Sjogren syndrome (SS) is an autoimmune disease that affects exocrine glands and therefore may affect the gastrointestinal system, from the mouth, esophagus, and bowel to the liver and pancreas. Oral involvement in SS is mainly characterized by dryness, with a wide spectrum of symptoms, from mild-to-severe xerostomia w...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0b013e3182329d9c

    authors: Ebert EC

    更新日期:2012-01-01 00:00:00

  • Penetrating duodenal ulcer from hepatic artery chemotherapy infusion catheter. Successful conservative medical management.

    abstract::A 45-year-old woman receiving continuous infusions of 5-fluoro-2'-deoxy-uridine into the hepatic artery through a surgically implanted intraarterial catheter for hepatic metastases from adenocarcinoma of the colon, developed acute epigastric pain and anemia. Endoscopy demonstrated a duodenal ulcer with a portion of th...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198808000-00016

    authors: Hutchins LF,Webb RT,Ortego TJ,Lang NP,Navab F

    更新日期:1988-08-01 00:00:00

  • Quality of Sleep and Coexistent Psychopathology Have Significant Impact on Fatigue Burden in Patients With Inflammatory Bowel Disease.

    abstract:BACKGROUND:Fatigue is common in inflammatory bowel disease (IBD) patients and is associated with factors such as psychopathology, sleep quality, and disease activity. GOAL:To investigate the combined role of all the above factors in the burden of fatigue among IBD patients. STUDY:We conducted an observational study o...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000729

    authors: Hashash JG,Ramos-Rivers C,Youk A,Chiu WK,Duff K,Regueiro M,Binion DG,Koutroubakis I,Vachon A,Benhayon D,Dunn MA,Szigethy EM

    更新日期:2018-05-01 00:00:00

  • Irritable bowel syndrome subtypes defined by Rome II and Rome III criteria are similar.

    abstract:BACKGROUND:The implications of the Rome III recommendations to change the irritable bowel syndrome (IBS) subtype criteria for stool pattern are unknown. AIM:(1) Determine the level of agreement between Rome II and Rome III subtypes and (2) compare the behaviors of Rome II and Rome III subtypes over time. METHODS:Fema...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e31815bd749

    authors: Dorn SD,Morris CB,Hu Y,Toner BB,Diamant N,Whitehead WE,Bangdiwala SI,Drossman DA

    更新日期:2009-03-01 00:00:00

  • Hepatocellular carcinoma: the high-risk patient.

    abstract::Hepatocellular carcinoma (HCC) is the most common hepatic malignancy worldwide. The primary risk factor for the development of HCC is cirrhosis. Even patients without cirrhosis who develop HCC are typically found to have some underlying hepatic abnormality, such as steatohepatitis or chronic viral hepatitis. Although ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/00004836-200211002-00003

    authors: Nissen NN,Martin P

    更新日期:2002-11-01 00:00:00

  • Histologic findings and Helicobacter pylori in duodenal biopsies.

    abstract::We have studied the morphologic aspects of the duodenal bulb in relation to Helicobacter pylori infection in a large group of patients with endoscopically assessed duodenitis to learn more about the pathogenesis of nonspecific duodenitis (bulbitis) and to clarify the specific role of H. pylori. Eight duodenal biopsy s...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199801000-00020

    authors: Caselli M,Gaudio M,Chiamenti CM,Trevisani L,Sartori S,Saragoni L,Boldrini P,Dentale A,Ruina M,Alvisi V

    更新日期:1998-01-01 00:00:00

  • Inadequate Bowel Cleansing Efficacy of Split-dose Polyethylene Glycol for Colonoscopy in Type 2 Diabetic Patients: A Prospective and Blinded Study.

    abstract:BACKGROUND/AIMS:Split-dose polyethylene glycol (PEG) is considered a standard bowel preparation regimen for colonoscopy in the general population. However, it is not clear whether the regimen is optimal for colonoscopy in diabetic patients. The aim of this study was to compare the efficacy and tolerability of split-dos...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MCG.0000000000000536

    authors: Kim YH,Seo EH,Lee JS,Lee SH,Park HS,Choi SH,Park JY,Lee CW

    更新日期:2017-03-01 00:00:00

  • Primary gastrointestinal follicular lymphoma: a clinicopathologic study of 13 cases from Taiwan.

    abstract:GOALS:Follicular lymphoma (FL) is a common nodal lymphoma. Primary gastrointestinal follicular lymphoma (GIFL) is rare and most commonly occurs in the elder women with indolent clinical course, mainly in the duodenum and terminal ileum. We conducted this study to characterize GIFL in Taiwan. STUDY:A total of 13 cases ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e3180f62b12

    authors: Huang WT,Hsu YH,Yang SF,Chuang SS

    更新日期:2008-10-01 00:00:00

  • Barrett esophagus: endoscopic findings and what to biopsy.

    abstract::Barrett esophagus (BE) is considered the precursor for nearly all cases of esophageal adenocarcinoma. The potential sequence from intestinal metaplasia to dysplasia to cancer can best be monitored by careful endoscopic observation and surveillance biopsies. The ability to diagnose BE, biopsy accurately, and appropriat...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/00004836-200305001-00003

    authors: Boyce HW

    更新日期:2003-05-01 00:00:00

  • Insulinoma after streptozotocin therapy for metastatic gastrinoma: natural history or iatrogenic complication?

    abstract::Islet cell carcinoma frequently produces more than one chemical product, although its clinical expression is usually restricted to a single hormone. We describe an unusual patient who presented with full-blown metastasizing gastrinoma. He was treated with cimetidine for five years and then streptozotocin therapy, whic...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199010000-00018

    authors: Bar M,Burke M,Isakov A,Almog C

    更新日期:1990-10-01 00:00:00

  • Emergency Department Burden of Gastroparesis in the United States, 2006 to 2013.

    abstract:BACKGROUND AND AIMS:Gastroparesis, a chronic gastrointestinal disorder defined by delayed stomach emptying in the absence of obstruction, is often associated with frequent and costly visits to the emergency department (ED). The aim of this study was to analyze trends in gastroparesis-related ED visits from 2006 to 2013...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000972

    authors: Hirsch W,Nee J,Ballou S,Petersen T,Friedlander D,Lee HN,Cheng V,Lembo A

    更新日期:2019-02-01 00:00:00

  • Epidemiology and Diagnosis of Gastroparesis in the United States: A Population-based Study.

    abstract:GOALS:We aimed to establish the epidemiological characteristics and documentation of diagnostic workup for gastroparesis (GP). BACKGROUND:No study has used a national database to evaluate the prevalence, demographics, and associated comorbid conditions of GP, and document rates of proper diagnosis. MATERIALS AND METH...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000001231

    authors: Syed AR,Wolfe MM,Calles-Escandon J

    更新日期:2020-01-01 00:00:00

  • Advances in Imaging of Diffuse Parenchymal Liver Disease.

    abstract::There are >1.5 billion people with chronic liver disease worldwide, causing liver diseases to be a significant global health issue. Diffuse parenchymal liver diseases, including hepatic steatosis, fibrosis, metabolic diseases, and hepatitis cause chronic liver injury and may progress to fibrosis and eventually hepatoc...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000001380

    authors: Ghadimi M,Habibabadi RR,Hazhirkarzar B,Shaghaghi M,Ameli S,Khoshpouri P,Ghasabeh MA,Gurakar A,Pawlik TM,Kamel IR

    更新日期:2020-09-01 00:00:00

  • Factors associated with failure of metronidazole in Clostridium difficile-associated disease.

    abstract:GOAL:To identify patients likely to fail metronidazole as initial treatment of C. difficile infection. BACKGROUND:For moderate to severe Clostridium difficile-associated diarrhea, metronidazole is the drug of choice for treatment. Oral vancomycin is given to patients who fail metronidazole or have intolerable side eff...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200405000-00005

    authors: Fernandez A,Anand G,Friedenberg F

    更新日期:2004-05-01 00:00:00

  • The symptomatic and histologic response to a gluten-free diet in patients with borderline enteropathy.

    abstract:GOALS:A clinical problem is posed by patients with symptoms suggestive of gluten sensitivity (diarrhea, weight loss, unresponsive iron-deficiency anemia, etc.); however, small intestinal biopsies reveal only minor abnormalities, such as lymphocytosis with or without crypt hyperplasia (Marsh I-II). Our aim was to assess...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200301000-00006

    authors: Tursi A,Brandimarte G

    更新日期:2003-01-01 00:00:00

  • Crohn's disease associated with autoimmune neutropenia.

    abstract::We report a 29-year-old woman with a 20-year history of Crohn's disease and neutropenia. Because of repeated complications of Crohn's disease, she has undergone three intestinal resections and also has had recurrent skin abscesses, sinusitis, and pneumonia. Persistent neutropenia has been noted throughout the course o...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199106000-00016

    authors: Stevens C,Peppercorn MA,Grand RJ

    更新日期:1991-06-01 00:00:00

  • Esophageal obstruction with a dietary fiber product designed for weight reduction.

    abstract::Supplements consisting primarily of dietary fibers are marketed as aids to weight reduction. Of uncertain efficacy, they have generally been regarded as safe when used according to directions. We report two cases of acute esophageal obstruction by a guar gum product in patients with preexisting esophageal abnormalitie...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199012000-00014

    authors: Opper FH,Isaacs KL,Warshauer DM

    更新日期:1990-12-01 00:00:00

  • The Role of Insulin-like Growth Factor (IGF) Axis in Early Diagnosis of Pancreatic Adenocarcinoma (PDAC).

    abstract::New-onset diabetes mellitus (DM) is one of the first symptoms of pancreatic adenocarcinoma (PDAC). The frequency of endocrine disorders is estimated between 40% and 80% in patients with pancreatic cancer. DM is a risk factor for cancer development but it may also be a consequence of the tumor growth. Data confirming t...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0000000000001073

    authors: Wlodarczyk B,Gasiorowska A,Malecka-Panas E

    更新日期:2018-08-01 00:00:00

  • HCV hepatitis associated with anticardiolipin antibody and a cerebrovascular accident. Response to interferon therapy.

    abstract::A 54-year-old man with chronic hepatitis C virus (HCV) developed quadrihemianopsia caused by lacunar brain infarction. Extensive evaluation revealed high titers of anticardiolipin antibodies (ACA). Following interferon treatment (6 x 10(6), three times a week for 2 months and 3 x 10(6) for another 7 months), liver tra...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199701000-00009

    authors: Malnick SD,Abend Y,Evron E,Sthoeger ZM

    更新日期:1997-01-01 00:00:00

  • Biliary giardiasis in a patient with human immunodeficiency virus.

    abstract::A 41-year-old man with human immunodeficiency virus (HIV) (CD4 count, 446/mm3) developed a protracted course of abdominal pain, weight loss, and increasing liver function tests after undergoing a metronidazole treatment regimen for Giardia enteritis. Three months later, endoscopic retrograde cholangiography (ERCP) sho...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200108000-00018

    authors: Aronson NE,Cheney C,Rholl V,Burris D,Hadro N

    更新日期:2001-08-01 00:00:00

  • Simplify the technique of nasoenteric feeding tube placement with a modified suture tie.

    abstract::Endoscopic placement of nasoenteric feeding tubes is a common technique used in clinical practice. However, use of the endoscopic "drag and pull" method to pull the tube into position by grasping the feeding tube with a biopsy forceps requires considerable skill. In this paper, we describe a modified suture, which mar...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Chang WK,McClave SA,Chao YC

    更新日期:2005-01-01 00:00:00

  • Development of hepatocellular carcinoma in a patient with chronic hepatitis C after 6 years of a sustained and complete response to IFN-alpha.

    abstract::The authors report a rare case of hepatocellular carcinoma (HCC) that developed 6 years after a sustained and complete response to interferon (IFN) therapy for chronic hepatitis C. A 61-year-old Japanese man presented with a mass in the liver that was diagnosed as HCC. Six years earlier he was treated with IFN-alpha a...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199909000-00024

    authors: Yamaguchi K,Omagari K,Kinoshita H,Yoshioka S,Furusu H,Takeshima F,Nanashima A,Yamaguchi H,Kohno S

    更新日期:1999-09-01 00:00:00