Consider the perspectives: interventional radiology.


:Image-guided percutaneous local and regional modalities are major treatments for hepatocellular carcinoma. Patients having better liver function and performance are usually eligible and can gain significant survival benefit, especially with more limited tumor burden. The most common local therapies are ethanol and radiofrequency ablation, with the latter providing better local tumor control and survival. Radiofrequency ablation has also occasionally been found to be equivalent to surgical resection for appropriate tumors, with additionally lower morbidity. Chemoembolization is the prevalent transarterial therapy and has been shown to increase survival compared with conservative management. Chemoembolization using drug-eluting beads and radioembolization with β-emitting yttrium-90 microspheres seems to reduce side effects and expand the pool of eligible patients, whereas controversy remains regarding the role of bland particle embolization. Combinations of local and regional therapies may be appropriate for treating a particular tumor or different tumors over time and they may be combined with surgical and medical options.


J Clin Gastroenterol


Pollak JS




Has Abstract


2013-07-01 00:00:00








47 Suppl


  • Reversing Hyperammonemia in Neuroendocrine Tumors.

    abstract::Ammonia is a neurotoxin that is normally cleared by the intact liver and if not, hyperammonemia results in hepatic encephalopathy. Hyperammonemia may be owing to primary or secondary causes. Early diagnosis is important to prevent permanent brain damage. Advanced malignancy involving the liver is associated with hyper...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Broadbridge V,Townsend A,Pittman K,Kimber R,Patterson W,Sukumaran S,Price TJ

    更新日期:2010-09-01 00:00:00

  • Hepatoblastoma presenting as isosexual precocity. The clinical importance of histologic and serologic parameters.

    abstract::A 2-year-old boy presented with sexual precocity secondary to a hormone-producing hepatoblastoma. The tumor demonstrated an aggressive histologic pattern and stained immunohistochemically for alpha-fetoprotein and beta-subunit human chorionic gonadotrophin. After a successful liver transplant these tumor markers were ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Heimann A,White PF,Riely CA,Ritchey AK,Flye MW,Barwick KW

    更新日期:1987-02-01 00:00:00

  • Celiac sprue-associated immune complex glomerulonephritis.

    abstract::A 35-year-old man developed leg edema, marked hypoalbuminemia, and proteinuria. Subsequent renal biopsy revealed a diffuse membranoproliferative glomerulonephritis and, on electron microscopy, typical electron-dense deposits characteristic of an immune complex pathogenesis. Although protein wasting might have readily ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Scholey J,Freeman HJ

    更新日期:1986-04-01 00:00:00

  • Quality of Sleep and Coexistent Psychopathology Have Significant Impact on Fatigue Burden in Patients With Inflammatory Bowel Disease.

    abstract:BACKGROUND:Fatigue is common in inflammatory bowel disease (IBD) patients and is associated with factors such as psychopathology, sleep quality, and disease activity. GOAL:To investigate the combined role of all the above factors in the burden of fatigue among IBD patients. STUDY:We conducted an observational study o...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Hashash JG,Ramos-Rivers C,Youk A,Chiu WK,Duff K,Regueiro M,Binion DG,Koutroubakis I,Vachon A,Benhayon D,Dunn MA,Szigethy EM

    更新日期:2018-05-01 00:00:00

  • New regulatory trends for probiotics.

    abstract::The aim of this paper (presented in Rome, Italy, at the 2nd Congress of Probiotics, Prebiotics, and New Food, September 7-9, 2003) was to provide an objective view of the regulatory trends at the European level specifically referring to probiotics, because until now they have never been directly mentioned nor official...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Prevot MB

    更新日期:2004-07-01 00:00:00

  • Pneumatosis cystoides intestinalis in AIDS-associated cryptosporidiosis. More than an incidental finding?

    abstract::A 34-year-old man with acquired immunodeficiency syndrome (AIDS) developed pneumatosis cystoides intestinalis associated with an intestinal infection with Cryptosporidium organisms. The pneumatosis resolved upon treatment of the cryptosporidiosis with paromomycin and clofazimine. Four other cases of benign pneumatosis...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Samson VE,Brown WR

    更新日期:1996-06-01 00:00:00

  • Co-occurrence of hepatocellular carcinoma and lymphoma in patients with hepatitis C virus cirrhosis.

    abstract::The association of hepatitis C virus (HCV) with neoplasia is not completely understood. Hepatitis C virus is hepatolymphotrophic. It is considered an inducing factor of hepatocellular carcinoma (HCC) and is associated with various types of lymphomas. We describe a patient with HCV cirrhosis who developed gastric lymph...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Shapira MY,Muszkat M,Braunstein I,Gotsman I

    更新日期:2001-04-01 00:00:00

  • Silent celiac disease in chronic hepatitis C: impact of interferon treatment on the disease onset and clinical outcome.

    abstract:GOALS:To assess the impact of interferon treatment on celiac disease onset in hepatitis C patients and to clarify its clinical relevance and outcome. BACKGROUND:Hepatitis C is associated with autoimmunity, which can be exacerbated by interferon treatment. Cases of celiac disease activation during interferon treatment ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Durante-Mangoni E,Iardino P,Resse M,Cesaro G,Sica A,Farzati B,Ruggiero G,Adinolfi LE

    更新日期:2004-11-01 00:00:00

  • Cannabinoids: A Guide for Use in the World of Gastrointestinal Disease.

    abstract::Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, cannabinoid receptors 1 and 2, are found on cells of various tissues, with...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Unal E,Anderson B,Helber A,Marks JH

    更新日期:2020-10-01 00:00:00

  • Mechanisms of action of sucralfate.

    abstract::Sucralfate binds to duodenal and gastric ulcers and to gastric erosions produced by ethanol and anti-inflammatory drugs. The affinity of sucralfate for defective mucosa is explained by the drug's viscous adhesiveness and the formation of polyvalent bridges between the negatively charged sucralfate polyanions and posit...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Nagashima R

    更新日期:1981-01-01 00:00:00

  • Efficacy of 5-ASA in the treatment of colonic diverticular disease.

    abstract:OBJECTIVE:To assess the therapeutic efficacy of 5-aminosalicylic acid (5-ASA) in patients with colonic diverticular disease performing a systematic review of the literature. DATA SOURCES:Cochrane Trial Register (until Issue 4, 2008), Medical Literature Analysis and Retrieval System Online (1966 to October 1, 2008), Ex...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审


    authors: Gatta L,Vakil N,Vaira D,Pilotto A,Curlo M,Comparato G,Leandro G,Ferro U,Lera M,Milletti S,Di Mario F

    更新日期:2010-02-01 00:00:00

  • Long-term symptom patterns, endoscopic findings, and gastric histology in Helicobacter pylori-infected and -uninfected patients.

    abstract::There is a paucity of data on the long-term behavior of dyspepsia, endoscopic findings, and gastroduodenal histology in patients with or without Helicobacter pylori colonization. We evaluated these parameters during a period of 7 to 19 years (average, 12.3 years) by baseline and follow-up studies. In 36 patients studi...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: DeLuca VA Jr,West AB,Haque S,Katz DL,Ciarolla D,Goldenberg S,Fette G

    更新日期:1998-03-01 00:00:00

  • Duodenal ulcer therapy with low-dose antacids: a multicenter trial.

    abstract::One hundred outpatients with endoscopically verified duodenal ulcer were treated in a double-blind, randomized, multicenter trial with either low-dose antacid (AA, Supralox, 1 tablet three times a day 1 h a.c. and 2 tablets at bedtime, with acid binding capacity of 225 mEq) or misoprostol (MS, Cytotec, 400 micrograms ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Nauert C,Caspary WF

    更新日期:1991-01-01 00:00:00

  • Oral Fecal Microbiota Transplant Capsules Are Safe and Effective for Recurrent Clostridioides difficile Infection: A Systematic Review and Meta-Analysis.

    abstract:GOALS:We performed a systematic review with meta-analysis to examine the efficacy and safety of oral fecal microbiota transplantation (FMT) capsules for recurrent Clostridioides difficile infection (rCDI). BACKGROUND:FMT through colonoscopy is established as effective and safe in treating multiple recurrences of CDI, ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Du C,Luo Y,Walsh S,Grinspan A

    更新日期:2021-01-19 00:00:00

  • Efficacy of sucralfate in the prevention of recurrence of duodenal ulcers.

    abstract::Eighty-four patients who were endoscopically confirmed to have healed duodenal ulcers were entered into this 1-year, double-blind, placebo-controlled trial of sucralfate, 1g twice daily, in the prevention of duodenal ulcer recurrence. Patients remained in the study until recurrence of ulceration was endoscopically con...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Behar J,Roufail W,Thomas E,Keller F,Dernbach W,Tesler MA

    更新日期:1987-01-01 00:00:00

  • Role of Gut Microbiota in Liver Disease.

    abstract::Many lines of research have established a relationship between the gut microbiome and patients with liver disease. For example, patients with cirrhosis have increased bacteremia, increased blood levels of lipopolysaccharide, and increased intestinal permeability. Patients with cirrhosis have bacterial overgrowth in th...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Brenner DA,Paik YH,Schnabl B

    更新日期:2015-11-01 00:00:00

  • Higher Thioguanine Nucleotide Metabolite Levels are Associated With Better Long-term Outcomes in Patients With Inflammatory Bowel Diseases.

    abstract:GOALS:The aim of this study was to assess whether sustained 6-thioguaninenucleotide (6-TGN) levels were associated with improved long-term outcomes in patients with inflammatory bowel diseases (IBD). BACKGROUND:Cross-sectional data have shown that thiopurine metabolites are correlated with clinical efficacy in patient...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Yarur AJ,Gondal B,Hirsch A,Christensen B,Cohen RD,Rubin DT

    更新日期:2018-07-01 00:00:00

  • Immunohistochemical study of sulfatide expression in gastric carcinoma: alteration of sulfatide expression.

    abstract::Immunohistochemical staining using a specific monoclonal antibody against sulfatide was performed to examine cellular localization of sulfatides in normal human gastric mucosa and in various types of gastric carcinoma. In normal gastric mucosa without Helicobacter pylori infection, both epithelial and glandular cells ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Osawa H,Sugano K,Igari T,Tai T,Iwamori M,Kawakami M

    更新日期:1997-01-01 00:00:00

  • Primary biliary cirrhosis and Graves' disease.

    abstract::We describe a patient with primary biliary cirrhosis associated with Graves' disease and discuss the possible autoimmune connections between the two disorders. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Nieri S,Riccardo GG,Salvadori G,Surrenti C

    更新日期:1985-10-01 00:00:00

  • Multiple esophageal webs: treatment and follow-up of seven patients.

    abstract::We have treated seven patients with multiple esophageal webs without a predisposing disorder. The patients ranged in age from 34 to 61 years and had suffered from dysphagia for 4 to 26 years. None had skin disease, a history of ingestion of a potentially caustic substance, or evidence of gastroesophageal reflux diseas...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Longstreth GF,Sitzer ME

    更新日期:1997-06-01 00:00:00

  • Fulminant acute Budd-Chiari syndrome stemming from an adrenal tumor.

    abstract::Adrenal neoplasm is a rare cause of Budd-Chiari syndrome. We report a case of fulminant acute Budd-Chiari syndrome due to inferior vena cava thrombosis stemming from invasion by a clinically nonfunctioning adrenal neoplasm. We also review briefly the clinical characteristics of the seven previously reported cases. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审


    authors: Moreira V,Aller R,De Luis DA,San Roman AL,Ferreiro A

    更新日期:1997-03-01 00:00:00

  • EUS-Directed Transgastric Endoscopic Retrograde Cholangiopancreatography (EDGE): The First Learning Curve.

    abstract:INTRODUCTION:Endoscopic ultrasound (EUS)-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE) is a minimally invasive option for pancreaticobiliary access in patients with Roux-en-Y anatomy. The procedure involves creating a fistulous tract between the remnant stomach or jejunum and the bypassed ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Tyberg A,Kedia P,Tawadros A,Tarnasky PR,Gaidhane M,Nieto J,Kahaleh M

    更新日期:2020-07-01 00:00:00

  • More Severe Deficits in Performance Status at Time of Liver Transplant is Associated With Significantly Higher Risk of Death Following Liver Transplantation.

    abstract:GOAL:To evaluate the impact of Karnofsky Performance Status score (KPSS) at the time of liver transplantation (LT) on post-LT survival. BACKGROUND:While the Model for End-Stage Liver Disease (MELD) score is used to prioritize individuals for LT, it does not specifically incorporate functional status into patient asses...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: McCabe P,Gish RG,Cheung R,Wong RJ

    更新日期:2019-10-01 00:00:00

  • Diagnostic yield of spiral enteroscopy when performed for the evaluation of abnormal capsule endoscopy findings.

    abstract:BACKGROUND:Spiral enteroscopy (SE) has emerged as a new alternative for deep intubation of the small intestine. SE is most often used to evaluate abnormal findings on capsule endoscopy (CE). OBJECTIVE:Investigate the ability of SE to reproduce abnormal findings detected on preceding CE. DESIGN:Prospective study. SET...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Buscaglia JM,Richards R,Wilkinson MN,Judah JR,Lam Y,Nagula S,Draganov PV

    更新日期:2011-04-01 00:00:00

  • Circulating interferon-like activity in inflammatory bowel disease.

    abstract::Inflammatory bowel diseases (IBD) has been characterized as having an autoimmune background. We studied the presence of immune interferon in the sera of a small number of patients with IBD. Antiviral activity was detectable in the sera of our patients with well-controlled IBD but it was mainly weak-positive (50% inhib...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Christodoulopoulou G,Havredaki M,Christodoulopoulos J

    更新日期:1986-10-01 00:00:00

  • Effects of probiotic Lactobacillus paracasei-enriched artichokes on constipated patients: a pilot study.

    abstract:GOALS:To determine whether the consumption of artichokes enriched with a probiotic Lactobacillus paracasei strain affects fecal microbiota composition, fecal enzyme activity, and short-chain fatty acids production and symptom profile in patients suffering from constipation. BACKGROUND:Constipation is a common gastroin...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章


    authors: Valerio F,Russo F,de Candia S,Riezzo G,Orlando A,Lonigro SL,Lavermicocca P

    更新日期:2010-09-01 00:00:00

  • Oral manifestations of Crohn's disease. An analysis of 79 cases.

    abstract::We report four new cases of oral manifestation in Crohn's disease (CD) and evaluate 75 reported cases for morphology and site of oral and intestinal manifestations of CD, clinical manifestation, and treatment. Oral CD was the presenting symptom in 43 of 72 (60%) patients and relapsed in 34 of 60 (57%). Median age at p...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审


    authors: Plauth M,Jenss H,Meyle J

    更新日期:1991-02-01 00:00:00

  • Mesenteric node enlargement as a cause of intestinal variceal hemorrhage in nodular lymphoid hyperplasia.

    abstract::Jejunal varices were a cause of recurrent gastrointestinal hemorrhage in an 18-year-old man with common variable immunodeficiency and nodular lymphoid hyperplasia of the small intestine. Despite numerous procedures, including upper gastrointestinal endoscopy, colonoscopy, arteriography, and exploratory laparotomy no a...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Freiman JS,Gallagher ND

    更新日期:1985-10-01 00:00:00

  • Digital Single-operator Cholangioscopy (DSOC) Improves Interobserver Agreement (IOA) and Accuracy for Evaluation of Indeterminate Biliary Strictures: The Monaco Classification.

    abstract:BACKGROUND:Visual characteristics seen during digital single-operator cholangioscopy (DSOC) have not been validated. The aim of this 2-phase study was to define terminology by consensus for the visual diagnosis of biliary lesions to develop a model for optimization of the diagnostic performance of DSOC. MATERIALS AND ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章


    authors: Sethi A,Tyberg A,Slivka A,Adler DG,Desai AP,Sejpal DV,Pleskow DK,Bertani H,Gan SI,Shah R,Arnelo U,Tarnasky PR,Banerjee S,Itoi T,Moon JH,Kim DC,Gaidhane M,Raijman I,Peterson BT,Gress FG,Kahaleh M

    更新日期:2020-02-07 00:00:00

  • Management of Chronic Hepatitis B in Pregnancy.

    abstract::Chronic hepatitis B virus (HBV) infection due to mother-to-child transmission during the perinatal period remains an important global health problem. Despite standard passive-active immunoprophylaxis with hepatitis B immunoglobulin and hepatitis B vaccine in neonates, up to 8.5% of newborns still acquire HBV infection...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审


    authors: Li J,Chang MS,Tran TT,Nguyen MH

    更新日期:2017-10-01 00:00:00