Is there a role for dietary essential fatty acids in gastroduodenal mucosal protection?

abstract：:A 35-year-old man developed leg edema, marked hypoalbuminemia, and proteinuria. Subsequent renal biopsy revealed a diffuse membranoproliferative glomerulonephritis and, on electron microscopy, typical electron-dense deposits characteristic of an immune complex pathogenesis. Although protein wasting might have readily ...

journal_title：Journal of clinical gastroenterology

authors： Scholey J,Freeman HJ

更新日期：1986-04-01 00:00:00

abstract：GOALS AND BACKGROUND:Nearly 40% of cytochrome P450 3A (CYP3A) activity is located in the small intestine. An earlier study has shown that cirrhotics with transjugular intrahepatic portosystemic shunts (TIPS) have diminished intestinal CYP3A activity. We hypothesized that oral CYP3A substrates known to prolong QT interv...

journal_title：Journal of clinical gastroenterology

authors： Vuppalanchi R,Juluri R,Ghabril M,Kim S,Thong N,Gorski JC,Chalasani N,Hall SD

更新日期：2011-08-01 00:00:00

abstract：:Portal hypertension, a consequence of end-stage liver disease and liver cirrhosis can lead to significant morbidity and mortality for patients through abnormal fluid accumulation as well as the formation of portosystemic shunts and varices. Treatment of the sequelae of portal hypertension can be achieved through endov...

journal_title：Journal of clinical gastroenterology

authors： Shreve L,Lee EW

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The prevalence of duodenal ulcer (DU) has been considered high in patients with chronic pancreatitis; however, its pathogenesis is unclear. We hypothesized that Helicobacter pylori infection plays the major pathogenetic role. STUDY:One hundred seven cases (97 men, 10 women) of chronic alcoholic pancreatitis...

journal_title：Journal of clinical gastroenterology

authors： Chebli JM,de Souza AF,Gaburri PD,Bastos KV,Ribeiro TC,Filho RJ,Chebli LA,Castro Ferreira LE

更新日期：2002-07-01 00:00:00

abstract：:Patients who are hepatitis B surface antigen (HBsAg) positive are at risk for hepatitis flare when receiving cytotoxic or immunosuppressive therapy. It has been reported that as high as 50% of HBsAg-positive individuals who undergo chemotherapy develop elevation of liver transaminases. According to current Association...

journal_title：Journal of clinical gastroenterology

authors： Wu JM,Huang YH,Lee PC,Lin HC,Lee SD

更新日期：2009-05-01 00:00:00

abstract：:A spontaneous intramural esophagogastric hematoma developed in a patient with hemophilia A. The hematoma did not resolve after antihemophiliac factor replacement but ruptured into the stomach causing massive gastrointestinal bleeding. The associated enlarged right tracheobronchial gland and the histopathological findi...

journal_title：Journal of clinical gastroenterology

authors： Intragumtornchai T,Israsena S,Benjacholamard V,Lerdlum S,Benjavongkulchai S

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Fatigue is common in inflammatory bowel disease (IBD) patients and is associated with factors such as psychopathology, sleep quality, and disease activity. GOAL:To investigate the combined role of all the above factors in the burden of fatigue among IBD patients. STUDY:We conducted an observational study o...

journal_title：Journal of clinical gastroenterology

authors： Hashash JG,Ramos-Rivers C,Youk A,Chiu WK,Duff K,Regueiro M,Binion DG,Koutroubakis I,Vachon A,Benhayon D,Dunn MA,Szigethy EM

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Human enteric antimicrobial peptides composed predominantly of human enteric α-defensins (HD5 and HD6) are important in the mucosal antimicrobial barrier. Previous studies have identified that genetic variations at rs2066844, rs2066845, rs2066847 are associated with diminished enteric α-defensins in...

journal_title：Journal of clinical gastroenterology

authors： Deng Q,Tan G,Deng F,Zhi F

更新日期：2020-07-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the intestine of unclear etiology. Increasing evidence has pointed to intestinal dysbiosis as a potential factor in a genetically susceptible individual. Fecal microbiota transplantation (FMT) has been used to treat inflammatory bowel disease with var...

journal_title：Journal of clinical gastroenterology

authors： Kao D,Hotte N,Gillevet P,Madsen K

更新日期：2014-08-01 00:00:00

abstract：:This review discusses gastrointestinal manifestations of parathyroid diseases. Parathyroid hormone is the primary regulator of calcium physiology. Hypoparathyroidism can be idiopathic, hereditary, or secondary to surgery in the neck. Hyperparathyroidism is usually from adenomas or hyperplasia. Hypoparathyroidism is as...

journal_title：Journal of clinical gastroenterology

authors： Ebert EC

更新日期：2010-08-01 00:00:00

abstract：:In this study we investigated the relationship between chronic gastric ulcers and the appearance of connexin 32 or connexin 43. Samples were taken endoscopically and the appearance of connexin 32 or connexin 43 was assessed by Western blotting using anticonnexin 32 or anticonnexin 43 antibodies. Normal gastric mucosa ...

journal_title：Journal of clinical gastroenterology

authors： Mine T,Yusuda H,Kataoka A,Tajima A,Nagasawa J,Takano T

更新日期：1995-01-01 00:00:00

abstract：:The response of plasma cyclic AMP to glucagon was investigated in 18 patients with acute liver injury to determine its value as a marker for the severity of the hepatic damage. We also investigated the interrelationship between plasma cyclic AMP response and the hyperglucagonemia often seen in this disease. Plasma cyc...

journal_title：Journal of clinical gastroenterology

authors： Miyakoshi H,Noda Y,Uchida S,Tanaka N,Noto Y,Kato Y,Kawai K,Hayakawa H,Kobayashi K,Hattori N

更新日期：1984-08-01 00:00:00

abstract：INTRODUCTION:Recently, an increasing interest to nonmotor symptoms of Parkinson disease (PD) has shown. Gastrointestinal dysfunction is a prominent nonmotor manifestation of PD and precedes motor symptoms for several years. Neuropathologic studies show early accumulation of α-synuclein (α-SYN) in Lewy neurites and Lewy...

journal_title：Journal of clinical gastroenterology

authors： Mrabet S,Ben Ali N,Achouri A,Dabbeche R,Najjar T,Haouet S,Belal S

更新日期：2016-10-01 00:00:00

abstract：:Adhesive tape wound around the shaft of an upper GI endoscope serves as a simple method to dilate upper GI strictures under endoscopic control. This technique avoids the need for guidewires and fluoroscopy. ...

journal_title：Journal of clinical gastroenterology

authors： Lehman GA,O'Connor KW

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Quantitative information is scarce with regard to guidelines for currently prescribed medications for constipation. Furthermore, these guidelines do not reflect the differences in the number of bowel movements caused by each drug. GOALS:In this study, we used a model-based meta-analysis to quantitatively es...

journal_title：Journal of clinical gastroenterology

authors： Zhang Y,Yin F,Xu L,Li YF,Chen JC,Liu HX,Zheng QS,Li LJ

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The occurrence of reflux disease seems to be rising in the United States. The aim of the present study was to follow the time trends of hospitalization for gastroesophageal reflux disease (GERD) and other esophageal disease during the past 4 decades. METHODS:US hospital utilization data were availa...

journal_title：Journal of clinical gastroenterology

authors： Sonnenberg A

更新日期：2014-09-01 00:00:00

abstract：:Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms comprising only 1% to 2% of all pancreatic tumors. In recent years, the number of incidentally discovered PNETs has greatly increased given the widespread use of axial imaging. However, a significant proportion of PNETs may not be visualized on con...

journal_title：Journal of clinical gastroenterology

authors： Rustagi T,Farrell JJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer (PC) is one of the leading causes of cancer death in Western countries. An increased risk for PC is known in a number of hereditary tumor syndromes. In selected individuals at high risk of developing PC, surveillance of the pancreas might be able to detect premalignant lesions and early inv...

journal_title：Journal of clinical gastroenterology

authors： Kluijt I,Cats A,Fockens P,Nio Y,Gouma DJ,Bruno MJ

更新日期：2009-10-01 00:00:00

abstract：:Various esophageal functional abnormalities have been described in patients with Barrett's esophagus (BE). A significantly higher esophageal acid exposure especially in the supine position has been documented in BE, as compared with the other gastroesophageal reflux disease phenotypes. In addition, weakly acidic reflu...

journal_title：Journal of clinical gastroenterology

authors： Fass R,Teramoto O,Kurin M,Khalessi A,Kitayama Y,Shibli F

更新日期：2020-07-01 00:00:00

abstract：:Athletes and bodybuilders often misuse androgenic/anabolic steroids. When used in therapeutic doses, these drugs produce clinical jaundice in just a small number of recipients. We present a 26-year-old male bodybuilder who self-administered high doses of androgenic/anabolic steroids that induced liver damage. One mont...

journal_title：Journal of clinical gastroenterology

authors： Stimac D,Milić S,Dintinjana RD,Kovac D,Ristić S

更新日期：2002-10-01 00:00:00

abstract：:Kidney stones in patients with inflammatory bowel disease are usually composed of calcium oxalate. Two factors are important in the increased absorption of dietary oxalate which is responsible for those stones: 1) increased absorption of oxalate in the presence of steatorrhea, and 2) increased permeability of the colo...

journal_title：Journal of clinical gastroenterology

authors： Dobbins JW

更新日期：1985-02-01 00:00:00

abstract：:A 36-year-old male patient, after 3 months' treatment with fluvastatin 40 mg/d for hypercholesterolemia, presented with acute pancreatitis. The pancreatitis was mild, and the patient settled on medical treatment. Other causes of the disease were ruled out. Some months later, the patient reintroduced fluvastatin on his...

journal_title：Journal of clinical gastroenterology

authors： Tysk C,Al-Eryani AY,Shawabkeh AA

更新日期：2002-11-01 00:00:00

abstract：:The clinical recognition of Helicobacter pylori gastritis in children with recurrent abdominal pain is difficult. We assessed the value of a simplified 13C urea breath test (13C-UBT) in a selected group of children with nocturnal waking and disruptive recurrent abdominal pain who fulfilled criteria for endoscopy. Gast...

journal_title：Journal of clinical gastroenterology

authors： Eltumi M,Brueton MJ,Francis N

更新日期：1999-04-01 00:00:00

abstract：:Intravenous erythromycin is a potent gastric prokinetic with demonstrated efficacy in the acute therapy of gastroparesis; long-term oral therapy has been limited by tolerance and modest efficacy. Our aim was to review our experience with prolonged administration of intravenous erythromycin in an ambulatory setting as ...

journal_title：Journal of clinical gastroenterology

authors： DiBaise JK,Quigley EM

更新日期：1999-03-01 00:00:00

abstract：:Image-guided percutaneous local and regional modalities are major treatments for hepatocellular carcinoma. Patients having better liver function and performance are usually eligible and can gain significant survival benefit, especially with more limited tumor burden. The most common local therapies are ethanol and rad...

journal_title：Journal of clinical gastroenterology

authors： Pollak JS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:There are few data regarding the prevalence of hepatitis-B virus (HBV) markers in inflammatory bowel disease (IBD) patients in Korea, which is a hepatitis-B-endemic area. The aim of this study was to assess the prevalence of HBV markers in IBD patients in comparison with controls. METHODS:We enrolled 513 IB...

journal_title：Journal of clinical gastroenterology

authors： Kim ES,Cho KB,Park KS,Jang BI,Kim KO,Jeon SW,Kim EY,Yang CH,Kim WJ,Daegugyeongbuk Gastrointestinal Study Group (DGSG).

更新日期：2014-07-01 00:00:00

abstract：:We compared eleven patients in whom symptoms of Crohn's disease appeared at age greater than or equal to 65 with a younger group in whom symptoms had appeared earlier. Only 64% of the older patients were initially recognized as having Crohn's disease, as compared with 96% of the younger patients even though clinical c...

journal_title：Journal of clinical gastroenterology

authors： Stalnikowicz R,Eliakim R,Diab R,Rachmilewitz D

更新日期：1989-08-01 00:00:00

abstract：:The esophagogastric junction (EGJ) is a complex barrier between the thoracic and abdominal luminal gut compartments, comprised primarily of the lower esophageal sphincter (LES) and crural diaphragm. Although closed at rest, the EGJ relaxes to allow antegrade bolus transit and retrograde venting of air. Abnormal relaxa...

journal_title：Journal of clinical gastroenterology

authors： Rogers BD,Gyawali CP

更新日期：2021-02-01 00:00:00

abstract：GOALS:To evaluate the effects of probucol, an agent with strong antioxidant properties, in reversing biochemical changes in nonalcoholic steatohepatitis (NASH). BACKGROUND:There is currently no well-established medical treatment of NASH. It is believed that oxidative stress plays a major role in hepatic damage in thes...

journal_title：Journal of clinical gastroenterology

authors： Merat S,Malekzadeh R,Sohrabi MR,Hormazdi M,Naserimoghadam S,Mikaeli J,Farahvash MJ,Ansari R,Sotoudehmanesh R,Khatibian M

更新日期：2003-03-01 00:00:00

abstract：:Forty-five polyps were encountered at duodenoscopy between 1973 and 1978. Upper gastrointestinal x-rays were helpful in 25 patients, 13 of whom had duodenal polyps and 12 duodenal deformity or mass lesions. Polyps in 23 patients were larger than 1 cm in size. Biopsies were done in 38 patients; in 19 there was only nor...

journal_title：Journal of clinical gastroenterology

authors： Reddy RR,Schuman BM,Priest RJ

更新日期：1981-06-01 00:00:00