Human chronic gastric ulcer and connexin.

abstract：:A great deal is known about methods to diminish intragastric acid concentration, but far less is known about the ability of the gastroduodenal mucosa to resist injury or accelerate its healing. One group of compounds that plays a key role in the endogenous ability of the mucosa to protect itself against injury and per...

journal_title：Journal of clinical gastroenterology

authors： Hollander D,Tarnawski A

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Although the efficacy of tacrolimus for inducing remission of refractory ulcerative colitis (UC) is established, its efficacy for maintaining remission of UC has not been evaluated. AIM:The aim of this study was to evaluate the efficacy of tacrolimus compared with thiopurines for maintaining remission in pa...

journal_title：Journal of clinical gastroenterology

authors： Yamamoto S,Nakase H,Matsuura M,Masuda S,Inui K,Chiba T

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Mortality from ST elevation myocardial infarction (STEMI) is decreasing nationwide, but no report to date examined STEMI mortality among patients with cirrhosis. GOALS:Determine mortality rates and investigate possible disparities in cardiovascular interventions for patients with and without cirrhosis admit...

journal_title：Journal of clinical gastroenterology

authors： Abougergi MS,Karagozian R,Grace ND,Saltzman JR,Qamar AA

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Visual characteristics seen during digital single-operator cholangioscopy (DSOC) have not been validated. The aim of this 2-phase study was to define terminology by consensus for the visual diagnosis of biliary lesions to develop a model for optimization of the diagnostic performance of DSOC. MATERIALS AND ...

journal_title：Journal of clinical gastroenterology

authors： Sethi A,Tyberg A,Slivka A,Adler DG,Desai AP,Sejpal DV,Pleskow DK,Bertani H,Gan SI,Shah R,Arnelo U,Tarnasky PR,Banerjee S,Itoi T,Moon JH,Kim DC,Gaidhane M,Raijman I,Peterson BT,Gress FG,Kahaleh M

更新日期：2020-02-07 00:00:00

abstract：:The bewildering array of medications in the therapy of inflammatory bowel disease (IBD) often confounds the clinician in the choice of specific agents regarding the balance between safety and efficacy. This review surveys and evaluates currently available IBD therapies as well as those used in clinical trials of ulcer...

journal_title：Journal of clinical gastroenterology

authors： Katz S

更新日期：2002-04-01 00:00:00

abstract：:A patient with long-standing Waldenström's disease and cryoglobulinemia, treated with chlorambucil, developed hepatocellular carcinoma. Although HBs antigen, anti-HBs, and anti-HBc antibodies were not detected in his serum by conventional polyclonal radioimmunoassays, immunofluorescence techniques showed HBs antigen t...

journal_title：Journal of clinical gastroenterology

authors： Lotz JP,Colbert N,Degott C,Pariente EA

更新日期：1985-10-01 00:00:00

abstract：:A 2-year-old boy presented with sexual precocity secondary to a hormone-producing hepatoblastoma. The tumor demonstrated an aggressive histologic pattern and stained immunohistochemically for alpha-fetoprotein and beta-subunit human chorionic gonadotrophin. After a successful liver transplant these tumor markers were ...

journal_title：Journal of clinical gastroenterology

authors： Heimann A,White PF,Riely CA,Ritchey AK,Flye MW,Barwick KW

更新日期：1987-02-01 00:00:00

abstract：:Crohn's disease can be accompanied by extraintestinal manifestations. The authors report on a 39-year-old patient who presented with cheilitis granulomatosa as the first manifestation of Crohn's disease. Four years later, intestinal Crohn's disease was diagnosed. One year afterward, acute loss of visual acuity from op...

journal_title：Journal of clinical gastroenterology

authors： van de Scheur MR,van der Waal RI,van Bodegraven AA,Völker-Dieben HJ,Starink TM,van der Waal I

更新日期：2002-05-01 00:00:00

abstract：:Increased amounts of small bowel gas are a frequent finding on plain abdominal films in toxic megacolon (TMC), but they may also be found in patients with severe colitis. We studied 69 consecutive patients with severe ulcerative colitis to evaluate whether an increased gas content of the small intestine may identify p...

journal_title：Journal of clinical gastroenterology

authors： Caprilli R,Vernia P,Latella G,Torsoli A

更新日期：1987-04-01 00:00:00

abstract：:In 23 patients with dermatitis herpetiformis (DH) and five patients with linear-IgA bullous dermatosis (BD), we evaluated the occurrence of histologic jejunal changes and small-bowel function abnormalities. None of the patients showed clinical signs or symptoms of malabsorption. Morphological jejunal changes consisten...

journal_title：Journal of clinical gastroenterology

authors： deFranchis R,Primignani M,Cipolla M,Vecchi M,Agape D,Monti M,Berti E,Zuccato E,Mussini E

更新日期：1983-10-01 00:00:00

abstract：:Infliximab is efficacious for refractory Crohn's disease, but delayed hypersensitivity reactions preclude retreatment for patients experiencing this complication. We report the results of four patients offered enrollment in an open label trial of thalidomide as "salvage" therapy for their refractory disease. Two patie...

journal_title：Journal of clinical gastroenterology

authors： Kane S,Stone LJ,Ehrenpreis E

更新日期：2002-08-01 00:00:00

abstract：:The esophagogastric junction (EGJ) is a complex barrier between the thoracic and abdominal luminal gut compartments, comprised primarily of the lower esophageal sphincter (LES) and crural diaphragm. Although closed at rest, the EGJ relaxes to allow antegrade bolus transit and retrograde venting of air. Abnormal relaxa...

journal_title：Journal of clinical gastroenterology

authors： Rogers BD,Gyawali CP

更新日期：2021-02-01 00:00:00

abstract：:Identical twins presented as sexagenarians with heartburn, regurgitation, and dysphagia; each had a Barrett esophagus remarkably similar to the other. This instance suggests a hereditary influence upon the development of mucosal dysplasia in some patients with this condition. ...

journal_title：Journal of clinical gastroenterology

authors： Gelfand MD

更新日期：1983-06-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) commonly affects women of childbearing age, leading to concerns about the effects of the disease on fertility and pregnancy, the effect of pregnancy on the disease, and the diagnosis and treatment of IBD in the pregnancy women. The literature regarding these issues is reviewed, and a r...

journal_title：Journal of clinical gastroenterology

authors： Vender RJ,Spiro HM

更新日期：1982-06-01 00:00:00

abstract：GOALS:We intended to identify the factors associated with missed appointments at a gastroenterology (GI) clinic in an academic setting. BACKGROUND:Missed clinic appointments reduce clinic efficiency, waste resources, and increase costs. Limited data exist on subspecialty clinic attendance. STUDY:We performed a case-c...

journal_title：Journal of clinical gastroenterology

authors： Shrestha MP,Hu C,Taleban S

更新日期：2017-05-01 00:00:00

abstract：:Radiation therapy directed at the abdomen may damage the digestive tract, the type and extent of injury depending on the dose of the radiation and the radiation sensitivity of the gut. Characteristic early changes are manifest in the mucosa of the gut: for later ulceration, changes in the collagen tissues and particul...

journal_title：Journal of clinical gastroenterology

authors： Novak JM,Collins JT,Donowitz M,Farman J,Sheahan DG,Spiro HM

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:Diagnosing a potentially life-threatening disease may adversely affect patient quality of life (QOL) independent of biologic effects. It is unknown whether the mere diagnosis of Barrett's esophagus (BE) adversely impacts patients' preferences (health-state utility) sufficiently to impair the cost-effectivene...

journal_title：Journal of clinical gastroenterology

authors： Rubenstein JH,Inadomi JM

更新日期：2006-02-01 00:00:00

abstract：:The goal of every routine endoscopy in the gut is the early diagnosis of malignant and premalignant changes of the mucosa. Chromo- and magnifying endoscopes are exciting new tools and offer detailed analysis of the colonic mucosal surface and pit pattern architecture. This review summarizes recent advances in endoscop...

journal_title：Journal of clinical gastroenterology

authors： Kiesslich R,Jung M,DiSario JA,Galle PR,Neurath MF

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The Maastricht 2-2000 guidelines on the current management of Helicobacter pylori infection were recently adopted by the Israeli Gastroenterological Association. GOAL:To determine the impact of these clinical guidelines on the current knowledge, attitudes, and management of H. pylori among primary care phys...

journal_title：Journal of clinical gastroenterology

authors： Shirin H,Birkenfeld S,Shevah O,Levine A,Epstein J,Boaz M,Niv Y,Avni Y

更新日期：2004-04-01 00:00:00

abstract：:Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu disease, is an hereditary disorder that results in fibrovascular dysplasia with the development of telangiectasias and arteriovenous malformations. It predominantly involves the skin, mucous membranes, viscera, lungs, and brain. Hereditary he...

journal_title：Journal of clinical gastroenterology

authors： Larson AM

更新日期：2003-02-01 00:00:00

abstract：:In 236 resection specimens of Crohn's disease (127 first excisions and 109 reexcisions) there were 60 specimens with fistulas (excluding anal fistulas): 44 in first excisions and 16 in reexcisions. In primary excisions, 36 fistulas arose in the ileum, three in the colon and five in the ileocecal valve. The majority we...

journal_title：Journal of clinical gastroenterology

authors： Kelly JK,Preshaw RM

更新日期：1989-04-01 00:00:00

abstract：:A fifty-year-old woman with abdominal pain, diarrhea, and weight loss ultimately required exploratory laparotomy. The entire small intestine was extensively infiltrated by poorly differentiated adenocarcinoma; mesenteric lymph nodes and surrounding omentum were involved, but no extragastrointestinal tumor was found. A...

journal_title：Journal of clinical gastroenterology

authors： Hansen RM,Lewis JD,Janjan NA,Komorowski RA

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Fatigue is common in inflammatory bowel disease (IBD) patients and is associated with factors such as psychopathology, sleep quality, and disease activity. GOAL:To investigate the combined role of all the above factors in the burden of fatigue among IBD patients. STUDY:We conducted an observational study o...

journal_title：Journal of clinical gastroenterology

authors： Hashash JG,Ramos-Rivers C,Youk A,Chiu WK,Duff K,Regueiro M,Binion DG,Koutroubakis I,Vachon A,Benhayon D,Dunn MA,Szigethy EM

更新日期：2018-05-01 00:00:00

abstract：:Endoscopy imaging of the gastrointestinal (GI) tract has evolved tremendously over the last few decades. Key milestones in the development of endoscopy imaging include the use of various dyes for chromoendoscopy, the application of optical magnification in endoscopy, the introduction of high-definition image capturing...

journal_title：Journal of clinical gastroenterology

authors： Ho SH,Uedo N,Aso A,Shimizu S,Saito Y,Yao K,Goh KL

更新日期：2018-04-01 00:00:00

abstract：GOALS:To estimate the hepatocellular carcinoma surveillance in the Medicaid cirrhotic population. BACKGROUND:Most studies predate 2005 American Association for the Study of Liver Diseases surveillance recommendations and do not examine the primary target population, cirrhotics. STUDY:From 2006 to 2007, we identified ...

journal_title：Journal of clinical gastroenterology

authors： Palmer LB,Kappelman MD,Sandler RS,Hayashi PH

更新日期：2013-09-01 00:00:00

abstract：:A 24-year-old man with addisonian pernicious anemia, adult celiac disease and selective IgA deficiency is presented to emphasize the differential diagnosis of vitamin B12 deficient megaloblastic anemia in association with small intestinal mucosal abnormalities and the relationships between immunoglobulin deficiency, p...

journal_title：Journal of clinical gastroenterology

authors： Quigley EM,Carmichael HA,Watkinson G

更新日期：1986-06-01 00:00:00

abstract：GOALS:To define both risks and costs of optimal care of patients with gastric acid hypersecretion. BACKGROUND:The management of Zollinger-Ellison syndrome and other gastric acid hypersecretory disorders remains challenging. The optimal strategy for follow-up including gastric acid analysis, laboratory studies, and end...

journal_title：Journal of clinical gastroenterology

authors： Hirschowitz BI,Fineberg N,Wilcox CM,Mohnen J,Worthington J

更新日期：2010-01-01 00:00:00

abstract：:Lower gastrointestinal bleeding colonic varices is infrequent. We report a patient in whom the diagnosis was made by angiography and in whom portosystemic shunt has been helpful. We believe that the treatment of choice for colonic varices is portosystemic shunt, as attempts at resection, judged by the reports in the l...

journal_title：Journal of clinical gastroenterology

authors： Katz LB,Shakeed A,Messer J

更新日期：1985-02-01 00:00:00

abstract：:We have studied the morphologic aspects of the duodenal bulb in relation to Helicobacter pylori infection in a large group of patients with endoscopically assessed duodenitis to learn more about the pathogenesis of nonspecific duodenitis (bulbitis) and to clarify the specific role of H. pylori. Eight duodenal biopsy s...

journal_title：Journal of clinical gastroenterology

authors： Caselli M,Gaudio M,Chiamenti CM,Trevisani L,Sartori S,Saragoni L,Boldrini P,Dentale A,Ruina M,Alvisi V

更新日期：1998-01-01 00:00:00

abstract：GOALS:To determine the long-term efficacy of endoluminal gastroplication (ELGP) and the most effective plication configuration. BACKGROUND:Endoluminal gastroplication is an intriguing therapy for gastroesophageal reflux disease. We conducted a retrospective review of a prospective experience of patient cohorts compari...

journal_title：Journal of clinical gastroenterology

authors： Davis RE,Iqbal A,Gerhardt JD,Welch RA,Turaga K,Tierney B,Haider M,Filipi CJ

更新日期：2005-11-01 00:00:00