A review of Silybum marianum (milk thistle) as a treatment for alcoholic liver disease.

abstract：:Gastroesophageal reflux disease, especially when refractory to standard therapy, remains a significant clinical problem. Although symptom pathogenesis in erosive reflux disease is relatively easy to understand, it is less clear how exposure of the macroscopically normal mucosa in nonerosive reflux disease (NERD) is ab...

journal_title：Journal of clinical gastroenterology

authors： Woodland P,Sifrim D

更新日期：2014-01-01 00:00:00

abstract：GOALS:The aim of this study was to compare celecoxib with loxoprofen for protection of small intestine. BACKGROUND:RCT studies report that COX-2 selective inhibitor celecoxib induces fewer small intestinal injuries than nonselective nonsteroidal anti-inflammatory drugs (NSAIDs). Loxoprofen is a prodrug nonselective NS...

journal_title：Journal of clinical gastroenterology

authors： Fujimori S,Hanada R,Hayashida M,Sakurai T,Ikushima I,Sakamoto C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Studies of serotonin reuptake transporter (SERT-P) polymorphism and irritable bowel syndrome (IBS) have shown diverse results among different populations, which might be due to racial and ethnic difference. AIM:This study was to investigate the potential association between the SERT-P polymorphism and clini...

journal_title：Journal of clinical gastroenterology

authors： Sikander A,Rana SV,Sinha SK,Prasad KK,Arora SK,Sharma SK,Singh K

更新日期：2009-11-01 00:00:00

abstract：:In up to 10% to 20% of colonoscopies, complete intubation of the colon may be considerably difficult. A principal cause of difficulty is looping of the endoscope shaft in a floppy, often tortuous segment of the colon that typically happens in the sigmoid colon. Also, if looping is not recognized and the scope is advan...

journal_title：Journal of clinical gastroenterology

authors： Hawari R,Pasricha PJ

更新日期：2007-02-01 00:00:00

abstract：:Celiac disease (CD) is the most common autoimmune enteropathy, triggered by a deregulated immune response to gliadin. It has been hypothesized that human intestinal microbiota may interfere with the pathogenesis of the disease and in the clinical course of CD. In the present review, we analyzed the microbiota alterati...

journal_title：Journal of clinical gastroenterology

authors： Losurdo G,Principi M,Iannone A,Ierardi E,Di Leo A

更新日期：2016-11-01 00:00:00

abstract：:To investigate the influence of the brain-gut interactions on the pathophysiology of irritable bowel syndrome (IBS), we compared such patients (n = 10) with healthy control subjects (n = 11) by measuring the pressure of the colon and small intestine simultaneously with analysis of power spectrum of the electroencephal...

journal_title：Journal of clinical gastroenterology

authors： Fukudo S,Nomura T,Muranaka M,Taguchi F

更新日期：1993-09-01 00:00:00

abstract：GOALS:Review of research directions in the etiology, evaluation, and treatment of patients with noncardiac chest pain. The author proposes a combined practical approach to noncardiac chest pain that incorporates these findings, which is useful in a clinical practice setting. BACKGROUND:Several major schools of thought...

journal_title：Journal of clinical gastroenterology

authors： Botoman VA

更新日期：2002-01-01 00:00:00

abstract：:During the past three decades, important advances in our understanding of the pathophysiology of chronic pancreatitis (CP), improved results of major pancreatic resections (including pancreatoduodenectomy), and integration of sophisticated diagnostic methods in clinical practice resulted in significant changes in our ...

journal_title：Journal of clinical gastroenterology

authors： Sakorafas GH,Tsiotou AG

更新日期：2002-01-01 00:00:00

abstract：:Occult gastrointestinal bleeding frequently frustrates clinicians' attempts to locate the source. Foci of hemorrhage within the small bowel are often found only at laparotomy and can be attributed to Meckel's diverticula, carcinomas, or less frequently, pulsion-type diverticula. We report our experience with two patie...

journal_title：Journal of clinical gastroenterology

authors： Rodriguez HE,Ziauddin MF,Quiros ED,Brown AM,Podbielski FJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Although of unproven benefit for nonalcoholic steatohepatitis (NASH), thiazolidinediones (TZDs) have emerged as a promising therapy. Little evidence exists, however, regarding sustained effects of TZDs in NASH after drug discontinuation. A recent clinical study suggests that relapse of NASH pathophysiology i...

journal_title：Journal of clinical gastroenterology

authors： Argo CK,Iezzoni JC,Al-Osaimi AM,Caldwell SH

更新日期：2009-07-01 00:00:00

abstract：:The ultrastructure of microvessels in the gastric mucosa of patients with atrophic gastritis was investigated. In the gastric mucosa of atrophic gastritis, the endothelial cells of microvessels were irregularly swollen and subendothelial spaces were enlarged. The basement membrane underlying the endothelium was thicke...

journal_title：Journal of clinical gastroenterology

authors： Taniguchi Y,Kimura K,Yoshida Y,Seki M,Kumakura Y,Satoh K,Kihira K,Ido K,Mato M

更新日期：1993-01-01 00:00:00

abstract：:Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, cannabinoid receptors 1 and 2, are found on cells of various tissues, with...

journal_title：Journal of clinical gastroenterology

authors： Unal E,Anderson B,Helber A,Marks JH

更新日期：2020-10-01 00:00:00

abstract：:We observed jejunal water and sodium secretion in two patients with chronic idiopathic intestinal pseudo-obstruction by standard perfusion techniques. The ability of glucose to reverse this secretory state was impaired. These observations suggest that a jejunal secretory state may contribute to the diarrhea in chronic...

journal_title：Journal of clinical gastroenterology

authors： Rolston DD,Hunt JB,Fairclough PD,Wilks M,Levison DA,Clark ML,Farthing MJ

更新日期：1990-04-01 00:00:00

abstract：:Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms comprising only 1% to 2% of all pancreatic tumors. In recent years, the number of incidentally discovered PNETs has greatly increased given the widespread use of axial imaging. However, a significant proportion of PNETs may not be visualized on con...

journal_title：Journal of clinical gastroenterology

authors： Rustagi T,Farrell JJ

更新日期：2014-11-01 00:00:00

abstract：GOALS:To determine the proportion of patients with gastroesophageal reflux disease who are on proton pump inhibitors (PPIs) who could reduce their prior dosage by half, and identify predictors of successful step-down. BACKGROUND:Appropriate hypergastrinemia results from gastric acid inhibition. A gender difference in ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Metz DC,Lund SH,Gizurarson S,Jacobsen EI,Asgeirsdóttir GA,Yngadóttir Y,Björnsson ES

更新日期：2017-07-01 00:00:00

abstract：:Two cases of multiple lymphomatous polyposis (MLP) are presented, involving different segments of the gastrointestinal tract. Both cases display the characteristic clinical and pathologic features of MLP. In addition, we were able to document, for the first time, the endoscopic ultrasonographic findings in this diseas...

journal_title：Journal of clinical gastroenterology

authors： Viana HL,Henrique RM,Ferreira ES,Correia AM,Silva RA,Dias LM,Viana RL

更新日期：2002-02-01 00:00:00

abstract：:We have treated seven patients with multiple esophageal webs without a predisposing disorder. The patients ranged in age from 34 to 61 years and had suffered from dysphagia for 4 to 26 years. None had skin disease, a history of ingestion of a potentially caustic substance, or evidence of gastroesophageal reflux diseas...

journal_title：Journal of clinical gastroenterology

authors： Longstreth GF,Sitzer ME

更新日期：1997-06-01 00:00:00

abstract：:This article emphasizes and reviews the premise that because the pathogenesis of acute gastric mucosal injury is multifactorial, several protective mechanisms should also be considered in analyzing gastric mucosal defense. The first part of the article reviews the pathogenesis of acute gastric mucosal injury by major ...

journal_title：Journal of clinical gastroenterology

authors： Szabo S

更新日期：1991-01-01 00:00:00

abstract：:The tissue distribution of a previously identified M(r) 40 K epithelial autoantigen in ulcerative colitis was examined in situ in the fetal tissue by immunocytochemical method, using an immunoglobulin M (IgM) monoclonal antibody (7E12H12). Fetal-autopsy tissue from 9 to 19 weeks of development (11-21 gestational weeks...

journal_title：Journal of clinical gastroenterology

authors： Das KM,Squillante L,Chitayet D,Kalousek DK

更新日期：1992-12-01 00:00:00

abstract：GOALS:To compare the healthcare resource consumption of patients who have irritable bowel syndrome (IBS) with an age-, gender-, and comorbidity-matched cohort of patients without IBS from a managed care perspective. STUDY:Retrospective cohort analysis. Data were obtained electronically through the Henry Ford Health Sy...

journal_title：Journal of clinical gastroenterology

authors： Patel RP,Petitta A,Fogel R,Peterson E,Zarowitz BJ

更新日期：2002-07-01 00:00:00

abstract：:Helicobacter pylori infection may play a role in the development of gastric cancer; however, a quantitative evaluation of the density of H. pylori infection has not been reported previously in relation to the histologic stage and type of cancer. This study was designed to compare the density of H. pylori infection to ...

journal_title：Journal of clinical gastroenterology

authors： Tokunaga Y,Shirahase H,Hoppou T,Kitaoka A,Tokuka A,Ohsumi K

更新日期：2000-10-01 00:00:00

abstract：:The intensity of diagnostic workup of patients with human immunodeficiency virus (HIV)-related chronic diarrhea is controversial. In the ideal setting in which an enteric pathogen is detected with minimal evaluation (stool tests) and in which specific treatment clears the diarrhea, eradicates the pathogen, and improve...

journal_title：Journal of clinical gastroenterology

authors： Rabeneck L

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:JC virus (JCV) is thought to infect approximately 80% of the human population. Antibodies against JCV can be found in the sera of many people with and without colorectal carcinoma (CRC). We hypothesized that JCV antibody titer will be higher in CRC patients than in healthy controls. AIM:To evaluate this hypo...

journal_title：Journal of clinical gastroenterology

authors： Niv Y,Vilkin A,Levi Z

更新日期：2010-08-01 00:00:00

abstract：:We report the development of ulcerative colitis (UC) and Crohn's disease (CD) Health Status Scales that improve on existing inflammatory bowel disease (IBD) activity measures by their added association with health status. We surveyed 991 members of the Crohn's and Colitis Foundation of America (CCFA) and analyzed the ...

journal_title：Journal of clinical gastroenterology

authors： Drossman DA,Li Z,Leserman J,Patrick DL

更新日期：1992-09-01 00:00:00

abstract：INTRODUCTION:Recently, an increasing interest to nonmotor symptoms of Parkinson disease (PD) has shown. Gastrointestinal dysfunction is a prominent nonmotor manifestation of PD and precedes motor symptoms for several years. Neuropathologic studies show early accumulation of α-synuclein (α-SYN) in Lewy neurites and Lewy...

journal_title：Journal of clinical gastroenterology

authors： Mrabet S,Ben Ali N,Achouri A,Dabbeche R,Najjar T,Haouet S,Belal S

更新日期：2016-10-01 00:00:00

abstract：:Helicobacter pylori is absent in the antrum of approximately 5, 25, and 35% of patients with duodenal ulcer, gastric ulcer, and non-ulcer dyspepsia respectively and in the majority of asymptomatic healthy subjects from the West. The absence of H. pylori from the antrum could result from failure of exposure to (Group A...

journal_title：Journal of clinical gastroenterology

authors： Desai HG,Gill HH

更新日期：1991-10-01 00:00:00

abstract：:In advanced cirrhosis and hepatorenal syndrome, peripheral vasodilation is a prominent feature and may be pathophysiologically relevant. To determine whether the potent vasodilator, calcitonin gene-related peptide (CGRP), circulates at abnormal levels in patients with these disorders, we observed eight patients with a...

journal_title：Journal of clinical gastroenterology

authors： Gupta S,Morgan TR,Gordan GS

更新日期：1992-03-01 00:00:00

abstract：GOALS:The goal of this study was to elucidate the most important predictors for elevation of gastrin in patients on long-term PPI therapy through analysis of data from 2 published studies in Icelandic patients with erosive GERD. BACKGROUND:Gastrin elevation is a known but variable consequence of proton pump inhibitor ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Lund SH,Gizurarson S,Metz DC,Björnsson ES

更新日期：2020-03-01 00:00:00

abstract：:Disposable biopsy forceps have recently been introduced into the field of endoscopy. We have analyzed biopsy size and histologic interpretation of samples obtained with the disposable forceps and compared them to those obtained with reusable forceps. In the 18 patients studied, 49 samples were collected with the reusa...

journal_title：Journal of clinical gastroenterology

authors： Turk DJ,Kozarek RA,Botoman VA,Patterson DJ,Ball TJ

更新日期：1991-02-01 00:00:00

abstract：:Enterovesical fistula associated with lymphoma is exceedingly rare. We report three patients with the acquired immunodeficiency syndrome who presented with fecaluria and pneumaturia. Non-Hodgkin lymphomas involving the intestine and the urinary bladder creating an enterovesical fistula were found at surgery in two pat...

journal_title：Journal of clinical gastroenterology

authors： Genta RM,Ramchandani MK,Gyorkey F,Buzanis CT,Lahart CJ

更新日期：1993-06-01 00:00:00