Abstract:
:Polychlorinated biphenyls (PCBs) are pervasive environmental contaminants that can have damaging effects on physiologic, motoric and cognitive function. Results from studies on PCBs and behavior have shown that exposure can alter learning and memory processes and that these shifts in cognitive abilities can be related to changes in hormonal and neural function. Little experimentation has been done on the impact of exposure to PCBs on social and emotional development. Previous work has shown that exposure to PCBs in children can alter play behavior. Importantly, exposure to PCBs has been found to change aspects of maternal-offspring interactions in rodents. The present study examined the impact of PCBs on maternal odor conditioning in rat pups 12-14 days of age. A modified version of the conditioned place preference paradigm was used that incorporated a maternal-associated odor cue (lemon scent) as the conditioned stimulus. PCBs significantly depressed the preference for the maternal-associated cue but did not impair discrimination for a novel odor. These effects could arise due to changes in the social dynamics between the dam and offspring after co-exposure to PCBs. For example, dams exposed to PCBs during gestation have been found to show elevated grooming directed towards pups exposed to PCBs. This change in maternal care can have dramatic effects on behavioral and hormonal systems in the developing rat pup. In conclusion, perinatal PCBs alter important social behaviors of both the mother and pup, and these alterations could have long-lasting effects on behavioral, cognitive and emotional development.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Cromwell HC,Johnson A,McKnight L,Horinek M,Asbrock C,Burt S,Jolous-Jamshidi B,Meserve LAdoi
10.1016/j.physbeh.2007.03.029subject
Has Abstractpub_date
2007-08-15 00:00:00pages
658-66issue
5eissn
0031-9384issn
1873-507Xpii
S0031-9384(07)00122-9journal_volume
91pub_type
杂志文章abstract::Vasopressin has been reported to be an endogenous antipyretic peptide. The present study assessed whether this peptide has similar effects on stress-induced hyperthermia. Infusion of 3 ng of vasopressin into the lateral ventricle prior to a 40-min restraint stress reduced significantly the hyperthermic response of rat...
journal_title:Physiology & behavior
pub_type: 杂志文章
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abstract::Rats with a history of severe early malnutrition (6% casein) were compared to well-fed control animals on an ascending series of DRL values ranging from 5 to 60 seconds. The 6% rats who were dietarily-rehabilitated at weaning did not differ from control animals in efficiency, responses per reinforcement or response ra...
journal_title:Physiology & behavior
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doi:10.1016/0031-9384(86)90271-4
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90076-0
更新日期:1994-05-01 00:00:00
abstract::The effects of denervation of fungiform taste buds on preference behavior were studied. Presurgery, 0.01, 0.1, 0.2, and 0.4 M NaCl, and 0.1, 0.2, and 0.4 M KCl were strongly avoided relative to water as measured with 48-h intakes. Bilateral cuts of the chorda tympani nerve (CT) resulted in a decrease in the strength o...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::The present study was carried out to determine possible panicogenic effects of strychnine administered in subconvulsive doses to rats. Two experiments were conducted to assess two major features of panic in animal models: panic-related flight (through the observation of wild running [WR]) and defensive fights. In the ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2003.10.003
更新日期:2004-01-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90198-4
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(79)90122-7
更新日期:1979-07-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.02.042
更新日期:2019-05-15 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.112734
更新日期:2020-02-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2008.04.018
更新日期:2008-08-06 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)02108-6
更新日期:1996-02-01 00:00:00
abstract::Sleep/wake expression in mice varies predictably with circadian phase. Such circadian rhythms are known to depend on intact suprachiasmatic nuclei (SCN) in the hypothalamus, but the mechanism by which SCN activity modulates sleep/wake expression is unknown. This paper examines the possibility that circadian patterns o...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90375-7
更新日期:1988-01-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.113035
更新日期:2020-10-01 00:00:00
abstract::The pancreatic B-cell hormone amylin has been proposed to be both a satiation signal and an adiposity signal. The effects of peripheral amylin on energy balance are well investigated, but the effects of central amylin are less clear. We determined the effects of low doses of amylin administered into the 3rd cerebral v...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.04.012
更新日期:2010-08-04 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90438-t
更新日期:1991-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90373-a
更新日期:1992-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90482-h
更新日期:1992-12-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2012.04.014
更新日期:2012-08-20 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90269-5
更新日期:1984-03-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90073-3
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abstract::Glucocorticoids have major effects on food intake, however, the underlying mechanisms are poorly understood. This article highlights data on the changes that occur when glucocorticoids are removed by adrenalectomy, and the effects of central and systemic administered glucocorticoids on feeding behavior in rats. Next, ...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2006.01.028
更新日期:2006-08-30 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90374-b
更新日期:1992-11-01 00:00:00
abstract::One group of male rats was reared continuously in small, stable colonies of three animals each during a ten-week period beginning when they were 46 days old. A second group of animals was also reared in small groups of three animals each but membership within these colonies was randomly changed at weekly intervals. Th...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90373-1
更新日期:1984-10-01 00:00:00
abstract::Eating rate has recently been shown to influence energy intake and appetite during an ad libitum meal, and alter postprandial secretion of glucagon-like peptide-1 (GLP-1) and peptide-YY (PYY) following a fixed-portion meal. Whether these effects influence satiety, as measured by energy intake at the subsequent meal, i...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2011.01.007
更新日期:2011-03-28 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90012-9
更新日期:1982-08-01 00:00:00
abstract::Spinal cord injury (SCI) is often accompanied by additional tissue damage (polytrauma) that provides a source of pain input. Our studies suggest that this pain input may be detrimental to long-term recovery. In a rodent model, we have shown that engaging pain (nociceptive) fibers caudal to a lower thoracic contusion S...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.112695
更新日期:2019-12-01 00:00:00
abstract::Rats shifted from a 32% to 4% sucrose solution consume substantially less 4% sucrose than unshifted animals that experience only the 4% solution. This negative contrast effect was found to be attenuated by lesions of the lateral aspects of the amygdala (basolateral, lateral, and basomedial nuclei) and eliminated by le...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90035-0
更新日期:1984-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(75)90078-5
更新日期:1975-06-01 00:00:00
abstract::Today, there are still uncertainties about the role of exogenous fat on body fat regulation. Early models of energy utilization (for example, Kleiber's, early 20th century) failed to take into account the nature of substrate oxidized in the control of food intake, whereas more recent models (e.g., Flatt's model, end o...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2004.09.015
更新日期:2004-12-30 00:00:00
abstract::Whether spontaneous food intake (SFI) is controlled by infused nutrient type or its caloric content, irrespective of nutrient type, was investigated. Rats were infused for 4 days with isocaloric solutions of different nutrient type but sharing the same intermediary metabolic oxidative pathway, providing 25% of daily c...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)00028-h
更新日期:1995-07-01 00:00:00