Abstract:
:Obesity has reached near epidemic proportions in the developed world. As reproductive age women are a part of this trend, the effect of maternal obesity on the developing fetus must be investigated. In this review, we evaluated the experimental evidence relating maternal nutritional status and eating behavior before and during pregnancy on the risk of obesity in the offspring. The studies were compiled and selected based on their methodologies, study design and relevance. The analyzed studies were compiled to quantify, if possible, the relationship between maternal and offspring weight. Descriptive and observational studies were also included if they were seminal in the field. Based on the current data, maternal obesity is a critical factor exacerbating multigenerational obesity. Mechanistic studies, mainly in animals, have identified potential areas for intervention which might limit transmission of adverse risk factors for obesity from mothers to infants during pregnancy.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Sen S,Carpenter AH,Hochstadt J,Huddleston JY,Kustanovich V,Reynolds AA,Roberts Sdoi
10.1016/j.physbeh.2012.04.014subject
Has Abstractpub_date
2012-08-20 00:00:00pages
138-45issue
1eissn
0031-9384issn
1873-507Xpii
S0031-9384(12)00163-1journal_volume
107pub_type
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