Chronic stress exposure may affect the brain's response to high calorie food cues and predispose to obesogenic eating habits.

Abstract:

:Exaggerated reactivity to food cues involving calorically-dense foods may significantly contribute to food consumption beyond caloric need. Chronic stress, which can induce palatable "comfort" food consumption, may trigger or reinforce neural pathways leading to stronger reactions to highly rewarding foods. We implemented functional magnetic resonance imaging (fMRI) to assess whether chronic stress influences activation in reward, motivation and executive brain regions in response to pictures of high calorie and low calorie foods in thirty women. On separate lab visits, we also assessed food intake from a snack food buffet and circulating cortisol. In women reporting higher chronic stress (HCS), pictures of high calorie foods elicited exaggerated activity in regions of the brain involving reward, motivation, and habitual decision-making. In response to pictures of high calorie food, higher chronic stress was also associated with significant deactivation in frontal regions (BA10; BA46) linked to strategic planning and emotional control. In functional connectivity analysis, HCS strengthened connectivity between amygdala and the putamen, while LCS enhanced connectivity between amygdala and the anterior cingulate and anterior prefrontal cortex (BA10). A hypocortisolemic signature and more consumption of high calorie foods from the snack buffet were observed in the HCS group. These results suggest that persistent stress exposure may alter the brain's response to food in ways that predispose individuals to poor eating habits which, if sustained, may increase risk for obesity.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Tryon MS,Carter CS,Decant R,Laugero KD

doi

10.1016/j.physbeh.2013.08.010

subject

Has Abstract

pub_date

2013-08-15 00:00:00

pages

233-42

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(13)00258-8

journal_volume

120

pub_type

杂志文章
  • "The addition of naltrexone alters cerebral glucose uptake following acute forced swimming".

    abstract::Endogenous opioid release has been linked to exercise. We investigated if opioid blockade following forced swimming, a common model of rodent exercise, influenced cerebral glucose metabolism in mice. PET scan was used to assess the uptake of Fludeoxyglucose (FDG-18), a marker of cerebral glucose metabolism in 19 regio...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.113199

    authors: Qadiri Q,York H,Muth BJ,Longoria CR,Campbell SC,Guers JJ

    更新日期:2021-01-01 00:00:00

  • Repeated stressor exposure enhances contextual fear memory in a beta-adrenergic receptor-dependent process and increases impulsivity in a non-beta receptor-dependent fashion.

    abstract::Memory formation is promoted by stress via the release of norepinephrine and stimulation of beta-adrenergic receptors (β-ARs). Previous data demonstrate that repeated stressor exposure increases norepinephrine turnover and β-AR signaling within the amygdala, which led to the hypothesis that some stress-induced behavio...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.03.008

    authors: Camp RM,Johnson JD

    更新日期:2015-10-15 00:00:00

  • Drop-out, relapse and abstinence in a cohort of alcoholic people under detoxification.

    abstract::The Obsessive Compulsive Drinking Scale (OCDS) was developed to reflect obsessionality and compulsivity related to craving and drinking behaviour for revealing in the long-term drop-out, abstinence and relapse. This study evaluates the early OCDS predictive value in drop-out, abstinence and relapse of patients sufferi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2018.10.009

    authors: Ledda R,Battagliese G,Attilia F,Rotondo C,Pisciotta F,Gencarelli S,Greco A,Fiore M,Ceccanti M,Attilia ML

    更新日期:2019-01-01 00:00:00

  • Infantile (handling) stimulation and behavior in young Roman high- and low-avoidance rats.

    abstract::The effect of infantile handling stimulation on exploratory and emotional behavior of Roman high- and low-avoidance (RHA/Verh and RLA/Verh) weanling rats was investigated. Postnatally handled and nonhandled, 4-week-old males and females from both psychogenetically selected lines were exposed to a hexagonal tunnel maze...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90546-z

    authors: Fernández-Teruel A,Escorihuela RM,Driscoll P,Tobeña A,Bättig K

    更新日期:1991-09-01 00:00:00

  • Relative hedonic value modulates anticipatory contrast.

    abstract::Intake of an initial substance (e.g., 0.15% saccharin) is suppressed when the presentation of this substance precedes the availability of a preferred solution (e.g., 32% sucrose) in brief daily pairings. The present experiments show that degree of this anticipatory contrast effect is related to the relative hedonic va...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90386-7

    authors: Flaherty CF,Turovsky J,Krauss KL

    更新日期:1994-06-01 00:00:00

  • An analysis of the role of stimulus removal in taste adaptation by means of simulated drinking.

    abstract::Human multiple sip drinking was simulated by repeated, alternate application of a NaCl solution and a second liquid to the anterior portion of the tongue. Judged intensity of the NaCl solution remained constant during alternation with artificial saliva, increased during alternation with water, and decreased during alt...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90454-3

    authors: Halpern BP,Kelling ST,Meiselman HL

    更新日期:1986-01-01 00:00:00

  • Differential effects of lipopolysaccharide in the social behavior of dominant and submissive mice.

    abstract::Acutely infected animals show a set of non-specific behavioral changes known as sickness behavior. Recent studies have shown that occurrence of sickness behavior is regulated according to a motivational perspective. Thus, the display of sickness behavior may compete with display of other behaviors. In this work, we so...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2006.02.011

    authors: Cohn DW,de Sá-Rocha LC

    更新日期:2006-05-30 00:00:00

  • Spatial memory under acute cold and restraint stress.

    abstract::This study examined spatial memory as measured by radial arm maze (RAM) performance after exposure to two stress conditions and a normothermic-unrestrained control condition. Male Fischer 344 rats were trained on the win-shift RAM procedure for 7 days, by which time they achieved asymptotic performance. The next day, ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(98)00091-2

    authors: Stillman MJ,Shukitt-Hale B,Levy A,Lieberman HR

    更新日期:1998-07-01 00:00:00

  • Cholinergic and GABAergic modulation of self-stimulation of lateral hypothalamus and ventral tegmentum: effects of carbachol, atropine, bicuculline, and picrotoxin.

    abstract::This study aimed at investigating the effects of modulators of acetylcholine-muscarinic (ACh-M) and GABAA.B-receptors in the lateral hypothalamus and ventral tegmentum on the electrical self-stimulation evoked from these regions. In each Wistar rat, a bipolar electrode and an ipsilateral insulated cannula-cum-electrod...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00452-0

    authors: Singh J,Desiraju T,Raju TR

    更新日期:1997-03-01 00:00:00

  • Plasma levels of dihydrotestosterone in the cycling rat: implications for the regulation of lordosis behavior.

    abstract::Exogenously administered dihydrotestosterone (DHT) is a potent inhibitor of sexual behavior in ovariectomized, estrogen-primed rats and endogenous DHT has been implicated as an inhibitor of sexual behavior in cycling rats. To determine the temporal relationship between DHT levels and the expression of sexual behavior,...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(88)90298-3

    authors: Dunlap KD,Sridaran R

    更新日期:1988-01-01 00:00:00

  • Caudate nucleus lesion selectively increases paradoxical sleep episodes in the rat.

    abstract::The EMG, ECG and the behavioral activity of seven rats were recorded for three days previous to and 24 hours after lesioning both caudate-putamen complexes. Following the lesion, the paradoxical sleep stage lengthened by about 248%, without noticeable changes in the slow wave sleep or in the waking stages. The greates...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(75)90133-x

    authors: Corsi-Cabrera M,Grinberg-Zylberbaum J,Arditti LS

    更新日期:1975-01-01 00:00:00

  • Effect of load carriage and natural terrain conditions on cognitive performance in desert environments.

    abstract:BACKGROUND:Correct decision making is a critical component of cognitive performance of a soldier, which may be influenced by the load carriage and terrain conditions during their deployment in desert environment. PURPOSE:The present study was aimed to investigate the effects of loads and terrain conditions on the cogn...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.06.014

    authors: Bhattacharyya D,Pal M,Chatterjee T,Majumdar D

    更新日期:2017-10-01 00:00:00

  • Predictive behaviors for anxiety and depression in female Wistar rats subjected to cafeteria diet and stress.

    abstract::Obesity and chronic stress have been considered important public health problems that affect millions of people worldwide. Our aim was to analyze the effect of obesity associated with chronic stress on neurobehavioral parameters in female rats, considering that the association of these syndromes can enhance the negati...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.07.016

    authors: da Costa Estrela D,da Silva WA,Guimarães AT,de Oliveira Mendes B,da Silva Castro AL,da Silva Torres IL,Malafaia G

    更新日期:2015-11-01 00:00:00

  • Physical activity induced protection against breast cancer risk associated with delayed parity.

    abstract::Epidemiological evidence indicates that physical activity between menarche and first pregnancy is associated with a lower risk of breast cancer among women with at least 20years between these reproductive events. The mechanism by which physical activity during this interval confers protection is unknown. This study us...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2016.11.026

    authors: Sturgeon KM,Schweitzer A,Leonard JJ,Tobias DK,Liu Y,Cespedes Feliciano E,Malik VS,Joshi A,Rosner B,De Jonghe BC

    更新日期:2017-02-01 00:00:00

  • Malaise can condition avoidance of high-viscosity fluids.

    abstract::Previous researchers have assumed that malaise-inducing drugs condition aversions to tastes more readily than to textural stimuli. The present report shows that rats given a single injection of lithium chloride after they have sampled a viscous fluid, subsequently showed greater avoidance of that fluid than did contro...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90373-a

    authors: Ramirez I

    更新日期:1992-11-01 00:00:00

  • Properties of smooth pursuit adaptation induced by theta motion.

    abstract::Current study attempted to determine whether repeated smooth pursuit trials using theta motion, in which the directions of retinal image-motion and object-motion are opposed, yield pursuit adaptation. Adaptation trials consisted of 350 step-ramp trials using theta motion, and pre- and post-trials using first-order mot...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.113245

    authors: Miyamoto T,Miura K,Kizuka T,Ono S

    更新日期:2021-02-01 00:00:00

  • Peripherally administered CRH suppresses the vocalizations of isolated guinea pig pups.

    abstract::In Experiment 1, an SC injection of 14 micrograms CRH greatly suppressed the vocalizing of isolated guinea pig pups 1 h later and produced highly elevated plasma cortisol levels. In Experiment 2, SC injection of 18 international units of ACTH produced similar cortisol elevations, but had a negligible effect on vocaliz...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90492-7

    authors: Hennessy MB,Becker LA,O'Neil DR

    更新日期:1991-07-01 00:00:00

  • The effects of caffeine on memory for word lists.

    abstract::The present study investigated the effects of caffeine on memory for supraspan word lists. Twelve groups of male and female college students classified as high or low impulsive were administered (PO) 0 mg/kg, 2 mg/kg or 4 mg/kg of caffeine. Subjects listened to four word lists presented at a fast rate and four at a sl...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90170-2

    authors: Erikson GC,Hager LB,Houseworth C,Dungan J,Petros T,Beckwith BE

    更新日期:1985-07-01 00:00:00

  • In quest for a possible association between heightened social aggression and excessive alcohol drinking in the rat.

    abstract::Many clinical studies show that a sizeable proportion of male alcoholics are also inclined to act violently and aggressively. Given this association in humans, we asked whether a relationship exists between ethanol intake and aggressive behaviour in laboratory rats. In a first test of the hypothesis, we measured ethan...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)02156-6

    authors: Bergvall AH,Fahlke C,Jönsson L,Hansen S

    更新日期:1996-04-01 00:00:00

  • Intracerebroventricular (i.c.v.) administration of mouse leptin in rats: behavioral specificity and effects on meal patterns.

    abstract::Leptin is a protein that is produced primarily in fat tissue and is thought to be a lipostatic feedback signal for the regulation of body fat stores. The purpose of this study was to determine the behavioral specificity of i.c.v.-administered mouse leptin in rats and to assess the effects on meal patterns. Using a mod...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(98)00180-2

    authors: Hulsey MG,Lu H,Wang T,Martin RJ,Baile CA

    更新日期:1998-12-01 00:00:00

  • Amylin decreases meal size in rats.

    abstract::Adult male rats were intraperitoneally (i.p.) injected with 1.0 microgram/kg amylin at the beginning of the dark phase in 24 h food deprived or undeprived rats, and a computerized system measured feeding behavior. In food deprived rats, amylin reduced the size of the first postdeprivation meal without affecting intram...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)02067-5

    authors: Lutz TA,Geary N,Szabady MM,Del Prete E,Scharrer E

    更新日期:1995-12-01 00:00:00

  • Capsaicin and its effects upon meal patterns, and glucagon and epinephrine suppression of food intake.

    abstract::The neurotoxin capsaicin has been shown to selectively interfere with unmyelinated sensory fibers, as well as leading to depletions of substance P and other peptides. Meal pattern analysis was performed both before and after treatment with capsaicin in twelve adult male Sprague-Dawley rats. Capsaicin treatment only br...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90056-4

    authors: Castonguay TW,Bellinger LL

    更新日期:1987-01-01 00:00:00

  • Water maze performance and changes in serum corticosterone levels in zinc-deprived and pair-fed rats.

    abstract::The aims of the present study were (1) to evaluate the learning and short- and long-term memory of zinc-deprived (ZD) and pair-fed (PF) rats in a Morris water maze (MWM) and (2) to monitor the serum corticosterone levels of these rats before and after swimming. Young Sprague-Dawley rats (aged 27-31 days) consumed AIN-...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(03)00041-6

    authors: Chu Y,Mouat MF,Harris RB,Coffield JA,Grider A

    更新日期:2003-04-01 00:00:00

  • A mouse model of alcoholism.

    abstract::A model of alcoholism should demonstrate self-administration of alcohol by the animal and a withdrawal syndrome when the animal no longer has access to the drug. A mouse model is described that meets these criteria and enables the induction of "alcoholism" in a large number of animals within a short period of time. Mi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90333-x

    authors: Rijk H,Crabbe JC,Rigter H

    更新日期:1982-11-01 00:00:00

  • Ambulatory activity in streptozotocin-induced diabetic rats.

    abstract::This study was undertaken to investigate changes in ambulatory and drinking behavior, using the Gunma University-type special apparatus for continuous and direct measurement of ambulation and drinking in streptozotocin-induced diabetic rats (STZ, 60 mg/kg). Ambulatory activity of diabetic rats was significantly less t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90366-c

    authors: Shimomura Y,Shimizu H,Takahashi M,Sato N,Uehara Y,Negishi M,Kobayashi I,Kobayashi S

    更新日期:1990-06-01 00:00:00

  • Effect of insulin on endocrine pancreas function during late pregnancy in the rat.

    abstract::To partly or completely satisfy the increasing demand for insulin, pregnant rats were infused SC with human insulin (2.4 or 4.8 IU/day) from day 14 to day 20 of gestation. Cyclic control rats underwent the same procedure of 6 days of insulin-treatment. During the treatment all groups of rats were hypoglycaemic, but fo...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)00080-3

    authors: Wijkstra S,Moes H,Schuiling GA,Koiter TR

    更新日期:1995-09-01 00:00:00

  • Change in the hedonic value of an aversive stimulus in the presence of a pre-exposed odor.

    abstract::Rats exhibit a sensitive period from the time of birth until postnatal day 10 during which they develop preferences for odors even if those odors are paired with a moderately aversive stimulus. It is still unknown whether pre-exposure to an odor produces alterations on intake responses of basic tastants, and on other ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.12.041

    authors: Kamenetzky GV,Suárez AB,Pautassi RM,Mustaca AE,Nizhnikov ME

    更新日期:2015-09-01 00:00:00

  • Dietary obesity in exercising or cold-exposed Syrian hamsters.

    abstract::High-fat diet-feeding increases body weight and adiposity in Syrian hamsters (Mesocricetus auratus), effects due in part to decreased energy expenditure. The effects of voluntary exercise- or cold exposure-induced increases in energy expenditure were examined in fat- or chow-fed, female Syrian hamsters. In Experiment ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(84)90075-1

    authors: Bartness TJ,Ruby NF,Wade GN

    更新日期:1984-01-01 00:00:00

  • Brief but enough: 45-min maternal separation elicits behavioral and physiological responses in neonatal mice and changes in dam maternal behavior.

    abstract::Currently, two gaps exist in the study of early stress response caused by maternal separation (MS) in rodents. Firstly, the influence of brief maternal separation (less than 1 hour) on physiological and behavioral development of offspring is still largely unexplored despite its fundamental and applied value. Secondly,...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.112877

    authors: Burenkova OV,Averkina AA,Aleksandrova EA,Zarayskaya IY

    更新日期:2020-08-01 00:00:00

  • Dawn-song onset coincides with increased HVC androgen receptor expression but is decoupled from high circulating testosterone in an equatorial songbird.

    abstract::The song of songbirds is a testosterone-sensitive behavior that is controlled by brain regions expressing androgen receptors. At higher latitudes, seasonal singing is stimulated by increasing day-length and elevated circulating testosterone. However, a large number of songbird species inhabit equatorial regions under ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.12.027

    authors: Quispe R,Sèbe F,da Silva ML,Gahr M

    更新日期:2016-03-15 00:00:00