Abstract:
:To partly or completely satisfy the increasing demand for insulin, pregnant rats were infused SC with human insulin (2.4 or 4.8 IU/day) from day 14 to day 20 of gestation. Cyclic control rats underwent the same procedure of 6 days of insulin-treatment. During the treatment all groups of rats were hypoglycaemic, but foetal survival was not affected. The low dose treatment prevented the characteristic rise of the insulin response to a glucose challenge during pregnancy, both in vivo and in vitro, while the high dose treatment suppressed the insulin response, as well as the pancreatic insulin content. The insulin responses and insulin contents of pregnant rats were higher than those of the corresponding cyclic control rats. These results support the hypothesis that during gestation the increased insulin demand, due to the actions of placental hormones, is the cause of the increased insulin secretion. However, it cannot be excluded that direct effects of placental hormones on the islets of Langerhans are also involved.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Wijkstra S,Moes H,Schuiling GA,Koiter TRdoi
10.1016/0031-9384(95)00080-3subject
Has Abstractpub_date
1995-09-01 00:00:00pages
445-50issue
3eissn
0031-9384issn
1873-507Xpii
0031-9384(95)00080-3journal_volume
58pub_type
杂志文章abstract::Luxury brand marketers have recently turned their attention to customer-driven social media devoted to their brands. The key concepts of involvement, interaction and behavioral intention provide the theoretical foundation to investigate luxury brands. The purpose of this study is to test a model that analyzes the rela...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2018.03.028
更新日期:2019-03-01 00:00:00
abstract::Leptin is a hormone secreted by adipocytes, which plays an important role in the control of food intake and metabolic processes. In the current study, a dose-dependent relationship was shown between a bolus intracerebroventricular rat recombinant leptin administration and reductions in food intake and body weight in S...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(98)00243-1
更新日期:1999-01-01 00:00:00
abstract::Obesity is a major public health concern and overconsumption of unhealthy fats and sugary beverages are contributing factors. Time-restricted feeding can reduce obesity-associated pathophysiological parameters by limiting the time of food consumption; however, the effects of time-restricted sugary water consumption ar...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.112905
更新日期:2020-09-01 00:00:00
abstract::In this paper we investigated the effect of sex and season on baseline and post-GnRH challenge luteinising hormone (LH) levels in a solitary, seasonally breeding mole-rat. Circulating basal concentrations of luteinising hormone (LH) were found to differ significantly with season in both sexes. However, no significant ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.05.020
更新日期:2006-07-30 00:00:00
abstract::The aim of the study was to investigate the illuminance selected in the morning by subjects whose face was cooled and whose tympanic temperature has been lowered by 0.15-0.25 degrees C. The hypothesis tested was that a difference between the actual core temperature and its set point (load error) will influence the pre...
journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章
doi:10.1016/j.physbeh.2003.12.015
更新日期:2004-03-01 00:00:00
abstract::Minimal hepatic encephalopathy (MHE), which represents the early stage of this condition, is not clinically apparent and is prevalent in up to 80% of patients. The poor outcomes of MHE encouraged us to identify more simple methods for early diagnosis of MHE. To this purpose, we evaluated the contemporary manifestation...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2017.01.033
更新日期:2017-05-01 00:00:00
abstract::Animals living in temperate regions prepare for harsh winter conditions by responding to environmental cues that signal resource availability (e.g., food, day length). Siberian hamsters (Phodopus sungorus) breed in long, summer-like days (LD, >14h light), i.e., photoperiods, and undergo robust gonadal regression and b...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.09.023
更新日期:2016-12-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.physbeh.2015.07.017
更新日期:2015-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90342-5
更新日期:1994-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2005.02.022
更新日期:2005-04-13 00:00:00
abstract::Short- and long-term changes in the composition of dietary macronutrients [protein (P), carbohydrate (C), and fat (F)] alter neurochemistry and behavior in animals. We examined whether short-term intake of a diet rich in P, C, or F affected their anxiety response (AR). AR of Sprague-Dawley rats was measured in an elev...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(96)00135-7
更新日期:1996-09-01 00:00:00
abstract::Glucose and insulin levels of the cerebrospinal fluid (CSF) were changed by an infusion of either glucose, insulin or a mixture of glucose and insulin in the third ventricle of freely moving undisturbed rats. Before, during and after infusions venous blood samples were withdrawn to determine insulin- and glucose conce...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90316-6
更新日期:1985-09-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(02)00650-9
更新日期:2002-04-01 00:00:00
abstract::The effect of infantile handling stimulation on exploratory and emotional behavior of Roman high- and low-avoidance (RHA/Verh and RLA/Verh) weanling rats was investigated. Postnatally handled and nonhandled, 4-week-old males and females from both psychogenetically selected lines were exposed to a hexagonal tunnel maze...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90546-z
更新日期:1991-09-01 00:00:00
abstract::Physical restraint, like many other stressors, can block early pregnancy, but the underlying physiological mechanisms have not been established. Exogenous estrogens in minute doses will also block early pregnancy. In the present study, female rats were exposed to 5 h of restraint daily for the first 5 days after insem...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90446-9
更新日期:1992-07-01 00:00:00
abstract::We have investigated the effects of peripherally administered pyruvate and lactate on the intake of high fat (HF) and low fat (LF) diets by a strain of rat either sensitive (Osborne-Mendel, OM) or resistant (SSB/Pl) to high fat-induced obesity. Both pyruvate and lactate inhibited the intake of HF and LF diets by OM ra...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)02109-4
更新日期:1996-03-01 00:00:00
abstract::We recently showed, using a new immunocytochemical technique, that aromatase-immunoreactive neurons are a specific marker for the sexually dimorphic medial preoptic nucleus (POM) in quail and that the number of these immunoreactive cells is markedly increased by a systemic treatment with testosterone (T). Since the PO...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90158-x
更新日期:1992-02-01 00:00:00
abstract::Calorie restriction (CR) has been promoted to increase longevity. Previous studies have indicated that CR can negatively affect mood and therefore the effect of CR on mood and quality of life (QOL) becomes crucial when considering the feasibility of CR in humans. We conducted a three month clinical trial on CR (reduct...
journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.physbeh.2011.07.007
更新日期:2011-10-24 00:00:00
abstract::Chronic nutritional stress can have a negative impact on an individual's learning ability and memory. However, in social animals that share food among group members, such as the honey bee (Apis mellifera L.), it is unknown whether group-level nutritional stress is manifested in the learning performance of individuals....
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2008.08.003
更新日期:2008-12-15 00:00:00
abstract::In the present work the existence of sex differences (Experiment 1) on the acquisition and extinction of a continuously reinforced response in a short and narrow runway (100 x 9 x 10 cm) were investigated. In addition to the investigation of the basic sex differences in Experiment 1, the effect of postpuberal gonadect...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90230-l
更新日期:1991-01-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00345-4
更新日期:1997-12-01 00:00:00
abstract::Pretreatment with the GABA(A) receptor antagonist, bicuculline or the GABA(B) receptor antagonist, saclofen, into the nucleus accumbens (Nacc) shell, respectively, potentiates and reduces feeding elicited by the mu opioid agonist, [D-Ala(2), Nme(4), Gly-ol(5)]-enkephalin (DAMGO), administered into the same site. DAMGO...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(03)00087-8
更新日期:2003-07-01 00:00:00
abstract::Sufficient oral microelements such as zinc and fully chewing of foods are required to maintain cognitive function despite aging. No knowledge exists about the combination of factors such as zinc deficiency and reduced mastication on learning and memory. Here we show that tooth extraction only in 8-week-old mice did no...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.10.005
更新日期:2015-12-01 00:00:00
abstract::Adult male rats were exposed to single applications of one of three stressful stimuli (low environmental temperature, immobilization, random footshock) for periods up to 4 hours and plasma levels of corticosterone (PCS), fatty acids (PFA), and glucose (PGL) were determined at various points during the stress exposure ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90054-x
更新日期:1985-04-01 00:00:00
abstract::Two experiments examined the feeding behaviour and body weight changes of rats returned to a standard chow diet after prolonged periods of cafeteria feeding. In the first, both overweight (ad lib fed) and 'normal' weight (fed a restricted ration of cafeteria foods) cafeteria rats became hypophagic compared to chow-fed...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90129-5
更新日期:1985-10-01 00:00:00
abstract:BACKGROUND:Negative affect is shown consistently to promote unhealthy food choices and dietary intake in laboratory studies. However, this relationship in naturalistic settings is less clear and previous research is limited by dietary assessment methodology and neglects to account for several important moderating varia...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.05.011
更新日期:2019-08-01 00:00:00
abstract::Previous studies have shown that progesterone can have biphasic activational and inhibitory roles in the regulation of sexual behavior in female Syrian hamsters. The purpose of this study was to determine whether these biphasic effects on sexual behavior are mirrored in a reciprocal regulation of aggression. Ovariecto...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90102-a
更新日期:1990-03-01 00:00:00
abstract::Intracranial self-stimulation (ICSS) of the medial prefrontal cortex (MFC) is acquired gradually, taking 4 or more days to establish. One explanation for this finding is that the stimulation becomes more rewarding with repetition. Four experiments were conducted to test this hypotheses. In Experiment 1, the MFC ICSS f...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90083-6
更新日期:1985-01-01 00:00:00
abstract::Although cooperation represents a long-standing evolutionary puzzle, field studies on social carnivores have contributed greatly to our understanding of the selective forces favoring cooperative breeding. Despite these insights, our grasp of the proximate mechanisms facilitating cooperation in carnivores remains surpr...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2017.11.006
更新日期:2018-09-01 00:00:00
abstract::Previously, a hormone-simulated pregnancy (HSP), and the subsequent 'postpartum' withdrawal in estradiol has been shown to precipitate depressive-like behaviours in the forced swim test in female rats. In this study, we used the HSP and 'postpartum' withdrawal to investigate the impact on sucrose consumption, a model ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2009.02.020
更新日期:2009-05-25 00:00:00