Abstract：
:The Obsessive Compulsive Drinking Scale (OCDS) was developed to reflect obsessionality and compulsivity related to craving and drinking behaviour for revealing in the long-term drop-out, abstinence and relapse. This study evaluates the early OCDS predictive value in drop-out, abstinence and relapse of patients suffering from Alcohol Use Disorders (AUD) for discovering an OCDS total score cut-off capable of disclosing patients most at-risk of relapse during the beginning of the therapeutic intervention in the Day-Hospital period. The sample includes 263 AUD patients, with 192 men and 71 women. The OCDS scores were measured during the two-weeks Day Hospital treatment for detoxification and after 30, 60, 90 and 180 days after discharge. We also investigated the association between the all OCDS scores and abstinence and between craving, relapse and drop-out. We found that high values of OCDS during Day Hospital detoxification may predict a lower ability to maintain abstinence with elevated relapsing probabilities. Surprisingly, early dropping-out AUD people had lower OCDS total scores. However, significant differences in OCDS values in dropping-out AUD people were revealed mainly 90 and 180 days after discharge compared to no dropping-out AUD subjects. Craving measured also after 30, 60, 90 and 180 days from discharge in AUD relapsers, with OCDS values comprised between 6 and 10, could indicate a lower ability to continue abstinence. In conclusion, OCDS may be a useful tool to early discriminate AUD people at-risk for relapse and drop-out and for addressing the specialist to adjust both medical treatment and psychological support during crucial moments of patients' treatment and follow-up.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Ledda R,Battagliese G,Attilia F,Rotondo C,Pisciotta F,Gencarelli S,Greco A,Fiore M,Ceccanti M,Attilia MLdoi
10.1016/j.physbeh.2018.10.009subject
Has Abstractpub_date
2019-01-01 00:00:00pages
67-75eissn
0031-9384issn
1873-507Xpii
S0031-9384(18)30901-6journal_volume
198pub_type
杂志文章abstract：:Thyrotropin-releasing hormone (TRH) and cholecystokinin octapeptide (CCK) are endogenous neuropeptides known to inhibit intake of alcohol. Although both peptides are released by alcohol consumption and are hypothesized to satiate alcohol intake, their interaction has not been examined. We deprived ad-lib-fed male (n=6...
journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90025-7
更新日期：1982-08-01 00:00:00
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pub_type： 历史文章,杂志文章
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更新日期：2021-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2008-02-27 00:00:00
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journal_title：Physiology & behavior
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更新日期：2012-01-18 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.07.034
更新日期：2005-01-31 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90374-b
更新日期：1992-11-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.03.008
更新日期：2006-06-15 00:00:00
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journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
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更新日期：2004-05-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00511-x
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更新日期：1993-12-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1994-10-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1992-09-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1997-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1986-01-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1977-09-01 00:00:00
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journal_title：Physiology & behavior
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更新日期：2017-10-15 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1986-01-01 00:00:00
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更新日期：2015-11-01 00:00:00
