Detection of antibodies to human parvovirus in erythema infectiosum (fifth disease).

abstract：OBJECTIVE:The value of comparative effectiveness trials in informing clinical and policy decisions depends heavily on the choice of control arm (comparator). Our objective is to identify challenges in comparator reasoning and to determine justification criteria for selecting a control arm in paediatric clinical trials....

journal_title：Archives of disease in childhood

authors： Kelly LE,Davies EH,Saint-Raymond A,Tomasi P,Offringa M

更新日期：2016-10-01 00:00:00

abstract：:Adrenal cortical carcinoma in a 4 1/4-month-old girl was treated by surgery in combination with actinomycin D, cyclophosphamide, and 5-fluorouracil given daily for 5 days every third week for 13 1/2 months. Postoperative hypertension and raised 24-hour 17-hydroxy- and 21-oxosteroids suggested residual microscopical tu...

journal_title：Archives of disease in childhood

authors： Visconti EB,Peters RW,Cangir A,Zorn GL Jr,Fisher S

更新日期：1978-04-01 00:00:00

abstract：:Real time ultrasonography of the pelvic organs was performed on 114 normal premenarcheal girls aged between 2 years and 13 years 11 months. Values were obtained for total uterine length, anteroposterior diameters of the corpus and cervix, corpus/cervix ratio, and uterine and ovarian volumes and the resultant data were...

journal_title：Archives of disease in childhood

authors： Salardi S,Orsini LF,Cacciari E,Bovicelli L,Tassoni P,Reggiani A

更新日期：1985-02-01 00:00:00

abstract：:A 9 month old boy presented with acute respiratory distress and was found to have a left pleural effusion. The chylous nature of the effusion, multiple bony lytic lesions, and splenic cysts lead to the diagnosis of congenital lymphangiomatosis with chylothorax. Surgical intervention including pleurectomy was required ...

journal_title：Archives of disease in childhood

authors： Dunkelman H,Sharief N,Berman L,Ninan T

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Data on the efficacy and safety of long-acting β2-agonists (LABA) in children are limited, and current guidelines recommend that LABA always be used with inhaled corticosteroids (ICS). OBJECTIVE:To compare asthma control, assessed by rescue medications use, in children prescribed LABA and ICS as a fixed-dos...

journal_title：Archives of disease in childhood

authors： Elkout H,McLay JS,Simpson CR,Helms PJ

更新日期：2010-10-01 00:00:00

abstract：:Concerns have been expressed in recent years about the decline in children's clinical and biomedical research in the UK, and in the paediatric academic workforce. Here I consider the extent to which these concerns are justified, the sweeping changes that have taken place in research funding, governance and organisatio...

journal_title：Archives of disease in childhood

authors： Modi N

更新日期：2010-11-01 00:00:00

abstract：:To determine the value of a detailed family history for the assessment of the risk of recurrence of febrile seizures, 115 children who visited the emergency room of an academic children's hospital were studied prospectively. The recurrence risk of febrile seizures was analysed in relation to the child's family history...

journal_title：Archives of disease in childhood

authors： van Esch A,Steyerberg EW,Berger MY,Offringa M,Derksen-Lubsen G,Habbema JD

更新日期：1994-05-01 00:00:00

abstract：:Circulating erythroid progenitors (BFU-E) in five anaemic preterm infants (haemoglobin less than 100 g/l) were about 2 and 4.4 times as abundant as in 10 preterm infants who were not anaemic and five healthy adults, respectively, and were significantly more responsive to low concentrations of recombinant human erythro...

journal_title：Archives of disease in childhood

authors： Emmerson AJ,Westwood NB,Rackham RA,Stern CM,Pearson TC

更新日期：1991-07-01 00:00:00

abstract：AIM:To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS:In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical diagnosis of meningococcal disease to intensive care had measurements of total and ionised calcium on admission. Paratho...

journal_title：Archives of disease in childhood

authors： Baines PB,Thomson AP,Fraser WD,Hart CA

更新日期：2000-12-01 00:00:00

abstract：:Hepatitis B virus infection is still a major public health problem worldwide, since more than 350 million people have chronic, lifelong infection and nearly 1 million deaths occur each year owing to complications. Most infections are acquired at birth or during early childhood. Nowadays, low- and middle-income countri...

journal_title：Archives of disease in childhood

authors： Nannini P,Sokal EM

更新日期：2017-07-01 00:00:00

abstract：:We describe the results of a prospective study in which 120 women who developed hypertension in the last trimester of pregnancy were randomly allocated in double blind manner to atenolol or placebo. The mean duration of treatment was five weeks. The only difference between groups during the neonatal period was in resp...

journal_title：Archives of disease in childhood

authors： Reynolds B,Butters L,Evans J,Adams T,Rubin PC

更新日期：1984-11-01 00:00:00

abstract：:This study describes the pattern of oxygen consumption (VO2), rectal temperature (Tr), and acral skin temperature (Tac) in sleeping and resting (awake) burned children nursed in a thermoneutral environment. Measurements of respiratory gas exchange (VO2 and carbon dioxide production (VCO2)) were made using an open circ...

journal_title：Archives of disease in childhood

authors： Childs C,Little RA

更新日期：1994-07-01 00:00:00

abstract：AIMS:The Royal College of Paediatrics and Child Health (RCPCH) Science and Research Department was commissioned by the Department of Health to develop national care pathways for children with allergies: the asthma/rhinitis care pathway is the third such pathway. Asthma and rhinitis have been considered together. These ...

journal_title：Archives of disease in childhood

authors： Vance G,Lloyd K,Scadding G,Walker S,Jewkes F,Williams L,Dixon L,O'Beirne C,Fletcher P,Brown T,Hughes J,Sohi D,Piddock C,Shields M,McKean M,Warner J,Science and Research Department, Royal College of Paediatrics and Child H

更新日期：2011-11-01 00:00:00

abstract：:The fetal heart beat, detected by ultrasound, was recorded for five minutes from 934 antenatal women--266 at 30 to 35 weeks' gestation and 718 at 36 to 41 weeks. Episodes of bradycardia < 100/minute ranging from 5-30 seconds' duration occurred in 3 (1.1%) of the former and in 9 (1.3%) of the latter group. Tachycardia ...

journal_title：Archives of disease in childhood

authors： Southall DP,Richards J,Hardwick RA,Shinebourne EA,Gibbens GL,Thelwall-Jones H,de Swiet M,Johnston PG

更新日期：1980-07-01 00:00:00

abstract：:If cord blood IgE is used to detect those predisposed to become allergic it is important to define appropriately the normal values for this measurement. A commonly cited cut off point is 1.0 IU/ml. We analysed 5353 cord blood samples for IgE by means of an enzyme linked immunosorbent assay. Descriptive statistics of t...

journal_title：Archives of disease in childhood

authors： Kimpen J,Callaert H,Embrechts P,Bosmans E

更新日期：1987-05-01 00:00:00

abstract：:Members of four generations of a family had a defect of serum opsonization for yeast phagocytosis consistent with dominant inheritance. 2 were healthy, one had chronic osteomyelitis, and the fourth developed a fatal illness in infancy characterized by exfoliative dermatitis, diarrhoea, multiple bacterial infections, a...

journal_title：Archives of disease in childhood

authors： Scott H,Moynahan EJ,Risdon RA,Harvey BA,Soothill JF

更新日期：1975-04-01 00:00:00

abstract：:1 case study and a clinical study with laboratory rats examined the question of breast milk jaundice. The case study confirmed clinical diagnosis of breast milk jaundice. The clinical study compared the effects of breast milk and 3alpha, 20beta-pregnanediol on the conjugation of bilirubin and o-aminophenol by rat li...

journal_title：Archives of disease in childhood

authors： Hargreaves T,Piper RF

更新日期：1971-04-01 00:00:00

abstract：OBJECTIVES:To describe common patterns of bath water scald injuries in children, to examine differences between accidental and non-accidental bath water scalds in children, and to examine potential for prevention. DESIGN:A two year six month retrospective analysis of admissions to a specialist burns unit. SETTING:The...

journal_title：Archives of disease in childhood

authors： Yeoh C,Nixon JW,Dickson W,Kemp A,Sibert JR

更新日期：1994-08-01 00:00:00

abstract：INTRODUCTION:Intravenous paracetamol (acetaminophen) has recently been registered for treatment of pain in neonates but the pharmacodynamics, including effects on body temperature, have not been reported. METHODS:A pooled analysis on body temperature recordings in neonates exposed to intravenous paracetamol was perfor...

journal_title：Archives of disease in childhood

authors： Hopchet L,Kulo A,Rayyan M,Verbesselt R,Vanhole C,de Hoon JN,Allegaert K

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Silver-Russell syndrome (SRS) is an imprinted disorder characterised by intrauterine growth retardation, relative macrocephaly, failure to thrive, typical facial phenotype and frequent body asymmetry. Feeding difficulties are frequently noted, but no study described evolution of gastrointestinal signs during...

journal_title：Archives of disease in childhood

authors： Marsaud C,Rossignol S,Tounian P,Netchine I,Dubern B

更新日期：2015-04-01 00:00:00

abstract：:Seven children with precocious puberty were treated with cyproterone acetate and their adrenal function studied. In each child the drug caused significant adrenal hypofunction which was secondary to adrenocorticotrophic hormone suppression. None of these children had clinical evidence of adrenal hypofunction and it is...

journal_title：Archives of disease in childhood

authors： Savage DC,Swift PG

更新日期：1981-03-01 00:00:00

abstract：:In 20 children needing treatment for symptomatic sick sinus syndrome, the average age at presentation was 7.1 years and ranged from 9 months to 18 years. Symptoms were never precise but, in retrospect, 5 children had syncope, 7 had a rapid heart action, 6 had dyspnoea or tachypnoea, 2 had nonspecific chest pains, 2 ha...

journal_title：Archives of disease in childhood

authors： Radford DJ,Izukawa T

更新日期：1975-11-01 00:00:00

abstract：:Because the incidence of both neonatal respiratory distress syndrome and neonatal mortality can be reduced by giving corticosteroids to women expected to deliver preterm and by giving surfactant to babies at high risk of developing hyaline membrane disease, we have considered what effects the adoption of one or both o...

journal_title：Archives of disease in childhood

authors： Mugford M,Piercy J,Chalmers I

更新日期：1991-07-01 00:00:00

abstract：:You can't teach old dogs new tricks. Teaching middle-aged dogs new tricks is hard enough. They tend to stick to particular styles of attacking the postman that over the years have proved pretty reliable, often choosing to ignore new findings, or simply failing to keep up with progress in current discussions on, say, t...

journal_title：Archives of disease in childhood

authors： Cameron D

更新日期：2007-11-01 00:00:00

abstract：:Blood lead concentrations and body iron status were investigated in 279 children. Blood lead concentrations showed no increase during iron depletion phase (stage I) but markedly increased from the phase of iron deficient erythropoiesis (stage II). Increased blood lead concentrations in anaemic subjects significantly d...

journal_title：Archives of disease in childhood

authors： Choi JW,Kim SK

更新日期：2003-09-01 00:00:00

abstract：:Two male patients with congenital cleft lip and palate first seen at ages 10.2 and 21.5 years presented with typical signs of hypothalamic-interior pituitary hormone deficiencies. They were found to lack GH, LH, and FSH and to be partially deficient in TSH and ACTH. Several congenital defects may explain this rare syn...

journal_title：Archives of disease in childhood

authors： Roitman A,Laron Z

更新日期：1978-12-01 00:00:00

abstract：:Forty six of 142 infants weighing less than 1500 g at birth, who had chest radiographs in the first 5 days of life, developed pulmonary interstitial emphysema (PIE) and in 19 this occurred in the first 24 hours. PIE was seen more frequently in infants weighing less than 1000 g at birth (24 of 57) than in those weighin...

journal_title：Archives of disease in childhood

authors： Hart SM,McNair M,Gamsu HR,Price JF

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The number of children and young people (CYP) living with life-limiting and life-threatening conditions is rising. Paediatric palliative care is a relatively new aspect of healthcare, the delivery of which is variable, with a wide range of healthcare and voluntary sector providers involved. Policy recommenda...

journal_title：Archives of disease in childhood

authors： Mitchell S,Morris A,Bennett K,Sajid L,Dale J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The National Institute for Health and Care Excellence (NICE) guidance for referral of children with suspected cancer was first published in 2005 and updated in 2015. The updated version relied on sparse primary care evidence and published without input from key stakeholders, for example, acute general paedia...

journal_title：Archives of disease in childhood

authors： Murray MJ,Ruffle A,Lowis S,Howell L,Shanmugavadivel D,Dommett R,Gamble A,Shenton G,Nicholson J

更新日期：2020-03-01 00:00:00

abstract：:Thirty-two children with a past diagnosis of coeliac disease were reinvestigated by means of gluten challenge. They had received a gluten-free diet for a mean period of 6-5 years (range 0-25-11-0) before gluten challenge, and had a mean age of 9-9 years (range 3-0-15-3) at the onset of challenge. Small intestinal biop...

journal_title：Archives of disease in childhood

authors： Packer SM,Charlton V,Keeling JW,Risdon RA,Ogilvie D,Rowlatt RJ,Larcher VF,Harries JT

更新日期：1978-06-01 00:00:00