Breast milk jaundice. Effect of inhibitory breast milk and 3 alpha, 20 abeta-pregnanediol on glucuronyl transferase.

abstract：OBJECTIVES:To explore how parents navigate urgent and emergency care (U&EC) services when their child <5 years old has a feverish illness, their views of that experience and whether services are meeting their needs and triaging in line with national guidance. DESIGN:Parents of a febrile child <5 years old contacting a...

journal_title：Archives of disease in childhood

authors： Maguire S,Ranmal R,Komulainen S,Pearse S,Maconochie I,Lakhanpaul M,Davies F,Kai J,Stephenson T,RCPCH Fever Project Board.

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity. AIM:To determine the incidence and risk factors for skeletal morbidity in ALL children. PATIENTS AND METHODS:The medical records of all (n=186, boys=110) children presenting to a single centre ...

journal_title：Archives of disease in childhood

authors： Elmantaser M,Stewart G,Young D,Duncan R,Gibson B,Ahmed SF

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The primary aim was to evaluate the efficacy of financial incentives for reducing paediatric tobacco smoke exposures (TSEs) through motivating cigarette usage reduction among low-income maternal caregivers and members of their social network. DESIGN:Randomised control pilot trial over a 6-month study follow...

journal_title：Archives of disease in childhood

authors： Jassal MS,Lewis-Land C,Thompson RE,Butz A

更新日期：2020-10-01 00:00:00

abstract：:Experience gained from liver studies in 450 patients with cystic fibrosis, seen in a 38 year period from 1964 to 1992, is surveyed. Of these, 31 (7%) showed findings that indicated multilobular cirrhosis. There was a slight but not significant male predominance: 19 males against 12 females. Liver disease had its onset...

journal_title：Archives of disease in childhood

authors： Feigelson J,Anagnostopoulos C,Poquet M,Pecau Y,Munck A,Navarro J

更新日期：1993-05-01 00:00:00

abstract：:A review of 105 children with urinary tract infection showed an increasing prevalence of grades II-III vesicoureteric reflux with diminishing age. During infancy reflux was almost always severe, and affected boys as often as girls. Radiologically scarred kidneys were drained by refluxing ureters in 98% of cases. The p...

journal_title：Archives of disease in childhood

authors： Shah KJ,Robins DG,White RH

更新日期：1978-03-01 00:00:00

abstract：:Six families with at least one infant each with confirmed ornithine transcarbamylase deficiency were investigated by DNA analysis. All the affected sons had died, and no DNA had been stored. Using the restriction endonucleases MspI and Bam HI three restriction fragment length polymorphisms were detected which led to e...

journal_title：Archives of disease in childhood

authors： Svirklys LG,Wilcken B,Hammond J,Mackinlay AG,O'Sullivan WJ

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:To assess the benefit of nebulised amiloride added to the standard inpatient treatment of a respiratory exacerbation in cystic fibrosis. DESIGN:Prospective, randomised, double blind, placebo controlled trial. SUBJECTS:27 cystic fibrosis patients (mean age 12.8 years). SETTING:Two hospitals in Leeds, UK. R...

journal_title：Archives of disease in childhood

authors： Bowler IM,Kelman B,Worthington D,Littlewood JM,Watson A,Conway SP,Smye SW,James SL,Sheldon TA

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:The value of comparative effectiveness trials in informing clinical and policy decisions depends heavily on the choice of control arm (comparator). Our objective is to identify challenges in comparator reasoning and to determine justification criteria for selecting a control arm in paediatric clinical trials....

journal_title：Archives of disease in childhood

authors： Kelly LE,Davies EH,Saint-Raymond A,Tomasi P,Offringa M

更新日期：2016-10-01 00:00:00

abstract：:Necrotising pneumonia in young, previously healthy patients due to Panton-Valentine leucocidin (PVL) producing Staphylococcus aureus has been increasingly recognised. PVL pneumonia is often associated with influenza co-infection and high mortality. This case report describes the successful management of the first docu...

journal_title：Archives of disease in childhood

authors： Obando I,Valderrabanos ES,Millan JA,Neth OW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Children with type 1 diabetes should be encouraged to participate in physical activity because exercise can benefit insulin sensitivity and improve known risk factors for atherosclerosis. METHODS:Physical activity patterns of 127 children and adolescents with stable type 1 diabetes were investigated by 24 h...

journal_title：Archives of disease in childhood

authors： Massin MM,Lebrethon MC,Rocour D,Gérard P,Bourguignon JP

更新日期：2005-12-01 00:00:00

abstract：:All 212 neonates undergoing cardiac surgery at this hospital during the 5-year period from 1976 to 1980 inclusive were reviewed. Forty required open heart surgery with 23 (57%) deaths. One hundred and seventy-four neonates underwent non-bypass procedures and could be divided into three groups: group 1 (82 patients) ha...

journal_title：Archives of disease in childhood

authors： Bove EL,Bull C,Stark J,de Leval M,Macartney FJ,Taylor JF

更新日期：1983-02-01 00:00:00

abstract：:An 11 year old boy presented with severe acute hereditary coproporphyria. Despite supportive measures his condition deteriorated after admission. Haem arginate, started two days after presentation, produced appreciable inhibition of porphyrin precursor overproduction and clinical improvement. ...

journal_title：Archives of disease in childhood

authors： Manning DJ,Gray TA

更新日期：1991-06-01 00:00:00

abstract：:There is little high quality evidence on which to base the management of bone and joint infections in children. This pragmatic practice note aims to provide a consensus framework of best current practice prior to the availability of data from large national randomised controlled trials. For straightforward infection i...

journal_title：Archives of disease in childhood

authors： Faust SN,Clark J,Pallett A,Clarke NM

更新日期：2012-06-01 00:00:00

abstract：:We studied the effects on the family of childhood chronic renal failure by contrasting children with varying degrees of severity of illness with healthy controls. Disruption of family life was most common in families with the more severely ill children (on hospital haemodialysis) and there was a tendency for more ment...

journal_title：Archives of disease in childhood

authors： Reynolds JM,Garralda ME,Jameson RA,Postlethwaite RJ

更新日期：1988-07-01 00:00:00

abstract：AIMS:To pilot a novel approach to providing pharmaceutical care to paediatric inpatients using structured referral and assessment tools. Using standardised referral criteria to ensure patients are assessed by appropriately skilled pharmacists. METHOD:Three wards of varying acuity and specialism were selected in a tert...

journal_title：Archives of disease in childhood

authors： Mott A,Kafka S,Sutherland A

更新日期：2016-09-01 00:00:00

abstract：:A family with multiple congenital scalp defects, over two generations and probably genetically determined, is described. Although alarming in appearance, surgical intervention is not indicated at least for small lesions. The risk of haemorrhage and meningitis is emphasized. ...

journal_title：Archives of disease in childhood

authors： Lassman LP,Sims DG

更新日期：1975-12-01 00:00:00

abstract：:A total of 37 children with refractory wide-spread atopic eczema were treated with an antigen avoidance regimen comprising hospitalisation, exclusive feeding with an elemental formula for a median duration of 30 days, and measures to reduce exposure to pet and dust mite antigens at home. After the initial period of fo...

journal_title：Archives of disease in childhood

authors： Devlin J,David TJ,Stanton RH

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:The number of children and young people (CYP) living with life-limiting and life-threatening conditions is rising. Paediatric palliative care is a relatively new aspect of healthcare, the delivery of which is variable, with a wide range of healthcare and voluntary sector providers involved. Policy recommenda...

journal_title：Archives of disease in childhood

authors： Mitchell S,Morris A,Bennett K,Sajid L,Dale J

更新日期：2017-10-01 00:00:00

abstract：:The decision to participate in infant screening often rests with parents. Medical ethics require that parental decision is elicited from informed choice. Such a decision is influenced by the parental knowledge and attitude towards screening and a careful evaluation of these factors is essential in seeking informed con...

journal_title：Archives of disease in childhood

authors： Olusanya BO,Luxon LM,Wirz SL

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the glycaemic profile of patients with cystic fibrosis using a continuous glucose monitoring system (CGMS), and to evaluate the associations of glycaemic abnormalities with sex, age, pubertal stage, CFTR gene mutations, nutritional status, lung function, oral glucose tolerance te...

journal_title：Archives of disease in childhood

authors： Zorrón Mei Hsia Pu M,Gonçalves AC,Minnicucci WJ,Morcillo AM,Ribeiro JD,Ribeiro AF

更新日期：2018-06-01 00:00:00

abstract：:A problem-orientated case record was used for the investigation and management of neonatal jaundice. Investigation of babies requiring phototherapy rarely showed any abnormality but we consider that such routine investigations are worth retaining. There were problems in the interpretation of moderately low plasma conc...

journal_title：Archives of disease in childhood

authors： Mathew PM,Wharton BA

更新日期：1981-12-01 00:00:00

abstract：:The case is reported of an infant with hyperammonaemia secondary to severe distal renal tubular acidosis. A clinical association between increased concentrations of ammonia in serum and renal tubular acidosis has not previously been described. In response to acidosis the infant's kidneys presumably increased ammonia s...

journal_title：Archives of disease in childhood

authors： Miller SG,Schwartz GJ

更新日期：1997-11-01 00:00:00

abstract：:Of the 265 children aged between 6 and 18 months admitted to hospital in a 26-month period each with his first febrile convulsion, there were 64 who satisfied our criteria for a simple febrile convulsion. Of these, 43 (random) were entered into a double-blind trial of continuous sodium valproate versus phenobarbitone,...

journal_title：Archives of disease in childhood

authors： Ngwane E,Bower B

更新日期：1980-03-01 00:00:00

abstract：:Over a period of 30 months, umbilical artery catheters were inserted in 229 infants. The main complications were haemorrhage, infection, and obstruction of a blood vessel. The incidence of infection was not affected by the use of prophylactic antibiotics. Vascular obstruction was more common in small infants, and in t...

journal_title：Archives of disease in childhood

authors： van Vliet PK,Gupta JM

更新日期：1973-04-01 00:00:00

abstract：:Total DNA was estimated in the lungs of 80 fetuses and newborn infants varying in gestation from 14 weeks to term. In fetuses of appropriate weight for gestational age total lung DNA increased at a constant rate from about 35 mg at 17 weeks' gestation to 480 mg at term. The lungs of immature fetuses were heavier and c...

journal_title：Archives of disease in childhood

authors： Wigglesworth JS,Desai R

更新日期：1981-08-01 00:00:00

abstract：:There may be insufficient awareness of dopa responsive dystonia (DRD), which has a characteristic diurnal variation of symptoms. Two children are reported in whom the diagnosis of DRD was missed. The first was thought to have hysteria and the second hereditary spastic paraparesis. A full history is vital for the diagn...

journal_title：Archives of disease in childhood

authors： Patel K,Roskrow T,Davis JS,Heckmatt JZ

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Phenobarbital (PB), commonly used as the preferred treatment for neonatal seizure, is a drug that requires careful dose adjustments based on therapeutic drug monitoring. It has been reported that PB metabolism was affected by cytochrome P450 (CYP)2C19 polymorphisms in adults requiring dose adjustment. AIM:T...

journal_title：Archives of disease in childhood

authors： Lee SM,Chung JY,Lee YM,Park MS,Namgung R,Park KI,Lee C

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To describe the recent trends in demographic, clinical and microbiological characteristics and outcome of treatment in paediatric cases of tuberculosis. DESIGN:National surveillance study. SETTING:England and Wales. PATIENTS:All children under the age of 16 years reported with tuberculosis to the national ...

journal_title：Archives of disease in childhood

authors： Abubakar I,Laundy MT,French CE,Shingadia D

更新日期：2008-12-01 00:00:00

abstract：:During June and July 1977 5 junior boys in a boarding school for 800 pupils became ill with a mild infection caused by Coxsackie B1. The school had been taking part in a vaccine trial, and paired blood samples had been taken from new entrants in October 1976 and October 1977. 18% of the boys susceptible to the infecti...

journal_title：Archives of disease in childhood

authors： Hoskins TW,Davies JR,Smith AJ,Collingham K,Chamberlain RN

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:To simultaneously record tracheal and oesophageal pH in mechanically ventilated children to determine: (1) the feasibility and safety of the method; (2) the incidence of gastro-oesophageal reflux (GOR) and pulmonary contamination; and (3) their associated risk factors. DESIGN:Prospective study. SETTING:Paed...

journal_title：Archives of disease in childhood

authors： Hue V,Leclerc F,Gottrand F,Martinot A,Crunelle V,Riou Y,Deschildre A,Fourier C,Turck D

更新日期：1996-07-01 00:00:00