Effects of cytochrome P450 (CYP)2C19 polymorphisms on pharmacokinetics of phenobarbital in neonates and infants with seizures.

abstract：:Spirometric data from 1586 healthy children, who did not smoke, were analysed to examine the effects of overweight as measured by the body mass index (weight/height2) on lung function. Overweight (72 boys, 88 girls) was defined as on or above the 90th percentile weight for height. After having controlled for the confo...

journal_title：Archives of disease in childhood

authors： Fung KP,Lau SP,Chow OK,Lee J,Wong TW

更新日期：1990-05-01 00:00:00

abstract：:A cohort of 164 children born within the defined boundaries of greater Manchester during the years 1981 to 1984 inclusive were identified as having bilateral sensorineural hearing loss, giving a prevalence of 1.2/1000 population of 1/817 births. Ninety three children developed an additional conductive hearing loss sec...

journal_title：Archives of disease in childhood

authors： Das VK

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Children with severe malnutrition (SAM) present to hospital with an array of complications, resulting in high mortality despite adherence to WHO guidelines. Diagnostic resources in developing countries are limited and bedside tests could help identify high-risk children. Dipstick urinalysis is a bedside scre...

journal_title：Archives of disease in childhood

authors： Thuo N,Ohuma E,Karisa J,Talbert A,Berkley JA,Maitland K

更新日期：2010-06-01 00:00:00

abstract：:Two cases of atypical Kawasaki disease (KD) manifested as persistent lobar lung consolidation, prolonged fever, and active inflammatory laboratory markers unresponsive to antibiotic treatment are reported. One of the children developed a giant coronary aneurysm. Atypical KD should be considered in the differential dia...

journal_title：Archives of disease in childhood

authors： Uziel Y,Hashkes PJ,Kassem E,Gottesman G,Wolach B

更新日期：2003-10-01 00:00:00

abstract：:The relationship of vesicoureteric reflex (VUR) and renal scarring was studied in 94 children (188 kidneys) with proved urinary tract infection in a district general hospital. There were 61 girls and 33 boys, with nine girls and 17 boys aged less than 1 year, 31 girls and nine boys aged between 1 and 5 years, the rema...

journal_title：Archives of disease in childhood

authors： Gleeson FV,Gordon I

更新日期：1991-11-01 00:00:00

abstract：AIMS:To determine whether the use of negative pressure ventilation (NPV) was associated with a lower rate of endotracheal intubation in infants with recurrent apnoea secondary to acute bronchiolitis. METHODS:Retrospective review of two paediatric intensive care units (PICU) databases and case notes; one PICU offered N...

journal_title：Archives of disease in childhood

authors： Al-balkhi A,Klonin H,Marinaki K,Southall DP,Thomas DA,Jones P,Samuels MP

更新日期：2005-03-01 00:00:00

abstract：:School medical records of 1000 children born in 1981 were studied retrospectively. They showed that once known medical problems and those screened for by the school nurse (hearing, vision, growth) were excluded, only 17 problems requiring treatment were discovered: speech (n = 10), development (n = 3), undescended tes...

journal_title：Archives of disease in childhood

authors： Smith GC,Powell A,Reynolds K,Campbell CA

更新日期：1990-02-01 00:00:00

abstract：:Growth was studied in 83 children with cleft lip and/or palate aged 0-4 years attending a specialist regional centre. Information was collected by a personal interview, postal questionnaire, and record review. The group as a whole grew relatively poorly in early infancy but subsequently recovered, attaining both expec...

journal_title：Archives of disease in childhood

authors： Lee J,Nunn J,Wright C

更新日期：1996-10-01 00:00:00

abstract：:The output of the drug and the particle size produced by various nebulisers were assessed, and sensible nebulisation times for sodium cromoglycate calculated. Three of the four nebuliser systems tested produced over 80% of total drug output within the first five minutes of nebulisation. We suggest that five minutes is...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Clark AR,Milner AD

更新日期：1989-09-01 00:00:00

abstract：:We recorded the respiratory history by questionnaire in a 7 year old cohort of children whose birth weight was under 2000 g and an unselected reference group of local schoolchildren of the same age. Complete data were obtained in 121 low birthweight children (90% of those studied): 62 who had no neonatal respiratory i...

journal_title：Archives of disease in childhood

authors： Chan KN,Elliman A,Bryan E,Silverman M

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:To determine the utility of a novel Paediatric Consultation Assessment Tool (PCAT). DESIGN:Developed to measure clinicians' communication behaviour with children and their parents/guardian, PCAT was designed according to consensus guidelines and refined at a number of stages. Volunteer clinicians provided vi...

journal_title：Archives of disease in childhood

authors： Howells RJ,Davies HA,Silverman JD,Archer JC,Mellon AF

更新日期：2010-05-01 00:00:00

abstract：:Eithe low birthweight infants were studied for their metabolic and hormonal responses to intravenous alimentation when the caloric input was varied. The study was made during three consecutive 12-hour periods, when solutions of glucose, glucose and amino-acids, and glucose and amino-acid and lipids were successively i...

journal_title：Archives of disease in childhood

authors： Rubecz I,Mestyán J,Varga P,Soltész G

更新日期：1979-07-01 00:00:00

abstract：:A study of staff stress and job satisfaction was undertaken in a children's hospice. In addition factors were investigated which might be stressful or which helped staff to manage in difficult circumstances. Three quarters were under comparatively little stress and in general showed very few psychological symptoms but...

journal_title：Archives of disease in childhood

authors： Woolley H,Stein A,Forrest GC,Baum JD

更新日期：1989-01-01 00:00:00

abstract：:Six children with congenital heart disease are described in whom poor growth was found to be due to small-bowel villous atrophy; none was in heart failure and only one was severely cyanosed. Growth improved in all 6 on a gluten-free diet. Gluten enteropathy may be more common than is realised in children with congenit...

journal_title：Archives of disease in childhood

authors： Congdon PJ,Fiddler GI,Littlewood JM,Scott O

更新日期：1982-01-01 00:00:00

abstract：AIM:To assess the value and safety of fasts for investigating hypoglycaemia or suspected metabolic disease. STUDY DESIGN:Review of all diagnostic fasts performed over a 2.5 year period. SETTING:The neonatal intensive care unit and programmed investigation unit at a tertiary referral centre for endocrinology and metab...

journal_title：Archives of disease in childhood

authors： Morris AA,Thekekara A,Wilks Z,Clayton PT,Leonard JV,Aynsley-Green A

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVES:To assess the persistence of serum Haemophilus influenzae type b antibodies and the prevalence of H influenzae type b carriage in a group of preschool age children previously vaccinated in infancy. DESIGN:Names were randomly selected from immunisation records. Families were visited on five occasions over a ...

journal_title：Archives of disease in childhood

authors： Heath PT,Bowen-Morris J,Griffiths D,Griffiths H,Crook DW,Moxon ER

更新日期：1997-12-01 00:00:00

abstract：:The management of neonatal jaundice can be made much easier using simple methods that increase the radiant energy in the range 420 to 480 nm. Two groups of infants being treated for physiological jaundice during a period of 6 months were compared. The first group received treatment from two unmodified phototherapy uni...

journal_title：Archives of disease in childhood

authors： Modi N,Keay AJ

更新日期：1983-06-01 00:00:00

abstract：STUDY OBJECTIVES:To present diagnosis and treatment modalities of children with interstitial lung disease associated with frequent or rare surfactant protein C gene (SFTPC) mutation. PATIENTS:Twenty-two children with chronic lung disease associated with SFTPC mutation in a heterozygous form. RESULTS:Mutations located...

journal_title：Archives of disease in childhood

authors： Thouvenin G,Abou Taam R,Flamein F,Guillot L,Le Bourgeois M,Reix P,Fayon M,Counil F,Depontbriand U,Feldmann D,Pointe HD,de Blic J,Clement A,Epaud R

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of childhood atopic eczema on families and assess the personal financial cost of its management. DESIGN:Cross sectional survey. SETTING:Paediatric dermatology and paediatric diabetology outpatient clinics. PATIENTS:Parents of 48 randomly selected children with atopic eczema and 46 wi...

journal_title：Archives of disease in childhood

authors： Su JC,Kemp AS,Varigos GA,Nolan TM

更新日期：1997-02-01 00:00:00

abstract：:The clinical response to sodium cromoglycate treatment was compared with its concentration in serum. Twenty five children with asthma entered a 10 week trial of two baseline weeks followed by eight weeks of treatment by the inhalation of 20 mg of sodium cromoglycate spincaps four times a day. Individual clinical respo...

journal_title：Archives of disease in childhood

authors： Yahav Y,Dany S,Katznelson D,Farfel Z

更新日期：1988-06-01 00:00:00

abstract：:Serum antitoxoplasma titres were determined simultaneously by the direct agglutination and the indirect immunofluorescent tests in 52 children aged 2 to 16 years having chronic lymph node enlargement, mainly cervical. Direct agglutination titres were raised (64 to 4096) in 22 children (42%), but rarely in the control ...

journal_title：Archives of disease in childhood

authors： Thomaidis T,Anastassea-Vlachou K,Mandalenaki-Lambrou C,Theodoridis C,Vrahnou E

更新日期：1977-05-01 00:00:00

abstract：:An increased incidence of E. coli sepsis has been observed in neonates given intramuscular iron-dextran for prevention of iron deficiency. Mechanisms for this apparent effect on susceptibility to infection were investigated by comparing phagocytic and antibacterial functions in paired samples of venous blood from 7 in...

journal_title：Archives of disease in childhood

authors： Becroft DM,Dix MR,Farmer K

更新日期：1977-10-01 00:00:00

abstract：:To assess the bacteriological quality of unpooled expressed breast milk, a pilot bottle sample of each donation was examined before the milk was given to the neonate. Provided the milk did not contain greater than 2500 organisms/ml or potential pathogens it was used unheated. Milk containing between 2500 and 5000 orga...

journal_title：Archives of disease in childhood

authors： Davidson DC,Poll RA,Roberts C

更新日期：1979-10-01 00:00:00

abstract：:Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the age-appropriateness of the formulation. Generally, the younger the child, the more the attention that is required. For decades, there has been a general lack of (authorised) formulations ...

journal_title：Archives of disease in childhood

authors： van Riet-Nales DA,Schobben AF,Vromans H,Egberts TC,Rademaker CM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:There are few data on the optimal micronutrient composition of paediatric enteral feeds. The recent European Directive on Foods for Special Medical Purposes (1999/21/EC) did not distinguish between the composition of adult and paediatric feeds. AIMS:To evaluate, in an open, observational study, the long ter...

journal_title：Archives of disease in childhood

authors： Johnson TE,Janes SJ,MacDonald A,Elia M,Booth IW

更新日期：2002-06-01 00:00:00

abstract：:Monthly increments of length, weight gain, and head circumference were recorded from birth to 4 years of age in 52 children with cystic fibrosis. At birth the children showed stunting. Standard deviation (SD) scores at birth for height, weight, and head circumference were -1.24, -0.72, and -1.82 respectively. Over the...

journal_title：Archives of disease in childhood

authors： Ghosal S,Taylor CJ,Pickering M,McGaw J,Beckles-Willson N,Wales JK

更新日期：1995-02-01 00:00:00

abstract：:Fulminant endocarditis affecting the mitral valve in an 11-year-old boy was caused by a nontoxogenic strain of Corynebacterium diphtheriae. ...

journal_title：Archives of disease in childhood

authors： Horst R,Dyer D,Hallett A

更新日期：1976-03-01 00:00:00

abstract：:A 10 1/2 year old boy presented with raised intracranial pressure and precocious puberty caused by a human chorionic gonadotrophin (HCG) secreting pineal germinoma. After craniospinal irradiation he improved clinically and his HCG concentration fell to an undetectable value. Two years later he remains well. Pineal ger...

journal_title：Archives of disease in childhood

authors： Ahmed SR,Shalet SM,Price DA,Pearson D

更新日期：1983-09-01 00:00:00

abstract：:Total DNA was estimated in the lungs of 80 fetuses and newborn infants varying in gestation from 14 weeks to term. In fetuses of appropriate weight for gestational age total lung DNA increased at a constant rate from about 35 mg at 17 weeks' gestation to 480 mg at term. The lungs of immature fetuses were heavier and c...

journal_title：Archives of disease in childhood

authors： Wigglesworth JS,Desai R

更新日期：1981-08-01 00:00:00

abstract：AIM:Assessment of the efficacy of vitamin D replenishment and maintenance doses required to attain optimal levels in boys with Duchenne muscular dystrophy (DMD). METHOD:25(OH)-vitamin D levels and concurrent vitamin D dosage were collected from retrospective case-note review of boys with DMD at the Dubowitz Neuromuscu...

journal_title：Archives of disease in childhood

authors： Alshaikh N,Brunklaus A,Davis T,Robb SA,Quinlivan R,Munot P,Sarkozy A,Muntoni F,Manzur AY,Dubowitz Neuromuscular Team.

更新日期：2016-10-01 00:00:00