Abstract:
:We recorded the respiratory history by questionnaire in a 7 year old cohort of children whose birth weight was under 2000 g and an unselected reference group of local schoolchildren of the same age. Complete data were obtained in 121 low birthweight children (90% of those studied): 62 who had no neonatal respiratory illness, 25 who had oxygen treatment only, and 34 who received mechanical ventilation (of whom 10 had bronchopulmonary dysplasia). The low birthweight children were no more likely to wheeze than the reference group, but frequent and troublesome cough was significantly more common, especially among children of very low birth weight (under 1500 g) who had received neonatal respiratory treatment. Neonatal mechanical ventilation was not associated with increased symptoms when compared with neonatal oxygen treatment alone. The prevalence of cough at the age of 7 was independently associated with the level of neonatal intensive care as defined by oxygen score. Although there was no excess of wheeze in the cohort compared with the reference group, there was a weak correlation between wheeze and the neonatal oxygen score as well as with maternal smoking. Loss of schooling due to respiratory symptoms in the nine months before this study was no greater in children of low birth weight than in the reference group.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Chan KN,Elliman A,Bryan E,Silverman Mdoi
10.1136/adc.64.9.1294subject
Has Abstractpub_date
1989-09-01 00:00:00pages
1294-304issue
9eissn
0003-9888issn
1468-2044journal_volume
64pub_type
杂志文章abstract:OBJECTIVE:There are no objective ambulatory studies on the temporal relationship between reflux and cough in children. Commercial pHmetry loggers have slow capture rates (0.25 Hz) that limit objective quantification of reflux and cough. The authors aimed to evaluate if there is a temporal association between cough and ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2009.177733
更新日期:2011-05-01 00:00:00
abstract::Cerebral palsy comprises an important component of paediatric and obstetric practice and has major medico-legal implications. The prognosis for survival in cerebral palsy determines the financial provision made in cases that come to litigation. Issues of data quality and estimation methods are critical. Estimating the...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/adc.2005.075002
更新日期:2006-03-01 00:00:00
abstract::There was much speculation about the potential impact of the Human Rights Act 1998 on established principles of health care practice. Now the statute has been "bedded in", predictions that existing good practice would not fall foul of the legislation provided it was demonstrable, have proved to be broadly accurate. Th...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/adc.2003.037218
更新日期:2004-05-01 00:00:00
abstract::An usually high rate of both tuberculosis infection and active disease is reported in 11 of 38 nursery children in contact with a case of smear positive pulmonary tuberculosis, emphasising the susceptibility of young children to this disease. This report also underlines some important principles in case finding and di...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.82.5.386
更新日期:2000-05-01 00:00:00
abstract::Analysis of the growth abnormalities in sickle cell disease has been limited by the lack of longitudinal observations in individuals, and by an inability to quantitate the observed patterns. To investigate the timing and pattern of the adolescent growth spurt, longitudinal observations of height from the Jamaican coho...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.71.5.404
更新日期:1994-11-01 00:00:00
abstract::Data are presented on 25 children under 2 years of age with acute renal failure treated by peritoneal dialysis. The clinical features, treatment, complications, and outcome of the illnesses are described. 22 (88%) survived, and though the incidence of serious complications during the illness was high most regained ful...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.6.459
更新日期:1976-06-01 00:00:00
abstract:BACKGROUND:Growth hormone insufficiency (GHI) is diagnosed conventionally by short stature and slow growth, and is confirmed by diminished peak GH response to a provocation test. Insulin-like growth factor I (IGF-I) and IGF binding protein 3 (IGFBP-3) have previously been considered individually OBJECTIVE:To test the ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.80.5.443
更新日期:1999-05-01 00:00:00
abstract::Analysis of the response to corticosteroid therapy in a personal series of 8 consecutive cases of dermatomyositis in childhood shows that there are advantages in a moderate dosage, short-term treatment schedule, with gradual tapering of the dosage as soon as there is clinical improvement without waiting for full remis...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.7.494
更新日期:1976-07-01 00:00:00
abstract::Since its first description optic nerve hypoplasia has been identified with increasing frequency, and a range of associated problems have been described. The major neurological and endocrine associations are well established, but those factors that predispose to the development of optic nerve hypoplasia remain unclear...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.1.103
更新日期:1990-01-01 00:00:00
abstract::The foot length, occipito-frontal head circumference (OFC), crown-rump, and crown-heel length (CHL) of 123 neonates of gestational ages 26-42 weeks, were measured between 12 hours and 5 days. A gauge, designed and constructed at St Mary's Hospital, Manchester, was used to measure foot length. In term babies (37-42 wee...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.3.226
更新日期:1979-03-01 00:00:00
abstract::162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused pronounced side effects, and the mortality was 4.9%. The most common complications were infections: sep...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.9.664
更新日期:1980-09-01 00:00:00
abstract::Bilateral staghorn renal calculi in a 7-year-old girl with cystinuria were dissolved over a period of 6 months, using a high fluid intake, urinary alkalinisation, and D-penicillamine. Even in children with extensive cystine urolithiasis, medical management may avert the need for surgery. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.10.795
更新日期:1979-10-01 00:00:00
abstract::When children are considered for participation in research, British and international guidelines suggest that they should provide assent in addition to their parents' consent. However, examination of these guidelines shows there is confusion regarding the concept of assent. Furthermore, the need for assent may cause p...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2011.211342
更新日期:2011-10-01 00:00:00
abstract::The term Ehlers-Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many s...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2013-304822
更新日期:2015-01-01 00:00:00
abstract::Twenty five patients with encephalitis were studied prospectively, and their clinical and virological features compared with outcome. Among 22 patients with laboratory confirmation of virus infection, evidence of direct effect on the central nervous system by the virus occurred significantly more often both in those w...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.11.1156
更新日期:1987-11-01 00:00:00
abstract::Primary ciliary dyskinesia was shown in a 12 year old boy with bronchiectasis who had developed hydrocephalus in the neonatal period. The possible relevance of his ciliary abnormality is discussed. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.5.481
更新日期:1984-05-01 00:00:00
abstract::Hepatitis B virus infection is still a major public health problem worldwide, since more than 350 million people have chronic, lifelong infection and nearly 1 million deaths occur each year owing to complications. Most infections are acquired at birth or during early childhood. Nowadays, low- and middle-income countri...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2016-312043
更新日期:2017-07-01 00:00:00
abstract::Retrospective analysis of glycosylated haemoglobin concentrations in a diabetic outpatient clinic over three and a half years showed a small seasonal variation in the mean value with a peak in mid February and a nadir in mid August. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.9.959
更新日期:1987-09-01 00:00:00
abstract::Interferon is becoming the standard treatment in adults for chronic hepatitis C. Twenty one children with histologically proved chronic hepatitis C (10 boys, range 2.5-13 years), who were otherwise healthy, were enrolled in a randomised controlled study to test their response to interferon alfa. Eleven children were t...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.74.2.152
更新日期:1996-02-01 00:00:00
abstract::We describe a prospective study in which we investigated why children fail to get vaccinated against whooping cough, including an assessment of the attitudes of parents and professionals and the impact of different views of the contraindications. There was considerable disagreement among the professionals on the inter...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.4.382
更新日期:1986-04-01 00:00:00
abstract::Administration of 1 alpha-OH-D3 to hypocalcaemic neonates (mean +/- SD, serum calcium 1.50 +/- 0.13 mmol/l) significantly increased serum calcium in all 24 infants within 48 hours after starting therapy (mean +/- SD 1.83 +/- 0.23 mmol/1). The time required to correct hypocalcaemia was significantly shorter (2.04 +/- 0...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.8.642
更新日期:1979-08-01 00:00:00
abstract::A total of 121 infants entered a cohort serological study of primary infections with herpes-viruses. All of them had seven samples of blood available: the first sample was taken soon after birth, the other six were taken at 1, 2, 3, 6, 12, and 14 months of age. One sample of maternal blood was collected immediately af...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.3.408
更新日期:1993-03-01 00:00:00
abstract::Three cases of osteoid osteoma and one of benign osteoblastoma in children are described. The main complaint was severe pain which was worse at night; it was relieved by aspirin or other analgesics. The diagnosis was made on clinical and radiological grounds and was confirmed on histological examination of the central...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.6.459
更新日期:1979-06-01 00:00:00
abstract:OBJECTIVE:To examine the risk of disability from unintentional injury in teenagers and young adults. METHODS:Analyses of data from the National Child Development Study, a follow up study of 98% of all children born in England, Scotland, and Wales in one week in March, 1958. In 1981, 12,537 study participants, 76% of t...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.2.156
更新日期:1996-08-01 00:00:00
abstract::Respiratory timing was studied in 100 babies ventilated for respiratory distress syndrome (RDS) during a brief period of continuous positive airway pressure. For the 76 spontaneously breathing babies the mean (SD) inspiratory and expiratory times were 0.31 (0.06) and 0.41 (0.12) seconds. Respiratory rate was predomina...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.67.4_spec_no.446
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND:Mentoring is important for personal and professional development of doctors. Peer mentoring is a core skill in the UK paediatric postgraduate curriculum. However, there is a paucity of peer mentoring programmes aimed at postgraduate doctors in training (postgraduate trainees), and there are no such schemes w...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2013-304277
更新日期:2014-02-01 00:00:00
abstract::Intestinal D-fructose absorption in 31 children was investigated using measurements of breath hydrogen. Twenty five children had no abdominal symptoms and six had functional bowel disorders. After ingestion of fructose (2 g/kg bodyweight), 22 children (71%) showed a breath hydrogen increase of more than 10 ppm over ba...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.8.735
更新日期:1984-08-01 00:00:00
abstract::Unexpected stability of arterial oxygen and carbon dioxide tensions occurred in infants recovering from respiratory distress syndrome (RDS) on the abrupt withdrawal of CPAP at 6 cmH2O pressure. 30 preterm infants (birthweights 880--3200 g gestational ages 29--38 weeks) were treated at a mean age of 10 hours and for a ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.9.722
更新日期:1979-09-01 00:00:00
abstract::The influence of physical housing quality on childhood asthma expression, especially the effect of exposure to moulds, allergens, and pollutants, is well documented. However, attempts to explain increasing rates and severity of childhood asthma solely through physical environmental factors have been unsuccessful, and ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/adc.2006.098376
更新日期:2006-11-01 00:00:00
abstract::After the introduction of the colposcope for the examination of children suspected of being sexually abused in Leeds, a study was undertaken to describe the findings in detail. A total of 109 consecutive prepubertal girls, mean age 70.4 months were assessed including colposcopic genital and anal examination, and peer ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.73.5.465
更新日期:1995-11-01 00:00:00