Why nebulise for more than five minutes?

abstract：:We have measured total work of breathing before and after the inhalation of water, salbutamol, and ipratropium bromide, given as nebulised solutions, in 39 studies on 25 infants with acute, severe bronchiolitis. Twenty minutes after nebulised water, mean work of breathing per minute was increased by 4% and work per li...

journal_title：Archives of disease in childhood

authors： Stokes GM,Milner AD,Hodges IG,Henry RL,Elphick MC

更新日期：1983-04-01 00:00:00

abstract：:Attention deficit-hyperactivity disorder (ADHD) remains a controversial disorder, despite it now being a well validated clinical diagnosis. Ethical and legal issues are important in determining how doctors should behave in offering a diagnosis or treatment that may generate strong and unpredictable reactions from chil...

journal_title：Archives of disease in childhood

authors： Foreman DM

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Short-course oral corticosteroids are commonly used in children but are known to be associated with adverse drug reactions (ADRs). This review aimed to identify the most common and serious ADRs and to determine their relative risk levels. METHODS:A literature search of EMBASE, MEDLINE, International Pharmac...

journal_title：Archives of disease in childhood

authors： Aljebab F,Choonara I,Conroy S

更新日期：2016-04-01 00:00:00

abstract：:Patient triggered ventilation was assessed in 14 neonates (gestational age 24-40 weeks). Inspiratory changes in airflow, monitored by a pneumotachograph, were used to trigger the ventilator and this was not associated with complications. Patient triggered ventilation was maintained for up to eight hours (mean duration...

journal_title：Archives of disease in childhood

authors： Greenough A,Pool J

更新日期：1988-04-01 00:00:00

abstract：:Forty four children with acute bronchiolitis were given twice daily chest physiotherapy in addition to standard supportive measures and were compared with 46 controls who were not given physiotherapy. There was no clinically discernable benefit on the course of their illness. ...

journal_title：Archives of disease in childhood

authors： Webb MS,Martin JA,Cartlidge PH,Ng YK,Wright NA

更新日期：1985-11-01 00:00:00

abstract：:Respiratory disease is a common cause of morbidity and mortality in children with Down's syndrome (DS). Causes range from those problems common to many children with DS, such as a narrow airway or impaired immunity, to rare structural lesions, such as tracheal bronchus. Additionally, other organ systems or extrinsic f...

journal_title：Archives of disease in childhood

authors： Watts R,Vyas H

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the glycaemic profile of patients with cystic fibrosis using a continuous glucose monitoring system (CGMS), and to evaluate the associations of glycaemic abnormalities with sex, age, pubertal stage, CFTR gene mutations, nutritional status, lung function, oral glucose tolerance te...

journal_title：Archives of disease in childhood

authors： Zorrón Mei Hsia Pu M,Gonçalves AC,Minnicucci WJ,Morcillo AM,Ribeiro JD,Ribeiro AF

更新日期：2018-06-01 00:00:00

abstract：:The benefits of achieving a long term event free survival of 60-70% by using increasingly intense treatment regimens must be weighed against the increased risk of treatment toxicity. From 1985 to 1990, 1612 children with childhood acute lymphoblastic leukaemia (ALL) in the UK were treated on MRC UKALL X with intensive...

journal_title：Archives of disease in childhood

authors： Wheeler K,Chessells JM,Bailey CC,Richards SM

更新日期：1996-02-01 00:00:00

abstract：:Thirty seven healthy infants (18 born at full term and 19 preterm) were studied serially with cross sectional and Doppler echocardiography to compare their postnatal circulatory adaptation. Pulmonary artery pressure was assessed by its inverse relationship with the ratio of pulmonary artery time to peak velocity and r...

journal_title：Archives of disease in childhood

authors： Evans NJ,Archer LN

更新日期：1990-01-01 00:00:00

abstract：:Doppler ultrasound measurements of pulmonary blood flow in 20 babies with severe respiratory distress syndrome treated in a randomised controlled trial of surfactant replacement showed that the immediate improvement of oxygenation was not associated with a significant increase in pulmonary blood flow. Reduction in ven...

journal_title：Archives of disease in childhood

authors： Halliday HL,McCord FB,McClure BG,Reid MM

更新日期：1989-01-01 00:00:00

abstract：:Asthma has little, if any, significant effect on attained adult height. Untreated asthma results in a delay of puberty by approximately 1.3 years, and pubertal delay is likely to explain the majority of apparent growth failure in asthmatics. All currently available inhaled corticosteroids (ICS) result in growth suppre...

journal_title：Archives of disease in childhood

authors： Doull IJ

更新日期：2004-01-01 00:00:00

abstract：AIMS:To document gastroenteritis hospitalisations of the 1995-96 cohort of infants born in Western Australia to mid-2002, and to assess factors associated with their hospitalisations and readmissions. METHODS:Retrospective analysis of the State's hospitalisation data, Midwives' Notification of Births data, the Austral...

journal_title：Archives of disease in childhood

authors： Gracey M,Lee AH,Yau KK

更新日期：2004-08-01 00:00:00

abstract：:36 parents of infants who had died suddenly did not differ in frequency of atopic symptoms, immediate skin tests, IgE, IgE antibody, immunoglobulin G, A, and M, or yeast opsonisation, from 36 matched controls, although atopy was common (about half had atopy in both groups. ...

journal_title：Archives of disease in childhood

authors： Warnasuriya N,Downham MA,Skelton A,Turner MW,Soothill JF

更新日期：1980-11-01 00:00:00

abstract：:Preterm infants with symptomatic patent ductus arteriosus had considerably raised plasma concentrations of atrial natriuretic peptide. Surgical ligation of the patent ductus arteriosus was associated with an immediate fall in plasma atrial natriuretic peptide concentration. Thus left to right shunting and left atrial ...

journal_title：Archives of disease in childhood

authors： Rascher W,Seyberth HW

更新日期：1987-11-01 00:00:00

abstract：:A register has been compiled of the 421 children with congenital cerebral palsy born between 1960 and 1975 from a defined geographical area of North East England (population 770 000). There was a fall in the rate of cerebral palsy among very low birthweight babies between 1964 and 1975 and also in the small group with...

journal_title：Archives of disease in childhood

authors： Jarvis SN,Holloway JS,Hey EN

更新日期：1985-12-01 00:00:00

abstract：:When prescribing drugs for children, it is fundamental to acknowledge that they are distinct from adults with a different physiology and metabolism. They are also still maturing. The development of drugs with a primarily paediatric indication thus requires the trialling of these drugs in a paediatric population to ass...

journal_title：Archives of disease in childhood

authors： Prasad S

更新日期：2005-02-01 00:00:00

abstract：:A 4 year old boy developed a profound motor neuropathy after repeated deliberate inhalation of petroleum vapour. The condition was characterised by extreme slowing of the nerve conduction velocity. He made a gradual recovery over six months. The neuropathy was attributed to the N-hexane component of petroleum. ...

journal_title：Archives of disease in childhood

authors： Hall DM,Ramsey J,Schwartz MS,Dookun D

更新日期：1986-09-01 00:00:00

abstract：:We describe the results of a prospective study in which 120 women who developed hypertension in the last trimester of pregnancy were randomly allocated in double blind manner to atenolol or placebo. The mean duration of treatment was five weeks. The only difference between groups during the neonatal period was in resp...

journal_title：Archives of disease in childhood

authors： Reynolds B,Butters L,Evans J,Adams T,Rubin PC

更新日期：1984-11-01 00:00:00

abstract：:Growth velocity of head circumference was studied longitudinally in different gestational age groups of 222 appropriate-weight-for-dates (AFD) and 94 small-for-dates (SFD) healthy infants during the first 5 months of life. Term AFD and SFD infants showed a steady slowing of growth rate of head circumference from birth...

journal_title：Archives of disease in childhood

authors： Fujimura M,Seryu JI

更新日期：1977-02-01 00:00:00

abstract：AIMS:To investigate a population of individuals with 22q11 deletion syndrome for hypocalcaemia. METHODS:A detailed clinical history enquiring into symptoms of hypocalcaemia and blood sampling to assess for hypocalcaemia and hypoparathyroidism, of patients outside the neonatal period known to have the 22q11 microdeleti...

journal_title：Archives of disease in childhood

authors： Taylor SC,Morris G,Wilson D,Davies SJ,Gregory JW

更新日期：2003-06-01 00:00:00

abstract：:Twenty-one children who had been diagnosed as having laryngomalacia by direct laryngoscopy in infancy were reviewed 7 to 12 years later. The natural history of the disease is documented. A wide variation in the time of onset and duration of the stridor was found and there was a high incidence of feeding difficulties. ...

journal_title：Archives of disease in childhood

authors： McSwiney PF,Cavanagh NP,Languth P

更新日期：1977-03-01 00:00:00

abstract：:162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused pronounced side effects, and the mortality was 4.9%. The most common complications were infections: sep...

journal_title：Archives of disease in childhood

authors： Riikonen R,Donner M

更新日期：1980-09-01 00:00:00

abstract：:The USA has a long-standing paediatric influenza vaccination programme, including use of live attenuated influenza vaccine (LAIV). Following US evidence of apparent lack of vaccine effectiveness (VE) of LAIV in 2015/2016, particularly against A(H1N1)pdm09, the USA suspended the use of LAIV in the 2016/2017 season. The...

journal_title：Archives of disease in childhood

authors： Pebody R,McMenamin J,Nohynek H

更新日期：2018-01-01 00:00:00

abstract：:An 11 year old girl developed progressive upper gastrointestinal ulceration and recurrent episodes of intravenous catheter associated polymicrobial septicaemia. Evaluation failed to establish a cause. After exclusion of the parents and careful surveillance of the patient she improved, supporting the diagnosis of suspe...

journal_title：Archives of disease in childhood

authors： Rubin LG,Angelides A,Davidson M,Lanzkowsky P

更新日期：1986-09-01 00:00:00

abstract：:A survey is reported of infant feeding practice at the time of discharge from a single maternity ward. It is shown that a change in the attitude of nursing staff increased the number of mothers breast feeding their infants and eliminated the practice of giving the infants formula feed complements. This change in attit...

journal_title：Archives of disease in childhood

authors： McKean KS,Baum JD,Sloper K

更新日期：1975-03-01 00:00:00

abstract：:Endogenous formation of thromboxane A2 and prostacyclin were evaluated in seven neonatates with persistent pulmonary hypertension by serial gas chromatographic mass spectrometric determination of their urinary metabolites dinor-thromboxane B2 and dinor-6-keto-prostaglandin F1 alpha, respectively. The patients were stu...

journal_title：Archives of disease in childhood

authors： Kühl PG,Cotton RB,Schweer H,Seyberth HW

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the outcome of percutaneous transluminal angioplasty (PTA) in children with renovascular hypertension (RVH) treated at a single centre over 29 years. METHODS:A retrospective study of the medical charts of all children with RVH who underwent PTA between 1984 and 2012. The primary outcome measurem...

journal_title：Archives of disease in childhood

authors： Kari JA,Roebuck DJ,McLaren CA,Davis M,Dillon MJ,Hamilton G,Shroff R,Marks SD,Tullus K

更新日期：2015-05-01 00:00:00

abstract：:The adrenal glands of 41 fresh stillbirths were studied and a 'stress response' pattern could be seen in 28. In these glands the stress response was characterised by compact cell change, lipid depletion, excess pyroninophilia, and dilatation of the very prominent granular endoplasmic reticulum. Scattered areas of cyto...

journal_title：Archives of disease in childhood

authors： de Sa DJ

更新日期：1978-10-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of subclinical deficits in cognitive and motor function in low birthweight infants. DESIGN:Children of birth weight < or = 2000 g born to mothers resident in Merseyside in 1980-1 assessed using the Wechsler Intelligence Scale for Children (WISC), the Neale analysis of reading abil...

journal_title：Archives of disease in childhood

authors： Pharoah PO,Stevenson CJ,Cooke RW,Stevenson RC

更新日期：1994-04-01 00:00:00

abstract：:The clinical, radiological, and biochemical features of 2 male children with mannosidosis are described. Superficially they appeared to suffer from Hurler's syndrome, but the facies, eye signs, radiological and cytological features were atypical. Excess urinary oligosaccharides were found by thin-layer chromatography....

journal_title：Archives of disease in childhood

authors： Milla PJ,Black IE,Patrick AD,Hugh-Jones K,Oberholzer V

更新日期：1977-12-01 00:00:00