Safe and effective pharmacotherapy in infants and preschool children: importance of formulation aspects.

abstract：:Twenty six children with hypoglycaemia were diagnosed and followed between 1975 and 1995. Diagnosis was confirmed by a high insulin:glucose ratio, and low free fatty acid and 3-hydroxybutyrate on fasting. All patients were treated with diazoxide at a maximum dose of 20 mg/kg/day. Requirement of a higher dose was consi...

journal_title：Archives of disease in childhood

authors： Cresto JC,Abdenur JP,Bergada I,Martino R

更新日期：1998-11-01 00:00:00

abstract：:The output of the drug and the particle size produced by various nebulisers were assessed, and sensible nebulisation times for sodium cromoglycate calculated. Three of the four nebuliser systems tested produced over 80% of total drug output within the first five minutes of nebulisation. We suggest that five minutes is...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Clark AR,Milner AD

更新日期：1989-09-01 00:00:00

abstract：:Albuminuria was studied in 40 diabetic children before and after a standardised exercise test, and also in 21 normal children; the results are expressed as geometric mean (95% range) of urine albumin:urine creatinine ratio (mg/mg). There was no significant difference between the mean resting albumin:creatinine ratio i...

journal_title：Archives of disease in childhood

authors： Jefferson IG,Greene SA,Smith MA,Smith RF,Griffin NK,Baum JD

更新日期：1985-04-01 00:00:00

abstract：:Cryptosporidium spp are a cause of diarrhoea in toddlers. Symptoms and routes of transmission were investigated in a prospective case-control study in the city and surroundings of Basel, Switzerland. Twenty one (4.6%) out of 455 children with diarrhoea who attended paediatric and general practices from June to Septemb...

journal_title：Archives of disease in childhood

authors： Egger M,Mäusezahl D,Odermatt P,Marti HP,Tanner M

更新日期：1990-04-01 00:00:00

abstract：:Patient triggered ventilation was assessed in 14 neonates (gestational age 24-40 weeks). Inspiratory changes in airflow, monitored by a pneumotachograph, were used to trigger the ventilator and this was not associated with complications. Patient triggered ventilation was maintained for up to eight hours (mean duration...

journal_title：Archives of disease in childhood

authors： Greenough A,Pool J

更新日期：1988-04-01 00:00:00

abstract：:The fetal heart beat, detected by ultrasound, was recorded for five minutes from 934 antenatal women--266 at 30 to 35 weeks' gestation and 718 at 36 to 41 weeks. Episodes of bradycardia < 100/minute ranging from 5-30 seconds' duration occurred in 3 (1.1%) of the former and in 9 (1.3%) of the latter group. Tachycardia ...

journal_title：Archives of disease in childhood

authors： Southall DP,Richards J,Hardwick RA,Shinebourne EA,Gibbens GL,Thelwall-Jones H,de Swiet M,Johnston PG

更新日期：1980-07-01 00:00:00

abstract：:When isolated from the female genital tract, diphtheroids are usually regarded as commensal organisms. Corynebacterium kutscheri however is a pathogen in laboratory rodents. We report a case in which C. kutscheri was isolated as a pure culture from the umbilical cord and from other surface sites in an infant. Histolog...

journal_title：Archives of disease in childhood

authors： Fitter WF,de Sa DJ,Richardson H

更新日期：1979-09-01 00:00:00

abstract：:Asthma has little, if any, significant effect on attained adult height. Untreated asthma results in a delay of puberty by approximately 1.3 years, and pubertal delay is likely to explain the majority of apparent growth failure in asthmatics. All currently available inhaled corticosteroids (ICS) result in growth suppre...

journal_title：Archives of disease in childhood

authors： Doull IJ

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Paediatric early warning scores (PEWS) are widely used as an adjunct to support staff in recognising deterioration in hospitalised children. Relatively little is known about how staff use these systems. OBJECTIVE:To examine the completeness and accuracy of PEWS recording in hospitalised children in a tertia...

journal_title：Archives of disease in childhood

authors： Chapman SM,Oulton K,Peters MJ,Wray J

更新日期：2019-12-01 00:00:00

abstract：AIM:To determine the association between allergic rhinitis, bottle feeding, non-nutritive sucking habits, and malocclusion in the primary dentition. METHODS:Data were collected on 1160 children aged 4-5 years, who had been longitudinally followed since the age of 4 months, when they were admitted to nurseries in a sub...

journal_title：Archives of disease in childhood

authors： Vázquez-Nava F,Quezada-Castillo JA,Oviedo-Treviño S,Saldivar-González AH,Sánchez-Nuncio HR,Beltrán-Guzmán FJ,Vázquez-Rodríguez EM,Vázquez Rodríguez CF

更新日期：2006-10-01 00:00:00

abstract：:The association between measurements of lateral ventricle area (determined by serial ultrasound scans) and outcome was studied in 70 preterm neonates of 33 weeks' gestation or less. The study group was subdivided into four groups according to cranial ultrasonographic findings at 2 weeks postnatal age: group A (n = 15)...

journal_title：Archives of disease in childhood

authors： Saliba E,Bertrand P,Gold F,Marchand S,Laugier J

更新日期：1990-10-01 00:00:00

abstract：:In 100 patients with cystic fibrosis the severity of steatorrhoea was assessed by three separate methods. Using chemical faecal fat assay as the gold standard, two other rapid and inexpensive methods were compared with it. The steatocrit method proved unreliable in our hands and gave little indication of the presence ...

journal_title：Archives of disease in childhood

authors： Walters MP,Kelleher J,Gilbert J,Littlewood JM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Data on acute paediatric anaphylaxis presentations to the emergency department (ED) are limited. All allergic presentations to one Australian paediatric ED were studied to determine epidemiological, clinical, and outcome data. METHODS:Retrospective, case based study of patients under 16 years atten...

journal_title：Archives of disease in childhood

authors： Braganza SC,Acworth JP,Mckinnon DR,Peake JE,Brown AF

更新日期：2006-02-01 00:00:00

abstract：:The clinical course of 6 children with primary intestinal lymphangiectuasia who have been treated with low fat medium chain triglyceride-supplemented diets for between 3 and 8 years (4 for longer than 5 years) is described. Though laboratory findings indicate continuing chyle leak, evidence for long-term benefit from ...

journal_title：Archives of disease in childhood

authors： Tift WL,Lloyd JK

更新日期：1975-04-01 00:00:00

abstract：:Somatomedin activity was assayed in the plasma of children suffering from protein calorie malnutrition by a bioassay using rat cartilage and expressed as sulphate uptake ratio. The sulphate uptake ratio was particularly reduced in kwashiorkor. In marasmus there was a slight reduction and the levels were still in the n...

journal_title：Archives of disease in childhood

authors： Mohan PS,Jaya Rao KS

更新日期：1979-01-01 00:00:00

abstract：:Fine needle aspiration biopsy (FNAB) offers a simple outpatient technique for specimen collection in child tuberculosis suspects with peripheral lymphadenopathy. To perform FNAB with mycobacterial culture on an outpatient basis requires use of a sterile transport medium to facilitate bedside inoculation, maintain orga...

journal_title：Archives of disease in childhood

authors： Wright CA,Bamford C,Prince Y,Vermaak A,Hoek KG,Marais BJ,Warren RM

更新日期：2010-01-01 00:00:00

abstract：:Breast fed infants may be at greater risk of mother to infant hepatitis B virus infection compared with formula fed infants. We studied 85 infants born to 84 hepatitis B surface antigen positive mothers (only two of whom were hepatitis B e positive), and who had received immunisation against hepatitis B virus. Our res...

journal_title：Archives of disease in childhood

authors： de Martino M,Appendino C,Resti M,Rossi ME,Muccioli AT,Vierucci A

更新日期：1985-10-01 00:00:00

abstract：:The communication development in 11 children with Angelman's syndrome is described. The clinical observation that these children appear to have a greater ability with receptive rather than expressive language is investigated and these skills assessed using published communication schedules. In addition the understandi...

journal_title：Archives of disease in childhood

authors： Jolleff N,Ryan MM

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:Assays based on interferon gamma (IFNgamma) are an exciting new development for screening for latent tuberculosis infection (LTBI) in adults, but there are limited data on their effectiveness in children. Nevertheless new National Institute for Health and Clinical Excellence (NICE) guidelines recommend their ...

journal_title：Archives of disease in childhood

authors： Taylor RE,Cant AJ,Clark JE

更新日期：2008-03-01 00:00:00

abstract：:Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature. Although antipyretic drugs are the main form of treatment, this report considers the part that physical treatments might play in reducing the temperature of febrile children. Such treatments i...

journal_title：Archives of disease in childhood

authors： Purssell E

更新日期：2000-03-01 00:00:00

abstract：:At the Birmingham Maternity Hospital the mean cost of caring for surviving infants who require neonatal intensive care ranges from approximately pounds 2500 (for infants above 1500 g birthweight), to pounds 5500 (for infants 1000 to 1499 g birthweight), to pounds 10 000 (for infants less than 1000 g birthweight). The ...

journal_title：Archives of disease in childhood

authors： Newns B,Drummond MF,Durbin GM,Culley P

更新日期：1984-11-01 00:00:00

abstract：:Hepatitis B virus infection is still a major public health problem worldwide, since more than 350 million people have chronic, lifelong infection and nearly 1 million deaths occur each year owing to complications. Most infections are acquired at birth or during early childhood. Nowadays, low- and middle-income countri...

journal_title：Archives of disease in childhood

authors： Nannini P,Sokal EM

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:To determine the incidence of insulin dependent diabetes mellitus (IDDM) among children aged up to 16 years residing in the city of Karachi, Pakistan, during the five years from 1989 to 1993. DESIGN:Retrospective study of incidence using hospital and clinic records. SETTING:The city of Karachi, Pakistan. ...

journal_title：Archives of disease in childhood

authors： Staines A,Hanif S,Ahmed S,McKinney PA,Shera S,Bodansky HJ

更新日期：1997-02-01 00:00:00

abstract：:Urinary lithogenic and inhibitory factors were studied in 27 preterm infants; 16 had total parenteral nutrition (TPN) and 11 had breastmilk with an additional glucose-sodium chloride infusion. Urines were collected for 24 hours on day 2 (period A), day 3 (B), and once between days 4 and 10 (C). Urinary calcium oxalate...

journal_title：Archives of disease in childhood

authors： Hoppe B,Hesse A,Neuhaus T,Fanconi S,Forster I,Blau N,Leumann E

更新日期：1993-09-01 00:00:00

abstract：AIM:To determine the frequency of use of complementary treatment and measure its impact on clinical outcomes in a hospitalised general paediatric population. METHODS:A population based random sample of children admitted to the general paediatric service at a metropolitan children's hospital in Auckland, New Zealand fr...

journal_title：Archives of disease in childhood

authors： Armishaw J,Grant CC

更新日期：1999-08-01 00:00:00

abstract：:We have studied 50 children with one parent with asthma at a mean age of 6.4 years by symptom questionnaire and performed allergy skin testing and measurement of bronchial responsiveness to methacholine in both parent and child in 29-32 cases. Ninety eight per cent of the parents were receiving medication for asthma. ...

journal_title：Archives of disease in childhood

authors： Clifford RD,Pugsley A,Radford M,Holgate ST

更新日期：1987-01-01 00:00:00

abstract：:A preterm infant with classic phenylketonuria required rather less than 90 mg/kg of phenylalanine and between 270 and 290 mg/kg tyrosine daily to achieve a rate of weight gain of around 20 g/kg per day. Using Lofenalac as the low phenylalanine food, the intake of tyrosine, an essential amino acid for patients with phe...

journal_title：Archives of disease in childhood

authors： Shortland D,Smith I,Francis DE,Ersser R,Wolff OH

更新日期：1985-03-01 00:00:00

abstract：:Fifty nine children of short stature exercised for 10 minutes on a non-motorised treadmill. In 49 a growth hormone concentration of greater than 15 mU/l was reached, effectively excluding growth hormone deficiency. In 10 children the growth hormone concentration failed to reach 15 mU/l; growth hormone deficiency was c...

journal_title：Archives of disease in childhood

authors： de San Lazaro C,Parkin JM,Turner SJ

更新日期：1984-12-01 00:00:00

abstract：:Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it m...

journal_title：Archives of disease in childhood

authors： James WH

更新日期：1980-04-01 00:00:00

abstract：OBJECTIVE:To investigate whether school readiness could be affected by placing electronic devices (EDs) in children's bedroom and whether the relationship was moderated by parental restriction and family socioeconomic status (SES). DESIGN:This is a cross-sectional study with bedroom ED placement and parental restricti...

journal_title：Archives of disease in childhood

authors： Fu KW,Ho FKW,Rao N,Jiang F,Li SL,Lee TM,Chan SH,Yung AW,Young ME,Ip P

更新日期：2017-12-01 00:00:00