Hepatitis B: changing epidemiology and interventions.

Abstract:

:Hepatitis B virus infection is still a major public health problem worldwide, since more than 350 million people have chronic, lifelong infection and nearly 1 million deaths occur each year owing to complications. Most infections are acquired at birth or during early childhood. Nowadays, low- and middle-income countries bear the majority of the burden of hepatitis B-related liver cancer deaths despite the availability of an effective vaccine and antiviral treatments. In this review the epidemiology, strategies of prevention and the recent advances in therapy, genotype diversity and resistance are discussed.

journal_name

Arch Dis Child

authors

Nannini P,Sokal EM

doi

10.1136/archdischild-2016-312043

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

676-680

issue

7

eissn

0003-9888

issn

1468-2044

pii

archdischild-2016-312043

journal_volume

102

pub_type

杂志文章,评审
  • Plethysmographic validation of near infrared spectroscopic monitoring of cerebral blood volume.

    abstract::The validation of measurement of cerebral blood volume (CBV) and cerebral blood flow (CBF) using near infrared spectroscopy (NIRS) against jugular venous occlusion plethysmography is described. Repeated measurements in six infants were made using both techniques simultaneously. A close relationship between the two mea...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.4_spec_no.407

    authors: Wickramasinghe YA,Livera LN,Spencer SA,Rolfe P,Thorniley MS

    更新日期:1992-04-01 00:00:00

  • Comparative growth of primary schoolchildren from one and two parent families.

    abstract::Data drawn from the National Study of Health and Growth enabled an examination to be made of the attained height, weight for height, and triceps skinfold of children from one and two parent families. Children from one parent families were shorter than children from two parent families; however, once heights had been a...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.57.6.453

    authors: Garman AR,Chinn S,Rona RJ

    更新日期:1982-06-01 00:00:00

  • Retrospective review of Synacthen testing in infants.

    abstract:BACKGROUND:A subnormal cortisol response (30 min level (C30min)<550 nmol/L) to synthetic adrenocorticotrophic hormone/Synacthen test (SDST) in all infants does not necessarily indicate underlying or persistent hypothalamic-pituitary-adrenal axis pathology. METHODS:We retrospectively evaluated the diagnoses and outcome...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2017-313819

    authors: Tan TSE,Manfredonia C,Kumar R,Jones J,O'Shea E,Padidela R,Skae M,Ehtisham S,Ivison F,Tetlow L,Clayton PE,Banerjee I,Patel L

    更新日期:2018-10-01 00:00:00

  • When home is where the stress is: expanding the dimensions of housing that influence asthma morbidity.

    abstract::The influence of physical housing quality on childhood asthma expression, especially the effect of exposure to moulds, allergens, and pollutants, is well documented. However, attempts to explain increasing rates and severity of childhood asthma solely through physical environmental factors have been unsuccessful, and ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2006.098376

    authors: Sandel M,Wright RJ

    更新日期:2006-11-01 00:00:00

  • Congenital haemolytic anaemia associated with abnormal inducible red cell cation permeability.

    abstract::Congenital haemolytic anaemia in a 14 year old girl was caused by increased red cell membrane cation permeability. Potassium permeability was unusually sensitive to hydrostatic pressure and treatment with N-ethylmaleimide, factors which activate a specific chloride dependent potassium channel in cell membranes. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.58.7.547

    authors: Gardiner RM,Barnes ND,Ellory JC

    更新日期:1983-07-01 00:00:00

  • Ultrafiltration for intractable ascites after liver transplantation.

    abstract::A 5.7 year old boy with alpha 1-antitrypsin deficiency developed intractable ascites after liver transplantation. Conservative treatment was unsuccessful and after 18 days concentrated ascitic fluid was reinfused intravenously using a Gambro haemofilter. The ascitic loss resolved rapidly. This new method of ultrafiltr...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.8.988

    authors: Noble-Jamieson G,Jamieson N,Barnes ND

    更新日期:1991-08-01 00:00:00

  • Syncope in childhood.

    abstract::Syncope in childhood is very common. The vast majority of episodes are benign, and are due to neurocardiogenic syncope. Only a minority are due to something potentially more serious or life threatening. The diagnosis and differentiation of benign from more serious causes of syncope is made primarily by the history. In...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.88.4.350

    authors: McLeod KA

    更新日期:2003-04-01 00:00:00

  • Hepatopathy of Mauriac syndrome: a retrospective review from a tertiary liver centre.

    abstract:BACKGROUND:Mauriac syndrome is characterised by growth failure, cushingoid appearance and hepatomegaly which occurs in patients with insulin dependent diabetes and was first described shortly after the introduction of insulin as a treatment for the condition. OBJECTIVE:To describe the clinical features, histological f...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2013-304426

    authors: Fitzpatrick E,Cotoi C,Quaglia A,Sakellariou S,Ford-Adams ME,Hadzic N

    更新日期:2014-04-01 00:00:00

  • Diagnosis of primary human herpesvirus 6 and 7 infections in febrile infants by polymerase chain reaction.

    abstract::Primary human herpesvirus 6 (HHV-6) and 7 (HHV-7) infections were identified in febrile children by qualitative and quantitative polymerase chain reaction (PCR) assays. Diagnosis was based on the differential detection of viral DNA in peripheral blood mononuclear cells (PBMC), but not in saliva. Six of 41 febrile infa...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.77.1.42

    authors: Clark DA,Kidd IM,Collingham KE,Tarlow M,Ayeni T,Riordan A,Griffiths PD,Emery VC,Pillay D

    更新日期:1997-07-01 00:00:00

  • Familial partial trisomy of the long arm of chromosome 3 (3q).

    abstract::A case of partial trisomy of the long arm of chromosome 3 (3q21 leads to qter) is described. The clinical findings are compared with those in 5 previously reported cases. There is hirsutism and characteristic facial dysmorphism, the common features of which are a square-shaped face, prominent nasal bridge, everted nos...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.54.2.135

    authors: Fear C,Briggs A

    更新日期:1979-02-01 00:00:00

  • Life expectancy in severe cerebral palsy.

    abstract::Cerebral palsy comprises an important component of paediatric and obstetric practice and has major medico-legal implications. The prognosis for survival in cerebral palsy determines the financial provision made in cases that come to litigation. Issues of data quality and estimation methods are critical. Estimating the...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2005.075002

    authors: Hutton JL,Pharoah PO

    更新日期:2006-03-01 00:00:00

  • Pubertal stage and hypoglycaemia counterregulation in type 1 diabetes.

    abstract:AIMS:To compare physiological and autonomic responses to acute hypoglycaemia in diabetic children in pre-, mid-, and post-pubertal stages of development. METHODS:Twenty seven children (8 pre-pubertal, 7 mid-pubertal, 12 post-pubertal) with type 1 diabetes were studied. Hypoglycaemia was induced by insulin infusion unt...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2004.052035

    authors: Ross LA,Warren RE,Kelnar CJ,Frier BM

    更新日期:2005-02-01 00:00:00

  • Arthritis in children: comparison of clinical and biological characteristics of septic arthritis and juvenile idiopathic arthritis.

    abstract:AIM:Childhood arthritis arises from several causes. The aim of this observational study is to compare the clinical and biological features and short-term outcome of different types of arthritis because they have different treatment and prognoses. METHODS:Children <16 years of age hospitalised in a French tertiary care...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/archdischild-2016-310594

    authors: Aupiais C,Basmaci R,Ilharreborde B,Blachier A,Desmarest M,Job-Deslandre C,Faye A,Bonacorsi S,Alberti C,Lorrot M

    更新日期:2017-04-01 00:00:00

  • Angioplasty for renovascular hypertension in 78 children.

    abstract:OBJECTIVES:To evaluate the outcome of percutaneous transluminal angioplasty (PTA) in children with renovascular hypertension (RVH) treated at a single centre over 29 years. METHODS:A retrospective study of the medical charts of all children with RVH who underwent PTA between 1984 and 2012. The primary outcome measurem...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2013-305886

    authors: Kari JA,Roebuck DJ,McLaren CA,Davis M,Dillon MJ,Hamilton G,Shroff R,Marks SD,Tullus K

    更新日期:2015-05-01 00:00:00

  • USE OF PILL GLIDE TO ENCOURAGE TRANSITION FROM LIQUID TO SOLID DOSAGE FORMULATIONS.

    abstract:SITUATION:Patient I is a 15 year old female with ornithine transcarbamylase deficiency prescribed L-arginine 1.5 g three times daily and sodium benzoate 4.2 g three times daily. By taking her medication and controlling her diet she is able to lead a normal life and does well at school. However she struggles with the pa...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2016-311535.8

    authors: Gaskell C

    更新日期:2016-09-01 00:00:00

  • Age specific xerophthalmia rates among displaced Ethiopians.

    abstract::The recent famine in Ethiopia has resulted in the dislocation of millions of people. Many of these individuals have moved to refugee camps in Sudan or to feeding centres within Ethiopia. A total of 1325 children up to the age of 15 years were examined by an ophthalmologist in January 1985 at several sites in these two...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.11.1100

    authors: Pizzarello LD

    更新日期:1986-11-01 00:00:00

  • Childhood and adolescent mental health of NICU graduates: an observational study.

    abstract:OBJECTIVE:To investigate the mental health of children and adolescents admitted to neonatal intensive/special care units (NICUs) in infancy. METHODS:This cross-sectional study used a provincially representative cohort from the 2014 Ontario Child Health Study. Parents provided data on psychiatric disorders using the MI...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2019-318284

    authors: Chiorean A,Savoy C,Beattie K,El Helou S,Silmi M,Van Lieshout RJ

    更新日期:2020-07-01 00:00:00

  • The importance of reverse triiodothyronine in hypothyroid children on replacement treatment.

    abstract::Reverse triiodothyronine (rT3), triiodothyronine (T3), thyroxine (T4), and thyroid stimulating hormone (TSH) values were measured by radioimmunoassay in 40 children with congenital hypothyroidism who were being given levothyroxine (0.05-0.35 mg/day) and in 14 normal controls. In 15 of the children with hypothyroidism ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.59.1.30

    authors: Desai M,Irani AJ,Patil K,Pandya CS

    更新日期:1984-01-01 00:00:00

  • Improved outcome of acute myeloid leukaemia in Down's syndrome.

    abstract:OBJECTIVE:To review the clinical features, treatment, and outcome of children in the UK with Down's syndrome and acute myeloid leukaemia (AML). DESIGN:A retrospective study of 59 children with Down's syndrome and AML presenting between 1987 and 1995. Data were obtained from hospital case notes, trial records, and by q...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.81.1.32

    authors: Craze JL,Harrison G,Wheatley K,Hann IM,Chessells JM

    更新日期:1999-07-01 00:00:00

  • Pneumococcal nasopharyngeal carriage in children following heptavalent pneumococcal conjugate vaccination in infancy.

    abstract:AIMS:To ascertain whether the reduction in nasopharyngeal carriage of vaccine serotypes induced by pneumococcal conjugate vaccine (PnCV) administered to infants persists beyond the age of 2 years. METHODS:Non-randomised, unblinded controlled study of 2-5 year old children who had received three doses of heptavalent Pn...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章

    doi:10.1136/adc.88.3.211

    authors: Lakshman R,Murdoch C,Race G,Burkinshaw R,Shaw L,Finn A

    更新日期:2003-03-01 00:00:00

  • Randomised double blind placebo controlled trial of the effect of botulinum toxin on walking in cerebral palsy.

    abstract:BACKGROUND:Cerebral palsy is the commonest cause of severe physical disability in childhood. For many years treatment has centred on the use of physiotherapy and orthotics to overcome the problems of leg spasticity, which interferes with walking and can lead to limb deformity. Intramuscular botulinum toxin (BT-A) offer...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/adc.83.6.481

    authors: Ubhi T,Bhakta BB,Ives HL,Allgar V,Roussounis SH

    更新日期:2000-12-01 00:00:00

  • Prophylactic antibiotics in umbilical artery catheterization in the newborn.

    abstract::Over a period of 30 months, umbilical artery catheters were inserted in 229 infants. The main complications were haemorrhage, infection, and obstruction of a blood vessel. The incidence of infection was not affected by the use of prophylactic antibiotics. Vascular obstruction was more common in small infants, and in t...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.48.4.296

    authors: van Vliet PK,Gupta JM

    更新日期:1973-04-01 00:00:00

  • Certified cause of death in children and young adults with cerebral palsy.

    abstract::The status of 732 children suffering from cerebral palsy from the South East Thames region (births from 1970-9) was ascertained at the end of 1989, and copies of death certificates of the 73 children who have died, aged 4 weeks to nearly 16 years, were obtained. Infantile cerebral palsy (ICD Code 343-) was coded as th...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.3.325

    authors: Evans PM,Alberman E

    更新日期:1991-03-01 00:00:00

  • Natural history of trisomy 13.

    abstract::The poor prognosis of patients with trisomy 13 has long been accepted and has been ascribed to brain and heart malformations. It has been suggested, however, that the long term survival is better than was previously thought and that cardiac surgery may be justified. This population based study reviews the incidence, a...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.71.4.343

    authors: Wyllie JP,Wright MJ,Burn J,Hunter S

    更新日期:1994-10-01 00:00:00

  • Educational attainment in childhood cancer survivors: a meta-analysis.

    abstract:OBJECTIVE:To assess differences across educational outcomes in survivors of childhood cancer (CCS) compared with peers. DESIGN:Systematic review and meta-analysis of observational studies. DATA SOURCES AND STUDY SELECTION:Medline, EMBASE, ERIC, CINAHL and PsycInfo from inception to 1st August 2018. Any peer reviewed,...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/archdischild-2019-317594

    authors: Saatci D,Thomas A,Botting B,Sutcliffe AG

    更新日期:2020-04-01 00:00:00

  • Small bowel biopsy.

    abstract::We describe our technique of small bowel biopsy, which has been used on 190 occasions over a four year period. In 77%, the examination was completed within 10 minutes, and fluoroscopy times were less than 10 seconds in 75% of the cases. The technique is easily taught, and it has made the examination a minor procedure....

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.60.11.1082

    authors: Collins AL,Brookfield DS,Hyde I,Rolles CJ

    更新日期:1985-11-01 00:00:00

  • Ultrasonic assessment of gastric emptying in the preterm infant.

    abstract::The study of gastric emptying in the preterm infant has been hampered by the absence of a suitable, valid technique. We have evaluated gastric antral clearance using serial ultrasonic measurement of the antral cross sectional area (ACSA). The study was easy to perform, providing successful results in 15 of 17 low birt...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.69.1_spec_no.32

    authors: Newell SJ,Chapman S,Booth IW

    更新日期:1993-07-01 00:00:00

  • A polymorph bactericidal defect and a lupus-like syndrome.

    abstract::We describe a child with primary defect of polymorph bacterial killing associated with systemic lungs erythematosus. We suggest that her autoimmune disease results from chronic bacterial antigen stimulation and propose a hypothetical model linking immunodeficiency with autoimmunity. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.56.5.382

    authors: Levinsky RJ,Harvey BA,Roberton DM,Wolff OH

    更新日期:1981-05-01 00:00:00

  • Immunological responses to respiratory syncytial virus infection in infancy.

    abstract:OBJECTIVES:To determine whether there is evidence of immunological responses in infants with respiratory syncytial virus (RSV) bronchiolitis by measuring inflammatory mediators in peripheral blood and, if found, whether these related to the severity of illness. PATIENTS AND METHODS:Blood was taken from 94 children wit...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.76.3.210

    authors: Smyth RL,Fletcher JN,Thomas HM,Hart CA

    更新日期:1997-03-01 00:00:00

  • Cigarette smoking among secondary schoolchildren 1975-79.

    abstract::A questionnaire relating to smoking habits, respiratory symptoms, and health attitude was administered to schoolchildren aged between 11 and 17 throughout a defined geographical area in both 1975 and 1979, with a valid response from 10498 and 12002 young people respectively. Each cohort was almost entirely different. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.57.5.352

    authors: Rawbone RG,Guz A

    更新日期:1982-05-01 00:00:00