Abstract:
AIM:Childhood arthritis arises from several causes. The aim of this observational study is to compare the clinical and biological features and short-term outcome of different types of arthritis because they have different treatment and prognoses. METHODS:Children <16 years of age hospitalised in a French tertiary care centre for a first episode of arthritis lasting for less than 6 weeks who underwent joint aspiration were retrospectively included. We performed non-parametrical tests to compare groups (septic arthritis (SA), juvenile idiopathic arthritis (JIA) and arthritis with no definitive diagnosis). The time before apyrexia or C reactive protein (CRP) <10 mg/L was analysed using the Kaplan-Meier method. RESULTS:We studied 125 children with a sex ratio (M/F) of 1.1 and a median age of 2.2 years (range 0.3 to 14.6). SA was associated with a lower age at onset (1.5 years, IQR 1.2-3.0 vs 3.6 years, IQR 2.2-5.6), shorter duration of symptoms before diagnosis (2 days, IQR 1-4 vs 7 days, IQR 1-19) and higher synovial white blood cell count (147 cells ×103/mm3, IQR 71-227, vs 51 cells ×103/mm3, IQR 12-113), than JIA. Apyrexia occurred later in children with JIA (40% after 2 days, 95% CI 17% to 75%) than children with SA (82%, 95% CI 68% to 92%), as did CRP<10 mg/L (18% at 7 days, 95% CI 6.3% to 29.6% vs 82.1%, 95% CI 76.1% to 89.7%, p=0.01). CONCLUSIONS:There were no sufficiently reliable predictors for differentiating between SA and JIA at onset. The outcomes were different; JIA should be considered in cases of poor disease evolution after antibiotic treatment and joint aspiration.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Aupiais C,Basmaci R,Ilharreborde B,Blachier A,Desmarest M,Job-Deslandre C,Faye A,Bonacorsi S,Alberti C,Lorrot Mdoi
10.1136/archdischild-2016-310594subject
Has Abstractpub_date
2017-04-01 00:00:00pages
316-322issue
4eissn
0003-9888issn
1468-2044pii
archdischild-2016-310594journal_volume
102pub_type
杂志文章,多中心研究abstract:OBJECTIVE:To compare a comprehensive lifestyle intervention for overweight children performed in groups of families with a conventional single-family treatment. Two-year follow-up data on anthropometric and psychological outcome are presented. DESIGN:Overweight and obese children aged 6-12 years with body mass index (...
journal_title:Archives of disease in childhood
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abstract:BACKGROUND AND AIMS:Following recent reports of increased numbers of adolescents being diagnosed with the adult or type 2 form of diabetes we aimed to describe the prevalence of both type 2 and other forms of diabetes in an urban population of children and young people in northern England. METHODS:A hospital based cro...
journal_title:Archives of disease in childhood
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journal_title:Archives of disease in childhood
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abstract::The introduction of enteric coated pancreatic enzyme supplements in the early 1980s was undoubtedly one of the major advances in the care of children with cystic fibrosis. Further refinements in the presentation of these preparations inevitably followed, to improve patient acceptability and compliance. The emergence o...
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abstract::The fall in body temperature that occurs in babies soon after birth is influenced by the baby's weight and its environmental conditions. The rate of oxygen consumption 1 1/2 hours after birth was unrelated to body temperature and only slightly raised, indicating a limited thermogenic capacity. A radiant heater effecti...
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journal_title:Archives of disease in childhood
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journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
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journal_title:Archives of disease in childhood
pub_type: 杂志文章,随机对照试验
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journal_title:Archives of disease in childhood
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journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2007-09-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2006-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:1980-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:1992-03-01 00:00:00