A polymorph bactericidal defect and a lupus-like syndrome.

abstract：:Four patients with salt-losing congenital adrenal hyperplasia (CAH) who had stopped mineralocorticoid therapy for several years, showed raised plasma concentrations of 17OH-progesterone and plasma renin activity, despite adequate glucoticoid therapy. One patient was able to reduce urinary sodium excretion when the sod...

journal_title：Archives of disease in childhood

authors： Hughes IA,Wilton A,Lole CA,Gray OP

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To examine the risk of disability from unintentional injury in teenagers and young adults. METHODS:Analyses of data from the National Child Development Study, a follow up study of 98% of all children born in England, Scotland, and Wales in one week in March, 1958. In 1981, 12,537 study participants, 76% of t...

journal_title：Archives of disease in childhood

authors： Barker M,Power C,Roberts I

更新日期：1996-08-01 00:00:00

abstract：:Multiple double blind placebo controlled challenges with tartrazine 50 mg (three challenges) and glucose placebo (three challenges) were performed in 12 children with atopic eczema aged 1 to 6 years. The children were selected on the basis of severity (regular clinic attenders) and a parental history that tartrazine p...

journal_title：Archives of disease in childhood

authors： Devlin J,David TJ

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To examine the prevalence of dysnatraemias among children admitted for paediatric surgery before and after a change from hypotonic to isotonic intravenous maintenance fluid therapy. DESIGN:Retrospective consecutive time series intervention study. SETTING:Paediatric surgery ward at the Children's Hospital in...

journal_title：Archives of disease in childhood

authors： Chromek M,Jungner Å,Rudolfson N,Ley D,Bockenhauer D,Hagander L

更新日期：2020-10-28 00:00:00

abstract：:A 3 year old girl with Down's syndrome became lethargic and withdrawn, and investigations showed a specific malabsorption of vitamin B12 without proteinuria. ...

journal_title：Archives of disease in childhood

authors： Cartlidge PH,Curnock DA

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVE:To develop a clinical algorithm to identify paediatric patients who should be offered HIV testing in a setting of moderate HIV prevalence and limited resources. METHODS:In a prospective cross-sectional study at Port Moresby General Hospital, Papua New Guinea, carers of inpatients were offered HIV testing and...

journal_title：Archives of disease in childhood

authors： Allison WE,Kiromat M,Vince J,Wand H,Cunningham P,Graham SM,Kaldor J

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:To determine if there had been changes in the size of the UK paediatric workforce and working patterns between 1999 and 2013. DESIGN:Analysis of prospectively collected datasets. SETTING:UK consultant paediatricians. INTERVENTIONS:Data from the Royal College of Paediatrics and Child Health's workforce cen...

journal_title：Archives of disease in childhood

authors： McColgan M,Winch R,Clark SJ,Ewing C,Modi N,Greenough A

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Silver-Russell syndrome (SRS) is an imprinted disorder characterised by intrauterine growth retardation, relative macrocephaly, failure to thrive, typical facial phenotype and frequent body asymmetry. Feeding difficulties are frequently noted, but no study described evolution of gastrointestinal signs during...

journal_title：Archives of disease in childhood

authors： Marsaud C,Rossignol S,Tounian P,Netchine I,Dubern B

更新日期：2015-04-01 00:00:00

abstract：:Life was sorted. With membership of the college under my belt, and my paediatric training completed, I needed a new challenge. I decided to launch into the deep waters of qualitative research. Stepping out with some trepidation into semistructured interviews and grounded theory, I soon found that the water was neither...

journal_title：Archives of disease in childhood

authors： Sidebotham P

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Due to lack of information on drug use in children, many drugs are used off-label in paediatrics. Increased knowledge of adverse drug reactions (ADRs) would enable a better risk-benefit analysis. Our aim was to characterise drugs causing psychiatric ADRs in children by conducting a descriptive study based on ...

journal_title：Archives of disease in childhood

authors： Ekhart C,Vries T,Hunsel FV

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Cochlear implantation in one ear (unilateral implantation) has been the standard treatment for severe-profound childhood deafness. We assessed whether cochlear implantation in both ears (bilateral implantation) is associated with better listening skills, higher health-related quality of life (health utility) ...

journal_title：Archives of disease in childhood

authors： Lovett RE,Kitterick PT,Hewitt CE,Summerfield AQ

更新日期：2010-02-01 00:00:00

abstract：:Metabolic rhythms were studied over 24 hours in eight adolescent diabetic patients during treatment with porcine insulin and after transfer to human insulin. Despite an increase in dose with human insulin no significant changes were found in fasting blood glucose, 24h mean blood glucose, or glycosylated haemoglobin co...

journal_title：Archives of disease in childhood

authors： Hocking MD,Crase J,Rayner PH,Nattrass M

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:Assays based on interferon gamma (IFNgamma) are an exciting new development for screening for latent tuberculosis infection (LTBI) in adults, but there are limited data on their effectiveness in children. Nevertheless new National Institute for Health and Clinical Excellence (NICE) guidelines recommend their ...

journal_title：Archives of disease in childhood

authors： Taylor RE,Cant AJ,Clark JE

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIMS:There are few standardised questionnaires for the assessment of respiratory symptoms in preschool children. We have developed and tested the short-term repeatability of a postal questionnaire on respiratory symptoms for 1-year-old children. METHODS:A newly developed postal questionnaire for the ass...

journal_title：Archives of disease in childhood

authors： Strippoli MP,Silverman M,Michel G,Kuehni CE

更新日期：2007-10-01 00:00:00

abstract：:The effect of raising the airways resistance of 56 normal newborn babies by blocking alternate nostrils was studied by means of oesophageal intubation and the trunk plethysmograph. Increased resistance was associated with reduced respiratory rate and ventilation. A comparison was made of the response in different slee...

journal_title：Archives of disease in childhood

authors： Purcell M

更新日期：1976-08-01 00:00:00

abstract：:Therapeutic drug monitoring (TDM) aims to integrate drug measurement results into clinical decision making. The basic rules apply when using TDM in neonates (aminoglycosides, vancomycin, phenobarbital, digoxin), but additional factors should also be taken into account. First, due to both pharmacokinetic variability an...

journal_title：Archives of disease in childhood

authors： Pauwels S,Allegaert K

更新日期：2016-04-01 00:00:00

abstract：:The contribution of abnormal cardiac function to hypotension and metabolic acidosis, which affect approximately 40% of ventilated very low birthweight infants in the first 24 hours after birth was assessed using M mode, two dimensional, and Doppler echocardiography in 75 very low birthweight infants during the first f...

journal_title：Archives of disease in childhood

authors： Gill AB,Weindling AM

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of adenoidectomy, a frequent operation during childhood, is unknown. Therefore, the role of adenoidectomy in the development of atop...

journal_title：Archives of disease in childhood

authors： Mattila PS,Hammarén-Malmi S,Pelkonen AS,Malmberg LP,Mäkelä MJ,Saxen H,Tarkkanen J

更新日期：2009-05-01 00:00:00

abstract：:Over a period of 30 months, umbilical artery catheters were inserted in 229 infants. The main complications were haemorrhage, infection, and obstruction of a blood vessel. The incidence of infection was not affected by the use of prophylactic antibiotics. Vascular obstruction was more common in small infants, and in t...

journal_title：Archives of disease in childhood

authors： van Vliet PK,Gupta JM

更新日期：1973-04-01 00:00:00

abstract：BACKGROUND:The number of trips to the tropics taken by children with chronic health disorders (CHDs) is increasing. METHODS:All of the children with CHDs who attended two international vaccination centres in France before travelling to the tropics were included in a prospective, exposed/unexposed study. Each child was...

journal_title：Archives of disease in childhood

authors： Ducrocq C,Sommet J,Levy D,Trieu TV,Quercia F,Morin L,Belletre X,Koehl B,Sorge F,Alberti C,de Pontual L,Faye A

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Mauriac syndrome is characterised by growth failure, cushingoid appearance and hepatomegaly which occurs in patients with insulin dependent diabetes and was first described shortly after the introduction of insulin as a treatment for the condition. OBJECTIVE:To describe the clinical features, histological f...

journal_title：Archives of disease in childhood

authors： Fitzpatrick E,Cotoi C,Quaglia A,Sakellariou S,Ford-Adams ME,Hadzic N

更新日期：2014-04-01 00:00:00

abstract：:Retrospective analysis of glycosylated haemoglobin concentrations in a diabetic outpatient clinic over three and a half years showed a small seasonal variation in the mean value with a peak in mid February and a nadir in mid August. ...

journal_title：Archives of disease in childhood

authors： Ferrie CD,Sharpe TC,Price DA,Surtees RA

更新日期：1987-09-01 00:00:00

abstract：:The concentration of zinc in the hair of 219 schoolchildren aged between 10 and 11 years was measured and related to height, weight, estimates of consumption of zinc-rich foods, number of children living at home, and rank in family. None of the correlation coefficients between hair zinc and the other variables was sig...

journal_title：Archives of disease in childhood

authors： Heinersdorff N,Taylor TG

更新日期：1979-12-01 00:00:00

abstract：:Two male patients with congenital cleft lip and palate first seen at ages 10.2 and 21.5 years presented with typical signs of hypothalamic-interior pituitary hormone deficiencies. They were found to lack GH, LH, and FSH and to be partially deficient in TSH and ACTH. Several congenital defects may explain this rare syn...

journal_title：Archives of disease in childhood

authors： Roitman A,Laron Z

更新日期：1978-12-01 00:00:00

abstract：OBJECTIVES:To establish the incidence of childhood coeliac disease (CD) in Scotland between 1 September 2009 and 31 August 2010, to determine clinical features at presentation and reasons for diagnosis, and to identify any differences in incidence and practice between regions. DESIGN:Prospective data collection throug...

journal_title：Archives of disease in childhood

authors： White LE,Bannerman E,McGrogan P,Kastner-Cole D,Carnegie E,Gillett PM

更新日期：2013-01-01 00:00:00

abstract：:Quantitative biochemical criteria for lung growth and maturation were compared with the histological appearances in hypoplastic lungs from 20 fetuses and newborn infants. Cases associated with oligohydramnios showed a characteristic series of changes with narrow airways, retardation of epithelial and interstitial grow...

journal_title：Archives of disease in childhood

authors： Wigglesworth JS,Desai R,Guerrini P

更新日期：1981-08-01 00:00:00

abstract：:There may be insufficient awareness of dopa responsive dystonia (DRD), which has a characteristic diurnal variation of symptoms. Two children are reported in whom the diagnosis of DRD was missed. The first was thought to have hysteria and the second hereditary spastic paraparesis. A full history is vital for the diagn...

journal_title：Archives of disease in childhood

authors： Patel K,Roskrow T,Davis JS,Heckmatt JZ

更新日期：1995-09-01 00:00:00

abstract：:Serial recording in 45 low risk fetuses throughout the second and third trimesters showed that hiccups were the predominant diaphragmatic movement before 26 weeks' gestational age and that there was a significant negative correlation with gestational age. There was a pronounced reduction between 24 and 26 weeks, which...

journal_title：Archives of disease in childhood

authors： Pillai M,James D

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:The prevalence of thyroid disease is increased in Down's syndrome. Most available data come from cross sectional studies. AIMS:To study longitudinally thyroid function in patients with Down's syndrome in Uppsala county (85 patients) up to the age of 25 years. METHODS:Observational study based on yearly fol...

journal_title：Archives of disease in childhood

authors： Karlsson B,Gustafsson J,Hedov G,Ivarsson SA,Annerén G

更新日期：1998-09-01 00:00:00

abstract：:Two neonates with spontaneous rupture of the bladder and an otherwise normal genitourinary tract are described. Conservative management resulted in complete resolution of the lesion in one but the other child died from a coliform septicaemia. Necropsy showed a discrete ischaemic lesion in the fundus of the bladder. ...

journal_title：Archives of disease in childhood

authors： Morrell P,Coulthard MG,Hey EN

更新日期：1985-07-01 00:00:00