Therapeutic drug monitoring in neonates.

abstract：:The incidence of minor congenital anomalies was examined in 36 patients with ataxic cerebral palsy, in unaffected family members, and in 100 unrelated control subjects. None of the control subjects or family members had more than four anomalies, and 25 of 36 (69%) of the patients had more than four. The distribution o...

journal_title：Archives of disease in childhood

authors： Miller G

更新日期：1989-04-01 00:00:00

abstract：:In depth confidential inquiries on all post-perinatal infant deaths were carried out for two years in North and Southern Derbyshire District Health Authorities in order to explore why the postperinatal death rates and cot death rates have been consistently higher in Southern than in North Derbyshire. It was found that...

journal_title：Archives of disease in childhood

authors： Newlands M,Adamson E,Ghulam S,Saleh M,Emery JL

更新日期：1991-12-01 00:00:00

abstract：:Urinary tract anomalies were prospectively investigated with ultrasound in 29 children with functional constipation. These children were compared before and after treatment with 451 age matched healthy controls without constipation. The bladder residue and upper renal tract dilatation after micturition were significan...

journal_title：Archives of disease in childhood

authors： Dohil R,Roberts E,Jones KV,Jenkins HR

更新日期：1994-01-01 00:00:00

abstract：:The introduction of enteric coated pancreatic enzyme supplements in the early 1980s was undoubtedly one of the major advances in the care of children with cystic fibrosis. Further refinements in the presentation of these preparations inevitably followed, to improve patient acceptability and compliance. The emergence o...

journal_title：Archives of disease in childhood

authors： Smyth RL

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:Poor condition at birth may impact on IQ, although its effect on other measures of neurodevelopment is unclear. The authors' aim was to determine whether infants receiving resuscitation after birth have reduced scores in measures of attention, memory and language skills or the need for educational support at ...

journal_title：Archives of disease in childhood

authors： Odd DE,Whitelaw A,Gunnell D,Lewis G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Recent research in febrile neutropaenia (FN) has focused on reducing the intensity of treatment for those thought to be at low risk of significant morbidity or mortality. This has not led to a reduced burden of treatment for either families or healthcare systems. An alternative approach is to discharge all p...

journal_title：Archives of disease in childhood

authors： Seneviratne N,Yeomanson D,Phillips R

更新日期：2020-09-01 00:00:00

abstract：:Cystic fibrosis is a disease that still causes a reduced life expectancy. The treatment burden remains high for affected individuals with often a combination of multiple oral and inhaled medications, as well as physiotherapy, required on a daily basis. In this article, we look at an overview of the pathogenesis, how t...

journal_title：Archives of disease in childhood

authors： Davies JC,Ebdon AM,Orchard C

更新日期：2014-11-01 00:00:00

abstract：:Thirty six children with typical features of Angelman's syndrome, including global developmental delay, ataxia, episodes of paroxysmal laughter, seizures, and microcephaly were studied. The series included three sibships of three affected sisters, two affected brothers, and two affected sisters, respectively. The faci...

journal_title：Archives of disease in childhood

authors： Robb SA,Pohl KR,Baraitser M,Wilson J,Brett EM

更新日期：1989-01-01 00:00:00

abstract：:Three children with cystic fibrosis developed steatorrhoea unresponsive to changes in pancreatic supplements. The final diagnoses were chronic giardiasis, stagnant loop syndrome, and Crohn's disease. Refractory intestinal symptoms in cystic fibrosis merit further investigation. ...

journal_title：Archives of disease in childhood

authors： Baxter PS,Dickson JA,Variend S,Taylor CJ

更新日期：1988-12-01 00:00:00

abstract：:We have studied changes in the birthweight of Asian babies born alive at this hospital between 1968 and 1978. In 1978 Pakistani babies were 139 g heavier but Indian babies only 25 g heavier than 10 years earlier. Contributing to these changes were significantly fewer short mothers and primiparae among Pakistanis, and ...

journal_title：Archives of disease in childhood

authors： Clarson CL,Barker MJ,Marshall T,Wharton BA

更新日期：1982-11-01 00:00:00

abstract：AIM:To measure drug adherence in children with mild asthma receiving long term prophylactic treatment. METHODS:Double blind randomised placebo controlled trial. Patients received inhaled budesonide 100 microg or 200 microg daily, or placebo for 27 months. All participants were asked to inhale medication or placebo fro...

journal_title：Archives of disease in childhood

authors： Jónasson G,Carlsen KH,Mowinckel P

更新日期：2000-10-01 00:00:00

abstract：:In a multicentre study on perinatal HIV-I infection including 1493 children born from 1471 pregnancies to 1415 infected mothers, 22 twin pairs and 56 sibships (115 children) were recorded. The frequency of twin pregnancies was 1.5 (22/1471) and 3.9% (56/1415) seropositive women had more than one at risk pregnancy. In ...

journal_title：Archives of disease in childhood

authors： de Martino M,Tovo PA,Galli L,Caselli D,Gabiano C,Mazzoni PL,Giacomelli A,Duse M,Fundarò C

更新日期：1991-10-01 00:00:00

abstract：:We report two children with ruptured, multiple hydatid cysts treated with mebendazole. Long term follow up has confirmed the success of this treatment. ...

journal_title：Archives of disease in childhood

authors： Karpathios T,Syriopoulou V,Nicolaidou P,Messaritakis J

更新日期：1984-09-01 00:00:00

abstract：:Renal sodium handling was studied in 23 children at three different stages of the minimal change nephrotic syndrome--the oedema forming state, proteinuric steady state, and remission. Clearances of inulin and para-aminohippuric acid and urinary sodium excretion were determined basally, after intravenous infusion of is...

journal_title：Archives of disease in childhood

authors： Bohlin AB,Berg U

更新日期：1984-09-01 00:00:00

abstract：AIM:To explore the variation in hospital admission rates and duration of inpatient stay across England. METHODS:Hospital Episode Statistics were used to identify all children aged below 2 years who were discharged from hospital with a primary code of bronchiolitis in England, between 1 April 2007 and 31 March 2010; ra...

journal_title：Archives of disease in childhood

authors： Cheung CR,Smith H,Thurland K,Duncan H,Semple MG

更新日期：2013-01-01 00:00:00

abstract：:In 1973 a survey was conducted among 12 year old children living in a defined area of South Wales. In 1988 the survey was repeated in the same area, again among 12 year old children. Questionnaires were completed for all 965 children in the population sample; peak expiratory flow rates were performed on them all, and ...

journal_title：Archives of disease in childhood

authors： Burr ML,Butland BK,King S,Vaughan-Williams E

更新日期：1989-10-01 00:00:00

abstract：:Mild hypnotics are often recommended for young children with sleep problems. This study assesses the efficacy of trimeprazine tartrate in 1 to 3 year old children with persistent and severe night waking in a double blind crossover trial with placebo. Children on treatment with trimeprazine had significantly fewer waki...

journal_title：Archives of disease in childhood

authors： Simonoff EA,Stores G

更新日期：1987-03-01 00:00:00

abstract：:Diabetic control in 88 children attending three general paediatric clinics was compared prospectively over one year with that of 89 children attending a specialist paediatric diabetic clinic. Glycated haemoglobin (HbA1) concentration and days admitted were significantly lower in the group attending the specialist clin...

journal_title：Archives of disease in childhood

authors： Bloomfield S,Farquhar JW

更新日期：1990-01-01 00:00:00

abstract：:One hundred of the 192 survivors of repaired oesophageal atresia at the Royal Children's Hospital, Melbourne, aged one year and over on 1 November 1973, were reviewed to determine the frequency of respiratory complications. 78 children suffered from more than 3 attacks of bronchitis per year during the first 3 years o...

journal_title：Archives of disease in childhood

authors： Dudley NE,Phelan PD

更新日期：1976-04-01 00:00:00

abstract：:A randomised double blind, two period cross over study was designed to compare the ability of 51 hospitalised asthmatics with acute exacerbations to use each of two inhalers. The inhalers compared were a new breath actuated metered dose inhaler, the Autohaler inhalation device, and a dry powder device, the Rotahaler. ...

journal_title：Archives of disease in childhood

authors： Ruggins NR,Milner AD,Swarbrick A

更新日期：1993-04-01 00:00:00

abstract：:Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the age-appropriateness of the formulation. Generally, the younger the child, the more the attention that is required. For decades, there has been a general lack of (authorised) formulations ...

journal_title：Archives of disease in childhood

authors： van Riet-Nales DA,Schobben AF,Vromans H,Egberts TC,Rademaker CM

更新日期：2016-07-01 00:00:00

abstract：:The term Ehlers-Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many s...

journal_title：Archives of disease in childhood

authors： Sobey G

更新日期：2015-01-01 00:00:00

abstract：:A modified nasopharyngeal tube is described that does not add airway dead space and resistance, is well tolerated, highly successful, and allows simultaneous use of oxygen prongs. This potentially reduces the need for surgical intervention to relieve high upper airway obstruction from Pierre-Robin syndrome and other c...

journal_title：Archives of disease in childhood

authors： Masters IB,Chang AB,Harris M,O'Neil MC

更新日期：1999-02-01 00:00:00

abstract：:During a screening programme of 10000 pregnant women by the Guthrie test, a previously unrecognised phenylketonuric woman was detected. A low phenylalanine diet introduced from the 16th week of gestation failed to prevent fetal abnormality and mental retardation. Maternal phenylketonuria requires earlier diagnosis tha...

journal_title：Archives of disease in childhood

authors： Scott TM,Fyfe WM,Hart DM

更新日期：1980-08-01 00:00:00

abstract：:To determine the natural history and psychological impact of the growth pattern in boys with constitutional delay in growth and puberty (CDGP), 43 boys presenting with short stature due to CDGP were followed up to final height. At presentation mean (SD) chronological age was 14.0 (1.9) years, bone age delay 2.7 (1.0) ...

journal_title：Archives of disease in childhood

authors： Crowne EC,Shalet SM,Wallace WH,Eminson DM,Price DA

更新日期：1990-10-01 00:00:00

abstract：AIMS:To prospectively evaluate sinopulmonary disease in 24 patients with primary humoral immunodeficiency (11 with agammaglobulinaemia, nine with isolated IgA deficiency, and two with common variable immunodeficiency) and chronic productive cough, ascertain the usefulness of chest high resolution computed tomography (H...

journal_title：Archives of disease in childhood

authors： Rusconi F,Panisi C,Dellepiane RM,Cardinale F,Chini L,Martire B,Bonelli N,Felisati G,Pietrogrande MC

更新日期：2003-12-01 00:00:00

abstract：:Skinfold standards provide a useful indication of subcutaneous fat. To evaluate skinfold thickness of 252 Cambridge infants over the first 2 years of age, SD scores relative to the Tanner standards were calculated, taking account of skewness in the standards. Cambridge SD scores were low, varying according to age from...

journal_title：Archives of disease in childhood

authors： Paul AA,Cole TJ,Ahmed EA,Whitehead RG

更新日期：1998-04-01 00:00:00

abstract：:The association of weight for height and triceps skinfold with seven respiratory symptoms has been examined using logistic regression analysis in 7800 5 to 11 year old children (6200 in England and 1600 in Scotland). The results support the view that overweight children have a greater liability to some respiratory sym...

journal_title：Archives of disease in childhood

authors： Somerville SM,Rona RJ,Chinn S

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:To assess the natural history of respiratory symptoms not labelled as asthma in primary schoolchildren. DESIGN:Repeat questionnaire survey of subgroups identified from a previous questionnaire survey after a two year delay. SUBJECTS:The original population of 5321 Sheffield children aged 8-9 years yielded 4...

journal_title：Archives of disease in childhood

authors： Powell CV,Primhak RA

更新日期：1996-11-01 00:00:00

abstract：:Sixteen children who had had congenital diaphragmatic herniae repaired either in the neonatal period (11), or in early childhood (5), were reviewed at between 7 and 19 years of age. Only minor abnormalities were shown in their chest x-rays and in a variety of lung function tests. This suggests that the long-term progn...

journal_title：Archives of disease in childhood

authors： Kerr AA

更新日期：1977-11-01 00:00:00