Psychiatric adverse drug reactions in the paediatric population.

abstract：AIM:To evaluate the risk factors for breakthrough varicella in a follow up study of a cohort of 181 healthy children immunised when aged 9-24 months with a reformulated Oka strain varicella vaccine (SmithKline Beecham Biologicals/Oka). DESIGN:The children were randomised in a double blind manner into one of four group...

journal_title：Archives of disease in childhood

authors： Lim YJ,Chew FT,Tan AY,Lee BW

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:Despite growing interest in children and young people's (CYP) perspectives on healthcare, they continue to be excluded from many patient experience surveys. This study investigated the feasibility of, and additional information gained by, measuring CYP experiences of a recent hospital admission. DESIGN:Cross...

journal_title：Archives of disease in childhood

authors： Hargreaves DS,Sizmur S,Pitchforth J,Tallett A,Toomey SL,Hopwood B,Schuster MA,Viner RM

更新日期：2018-05-01 00:00:00

abstract：:Life was sorted. With membership of the college under my belt, and my paediatric training completed, I needed a new challenge. I decided to launch into the deep waters of qualitative research. Stepping out with some trepidation into semistructured interviews and grounded theory, I soon found that the water was neither...

journal_title：Archives of disease in childhood

authors： Sidebotham P

更新日期：2003-01-01 00:00:00

abstract：:Concentrations of chorionic somatomammotrophin (hCS) in maternal plasma at the time of delivery and in placental extracts were determined by radioimmunoassay and related to neonatal growth in 111 normal pregnancies. Mean maternal plasma hCS concentration was lower in association with small-for-dates infants, defined b...

journal_title：Archives of disease in childhood

authors： Macmillian DR,Hawkins R,Collier RN

更新日期：1976-02-01 00:00:00

abstract：:The role of inflammation in adult asthma is well known, involving a cascade of immunological stimulation in which mast cells and eosinophils play pivotal roles. However, the assessment of airway inflammation in children is more difficult as the invasive methods used in adults cannot ethically be used for this purpose ...

journal_title：Archives of disease in childhood

authors： Chedevergne F,Le Bourgeois M,de Blic J,Scheinmann P

更新日期：2000-06-01 00:00:00

abstract：RATIONALE:Studies suggest that increased breastfeeding rates can provide substantial financial savings, but the scale of such savings in the UK is not known. OBJECTIVE:To calculate potential cost savings attributable to increases in breastfeeding rates from the National Health Service perspective. DESIGN AND SETTINGS...

journal_title：Archives of disease in childhood

authors： Pokhrel S,Quigley MA,Fox-Rushby J,McCormick F,Williams A,Trueman P,Dodds R,Renfrew MJ

更新日期：2015-04-01 00:00:00

abstract：:An epidemiological study of disease in a geographically identified population of 250 children is reported. 22% had not seen their general practitioner (GP) at all in the past year, while 20% had seen him four times or more. The vast majority of these visits were because of an infective illness; and developmental and b...

journal_title：Archives of disease in childhood

authors： Bax M,Hart H

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVE:To explore the effect of research ethics, governance and consent requirements and recent reforms on UK-wide follow-up of children with congenital heart defects (CHD). DESIGN:Prospective cohort study. SETTING:UK National Health Service. PATIENTS:3897 children with CHD requiring intervention, or resulting in...

journal_title：Archives of disease in childhood

authors： Knowles RL,Bull C,Wren C,Dezateux C

更新日期：2011-01-01 00:00:00

abstract：:Increased emphasis on strict glycaemic control of insulin dependent diabetes mellitus (IDDM) in young patients may be expected to cause increases in rates of significant hypoglycaemia. To evaluate whether this is the case for a large population based sample of IDDM children and adolescents rates of severe (coma, convu...

journal_title：Archives of disease in childhood

authors： Davis EA,Keating B,Byrne GC,Russell M,Jones TW

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:A tailor-made serogroup B outer membrane vesicle vaccine was evaluated in the context of a serogroup B meningococcal epidemic dominated by Neisseria meningitidis strain B:4:P1.7b,4. OBJECTIVE:To determine the safety, reactogenicity and immunogenicity in infants aged 6-8 months of a meningococcal B vaccine d...

journal_title：Archives of disease in childhood

authors： Jackson C,Lennon DR,Sotutu VT,Yan J,Stewart JM,Reid S,Crengle S,Oster P,Ypma E,Aaberge I,Mulholland K,Martin DR

更新日期：2009-10-01 00:00:00

abstract：:Screening for hearing loss in the first year of life, using the distraction test, remains the responsibility of health visitors in most health districts in the United Kingdom. We have evaluated the screening procedure used routinely in one health region in a population of infants at increased risk of sensorineural dea...

journal_title：Archives of disease in childhood

authors： Johnson A,Ashurst H

更新日期：1990-08-01 00:00:00

abstract：AIMS:To investigate a population of individuals with 22q11 deletion syndrome for hypocalcaemia. METHODS:A detailed clinical history enquiring into symptoms of hypocalcaemia and blood sampling to assess for hypocalcaemia and hypoparathyroidism, of patients outside the neonatal period known to have the 22q11 microdeleti...

journal_title：Archives of disease in childhood

authors： Taylor SC,Morris G,Wilson D,Davies SJ,Gregory JW

更新日期：2003-06-01 00:00:00

abstract：:The clinical, radiological, and biochemical features of 2 male children with mannosidosis are described. Superficially they appeared to suffer from Hurler's syndrome, but the facies, eye signs, radiological and cytological features were atypical. Excess urinary oligosaccharides were found by thin-layer chromatography....

journal_title：Archives of disease in childhood

authors： Milla PJ,Black IE,Patrick AD,Hugh-Jones K,Oberholzer V

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:The management of subclinical hypothyroidism (SH) is still controversial, as the benefit to risk ratio of prolonged L-thyroxine therapy is not clear cut. Some authors have shown abnormalities of myocardial function and structure in adults with SH, which could be reversed by L-thyroxine therapy. As SH frequen...

journal_title：Archives of disease in childhood

authors： Toscano E,Pacileo G,Limongelli G,Verrengia M,Di Mita O,Di Maio S,Salerno M,Del Giudice E,Caniello B,Calabrò R,Andria G

更新日期：2003-11-01 00:00:00

abstract：:Eighty four very low birthweight babies (considered high risk for developing necrotising enterocolitis) were given vancomycin orally for 48 hours before introduction of oral feeds; one developed necrotising enterocolitis. One hundred and twenty very low birthweight babies (not considered such high risk) were fed witho...

journal_title：Archives of disease in childhood

authors： Ng PC,Dear PR,Thomas DF

更新日期：1988-11-01 00:00:00

abstract：INTRODUCTION:Propylene glycol (PG) is an unintentional frequently administered solvent in neonates despite the fact that PG accumulation potentially results in hyperosmolarity, lactic acidosis and renal/hepatic toxicity. METHODS:Prospective evaluation of renal (diuresis, creatinaemia, sodium), metabolic (base excess, ...

journal_title：Archives of disease in childhood

authors： Allegaert K,Vanhaesebrouck S,Kulo A,Cosaert K,Verbesselt R,Debeer A,de Hoon J

更新日期：2010-12-01 00:00:00

abstract：AIMS:To determine the prevalence of petechial spots in well babies. METHODS:A total of 116 babies under the age of 12 months were fully examined at child health surveillance clinics. The number and site of petechiae were recorded together with details of possible causes. RESULTS:A total of 27.6% of babies had one or ...

journal_title：Archives of disease in childhood

authors： Downes AJ,Crossland DS,Mellon AF

更新日期：2002-04-01 00:00:00

abstract：:Ethical considerations have long been a part of clinical decision making. However, just as doctors and healthcare professionals are being increasingly challenged about the evidence base for their practice, there is increasing focus on the ethical dimension of clinical care. ...

journal_title：Archives of disease in childhood

authors： Watson AR

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:To investigate the prevalence of infant crying and maternal soothing techniques in relation to ethnic origin and other sociodemographic variables. DESIGN:A questionnaire survey among mothers of 2-3 month old infants registered at six child health clinics in Amsterdam, the Netherlands. SUBJECTS:A questionna...

journal_title：Archives of disease in childhood

authors： van der Wal MF,van den Boom DC,Pauw-Plomp H,de Jonge GA

更新日期：1998-10-01 00:00:00

abstract：:In 1973 a survey was conducted among 12 year old children living in a defined area of South Wales. In 1988 the survey was repeated in the same area, again among 12 year old children. Questionnaires were completed for all 965 children in the population sample; peak expiratory flow rates were performed on them all, and ...

journal_title：Archives of disease in childhood

authors： Burr ML,Butland BK,King S,Vaughan-Williams E

更新日期：1989-10-01 00:00:00

abstract：:In a family in which the father carried a balanced translocation between chromosomes 15 and 22 two of his children had Prader-Willi syndrome and an unbalanced chromosome complement, having lost the proximal bands from the long arm of chromosome 15. His four other surviving children were normal but carried a balanced t...

journal_title：Archives of disease in childhood

authors： Fernandez F,Berry C,Mutton D

更新日期：1987-08-01 00:00:00

abstract：AIM:Several studies have suggested a beneficial effect of infant breastfeeding on childhood cognitive function. The main objective was to examine whether duration of breastfeeding and age at introduction of complementary foods are related to cognitive performance in 9- to 10-year-old school-aged children in South India...

journal_title：Archives of disease in childhood

authors： Veena SR,Krishnaveni GV,Srinivasan K,Wills AK,Hill JC,Kurpad AV,Muthayya S,Karat SC,Nalinakshi M,Fall CH

更新日期：2010-05-01 00:00:00

abstract：:A method for securing umbilical catheters is described. It has been used successfully in over 350 babies. It is a simple and rapid method that allows for easy repositioning and, unlike some established techniques, has no potential for damage to the preterm baby's skin. ...

journal_title：Archives of disease in childhood

authors： South M,Magnay A

更新日期：1988-07-01 00:00:00

abstract：:Cerebral palsy comprises an important component of paediatric and obstetric practice and has major medico-legal implications. The prognosis for survival in cerebral palsy determines the financial provision made in cases that come to litigation. Issues of data quality and estimation methods are critical. Estimating the...

journal_title：Archives of disease in childhood

authors： Hutton JL,Pharoah PO

更新日期：2006-03-01 00:00:00

abstract：:Many children admitted to hospital can stay for 24 hours or less. Short stay facilities offer such children rapid stabilisation and early discharge with considerable financial saving. A 12 month study was completed in which data were collected from the children's emergency annex (CEA) at Westmead Hospital in Sydney's ...

journal_title：Archives of disease in childhood

authors： Browne GJ,Penna A

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Following recent reports of increased numbers of adolescents being diagnosed with the adult or type 2 form of diabetes we aimed to describe the prevalence of both type 2 and other forms of diabetes in an urban population of children and young people in northern England. METHODS:A hospital based cro...

journal_title：Archives of disease in childhood

authors： Feltbower RG,McKinney PA,Campbell FM,Stephenson CR,Bodansky HJ

更新日期：2003-08-01 00:00:00

abstract：:Clinical trials in children in resource-poor environments are essential for local health policy and practice to be relevant and evidence based. Research must be ethical, appropriate, relevant and of good quality. It should, where possible, benefit the subjects studied,the clinical, scientific and support staff involve...

journal_title：Archives of disease in childhood

authors： Molyneux E,Mathanga D,Witte D,Molyneux M

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To determine the effectiveness of auditory integration training (AIT) or other methods of sound therapy in people with autism spectrum disorders (ASD). STUDY DESIGN:A systematic review was carried out of randomised controlled trials (RCTs) of adults or children with ASD. Meta-analysis was attempted. RESULT...

journal_title：Archives of disease in childhood

authors： Sinha Y,Silove N,Wheeler D,Williams K

更新日期：2006-12-01 00:00:00

abstract：:A 24 hour energy balance study was carried out on 20 black Kenyan children with acute measles and repeated after recovery. The energy content of a weighed 24 hour food intake and of a simultaneous collection of faeces and urine was determined by bomb calorimetry. Energy expenditure was measured by indirect calorimetry...

journal_title：Archives of disease in childhood

authors： Duggan MB,Alwar J,Milner RD

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Perinatal stress is thought to underlie the Barker sequelae of low birth weight, of which precocious pubarche may be a manifestation. AIMS:To explore whether prematurity as well as smallness for gestational age (SGA) predisposes to precocious pubarche, and the potential role of excess weight gain during chi...

journal_title：Archives of disease in childhood

authors： Neville KA,Walker JL

更新日期：2005-03-01 00:00:00